DK0544907T3 - Antibakterielle penemesterderivater - Google Patents

Antibakterielle penemesterderivater

Info

Publication number
DK0544907T3
DK0544907T3 DK91914618T DK91914618T DK0544907T3 DK 0544907 T3 DK0544907 T3 DK 0544907T3 DK 91914618 T DK91914618 T DK 91914618T DK 91914618 T DK91914618 T DK 91914618T DK 0544907 T3 DK0544907 T3 DK 0544907T3
Authority
DK
Denmark
Prior art keywords
group
antibacterial
penem
penemester
derivatives
Prior art date
Application number
DK91914618T
Other languages
Danish (da)
English (en)
Inventor
Hiromitsu Iwata
Takashi Nakatsuka
Rie Tanaka
Masaji Ishiguro
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DK0544907T3 publication Critical patent/DK0544907T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/861—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrocarbon radical or a substituted hydrocarbon radical, directly attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/893—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero ring or a condensed hetero ring system, directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK91914618T 1990-08-20 1991-08-16 Antibakterielle penemesterderivater DK0544907T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21705290 1990-08-20
PCT/JP1991/001098 WO1992003442A1 (en) 1990-08-20 1991-08-16 Antibacterial penem esters derivatives

Publications (1)

Publication Number Publication Date
DK0544907T3 true DK0544907T3 (da) 2000-01-24

Family

ID=16698076

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91914618T DK0544907T3 (da) 1990-08-20 1991-08-16 Antibakterielle penemesterderivater

Country Status (23)

Country Link
US (2) US5830889A (cs)
EP (2) EP0757050B1 (cs)
JP (2) JP3148234B2 (cs)
KR (1) KR0178956B1 (cs)
AT (2) ATE186053T1 (cs)
AU (1) AU652954B2 (cs)
BR (1) BR9106789A (cs)
CA (1) CA2089368C (cs)
CZ (1) CZ282086B6 (cs)
DE (2) DE69131753T2 (cs)
DK (1) DK0544907T3 (cs)
ES (2) ES2137929T3 (cs)
FI (1) FI105186B (cs)
GR (1) GR3032372T3 (cs)
HU (1) HU213403B (cs)
IE (1) IE20000929A1 (cs)
IL (1) IL99243A (cs)
MX (1) MX9203822A (cs)
NO (1) NO302236B1 (cs)
PL (1) PL169584B1 (cs)
RU (1) RU2051919C1 (cs)
SK (1) SK280188B6 (cs)
WO (1) WO1992003442A1 (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133428C (zh) * 1998-01-13 2004-01-07 第一三得利制药株式会社 含抗生素的局部用抗菌组合物
GB9815532D0 (en) * 1998-07-17 1998-09-16 Lek Pharmaceutical & Cvhemical Pharmaceutical suspension formulation
WO2000076556A2 (en) * 1999-06-11 2000-12-21 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
WO2002062398A2 (en) 2001-01-08 2002-08-15 Neorx Corporation Radioactively labelled conjugates of phosphonates
AU2002364552A1 (en) 2001-12-13 2003-06-30 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
CN1314691C (zh) * 2005-08-22 2007-05-09 鲁南制药集团股份有限公司 法罗培南钠的制备方法
WO2007039885A1 (en) * 2005-10-05 2007-04-12 Ranbaxy Laboratories Limited A process for the preparation of faropenem
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug
CN101235044B (zh) * 2008-03-03 2010-11-03 南京华威医药科技开发有限公司 法罗培南酯的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1212105A (en) * 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
JPS6019908B2 (ja) * 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
US4654331A (en) * 1981-07-13 1987-03-31 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
US4479947A (en) * 1981-07-13 1984-10-30 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
JPS58159496A (ja) * 1983-03-02 1983-09-21 Kyoto Yakuhin Kogyo Kk セフエム系化合物
JPH075463B2 (ja) * 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
EP0275002A1 (en) * 1987-01-09 1988-07-20 Hoechst Aktiengesellschaft Process for the production of 7-oxo-4-thia-1-aza-bicyclo [3.2.0] hept-2-ene derivatives
GB8713515D0 (en) * 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
JPH026728A (ja) 1988-06-23 1990-01-10 Japan Radio Co Ltd 弾性表面波による液体粘性測定装置
GB2220203B (en) * 1988-07-04 1991-09-11 Erba Carlo Spa Process for penems
DE3839987A1 (de) * 1988-11-26 1990-05-31 Hoechst Ag Penemderivate und verfahren zu ihrer herstellung
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen

Also Published As

Publication number Publication date
DE69133273T2 (de) 2004-05-13
EP0757050A1 (en) 1997-02-05
DE69131753T2 (de) 2000-05-04
IL99243A (en) 1995-07-31
EP0757050B1 (en) 2003-06-04
HUT64349A (en) 1993-12-28
GR3032372T3 (en) 2000-04-27
FI105186B (fi) 2000-06-30
IE20000929A1 (en) 2001-05-30
US5885981A (en) 1999-03-23
HU9300461D0 (en) 1993-05-28
ATE242251T1 (de) 2003-06-15
PL169584B1 (pl) 1996-08-30
CZ282086B6 (cs) 1997-05-14
KR0178956B1 (ko) 1999-03-20
CA2089368C (en) 2002-08-06
NO930588L (no) 1993-02-19
ES2137929T3 (es) 2000-01-01
SK280188B6 (sk) 1999-09-10
CZ20993A3 (en) 1993-10-13
BR9106789A (pt) 1993-06-29
HU213403B (en) 1997-06-30
US5830889A (en) 1998-11-03
JPH06500769A (ja) 1994-01-27
WO1992003442A1 (en) 1992-03-05
EP0544907A1 (en) 1993-06-09
KR930701452A (ko) 1993-06-11
SK10793A3 (en) 1993-09-09
DE69133273D1 (de) 2003-07-10
AU652954B2 (en) 1994-09-15
EP0544907B1 (en) 1999-10-27
IL99243A0 (en) 1992-07-15
DE69131753D1 (de) 1999-12-02
MX9203822A (es) 1992-09-01
FI930682A7 (fi) 1993-02-16
NO930588D0 (no) 1993-02-19
JP2000302786A (ja) 2000-10-31
CA2089368A1 (en) 1992-02-21
RU2051919C1 (ru) 1996-01-10
FI930682A0 (fi) 1993-02-16
JP3274854B2 (ja) 2002-04-15
NO302236B1 (no) 1998-02-09
AU8333391A (en) 1992-03-17
ATE186053T1 (de) 1999-11-15
JP3148234B2 (ja) 2001-03-19
ES2198455T3 (es) 2004-02-01

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