DE69304839D1 - Verfahren zur Herstellung von Nukleosidderivaten - Google Patents

Verfahren zur Herstellung von Nukleosidderivaten

Info

Publication number
DE69304839D1
DE69304839D1 DE69304839T DE69304839T DE69304839D1 DE 69304839 D1 DE69304839 D1 DE 69304839D1 DE 69304839 T DE69304839 T DE 69304839T DE 69304839 T DE69304839 T DE 69304839T DE 69304839 D1 DE69304839 D1 DE 69304839D1
Authority
DE
Germany
Prior art keywords
preparation
nucleoside derivatives
nucleoside
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69304839T
Other languages
English (en)
Other versions
DE69304839T2 (de
Inventor
Hiroshi Shiragami
Masayuki Arai
Kunisuke Izawa
Yutaka Honda
Yasuhiro Tanaka
Toshihide Yukawa
Satoji Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP04199965A external-priority patent/JP3123239B2/ja
Priority claimed from JP04199964A external-priority patent/JP3123238B2/ja
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of DE69304839D1 publication Critical patent/DE69304839D1/de
Publication of DE69304839T2 publication Critical patent/DE69304839T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
DE69304839T 1992-07-27 1993-07-23 Verfahren zur Herstellung von Nukleosidderivaten Expired - Lifetime DE69304839T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP04199965A JP3123239B2 (ja) 1992-07-27 1992-07-27 ヌクレオシド誘導体の樹脂精製法
JP04199964A JP3123238B2 (ja) 1992-07-27 1992-07-27 ヌクレオシド誘導体の精製法

Publications (2)

Publication Number Publication Date
DE69304839D1 true DE69304839D1 (de) 1996-10-24
DE69304839T2 DE69304839T2 (de) 1997-04-30

Family

ID=26511865

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69304839T Expired - Lifetime DE69304839T2 (de) 1992-07-27 1993-07-23 Verfahren zur Herstellung von Nukleosidderivaten

Country Status (5)

Country Link
US (1) US5451671A (de)
EP (1) EP0582157B1 (de)
CA (1) CA2101281C (de)
DE (1) DE69304839T2 (de)
ES (1) ES2092191T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090937A (en) * 1998-03-17 2000-07-18 Ajinomoto Co., Inc. Methods for producing nucleoside derivatives and intermediates therefor
EP1910393A2 (de) * 2005-07-05 2008-04-16 Hetero Drugs Limited Neues verfahren zur herstellung von didanosin unter verwendung neuer zwischenprodukte
BRPI0721308A2 (pt) * 2007-01-19 2014-03-25 Ajinomoto Kk Método para produzir cristais de um composto de purina nucleosídeo.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
EP0199451B1 (de) * 1985-03-16 1996-03-06 The Wellcome Foundation Limited Therapeutische Nukleoside
ATE190064T1 (de) * 1985-09-17 2000-03-15 Wellcome Found Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten.
JPH0691830B2 (ja) * 1987-12-22 1994-11-16 味の素株式会社 ジデオキシイノシンの精製法
JPH0710236B2 (ja) * 1987-10-12 1995-02-08 味の素株式会社 ジデオキシアデノシンの精製方法
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
JPH01102095A (ja) * 1987-10-14 1989-04-19 Ajinomoto Co Inc ジデオキシウリジンの精製方法
US4833924A (en) * 1987-10-30 1989-05-30 Robertshaw Controls Company Differential pressure transmitter, a square root extractor device therefor and methods of making the same
US4997926A (en) * 1987-11-18 1991-03-05 Scripps Clinic And Research Foundation Deaminase-stable anti-retroviral 2-halo-2',3'-dideoxy
JPH0826020B2 (ja) * 1987-12-29 1996-03-13 味の素株式会社 ジデオキシイノシンの精製方法
JPH0717670B2 (ja) * 1988-03-01 1995-03-01 味の素株式会社 ヌクレオシド誘導体の製造方法
JPH02204489A (ja) * 1989-02-02 1990-08-14 Ajinomoto Co Inc 易溶性２’，３’―ジデオキシイノシン、その製造法及び２’，３’―ジデオキシイノシン水性溶液の製造法
JPH02243690A (ja) * 1989-03-15 1990-09-27 Daicel Chem Ind Ltd ヌクレオシド誘導体の製造法

Also Published As

Publication number Publication date
US5451671A (en) 1995-09-19
DE69304839T2 (de) 1997-04-30
EP0582157B1 (de) 1996-09-18
ES2092191T3 (es) 1996-11-16
CA2101281C (en) 2003-11-04
CA2101281A1 (en) 1994-01-28
EP0582157A1 (de) 1994-02-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition