DK0677044T3 - Fremgangsmåde til udvinding af cellebestanddele in vivo - Google Patents

Fremgangsmåde til udvinding af cellebestanddele in vivo

Info

Publication number
DK0677044T3
DK0677044T3 DK94903874T DK94903874T DK0677044T3 DK 0677044 T3 DK0677044 T3 DK 0677044T3 DK 94903874 T DK94903874 T DK 94903874T DK 94903874 T DK94903874 T DK 94903874T DK 0677044 T3 DK0677044 T3 DK 0677044T3
Authority
DK
Denmark
Prior art keywords
vivo
state
cellular components
cell contents
extracting cellular
Prior art date
Application number
DK94903874T
Other languages
Danish (da)
English (en)
Inventor
Erwin A Galinski
Hans G Truper
Thomas Sauer
A Galinski Erwin
G Truper Hans
Original Assignee
Bitop Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bitop Gmbh filed Critical Bitop Gmbh
Application granted granted Critical
Publication of DK0677044T3 publication Critical patent/DK0677044T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK94903874T 1992-12-31 1993-12-24 Fremgangsmåde til udvinding af cellebestanddele in vivo DK0677044T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4244580A DE4244580A1 (de) 1992-12-31 1992-12-31 Verfahren zur in vivo Gewinnung von Inhaltsstoffen aus Zellen
PCT/EP1993/003687 WO1994015923A2 (de) 1992-12-31 1993-12-24 Verfahren zur in vivo gewinnung von inhaltsstoffen aus zellen

Publications (1)

Publication Number Publication Date
DK0677044T3 true DK0677044T3 (da) 1999-07-12

Family

ID=6476850

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94903874T DK0677044T3 (da) 1992-12-31 1993-12-24 Fremgangsmåde til udvinding af cellebestanddele in vivo
DK98113132T DK0887418T3 (da) 1992-12-31 1993-12-24 Anvendelse af ectoin og hydroxyectoin som lægemiddel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK98113132T DK0887418T3 (da) 1992-12-31 1993-12-24 Anvendelse af ectoin og hydroxyectoin som lægemiddel

Country Status (7)

