DK0671922T3 - Fluidiseret intestinal submucosa og anvendelse deraf som et injicerbart vævstransplantat - Google Patents

Fluidiseret intestinal submucosa og anvendelse deraf som et injicerbart vævstransplantat

Info

Publication number
DK0671922T3
DK0671922T3 DK94900605T DK94900605T DK0671922T3 DK 0671922 T3 DK0671922 T3 DK 0671922T3 DK 94900605 T DK94900605 T DK 94900605T DK 94900605 T DK94900605 T DK 94900605T DK 0671922 T3 DK0671922 T3 DK 0671922T3
Authority
DK
Denmark
Prior art keywords
tissue graft
intestinal submucosa
fluidized
tissue
submucosa
Prior art date
Application number
DK94900605T
Other languages
English (en)
Inventor
Peter M Knapp Jr
Stephen F Badylak
Michael Hiles
Sherry Voytik
Robert J Demeter
Original Assignee
Purdue Research Foundation
Methodist Hospital Indiana
Peter M Knapp Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Methodist Hospital Indiana, Peter M Knapp Jr filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of DK0671922T3 publication Critical patent/DK0671922T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/367—Muscle tissue, e.g. sphincter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK94900605T 1992-11-13 1993-11-10 Fluidiseret intestinal submucosa og anvendelse deraf som et injicerbart vævstransplantat DK0671922T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/976,156 US5275826A (en) 1992-11-13 1992-11-13 Fluidized intestinal submucosa and its use as an injectable tissue graft
PCT/US1993/010861 WO1994011008A1 (en) 1992-11-13 1993-11-10 Fluidized intestinal submucosa and its use as an injectable tissue graft

Publications (1)

Publication Number Publication Date
DK0671922T3 true DK0671922T3 (da) 2000-08-28

Family

ID=25523793

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94900605T DK0671922T3 (da) 1992-11-13 1993-11-10 Fluidiseret intestinal submucosa og anvendelse deraf som et injicerbart vævstransplantat

Country Status (22)

Country Link
US (2) US5275826A (da)
EP (1) EP0671922B1 (da)
JP (1) JP3534408B2 (da)
AT (1) ATE192654T1 (da)
AU (1) AU677974B2 (da)
BR (1) BR9307419A (da)
CA (1) CA2149324C (da)
CZ (1) CZ124095A3 (da)
DE (1) DE69328625T2 (da)
DK (1) DK0671922T3 (da)
ES (1) ES2148309T3 (da)
FI (1) FI952337A (da)
GR (1) GR3034144T3 (da)
HU (1) HU218891B (da)
MX (1) MX9307046A (da)
NO (1) NO951881D0 (da)
NZ (2) NZ299279A (da)
PL (1) PL174426B1 (da)
PT (1) PT671922E (da)
RU (1) RU2148379C1 (da)
SK (1) SK282122B6 (da)
WO (1) WO1994011008A1 (da)

