DK0542923T3 - Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener - Google Patents

Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener

Info

Publication number
DK0542923T3
DK0542923T3 DK91918697.3T DK91918697T DK0542923T3 DK 0542923 T3 DK0542923 T3 DK 0542923T3 DK 91918697 T DK91918697 T DK 91918697T DK 0542923 T3 DK0542923 T3 DK 0542923T3
Authority
DK
Denmark
Prior art keywords
liposomes
thumus
vaccine antigens
antigen
dependent assistance
Prior art date
Application number
DK91918697.3T
Other languages
Danish (da)
English (en)
Inventor
Nathalie Garcon
Howard R Six
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Application granted granted Critical
Publication of DK0542923T3 publication Critical patent/DK0542923T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91918697.3T 1990-07-27 1991-07-24 Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener DK0542923T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55896090A 1990-07-27 1990-07-27

Publications (1)

Publication Number Publication Date
DK0542923T3 true DK0542923T3 (da) 1997-10-13

Family

ID=24231699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91918697.3T DK0542923T3 (da) 1990-07-27 1991-07-24 Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener

Country Status (22)

Country Link
US (1) US5464630A (zh)
EP (1) EP0542923B1 (zh)
JP (1) JP3518866B2 (zh)
KR (1) KR100213851B1 (zh)
CN (1) CN1032236C (zh)
AT (1) ATE157537T1 (zh)
AU (1) AU650299B2 (zh)
CA (1) CA2088163C (zh)
DE (1) DE69127545T2 (zh)
DK (1) DK0542923T3 (zh)
ES (1) ES2106088T3 (zh)
FI (1) FI107515B (zh)
GR (1) GR3025377T3 (zh)
HK (1) HK1008304A1 (zh)
IE (1) IE912535A1 (zh)
IL (1) IL98935A (zh)
NO (1) NO311167B1 (zh)
NZ (1) NZ239072A (zh)
PT (1) PT98470B (zh)
RU (1) RU2107493C1 (zh)
WO (1) WO1992002243A1 (zh)
ZA (1) ZA915755B (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879685A (en) * 1991-05-08 1999-03-09 Schweiz, Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery
WO1996007102A1 (en) * 1994-09-01 1996-03-07 Wisconsin Alumni Research Foundation Therapeutic remodeling in aids
US6060082A (en) * 1997-04-18 2000-05-09 Massachusetts Institute Of Technology Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
AUPO732997A0 (en) * 1997-06-12 1997-07-03 Csl Limited Ganglioside immunostimulating complexes and uses thereof
US5993852A (en) * 1997-08-29 1999-11-30 Pharmaderm Laboratories Ltd. Biphasic lipid vesicle composition for transdermal administration of an immunogen
US6027731A (en) * 1998-11-17 2000-02-22 Wisconsin Alumni Research Foundation Pertussis toxin induced lymphocytosis
CN102294023A (zh) * 2001-07-26 2011-12-28 奥塔戈创新公司 抗原组合物
WO2007039584A1 (en) 2005-09-30 2007-04-12 Lipoxen Technologies Limited Multivalent liposomal vaccine compositions comprising polysaccharide antigens and a protein adjuvant
RU2480479C1 (ru) * 2011-11-01 2013-04-27 Елена Викторовна Свирщевская Гетерологичный пептидный мини-антиген в составе полимерной частицы для создания противоаллергенной вакцины
CA2860599C (en) 2012-01-03 2021-07-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Native and agonist ctl epitopes of the muc1 tumor antigen
US10035832B2 (en) 2013-10-23 2018-07-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HLA-A24 agonist epitopes of MUC1-C oncoprotein and compositions and methods of use
EP3331554B1 (en) 2015-08-03 2022-05-11 The U.S.A. as represented by the Secretary, Department of Health and Human Services Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use
WO2018085751A1 (en) 2016-11-07 2018-05-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Development of agonist epitopes of the human papillomavirus
WO2020102404A1 (en) 2018-11-14 2020-05-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tp5, a peptide inhibitor of aberrant and hyperactive cdk5/p25 as treatment for cancer
US20230287067A1 (en) 2020-01-21 2023-09-14 The United States Of America,As Represented By The Secretary,Department Of Health And Human Services Human immunogenic epitopes of hemo and hhla2 human endogenous retroviruses (hervs)
WO2021150713A2 (en) 2020-01-21 2021-07-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human immunogenic epitopes of h, k, and e human endogenous retroviruses (hervs)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009343C3 (de) * 1970-02-27 1980-10-23 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Lysolecithinen als immunologische Adjuvantien
GB1502774A (en) * 1974-06-25 1978-03-01 Nat Res Dev Immunological preparations
US4196191A (en) * 1975-09-29 1980-04-01 Burroughs Wellcome Co. Biological preparations
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
HU184141B (en) * 1979-12-27 1984-07-30 Human Oltoanyagtermelo Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
US4673574A (en) * 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
US4761283A (en) * 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4565696A (en) * 1983-08-03 1986-01-21 The Regents Of The University Of California Production of immunogens by antigen conjugation to liposomes
US4708933A (en) * 1984-06-12 1987-11-24 Leaf Huang Immunoliposome assay-methods and products
CA1267087A (en) * 1985-02-14 1990-03-27 Nicolaas Visser Synthetic immunogen
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
US4882145A (en) * 1986-12-09 1989-11-21 Scripps Clinic And Research Foundation T cell epitopes of the hepatitis B virus nucleocapsid protein
AU626797B2 (en) * 1987-09-08 1992-08-13 Albany Medical College Immunogenic composites capable of selectively inducing antibody production, pharmaceutical compositions employing the same and method of selectively inducing antibody production