Country Link
EP (4) EP0677044B1 (es)
AT (3) ATE226943T1 (es)
DE (4) DE4244580A1 (es)
DK (2) DK0677044T3 (es)
ES (2) ES2186059T3 (es)
PT (1) PT887418E (es)
WO (1) WO1994015923A2 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4342560A1 (de) 1993-12-14 1995-06-22 Marbert Gmbh Ectoin und Ectoinderivate als Feuchtigkeitsspender in Kosmetikprodukten
DE4427617B4 (de) * 1994-08-04 2005-09-01 bitop Aktiengesellschaft für biotechnische Optimierung Verfahren zur Gewinnung von Zellinhaltsstoffen aus halophilen und osmophilen sowie halo- und osmotoleranten Mikroorganismen
DE19711082A1 (de) * 1997-03-18 1998-09-24 Degussa Verfahren zur Abtrennung von Tetrahydropyrimidinen aus wäßrigen Lösungen
AU5812800A (en) 1999-06-12 2001-01-02 Stefan Barth Pharmaceutical preparation
EP1125583A1 (de) * 2000-02-14 2001-08-22 Bitop Gesellschaft für biotechnische Optimierung MbH Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren
DE10014632A1 (de) * 2000-03-24 2001-09-27 Merck Patent Gmbh Verwendung von Ectoin oder Ectoin-Derivaten zum Schutz der Streßproteine in der Haut
US7048910B2 (en) 2000-09-07 2006-05-23 Merck Patent Gmbh Use of ectoine or ectoine derivatives for oral care
DE10214257A1 (de) 2002-03-28 2003-10-16 Merck Patent Gmbh Verwendung von kompatiblen Soluten zur Inhibierung der Freisetzung von Ceramiden
DE10330768A1 (de) 2003-07-07 2005-02-24 bitop Aktiengesellschaft für biotechnische Optimierung Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von inhalierbaren Arzneimitteln zur Prophylaxe und Behandlung pulmonaler und kardiovaskulärer Erkrankungen, sowie eines Osmolyte als Wirkstoffbestandteil enthaltende Inhalationsvorrichtung
JP4896006B2 (ja) 2004-04-08 2012-03-14 バイオマトリカ, インコーポレイテッド ライフサイエンスのためのサンプル保存とサンプル管理との統合
DE102006060953A1 (de) 2006-12-12 2008-08-07 Farco-Pharma Gmbh Pharmazeutische Zubereitung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes
DE102007003765A1 (de) 2007-01-19 2008-07-24 Farco-Pharma Gmbh Pharmazeutische Zusammensetzung zur Behandlung von Inkontinenz
DE102007013857A1 (de) 2007-03-20 2008-09-25 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue Zusammensetzungen, insbesondere für die topische Behandlung von Hauterkrankungen
DE102007052380A1 (de) 2007-10-31 2009-05-07 Bitop Ag Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten
DE102008006780A1 (de) * 2008-01-30 2009-08-06 Bitop Ag Verwendung von Tetrahydropyrimidinen
DE102008036725B4 (de) 2008-08-07 2021-01-28 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Pharmazeutische Zusammensetzung für die nasale Applikation
DE102008045237B4 (de) 2008-08-28 2010-07-29 Helmholtz-Zentrum Für Umweltforschung Gmbh - Ufz Verfahren zur simultanen Produktion von PHA und kompatiblen Soluten in halophilen Bakterien
EP2168570B1 (en) 2008-09-30 2013-12-25 Symrise AG Extracts of isochrysis sp.
EP2193785B1 (en) 2008-12-05 2018-07-18 Symrise AG Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes
DE102010010279A1 (de) * 2009-03-07 2010-09-16 Hertel, Marcus, Dr. Ing. Verfahren und Vorrichtung zur Behandlung von Getränken
US8519125B2 (en) 2009-05-11 2013-08-27 Biomatrica, Inc. Compositions and methods for biological sample storage
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
DE102011113059A1 (de) 2011-09-09 2013-03-14 Bitop Ag Therapeutische Anwendungen von Ectoin
DE102012000416A1 (de) 2011-11-24 2013-05-29 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Zusammensetzung für die topische Applikation II
DE102012000430B4 (de) 2011-11-24 2021-11-04 Farco-Pharma Gmbh Zusammensetzung für die topische Anwendung I
DE102011122236A1 (de) 2011-12-09 2013-06-13 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Zusammensetzung für die topische Anwendung bei entzündlichen Erkrankungen der Haut und/oder Schleimhaut
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
DE102012005177A1 (de) * 2012-03-16 2013-09-19 Bitop Ag Organlagerlösung
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
ES2701758T3 (es) 2013-02-27 2019-02-25 Symrise Ag Extracto de jengibre para la protección de citoblastos
EP2862852B1 (en) 2013-10-18 2018-07-04 Symrise AG Urea derivatives for the protection of stem cells
ES2643590T3 (es) 2014-03-18 2017-11-23 Symrise Ag Dióxido de titanio revestido para reducir el efecto de blanqueamiento en la piel
ES2819207T3 (es) 2014-04-29 2021-04-15 Symrise Ag Mezclas activas
CN106572650B (zh) 2014-06-10 2021-08-31 生物马特里卡公司 在环境温度下稳定凝血细胞
EP3045161A1 (en) 2015-01-18 2016-07-20 Symrise AG Active compositions comprising 1,2-hexanediol and 1,2-octanediol
EP4242628A3 (en) 2015-12-08 2023-11-08 Biomatrica, INC. Reduction of erythrocyte sedimentation rate
DE102017105010A1 (de) 2017-02-24 2018-08-30 Farco-Pharma Gmbh Zusammensetzung, insbesondere Gel, zur Anwendung im Urogenitaltrakt
US20200030214A1 (en) 2017-03-06 2020-01-30 Merck Patent Gmbh Use of compatible solutes
CN107333750A (zh) * 2017-06-11 2017-11-10 成都吱吖科技有限公司 一种长时血液细胞稳定剂
KR20220042171A (ko) 2019-08-01 2022-04-04 메르크 파텐트 게엠베하 각질화 장애의 예방 및 감소 및 관련 미용제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286660A (en) * 1979-03-23 1981-09-01 Gesellschaft Fur Biotechnologische Forschung Gmbh Process and installation for the flooding of petroleum deposits and oil shale
US4720458A (en) * 1983-10-19 1988-01-19 Sullivan Cornelius W Heat sensitive bacterial alkaline phosphatase
DE3515650A1 (de) * 1985-05-02 1986-11-06 Biochemie GmbH, Kundl, Tirol Verfahren zur abtrennung von biotechnologisch hergestellten wertstoffen durch querstrom-mikrofiltration
JPH0759545B2 (ja) * 1987-06-17 1995-06-28 富士写真フイルム株式会社 塩基プレカ−サ−
FR2635113B1 (fr) * 1988-08-05 1992-07-24 Sanofi Sa Procede d'obtention d'interleukine-1 (beta) mature a partir de cellules d'e. coli transformees
JPH0331265A (ja) * 1989-06-26 1991-02-12 Takeda Chem Ind Ltd テトラヒドロピリミジン誘導体の製造方法
WO1992004054A1 (en) * 1990-08-30 1992-03-19 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITY, PORTLAND, OREGON, and THE UNIVERSITY OF OREGON, EUGENE, OREGON, Johnson Hall, University of Oregon Substituted amidines having high binding to the sigma receptor and the use thereof
IL100810A (en) * 1992-01-30 1996-12-05 Yeda Res & Dev Pharmaceutical preparations including 2 - methyl - carboxy - 5 - hydroxy - tetrahydropyrimidine and / or 2 - methyl - 4 - carboxy - tetrahydropyrimidine, plywood methods