Families Citing this family (355)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5641518A (en) * 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US6653291B1 (en) 1992-11-13 2003-11-25 Purdue Research Foundation Composition and method for production of transformed cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US20020193338A1 (en) * 1994-02-18 2002-12-19 Goldstein Steven A. In vivo gene transfer methods for wound healing
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6334872B1 (en) * 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US6551618B2 (en) * 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6475232B1 (en) 1996-12-10 2002-11-05 Purdue Research Foundation Stent with reduced thrombogenicity
US5693085A (en) * 1994-04-29 1997-12-02 Scimed Life Systems, Inc. Stent with collagen
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
CA2173508A1 (en) * 1995-03-31 1996-10-01 Tooru Yui Medical device and method for producing the same
JPH11508151A (ja) * 1995-04-07 1999-07-21 パーデュー・リサーチ・ファウンデーション 膀胱再建方法及び膀胱再建用組織グラフト
US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
US5554389A (en) * 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
US5788625A (en) 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5755791A (en) * 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
US6171344B1 (en) 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
US20010048949A1 (en) * 1996-08-16 2001-12-06 Children's Medical Center Corporation Isolated bladder submucosa for tissue reconstruction
JP3816534B2 (ja) * 1996-08-16 2006-08-30 チルドレンズ メディカル センター コーポレーション 細胞を接種された組織再建術用膀胱粘膜下組織
US6666892B2 (en) * 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
PL331765A1 (en) 1996-08-23 1999-08-02 Cook Biotech Inc Trnsplant prosthesis, materials and methods
EP1430899B1 (en) * 1996-09-16 2010-07-07 Purdue Research Foundation Graft from submucosal intestinal tissue for repairing neurological tissue
DK0925067T3 (da) * 1996-09-16 2004-05-03 Purdue Research Foundation Graft fra submucosavæv til reparation af neurologisk væv
EP0936930B1 (en) * 1996-11-05 2004-07-28 Purdue Research Foundation Myocardial graft constructs
US6696270B2 (en) * 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
EP1014887B1 (en) 1996-12-10 2006-04-19 Purdue Research Foundation Stent with reduced thrombogenicity
WO1998025549A1 (en) 1996-12-10 1998-06-18 Purdue Research Foundation Artificial vascular valves
WO1998025637A1 (en) * 1996-12-10 1998-06-18 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
EP0944647B1 (en) 1996-12-10 2008-11-12 Purdue Research Foundation Submucosa extracts
US6099567A (en) * 1996-12-10 2000-08-08 Purdue Research Foundation Stomach submucosa derived tissue graft
EP1300154B1 (en) * 1996-12-10 2005-09-14 Purdue Research Foundation Stomach submucosa derived tissue graft
US6300127B1 (en) 1997-07-30 2001-10-09 Emory University Bone mineralization proteins, DNA, vectors, expression systems
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
US6331319B1 (en) 1997-09-11 2001-12-18 Purdue Research Foundation Galactosidase modified submucosal tissue
AU2090799A (en) 1997-12-23 1999-07-12 Purdue Research Foundation Biomaterial derived from follicle basement membranes
US7070607B2 (en) * 1998-01-27 2006-07-04 The Regents Of The University Of California Bioabsorbable polymeric implants and a method of using the same to create occlusions
AU772827B2 (en) * 1998-02-27 2004-05-06 Purdue Research Foundation, Of Office Of Technology Commercialization Purdue University Shape retaining gel compositions
CA2321117C (en) * 1998-02-27 2014-07-15 Purdue Research Foundation Submucosa gel compositions
US6933326B1 (en) * 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
AU2002300448B2 (en) * 1998-06-19 2005-07-28 Lifecell Corporation Particulate Acellular Tissue Matrix
DE69941216D1 (de) * 1998-06-19 2009-09-17 Lifecell Corp Teilchenförmige zellfreie gewebematrix
AU5085099A (en) 1998-06-25 2000-01-10 Penn State Research Foundation, The Electrostatic printing of a metallic toner to produce a polycrystalline semiconductor from an amorphous semiconductor
US6458109B1 (en) * 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
DK1051116T3 (da) * 1998-12-01 2009-02-02 Univ Washington Emboliseringsanordning
US8882850B2 (en) * 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
GB2360948B (en) * 1998-12-01 2003-12-10 Purdue Research Foundation Composition suitable for vocal cord reconstruction
CA2352785A1 (en) * 1998-12-01 2000-06-08 Dennis Metzger Submucosa modulation of mammalian immune response
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
EP1051206B1 (en) 1998-12-01 2008-08-20 Cook Biotech, Inc. A multi-formed collagenous biomaterial medical device
CA2378618C (en) * 1999-08-06 2009-10-06 Cook Biotech Incorporated Tubular graft construct
US6555374B1 (en) * 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
ATE422908T1 (de) 1999-12-22 2009-03-15 Acell Inc Zusammensetzung zur geweberegeneration
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US6576265B1 (en) * 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US20040043006A1 (en) * 2002-08-27 2004-03-04 Badylak Stephen F. Tissue regenerative composition
ATE390152T1 (de) 2000-04-28 2008-04-15 Baylor College Medicine Dezellularisierte gefässprothesen
US7910791B2 (en) * 2000-05-22 2011-03-22 Coffey Arthur C Combination SIS and vacuum bandage and method
US6435190B1 (en) * 2000-06-14 2002-08-20 Syde A. Taheri Autogenous cell patch cardio myoplasty and advanced muscle graft implantation system
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US6902564B2 (en) * 2001-08-15 2005-06-07 Roy E. Morgan Methods and devices for electrosurgery
US20040167244A1 (en) * 2000-08-18 2004-08-26 Auge Wayne K. Methods and compositions for fusing bone during endoscopy procedures
US6547794B2 (en) 2000-08-18 2003-04-15 Auge', Ii Wayne K. Method for fusing bone during endoscopy procedures
US7819861B2 (en) * 2001-05-26 2010-10-26 Nuortho Surgical, Inc. Methods for electrosurgical electrolysis
US7771422B2 (en) 2002-06-06 2010-08-10 Nuortho Surgical, Inc. Methods and devices for electrosurgery
US7445619B2 (en) * 2000-08-18 2008-11-04 Map Technologies Llc Devices for electrosurgery
US6685681B2 (en) * 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6855135B2 (en) * 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US20020091444A1 (en) * 2001-01-05 2002-07-11 Jun Yang Vascular tissue composition
US7066932B1 (en) 2001-05-26 2006-06-27 Map Technologies Llc Biologically enhanced irrigants
US20070038244A1 (en) * 2001-06-08 2007-02-15 Morris Edward J Method and apparatus for sealing access
US20060004408A1 (en) * 2001-06-08 2006-01-05 Morris Edward J Method and apparatus for sealing access
AU2002310364B2 (en) 2001-06-08 2006-02-23 Morris Innovative Research, Inc. Method and apparatus for sealing access
US7993365B2 (en) 2001-06-08 2011-08-09 Morris Innovative, Inc. Method and apparatus for sealing access
JP4426285B2 (ja) * 2001-06-28 2010-03-03 クック・バイオテック・インコーポレーテッド 腎被膜コラーゲンを含有する移植片プロテーゼ用具
US20030033021A1 (en) * 2001-07-16 2003-02-13 Plouhar Pamela Lynn Cartilage repair and regeneration scaffold and method
EP1416879A4 (en) * 2001-07-16 2007-04-25 Depuy Products Inc UNITARY SURGICAL DEVICE AND METHOD
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US8337537B2 (en) 2001-07-16 2012-12-25 Depuy Products, Inc. Device from naturally occurring biologically derived materials
JP4197159B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 混成の生物学的合成の生体吸収性支持骨格材料
EP1416888A4 (en) * 2001-07-16 2007-04-25 Depuy Products Inc DEVICE AND METHOD FOR REGENERATING THE MENISCUS
AU2002354915B8 (en) * 2001-07-16 2008-04-17 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
ATE499908T1 (de) 2001-07-16 2011-03-15 Depuy Products Inc Gerät zur reparatur von knorpelmaterial
WO2003007790A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
US8591508B2 (en) * 2001-08-15 2013-11-26 Nuortho Surgical, Inc. Electrosurgical plenum
US8734441B2 (en) * 2001-08-15 2014-05-27 Nuortho Surgical, Inc. Interfacing media manipulation with non-ablation radiofrequency energy system and method
US8235979B2 (en) 2001-08-15 2012-08-07 Nuortho Surgical, Inc. Interfacing media manipulation with non-ablation radiofrequency energy system and method
WO2003030966A1 (en) * 2001-10-11 2003-04-17 Hill-Rom Services, Inc. Waste container for negative pressure therapy
DE60225824T2 (de) * 2001-10-26 2009-04-16 Cook Biotech, Inc., West Lafayette Medizinisches implantat mit netzartiger struktur
US7318833B2 (en) * 2001-12-19 2008-01-15 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US7867250B2 (en) * 2001-12-19 2011-01-11 Nmt Medical, Inc. Septal occluder and associated methods
WO2003057070A2 (en) * 2001-12-26 2003-07-17 Hill-Rom Services Inc. Vented vacuum bandage and method
AU2002359830A1 (en) * 2001-12-26 2003-07-24 Hill-Rom Services, Inc. Wound vacuum therapy dressing kit
ATE387919T1 (de) * 2001-12-26 2008-03-15 Hill Rom Services Inc Vakuumbindenverpackung
WO2003059061A1 (en) 2002-01-11 2003-07-24 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
JP2005525843A (ja) * 2002-01-14 2005-09-02 エヌエムティー メディカル インコーポレイテッド 卵円孔開存（ｐｆｏ）閉塞方法および器具
WO2003082076A2 (en) * 2002-03-25 2003-10-09 Nmt Medical, Inc. Patent foramen ovale (pfo) closure clips
CA2481016C (en) 2002-04-10 2012-04-03 Hill-Rom Services, Inc. Access openings in vacuum bandage
EP1503789A4 (en) * 2002-05-02 2006-08-02 Purdue Research Foundation IMPROVED VASCULARIZATION BY GRAFT CONSTRUCTIONS
EP1503652A4 (en) 2002-05-02 2006-02-08 Purdue Research Foundation HYBRID GRAFTS WITH IMPROVED VASCULARIZATION
US20040098042A1 (en) * 2002-06-03 2004-05-20 Devellian Carol A. Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
AU2003240549A1 (en) * 2002-06-05 2003-12-22 Nmt Medical, Inc. Patent foramen ovale (pfo) closure device with radial and circumferential support
US7160326B2 (en) * 2002-06-27 2007-01-09 Depuy Products, Inc. Method and apparatus for implantation of soft tissue implant
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US20040034418A1 (en) * 2002-07-23 2004-02-19 Shu-Tung Li Membrane-reinforced implants
US7550004B2 (en) * 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
CA2495385A1 (en) 2002-08-21 2004-03-04 Hill-Rom Services, Inc. Wound packing for preventing wound closure
US7766820B2 (en) 2002-10-25 2010-08-03 Nmt Medical, Inc. Expandable sheath tubing
CA2503349A1 (en) * 2002-11-06 2004-05-27 Nmt Medical, Inc. Medical devices utilizing modified shape memory alloy
AU2003287689A1 (en) * 2002-11-07 2004-06-03 Nmt Medical, Inc. Patent foramen ovale (pfo) closure with magnetic force
US7627373B2 (en) * 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US20040187877A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
US20040191226A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
EP2399526B1 (en) * 2002-12-09 2014-11-26 W.L. Gore & Associates, Inc. Septal closure devices
