DK0698029T3 - Fremgangsmåde til fremstilling af azamakrocykliske eller acykliske aminophosphonatesterderivater - Google Patents

Fremgangsmåde til fremstilling af azamakrocykliske eller acykliske aminophosphonatesterderivater

Info

Publication number
DK0698029T3
DK0698029T3 DK94917333T DK94917333T DK0698029T3 DK 0698029 T3 DK0698029 T3 DK 0698029T3 DK 94917333 T DK94917333 T DK 94917333T DK 94917333 T DK94917333 T DK 94917333T DK 0698029 T3 DK0698029 T3 DK 0698029T3
Authority
DK
Denmark
Prior art keywords
azamacrocyclic
preparation
ester derivatives
aminophosphonate ester
acyclic aminophosphonate
Prior art date
Application number
DK94917333T
Other languages
Danish (da)
English (en)
Inventor
E Kiefer Garry
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of DK0698029T3 publication Critical patent/DK0698029T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94917333T 1993-05-06 1994-05-04 Fremgangsmåde til fremstilling af azamakrocykliske eller acykliske aminophosphonatesterderivater DK0698029T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/065,963 US5714604A (en) 1993-05-06 1993-05-06 Process for the preparation of azamacrocyclic or acyclic aminophosphonate ester derivatives
PCT/US1994/005134 WO1994026753A1 (fr) 1993-05-06 1994-05-04 Procede de preparation de derives d'ester d'aminophosphonate azamacrocyclique ou acyclique

Publications (1)

Publication Number Publication Date
DK0698029T3 true DK0698029T3 (da) 1999-07-19

Family

ID=22066341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94917333T DK0698029T3 (da) 1993-05-06 1994-05-04 Fremgangsmåde til fremstilling af azamakrocykliske eller acykliske aminophosphonatesterderivater

Country Status (35)

Country Link
US (1) US5714604A (fr)
EP (1) EP0698029B1 (fr)
JP (1) JP3556669B2 (fr)
KR (1) KR100311560B1 (fr)
CN (1) CN1042537C (fr)
AP (1) AP543A (fr)
AT (1) ATE172978T1 (fr)
AU (1) AU682190B2 (fr)
BG (1) BG62775B1 (fr)
CA (1) CA2162170C (fr)
CO (1) CO4230080A1 (fr)
CZ (1) CZ290993B6 (fr)
DE (1) DE69414382T2 (fr)
DK (1) DK0698029T3 (fr)
DZ (1) DZ1777A1 (fr)
EE (1) EE03159B1 (fr)
EG (1) EG20296A (fr)
ES (1) ES2123137T3 (fr)
FI (1) FI115632B (fr)
HK (1) HK1014537A1 (fr)
HU (1) HU223769B1 (fr)
IL (1) IL109561A (fr)
IS (1) IS1735B (fr)
LT (1) LT3713B (fr)
LV (1) LV10867B (fr)
MA (1) MA23186A1 (fr)
NO (1) NO304742B1 (fr)
PL (1) PL180756B1 (fr)
RO (1) RO115883B1 (fr)
RU (1) RU2135507C1 (fr)
TN (1) TNSN94040A1 (fr)
TW (1) TW273549B (fr)
UA (1) UA44704C2 (fr)
WO (1) WO1994026753A1 (fr)
ZA (1) ZA943158B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207826B1 (en) 1995-03-27 2001-03-27 Isis Pharmaceuticals, Inc. Macrocyclic compounds having nitrogen-containing linkages
US6107482A (en) * 1995-03-27 2000-08-22 Isis Pharmaceuticals, Inc. Nitrogenous macrocyclic compounds
EP1191948A2 (fr) * 1999-06-11 2002-04-03 Neorx Corporation Complexe a forte dose de radionucleides destine a la suppression de la moelle osseuse
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
CN1378454A (zh) * 1999-10-18 2002-11-06 陶氏化学公司 治疗骨质失调的氨亚烷基膦酸酯
US6794371B1 (en) * 1999-10-18 2004-09-21 The Dow Chemical Company Aminoalkylenephosphonates for treatment of bone disorders
US6565828B2 (en) * 2000-04-07 2003-05-20 Bristol-Myers Squibb Company Macrocyclic chelants for metallopharmaceuticals
AU2002249935A1 (en) 2001-01-08 2002-08-19 Neorx Corporation Radioactively labelled conjugates of phosphonates
US20030133872A1 (en) * 2001-10-22 2003-07-17 Kiefer Garry E. Radiopharmaceutical agent for the treatment of early stage cancer
JP2005507005A (ja) * 2001-10-22 2005-03-10 テキサス テック ユニバーシティー 組織特異的螢光キレート
WO2003051403A1 (fr) 2001-12-13 2003-06-26 Dow Global Technologies Inc. Traitement de l'osteomyelite avec des produits radiopharmaceutiques
US20050112066A1 (en) * 2003-11-26 2005-05-26 Concat Lp, A California Limited Partnership Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity
EP1778699A4 (fr) * 2004-08-10 2009-02-25 Dow Global Technologies Inc Chelateurs et composes chelates de ciblage
CN112442069A (zh) * 2019-08-28 2021-03-05 广东广山新材料股份有限公司 一种带有胺基的含磷阻燃剂及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362476A (en) * 1984-10-18 1994-11-08 Board Of Regents, The University Of Texas System Alkyl phosphonate polyazamacrocyclic cheates for MRI
GB8817185D0 (en) * 1988-07-19 1988-08-24 Interox Chemicals Ltd Organic polyphosphonates
GB8903023D0 (en) * 1989-02-10 1989-03-30 Parker David Chemical compounds
US5342936A (en) * 1989-02-10 1994-08-30 David Parker Tetra-aza macrocycles and processes for their preparation
US5236695A (en) * 1989-11-27 1993-08-17 Concat, Ltd. MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands
WO1991007911A1 (fr) * 1989-11-27 1991-06-13 Concat Ltd. Ameloration d'images d'irm d'os et de tissus apparentes a l'aide de complexes de cations paramagnetiques et de ligands de polyphosphonate
US5385893A (en) * 1993-05-06 1995-01-31 The Dow Chemical Company Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
US5606053A (en) * 1995-05-02 1997-02-25 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane

Also Published As

Publication number Publication date
IS1735B (is) 1999-12-14
CA2162170C (fr) 2005-03-15
EP0698029B1 (fr) 1998-11-04
DE69414382D1 (de) 1998-12-10
DE69414382T2 (de) 1999-03-25
NO954439L (no) 1996-01-05
FI955281A (fi) 1995-12-20
EG20296A (en) 1998-10-31
BG100193A (bg) 1996-12-31
LTIP1925A (en) 1995-01-31
TNSN94040A1 (fr) 1995-04-25
HU9503175D0 (en) 1995-12-28
HU223769B1 (hu) 2005-01-28
CZ289095A3 (en) 1996-03-13
JPH08510249A (ja) 1996-10-29
KR100311560B1 (ko) 2001-12-28
LT3713B (en) 1996-02-26
FI955281A0 (fi) 1995-11-03
CN1125949A (zh) 1996-07-03
ATE172978T1 (de) 1998-11-15
IL109561A0 (en) 1994-08-26
IL109561A (en) 2002-07-25
FI115632B (fi) 2005-06-15
LV10867A (lv) 1995-10-20
AP9400639A0 (en) 1994-07-31
AU682190B2 (en) 1997-09-25
CZ290993B6 (cs) 2002-11-13
UA44704C2 (uk) 2002-03-15
BG62775B1 (bg) 2000-07-31
EP0698029A1 (fr) 1996-02-28
RO115883B1 (ro) 2000-07-28
HUT73142A (en) 1996-06-28
CN1042537C (zh) 1999-03-17
AU6908694A (en) 1994-12-12
NO304742B1 (no) 1999-02-08
TW273549B (fr) 1996-04-01
ES2123137T3 (es) 1999-01-01
LV10867B (en) 1996-08-20
RU2135507C1 (ru) 1999-08-27
DZ1777A1 (fr) 2002-02-17
US5714604A (en) 1998-02-03
PL180756B1 (pl) 2001-04-30
WO1994026753A1 (fr) 1994-11-24
PL311651A1 (en) 1996-03-04
CO4230080A1 (es) 1995-10-19
EE03159B1 (et) 1999-02-15
MA23186A1 (fr) 1994-12-31
CA2162170A1 (fr) 1994-11-24
KR960702469A (ko) 1996-04-27
IS4158A (is) 1994-11-07
NO954439D0 (no) 1995-11-06
JP3556669B2 (ja) 2004-08-18
ZA943158B (en) 1995-11-06
HK1014537A1 (en) 1999-09-30
AP543A (en) 1996-10-09

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