Also Published As

Publication number Publication date
IL98935A0 (en) 1992-07-15
AU8759791A (en) 1992-03-02
CN1059279A (zh) 1992-03-11
NO311167B1 (no) 2001-10-22
ES2106088T3 (es) 1997-11-01
IL98935A (en) 1994-01-24
EP0542923A1 (en) 1993-05-26
PT98470B (pt) 1998-02-27
IE912535A1 (en) 1992-01-29
DE69127545D1 (de) 1997-10-09
WO1992002243A1 (en) 1992-02-20
RU2107493C1 (ru) 1998-03-27
DE69127545T2 (de) 1998-01-08
CA2088163C (en) 2003-06-17
EP0542923A4 (zh) 1994-04-13
NZ239072A (en) 1997-06-24
JPH06502630A (ja) 1994-03-24
CA2088163A1 (en) 1992-01-28
GR3025377T3 (en) 1998-02-27
FI930319A (fi) 1993-01-26
NO930202D0 (no) 1993-01-21
AU650299B2 (en) 1994-06-16
ZA915755B (en) 1993-02-24
US5464630A (en) 1995-11-07
FI930319A0 (fi) 1993-01-26
PT98470A (pt) 1992-06-30
FI107515B (fi) 2001-08-31
EP0542923B1 (en) 1997-09-03
ATE157537T1 (de) 1997-09-15
JP3518866B2 (ja) 2004-04-12
NO930202L (no) 1993-01-21
CN1032236C (zh) 1996-07-10
KR100213851B1 (ko) 1999-08-02
HK1008304A1 (en) 1999-05-07

Similar Documents

Publication Publication Date Title
DK0542923T3 (da) Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener
ES2115626T3 (es) Anticuerpo monoclonal humano especifico al antigeno de superficie de la membrana de las celulas cancerosas.
DE69637481D1 (de) Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
NO177788C (no) Glykoprotein benevnt amphiregulin, samt antistoffer mot dette
AR007249A1 (es) Preparacion concentrada de anticuerpos
MY104946A (en) Antigen antibody conjugate.
ES2074062T3 (es) Inmunoensayo para antigenos hiv-1 que utilizan fragmentos de f(ab')2 como sonda.
ES2138102T3 (es) Procedimiento para la deteccion de antigeno urinario asociado a tumores.
RU93004915A (ru) Липосомы, осуществляющие тимус-зависимую помощь "слабым" антигенам, используемым для приготовления вакцины
FI935217A0 (fi) Basisk dissocieringsanalys
DK0474691T3 (da) Monoklonale antistoffer til induktion af tolerance
IT7920592A0 (it) Determinazione di antigeni oppure di anticorpi.
DE69634092D1 (de) Herstellung von antikörpern
ES2099143T3 (es) Anticuerpos monoclonales contra el alergeno de acaros y su uso.
KR890700683A (ko) 인체 면역 결핍 바이러스에 대한 항체 검색 방법
MX9203136A (es) Anticuerpos monoclonales que reconocen el antigeno 3 asociado con funcion linfocito.
ATE2048T1 (de) Isolierung von hepatitis be-antigen.
FI950248A0 (fi) Rokotteita monisoluisia loisia vastaan
DE3850993D1 (de) Monoklonaler Antikörper spezifisch gegen humane Pankreas-Phospholipase-A2.
ES2090331T3 (es) Ctaa 28a32, antigeno reconocido por mca 28a32.
FI923348A (fi) Laekemedel och foerfaranden foer kelandering av aids och aids-relaterade komplex (arc) med anvaendning av kolhydratantigener och antikroppar mot kolhydrater.
ES2059726T3 (es) Anticuerpos monoclonales que reconocen el itsp humano, hibridomas que producen los mismos, y su preparacion y uso.
IT1230673B (it) Metodo per la immunolocalizzazione di antigeni con l'impiego di anticorpi diretti contro epitopi di natura non glucidica
DE59704477D1 (de) Pharmazeutische antigen-/antikörperpräparation
NO900092L (no) Et ekspresjonssystem for fremstilling av kimeriske monoklonale antistoffer.