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US7658747B2 (en) * 2003-03-12 2010-02-09 Nmt Medical, Inc. Medical device for manipulation of a medical implant
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20090291112A1 (en) * 2003-05-16 2009-11-26 Truncale Katherine G Allograft osteochondral plug combined with cartilage particle mixture
US7488348B2 (en) * 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
AU2004253508A1 (en) 2003-06-25 2005-01-13 Acell, Inc. Conditioned matrix compositions for tissue restoration
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
EP2481356B1 (en) * 2003-07-14 2013-09-11 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US8480706B2 (en) * 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US7153324B2 (en) * 2003-07-31 2006-12-26 Cook Incorporated Prosthetic valve devices and methods of making such devices
WO2005018728A2 (en) * 2003-08-19 2005-03-03 Nmt Medical, Inc. Expandable sheath tubing
GB2424586B (en) 2003-08-25 2008-05-28 Cook Biotech Inc Graft materials containing bioactive substances, and methods for their manufacture
US8741352B2 (en) * 2003-08-25 2014-06-03 Cook Biotech Incorporated Graft materials containing ECM components, and methods for their manufacture
GB2423934B (en) * 2003-09-04 2007-11-28 Cook Biotech Inc Extracellular matrix composite materials, and manufacture and use thereof
US20050054099A1 (en) * 2003-09-04 2005-03-10 Cedars Sinai Medical Center Matrix derived from whole organ
US7645229B2 (en) * 2003-09-26 2010-01-12 Armstrong David N Instrument and method for endoscopic visualization and treatment of anorectal fistula
US7657312B2 (en) * 2003-11-03 2010-02-02 Cardiac Pacemakers, Inc. Multi-site ventricular pacing therapy with parasympathetic stimulation
US6976679B2 (en) * 2003-11-07 2005-12-20 The Boeing Company Inter-fluid seal assembly and method therefor
US20050273119A1 (en) 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
EP2335650B1 (en) 2003-12-11 2012-10-03 Isto Technologies Inc. Particulate cartilage system
EP2193749B1 (en) 2004-01-21 2017-03-01 Cook Medical Technologies LLC Implantable graft to close a fistula
US8262694B2 (en) * 2004-01-30 2012-09-11 W.L. Gore & Associates, Inc. Devices, systems, and methods for closure of cardiac openings
US8337545B2 (en) 2004-02-09 2012-12-25 Cook Medical Technologies Llc Woven implantable device
AU2005212334B2 (en) * 2004-02-09 2011-06-16 Cook Medical Technologies Llc Stent graft devices having collagen coating
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
CA2558247A1 (en) 2004-03-03 2005-10-06 Nmt Medical, Inc. Delivery/recovery system for septal occluder
US7449027B2 (en) * 2004-03-29 2008-11-11 Cook Incorporated Modifying fluid flow in a body vessel lumen to promote intraluminal flow-sensitive processes
US20050234509A1 (en) * 2004-03-30 2005-10-20 Mmt Medical, Inc. Center joints for PFO occluders
US7244444B2 (en) * 2004-03-31 2007-07-17 Cook Incorporated Graft material, stent graft and method
AU2005231781A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated ECM-based graft material
US8216299B2 (en) * 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US20050267524A1 (en) * 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
US8361110B2 (en) * 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US8308760B2 (en) 2004-05-06 2012-11-13 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US7842053B2 (en) * 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
US7704268B2 (en) * 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
EP1748732A1 (en) 2004-05-07 2007-02-07 NMT Medical, Inc. Catching mechanisms for tubular septal occluder
WO2005115275A1 (en) * 2004-05-20 2005-12-08 Cook Incorporated Endoluminal device with extracellular matrix material and methods
WO2005118019A1 (en) * 2004-05-28 2005-12-15 Cook Incorporated Implantable bioabsorbable valve support frame
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
WO2006014592A1 (en) * 2004-07-07 2006-02-09 Cook Incorporated Graft, stent graft and method for manufacture
CA2575240A1 (en) * 2004-07-30 2006-02-09 Cook Biotech Incorporated Graft with increased resistance to enzymatic degradation
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US8764848B2 (en) * 2004-09-24 2014-07-01 W.L. Gore & Associates, Inc. Occluder device double securement system for delivery/recovery of such occluder device
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7442206B2 (en) * 2004-10-28 2008-10-28 Cook Incorporated Methods and systems for modifying vascular valves
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7387604B2 (en) * 2004-11-03 2008-06-17 Cook Incorporated Methods for treating valve-associated regions of vascular vessels
US7905826B2 (en) * 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
US8329202B2 (en) * 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
WO2006062862A1 (en) * 2004-12-06 2006-06-15 Cook Incorporated Inflatable occlusion devices, methods, and systems
WO2006062976A2 (en) * 2004-12-07 2006-06-15 Cook Incorporated Methods for modifying vascular vessel walls
US8874204B2 (en) * 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) * 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
EP1833384B1 (en) * 2004-12-30 2017-08-16 Cook Medical Technologies LLC Inverting occlusion devices and systems
US8128680B2 (en) 2005-01-10 2012-03-06 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20070150051A1 (en) * 2005-01-10 2007-06-28 Duke Fiduciary, Llc Vascular implants and methods of fabricating the same
