DK0552373T3 - Apoptoseregulator - Google Patents

Apoptoseregulator

Info

Publication number
DK0552373T3
DK0552373T3 DK92914177T DK92914177T DK0552373T3 DK 0552373 T3 DK0552373 T3 DK 0552373T3 DK 92914177 T DK92914177 T DK 92914177T DK 92914177 T DK92914177 T DK 92914177T DK 0552373 T3 DK0552373 T3 DK 0552373T3
Authority
DK
Denmark
Prior art keywords
apoptosis regulator
apoptosis
regulator
Prior art date
Application number
DK92914177T
Other languages
Danish (da)
English (en)
Inventor
Satoru Nakai
Masakazu Adachi
Koutoku Aihara
Hitomi Mori
Michiaki Tominaga
Hiroyuki Ichikawa
Seiji Akamatsu
Fumio Saito
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0552373T3 publication Critical patent/DK0552373T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK92914177T 1991-07-03 1992-07-02 Apoptoseregulator DK0552373T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP16258791 1991-07-03
JP3346992 1992-02-20
JP4571892 1992-03-03
JP10058592 1992-03-25
PCT/JP1992/000841 WO1993000902A1 (fr) 1991-07-03 1992-07-02 Regulateur d'apoptose

Publications (1)

Publication Number Publication Date
DK0552373T3 true DK0552373T3 (da) 1999-12-27

Family

ID=27459795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92914177T DK0552373T3 (da) 1991-07-03 1992-07-02 Apoptoseregulator

Country Status (11)

Country Link
US (5) US5672603A (OSRAM)
EP (1) EP0552373B1 (OSRAM)
KR (1) KR100196368B1 (OSRAM)
AU (1) AU648690B2 (OSRAM)
CA (1) CA2090876A1 (OSRAM)
DE (1) DE69230131T2 (OSRAM)
DK (1) DK0552373T3 (OSRAM)
ES (1) ES2138971T3 (OSRAM)
MX (1) MX9203950A (OSRAM)
TW (1) TW229157B (OSRAM)
WO (1) WO1993000902A1 (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464833A (en) * 1992-08-19 1995-11-07 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating composition
JP3054743B2 (ja) * 1993-03-02 2000-06-19 大塚製薬株式会社 移植組織の拒絶反応抑制剤
GB9311132D0 (en) 1993-05-28 1993-07-14 Eisai London Res Lab Ltd Control of cell death
EP0674515B1 (en) * 1993-10-21 1999-09-22 Otsuka Pharmaceutical Co., Ltd. The use of carbostyril derivatives for the preparation of a medicament for the inhibition of Interleukin-8
US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
MX9603868A (es) * 1995-01-11 1997-03-29 Otsuka Pharma Co Ltd Composicion farmaceutica de derivados de indeno para la regulacion de la apoptosis.
WO1998046229A1 (en) * 1995-06-21 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Il-8 and mcaf production inhibitors
JPH0971532A (ja) * 1995-09-06 1997-03-18 Otsuka Pharmaceut Co Ltd 発癌抑制剤
US5700803A (en) * 1995-12-12 1997-12-23 Otsuka Pharmaceutical Co., Ltd. Method for reducing infarct size in subjects afflicted with ischemic heart disease
WO1998048807A1 (en) * 1997-04-25 1998-11-05 Otsuka Pharmaceutical Co., Ltd. Hyaluronate synthesis inhibitors
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
WO1999015179A1 (en) * 1997-09-25 1999-04-01 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6281191B1 (en) 1997-12-29 2001-08-28 Vladimir I. Slesarev Compositions and methods for treating hepatitis-C
FR2774289B1 (fr) * 1998-02-03 2002-05-24 Goemar Lab Sa Medicament pour le traitement des dereglements de l'apoptose
PT1520588E (pt) 1998-07-13 2015-03-31 Univ Texas Usos de anticorpos para amino fosfolípidos para o tratamento do cancro
SI1107795T1 (en) 1998-09-04 2003-06-30 The Regents Of The University Of Michigan Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis
US6277974B1 (en) 1999-12-14 2001-08-21 Cogent Neuroscience, Inc. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
EP1467767A2 (en) * 2001-12-20 2004-10-20 Cogent Neuroscience, Inc. Methods for treating conditions,disorders,or diseases involving cell death
CN101653603B (zh) 2002-07-15 2014-07-09 得克萨斯大学体系董事会 磷脂酰乙醇胺结合肽缀合物及其治疗病毒感染的用途
ATE451108T1 (de) * 2002-11-07 2009-12-15 Univ Minnesota Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
CN102018693B (zh) 2004-01-22 2013-03-13 迈阿密大学 局部辅酶q10制剂及其使用方法
EP1871385A1 (en) * 2005-02-10 2008-01-02 Regents Of The University Of Minnesota Methods for treating visual disorders
EP2136831B1 (en) 2007-03-02 2012-09-12 The Cleveland Clinic Foundation Anti-angiogenic peptides
MX2010005104A (es) 2007-11-09 2010-08-04 Peregrine Pharmaceuticals Inc Composiciones de anticuerpo anti-factor de crecimiento endotelial vascular y metodos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5430184A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative
JPS6038384B2 (ja) * 1978-03-24 1985-08-31 大塚製薬株式会社 チオセミカルバゾン誘導体
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS62135423A (ja) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd 低酸素症改善剤

Also Published As

Publication number Publication date
DE69230131D1 (de) 1999-11-18
CA2090876A1 (en) 1993-01-04
EP0552373B1 (en) 1999-10-13
AU648690B2 (en) 1994-04-28
WO1993000902A1 (fr) 1993-01-21
US5798358A (en) 1998-08-25
DE69230131T2 (de) 2000-03-02
US5872120A (en) 1999-02-16
EP0552373A4 (en) 1993-09-22
KR930702002A (ko) 1993-09-08
US5925640A (en) 1999-07-20
AU2231792A (en) 1993-02-11
KR100196368B1 (ko) 1999-06-15
US5672603A (en) 1997-09-30
HK1004469A1 (en) 1998-11-27
MX9203950A (es) 1993-05-01
EP0552373A1 (en) 1993-07-28
ES2138971T3 (es) 2000-02-01
US5916890A (en) 1999-06-29
TW229157B (OSRAM) 1994-09-01

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