Also Published As

Publication number Publication date
DE4244580A1 (de) 1994-07-07
ATE284448T1 (de) 2004-12-15
ES2186059T3 (es) 2003-05-01
EP0887418B1 (de) 2002-10-30
EP0915167B1 (de) 2004-12-08
DK0887418T3 (da) 2003-02-24
EP0887418A2 (de) 1998-12-30
EP0677044B1 (de) 1998-10-28
EP0677044A1 (de) 1995-10-18
EP0915167A1 (de) 1999-05-12
ES2234065T3 (es) 2005-06-16
PT887418E (pt) 2003-03-31
DE59310369D1 (de) 2005-01-13
EP1493432A1 (de) 2005-01-05
DE59309101D1 (de) 1998-12-03
WO1994015923A3 (de) 1994-09-29
DE59310311D1 (de) 2002-12-05
WO1994015923A2 (de) 1994-07-21
ATE172750T1 (de) 1998-11-15
ATE226943T1 (de) 2002-11-15
EP0887418A3 (de) 1999-01-13

Similar Documents

Publication Publication Date Title
DK0677044T3 (da) Fremgangsmåde til udvinding af cellebestanddele in vivo
DE3581937D1 (de) Verfahren zur herstellung von modulen, aufgestapelte integrierte schaltungen enthalten.
NO995240L (no) Innretning for dyrking og/eller behandling av celler
HUP9800266A2 (hu) Eljárás szerves vegyületek kinyerésére oldataikból
DK551983D0 (da) Fremgangsmade til fremstilling af nitrogengas ved overatmosfaerisk tryk
DK0592434T3 (da) Forbedret fremgangsmåde til syntese af oligomerer
SE8302654D0 (sv) A method for producing ethanol from xylose-containing substance
BR9815314A (pt) Transdutor para transformação de séries de dados sintáticos
DE3673289D1 (de) Signalkodierung.
ATE18435T1 (de) Verfahren und vorrichtung zur hydrolytischen spaltung von cellulose.
BR0209743A (pt) Método e equipamento para buscar sequências de sincronização multiplexadas por divisão de tempo
DK161085C (da) Fremgangsmaade til fremstilling af nitrogengas ved overatmosfaerisk tryk
KR900009595A (ko) 2-클로로-5-클로로메틸피리딘의 제조방법
DK147640C (da) Fremgangsmaade til fremstilling af nitroimidazol-derivater
AT399885B (de) Verfahren zur herstellung von zellinien, die monoklonale antikörper produzieren
MX9301344A (es) Metodo para producir carbohidratos.
RU1816761C (ru) Способ получени замещенных 1-алкоксикарбонилметил-1,2-дигидро-3Н-1,4-бенздиазепин-2-онов
DK42083D0 (da) Fremgangsmade til fremstilling af et immunogen af pasteurella multocida
JPS5418630A (en) Character isolating process system
ATE104266T1 (de) 1-brom-3-chlor-1,2-diaryl-2-propanole, verfahren zur stereoselektiven herstellung der erythro-1- brom-3-chlor-1,2-diaryl-2-propanole und deren umsetzung zu azolylmethyloxiranen.
DE3784630D1 (de) Tri- oder tetra-2-hydroxybenzyl-1,2-diaminoalkan-derivate, verfahren zu ihrer herstellung und ihre verwendung fuer die extraktion von gallium.
JPS5213044A (en) Operation method of a hydraulic turbine
DEGASPERIS Backlund transformations: Tools to find novel integrable evolution equations
JPS52124751A (en) Method for treating waste water
JPS53139A (en) Beam splitter