US8287583B2 (en) * 2005-01-10 2012-10-16 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US20060246033A1 (en) * 2005-03-02 2006-11-02 Cook Biotech Incorporated Injectable bulking agent compositions
US9138445B2 (en) * 2005-03-09 2015-09-22 Cook Biotech Incorporated Medical graft materials with adherent extracellular matrix fibrous mass
US7840266B2 (en) * 2005-03-11 2010-11-23 Cardiac Pacemakers, Inc. Integrated lead for applying cardiac resynchronization therapy and neural stimulation therapy
EP1863564B1 (en) 2005-03-11 2016-11-23 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US7587238B2 (en) * 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US8277480B2 (en) 2005-03-18 2012-10-02 W.L. Gore & Associates, Inc. Catch member for PFO occluder
EP1863545B1 (en) * 2005-03-19 2015-11-18 Cook Biotech, Inc. Prosthetic implants including ECM composite material
US8197534B2 (en) * 2005-03-31 2012-06-12 Cook Medical Technologies Llc Valve device with inflatable chamber
US20060229670A1 (en) * 2005-04-01 2006-10-12 Bates Brian L Method and a medical closure system for sealing a puncture
WO2007011443A2 (en) * 2005-04-29 2007-01-25 Cook Biotech Incorporated Fistula graft with deformable sheet-form material
WO2006119256A2 (en) 2005-04-29 2006-11-09 Cook Biotech Incorporated Volumetric grafts for treatment of fistulae and related methods and systems
US20060251702A1 (en) * 2005-05-05 2006-11-09 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
CA2608708C (en) * 2005-05-16 2014-04-22 Purdue Research Foundation Engineered extracellular matrix having a specified fibril area fraction
EP1903947B1 (en) * 2005-06-21 2015-12-30 Cook Medical Technologies LLC Implantable graft to close a fistula
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
US20060293760A1 (en) * 2005-06-24 2006-12-28 Dedeyne Patrick G Soft tissue implants with improved interfaces
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US9072816B2 (en) * 2006-01-18 2015-07-07 Cormatrix Cardiovascular, Inc. Composition for modulating inflammation of cardiovascular tissue
WO2007011644A2 (en) * 2005-07-15 2007-01-25 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent tissue
US20080279939A1 (en) * 2007-05-10 2008-11-13 Firestone Leigh H Extracellular matrix compositions for tissue regeneration
US8568761B2 (en) * 2005-07-15 2013-10-29 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent myocardium
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
EP1928512B1 (en) * 2005-09-01 2012-11-14 Cook Medical Technologies LLC Attachment of material to an implantable frame by cross-linking
WO2007030433A2 (en) * 2005-09-06 2007-03-15 Nmt Medical, Inc. Removable intracardiac rf device
US9259267B2 (en) 2005-09-06 2016-02-16 W.L. Gore & Associates, Inc. Devices and methods for treating cardiac tissue
US8921109B2 (en) 2005-09-19 2014-12-30 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070088388A1 (en) * 2005-09-19 2007-04-19 Opolski Steven W Delivery device for implant with dual attachment sites
US20070082021A1 (en) * 2005-09-30 2007-04-12 Bates Brian L Coated vaso-occlusion device
CA2627285A1 (en) * 2005-10-24 2007-10-25 Nmt Medical, Inc. Radiopaque bioabsorbable occluder
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9308252B2 (en) * 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US20070112360A1 (en) * 2005-11-15 2007-05-17 Patrick De Deyne Bioprosthetic device
EP1956986B1 (en) * 2005-12-02 2017-03-29 Cook Medical Technologies LLC Devices, systems, and methods for occluding a defect
EP1962695A1 (en) * 2005-12-22 2008-09-03 NMT Medical, Inc. Catch members for occluder devices
WO2007081530A2 (en) * 2006-01-03 2007-07-19 Med Institute, Inc. Endoluminal medical device for local delivery of cathepsin inhibitors
AU2007208243B2 (en) 2006-01-25 2013-09-19 Children's Medical Center Corporation Methods and procedures for ligament repair
GB2447400B (en) * 2006-01-31 2011-11-02 Cook Biotech Inc Fistula grafts and related methods and systems for treating fistulae
US8211168B2 (en) * 2006-02-21 2012-07-03 Cook Biotech Incorporated Graft material, stent graft and method
US20070196380A1 (en) * 2006-02-22 2007-08-23 Leigh H. Firestone Extracellular matrix to treat malignancy in mammals
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
EP2004068B1 (en) * 2006-03-31 2018-08-15 W.L. Gore & Associates, Inc. Deformable flap catch mechanism for occluder device
WO2007136634A1 (en) 2006-05-16 2007-11-29 Purdue Research Foundation Three dimensional purified collagen matrices
US20070269476A1 (en) * 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
US8974542B2 (en) * 2006-06-27 2015-03-10 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
WO2008008266A2 (en) * 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
WO2008024920A1 (en) * 2006-08-24 2008-02-28 Wilson-Cook Medical Inc. Devices and methods for occluding a fistula
US20080063627A1 (en) * 2006-09-12 2008-03-13 Surmodics, Inc. Tissue graft materials containing biocompatible agent and methods of making and using same
GB2455041B (en) * 2006-09-21 2012-03-07 Purdue Research Foundation Collagen preparation and method of isolation
JP2010509943A (ja) 2006-09-28 2010-04-02 チルドレンズ メディカル センター コーポレーション 組織を修復する方法およびそのためのコラーゲン生成物
US20080082083A1 (en) * 2006-09-28 2008-04-03 Forde Sean T Perforated expandable implant recovery sheath
CA2667214C (en) 2006-10-23 2015-12-01 Cook Biotech Incorporated Processed ecm materials with enhanced component profiles
US8790414B2 (en) 2006-11-10 2014-07-29 Cook Biotech Incorporated Graft for hysterotomy closure
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US20080154233A1 (en) * 2006-12-20 2008-06-26 Zimmer Orthobiologics, Inc. Apparatus for delivering a biocompatible material to a surgical site and method of using same
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
EP2114303A4 (en) 2007-02-09 2012-08-08 Taheri Laduca Llc VASCULAR IMPLANTS AND METHODS OF MAKING SAID IMPLANTS
JP5662683B2 (ja) * 2007-02-09 2015-02-04 タヘリ ラドュカ エルエルシー 体内に植込型デバイスを展開する装置および方法
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US8435551B2 (en) * 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US9005242B2 (en) 2007-04-05 2015-04-14 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
WO2008124361A2 (en) * 2007-04-06 2008-10-16 Cook Biotech Incorporated Fistula plugs having increased column strength and fistula plug delivery apparatuses and methods
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
WO2008131167A1 (en) 2007-04-18 2008-10-30 Nmt Medical, Inc. Flexible catheter system
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
US9283302B2 (en) 2011-12-16 2016-03-15 Cormatrix Cardiovascular, Inc. Extracellular matrix encasement structures and methods
US8535349B2 (en) * 2007-07-02 2013-09-17 Cook Biotech Incorporated Fistula grafts having a deflectable graft body portion
US20090024106A1 (en) * 2007-07-17 2009-01-22 Morris Edward J Method and apparatus for maintaining access
US9113851B2 (en) 2007-08-23 2015-08-25 Cook Biotech Incorporated Fistula plugs and apparatuses and methods for fistula plug delivery
US20090062839A1 (en) * 2007-08-31 2009-03-05 Cook Incorporated Barbed stent vascular occlusion device
US8292907B2 (en) * 2007-08-31 2012-10-23 Cook Medical Technologies Llc Balloon assisted occlusion device
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
EP2187983B1 (en) * 2007-09-12 2014-04-16 Cook Incorporated Enhanced remodelable materials for occluding bodily vessels
US20090082816A1 (en) 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
US7846199B2 (en) * 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
EP2224884A2 (en) * 2007-12-05 2010-09-08 Musculoskeletal Transplant Foundation Cancellous bone implant for cartilage repair
GB2468102B (en) * 2007-12-10 2012-12-05 Purdue Research Foundation Collagen-based matrices with stem cells
US20090171406A1 (en) * 2007-12-12 2009-07-02 Cardiac Pacemakers, Inc. Electrically conducting scaffolds for cell-based pacing
US20090157170A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Trileaflet Semi-Lunar Prosthetic Tissue Valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US20090157177A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Sewing Ring for a Prosthetic Tissue Valve
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
WO2009086499A2 (en) * 2007-12-28 2009-07-09 Cook Biotech Incorporated Medical composition including an extracellular matrix particulate
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
EP2259809B1 (en) * 2008-02-29 2016-05-25 Cook Biotech Incorporated Coated embolization device
CA2717725A1 (en) * 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
WO2009146369A1 (en) * 2008-05-29 2009-12-03 Cook Biotech Incorporated Devices and methods for treating rectovaginal and other fistulae
US9295757B2 (en) 2008-06-10 2016-03-29 Cook Biotech Incorporated Quilted implantable graft
WO2009155236A1 (en) 2008-06-16 2009-12-23 Morris Innovative Research, Inc. Method and apparatus for sealing access
CA2735173C (en) 2008-09-02 2017-01-10 Tautona Group Lp Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US7927414B2 (en) * 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
US8858698B2 (en) 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
WO2010078478A1 (en) 2008-12-31 2010-07-08 Cook Biotech Incorporated Tissue adjuvants and medical products including the same
US8469779B1 (en) 2009-01-02 2013-06-25 Lifecell Corporation Method for debristling animal skin
US20100274362A1 (en) * 2009-01-15 2010-10-28 Avner Yayon Cartilage particle tissue mixtures optionally combined with a cancellous construct
WO2010088678A2 (en) 2009-02-02 2010-08-05 Cook Biotech Incorporated Medical bead products
MX2011008735A (es) * 2009-02-18 2012-01-12 Cormatrix Cardiovascular Inc Composiciones y metodos para prevenir la arritmia cardiaca.
US9205177B2 (en) * 2009-03-04 2015-12-08 Peytant Solutions, Inc. Stents modified with material comprising amnion tissue and corresponding processes
EP2427141B1 (en) 2009-05-06 2022-08-10 Hansa Medical Products, Inc. Self-adjusting medical device
US9532827B2 (en) 2009-06-17 2017-01-03 Nuortho Surgical Inc. Connection of a bipolar electrosurgical hand piece to a monopolar output of an electrosurgical generator
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
US9636094B2 (en) 2009-06-22 2017-05-02 W. L. Gore & Associates, Inc. Sealing device and delivery system
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
US9901659B2 (en) 2010-05-27 2018-02-27 University of Pittsburgh—of the Commonwealth System of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
EP3888714A1 (en) 2010-07-31 2021-10-06 Cook Medical Technologies LLC Collagenous tissue pocket for an implantable medical device, and manufacturing method therefor
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
WO2012027514A2 (en) 2010-08-24 2012-03-01 The Regents Of The University Of California Compositions and methods for cardiac therapy
US9408658B2 (en) 2011-02-24 2016-08-09 Nuortho Surgical, Inc. System and method for a physiochemical scalpel to eliminate biologic tissue over-resection and induce tissue healing
WO2012142419A1 (en) 2011-04-14 2012-10-18 Lifecell Corporation Regenerative materials
AU2012262554B2 (en) 2011-05-27 2016-09-15 Cormatrix Cardiovascular, Inc. Extracellular matrix material conduits and methods of making and using same
JP2014519906A (ja) 2011-05-27 2014-08-21 コーマトリックス カーディオバスキュラー， インコーポレイテッド 滅菌された無細胞の細胞外マトリックス組成物及びその作製方法
US9427233B2 (en) 2011-06-06 2016-08-30 Cook Medical Technologies, LLC Vascular occlusion devices and methods
US9089523B2 (en) 2011-07-28 2015-07-28 Lifecell Corporation Natural tissue scaffolds as tissue fillers
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
WO2013036708A2 (en) 2011-09-07 2013-03-14 The Regents Of The University Of California Compositions and methods for tissue repair with extracellular matrices
WO2013071096A1 (en) 2011-11-09 2013-05-16 The General Hospital Corporation Composite tissue graft and materials and methods for its production and use
US9549805B2 (en) 2011-12-20 2017-01-24 Lifecell Corporation Flowable tissue products
ES2864104T3 (es) 2011-12-20 2021-10-13 Lifecell Corp Productos tisulares laminados
DK2806907T3 (da) 2012-01-24 2019-02-18 Lifecell Corp Langstrakte vævsmatrix
EP2809340B1 (en) 2012-02-01 2021-11-24 Children's Medical Center Corporation Biomaterial for articular cartilage maintenance and treatment of arthritis
US10940167B2 (en) 2012-02-10 2021-03-09 Cvdevices, Llc Methods and uses of biological tissues for various stent and other medical applications
US9504458B2 (en) 2012-02-17 2016-11-29 Cook Biotech Incorporated Methods and systems for treating complex fistulae
US9782436B2 (en) 2012-04-24 2017-10-10 Lifecell Corporation Flowable tissue matrices
BR112015000547B1 (pt) 2012-07-13 2020-11-10 Lifecell Corporation método para tratar tecido
AU2013323747B2 (en) 2012-09-26 2017-02-02 Lifecell Corporation Processed adipose tissue
US9579142B1 (en) 2012-12-13 2017-02-28 Nuortho Surgical Inc. Multi-function RF-probe with dual electrode positioning
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
EP2951193A4 (en) 2013-02-01 2017-03-01 Children's Medical Center Corporation Collagen scaffolds
ES2781578T3 (es) 2013-02-06 2020-09-03 Lifecell Corp Métodos para la modificación localizada de productos tisulares
EP4215163A1 (en) 2013-02-11 2023-07-26 Cook Medical Technologies LLC Expandable support frame and medical device
HUE042704T2 (hu) * 2013-04-08 2019-07-29 Regentys Corp Eljárás és készítmény gyulladásos bélbetegség kezelésére kolektómia nélkül
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
AU2015231110B2 (en) 2014-03-21 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US11919941B2 (en) 2015-04-21 2024-03-05 Purdue Research Foundation Cell-collagen-silica composites and methods of making and using the same
EP3337524B1 (en) 2015-08-21 2021-03-10 Cormatrix Cardiovascular, Inc. Extracellular matrix prostheses for treating damaged biological tissue
US10173027B2 (en) 2015-10-07 2019-01-08 Cook Medical Technologies Llc Methods, medical devices and kits for modifying the luminal profile of a body vessel
AU2017235321A1 (en) 2016-03-14 2018-11-01 Regentys Corporation Method and composition for treating inflammatory Bowel Disease
EP3463500A1 (en) 2016-06-03 2019-04-10 LifeCell Corporation Methods for localized modification of tissue products
RU2627844C1 (ru) * 2016-10-24 2017-08-14 Общество С Ограниченной Ответственностью "Ниармедик Плюс" Способ получения суспензионной формы измельченного децеллюляризованного внеклеточного матрикса
EP3558405A1 (en) 2016-12-22 2019-10-30 LifeCell Corporation Devices and methods for tissue cryomilling
CA3052489A1 (en) 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ecm hydrogel for treating esophageal inflammation
ES2931299T3 (es) 2017-03-02 2022-12-28 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel de matriz extracelular (ECM) y fracción soluble del mismo para su utilización en el tratamiento del cáncer
WO2018200750A1 (en) 2017-04-25 2018-11-01 Purdue Research Foundation 3-dimensional (3d) tissue-engineered muscle for tissue restoration
AU2018351051A1 (en) 2017-10-18 2020-03-19 Lifecell Corporation Adipose tissue products and methods of production
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
ES2960617T3 (es) 2017-10-19 2024-03-05 Lifecell Corp Productos de matriz de tejido acelular fluida y métodos de producción
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
BR112021024043A2 (pt) 2019-05-30 2022-02-08 Lifecell Corp Implante mamário biológico
US20230135760A1 (en) 2020-03-16 2023-05-04 Biosearch, S.A. Biocomposites comprising probiotics, collagen and bacterial extracellular polysaccharide and uses thereof
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090558B (en) * 1981-01-06 1984-08-30 British Gas Corp Method of manufacture of a heat sealable fitting and fitting made by such method
US4502161A (en) * 1981-09-21 1985-03-05 Wall W H Prosthetic meniscus for the repair of joints
JPS624991A (ja) * 1985-06-28 1987-01-10 三菱樹脂株式会社 プラスチツク管の接合方法
JPS63272535A (ja) * 1987-05-01 1988-11-10 Nippon Denso Co Ltd 電磁誘導接着用加熱装置
US4880429A (en) * 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
JPH0739119B2 (ja) * 1988-07-11 1995-05-01 積水化学工業株式会社 溶着継手の製造方法
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US5231169A (en) * 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use

Also Published As

Publication number Publication date
CZ124095A3 (en) 1995-11-15
DE69328625D1 (de) 2000-06-15
ATE192654T1 (de) 2000-05-15
NO951881L (no) 1995-05-12
FI952337A0 (fi) 1995-05-12
FI952337A (fi) 1995-05-12
DE69328625T2 (de) 2001-02-08
RU2148379C1 (ru) 2000-05-10
PL174426B1 (pl) 1998-07-31
BR9307419A (pt) 1999-08-31
MX9307046A (es) 1995-01-31
AU5552394A (en) 1994-06-08
WO1994011008A1 (en) 1994-05-26
NZ258032A (en) 1997-05-26
NO951881D0 (no) 1995-05-12
HU9501403D0 (en) 1995-06-28
EP0671922B1 (en) 2000-05-10
PT671922E (pt) 2000-08-31
EP0671922A4 (en) 1996-08-21
GR3034144T3 (en) 2000-11-30
US5275826A (en) 1994-01-04
NZ299279A (en) 2000-08-25
SK282122B6 (sk) 2001-11-06
SK61095A3 (en) 1995-11-08
JPH08506799A (ja) 1996-07-23
HUT73965A (en) 1996-10-28
CA2149324C (en) 2005-01-18
CA2149324A1 (en) 1994-05-26
EP0671922A1 (en) 1995-09-20
JP3534408B2 (ja) 2004-06-07
US5516533A (en) 1996-05-14
ES2148309T3 (es) 2000-10-16
PL309000A1 (en) 1995-09-18
HU218891B (hu) 2000-12-28
AU677974B2 (en) 1997-05-15

Similar Documents

Publication Publication Date Title
DK0671922T3 (da) Fluidiseret intestinal submucosa og anvendelse deraf som et injicerbart vævstransplantat
ATE79544T1 (de) Zusammensetzungen zur behandlung von hypercholesterinaemie.
DE69524624T2 (de) Saponinzubereitungen und deren verwendung in iscoms
ATE293883T1 (de) Verwendung von antioxidantien zur behandlung cholestatischer lebererkrankungen
DE69232266D1 (de) Transplantat zur unterstützung von autogenem gewebewachstum
ID29393A (id) Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
ES2102154T3 (es) Inhibicion de trombina.
EE9700225A (et) Meetod diabetes mellituse raviks, kasutades KKF
UA66861C2 (uk) 2-феніл-1-[4-(2-аміноетокси)бензил]індол в комбінації з естрогенами, способи лікування та продукт для лікування
AU2740797A (en) Androstene derivatives
JP2002525043A5 (da)
NO934381L (no) Terapeutiske sammensetninger for osteoinduksjon
KR960704561A (ko) 바이러스성 유발 종양의 예방과 치료용 조성물
NO992030L (no) Terapeutiske og kosmetiske sammensetninger, deres anvendelse og fremgangsmÕte for fremstilling derav
MX9301939A (es) Composicion farmaceutica que comprende un compuesto inhibidor de 5-ó-reductasa esteroidal.
ATE69551T1 (de) Zusammensetzung zur behandlung von boesartigen tumoren insbesondere bei tieren.
SE8702527D0 (sv) Metylenderivat av androst-4-en-3,17-dioner och forfarande for deras framstellning
ES439499A1 (es) Un metodo para triturar organos de animales congelados o te-jido animal congelado.
DK272080A (da) Fr&mgangsmaade til fremstilling af 1,4-cycloalkanooxazepiner
MY107387A (en) Aromatic steroid 5-(alpha)-reductase inhibitors.
BR9507848A (pt) Composição farmcéutica contendo espiramicina eventualmente em associação com o metronizadol
Dimech et al. Somatostatin-mediated vasoconstriction in human saphenous vein
Zickmann et al. Haemodynamic effects of racemic ketamine and s (+)-ketamine
UA42614A (uk) Спосіб хірургічної профілактики епідурального фіброзу