DK0525389T3 - Fremgangsmåde til fremstilling af mekanisk stabile, let henfaldende tabletter af formlegemer, som indeholder aktivt stof - Google Patents

Fremgangsmåde til fremstilling af mekanisk stabile, let henfaldende tabletter af formlegemer, som indeholder aktivt stof

Info

Publication number
DK0525389T3
DK0525389T3 DK92110706.6T DK92110706T DK0525389T3 DK 0525389 T3 DK0525389 T3 DK 0525389T3 DK 92110706 T DK92110706 T DK 92110706T DK 0525389 T3 DK0525389 T3 DK 0525389T3
Authority
DK
Denmark
Prior art keywords
active ingredient
lightly
molds
preparation
stable
Prior art date
Application number
DK92110706.6T
Other languages
English (en)
Inventor
Bernd Kuehn
Eberhard Prof Dr Nuernberg
Erhard Dr Seiller
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Application granted granted Critical
Publication of DK0525389T3 publication Critical patent/DK0525389T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • General Preparation And Processing Of Foods (AREA)
DK92110706.6T 1991-07-04 1992-06-25 Fremgangsmåde til fremstilling af mekanisk stabile, let henfaldende tabletter af formlegemer, som indeholder aktivt stof DK0525389T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4122217A DE4122217C2 (de) 1991-07-04 1991-07-04 Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern

Publications (1)

Publication Number Publication Date
DK0525389T3 true DK0525389T3 (da) 1996-06-17

Family

ID=6435465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92110706.6T DK0525389T3 (da) 1991-07-04 1992-06-25 Fremgangsmåde til fremstilling af mekanisk stabile, let henfaldende tabletter af formlegemer, som indeholder aktivt stof

Country Status (9)

Country Link
US (1) US5288501A (da)
EP (1) EP0525389B1 (da)
JP (1) JP3350559B2 (da)
AT (1) ATE138264T1 (da)
CA (1) CA2072933C (da)
DE (2) DE4122217C2 (da)
DK (1) DK0525389T3 (da)
ES (1) ES2087349T3 (da)
GR (1) GR3020008T3 (da)

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FR2761605B1 (fr) * 1997-04-07 2001-02-23 Prographarm Lab Forme pharmaceutique multiparticulaire, ses particules constitutives, procede et installation pour leur fabrication
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FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
WO2001064190A1 (fr) * 2000-03-01 2001-09-07 Eisai Co., Ltd. Comprimes se desagregeant rapidement contenant du poly(alcool de vinyle)
JP2002003366A (ja) * 2000-06-23 2002-01-09 Freunt Ind Co Ltd 固形薬剤用水系コーティング剤組成物
AU2002225763A1 (en) 2000-11-28 2002-06-11 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
NZ530511A (en) * 2001-07-16 2005-06-24 Astrazeneca Ab A tablet for treating disorders of the gastrointestinal tract comprising a proton pump inhibitor and at least one antacid that has a barrier layer to cover an enteric coating film
DE10347242A1 (de) 2003-10-10 2005-05-04 Wella Ag Farbstoffhaltige Pellets zum Färben von Keratinfasern
US8715724B2 (en) * 2004-10-29 2014-05-06 Mayne Pharma International Pty Ltd Tabletting process
EP1681049A1 (fr) * 2005-01-12 2006-07-19 Physica Pharma Composition pharmaceutique et forme galénique correspondante à délitement rapide en bouche, et procédé de fabrication de cette composition
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
KR100895942B1 (ko) * 2007-05-08 2009-05-07 조선대학교산학협력단 생약 추출물을 함유하는 구강 내 속붕해성 제제 조성물 및그의 제조 방법
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CN104248623B (zh) 2008-09-04 2020-04-03 安米林药品有限责任公司 使用非水性载体的持续释放制剂
EP3323423B1 (en) 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Rapid establishment and/or termination of substantial steady-state drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
BR112014025907B1 (pt) * 2012-04-18 2023-02-14 Contera Pharma Aps Formulação farmacêutica disponível para administração por via oral adequada para manejo aprimorado de transtornos do movimento
JP6392355B2 (ja) 2013-09-13 2018-09-19 アール．ピー．シェーラー テクノロジーズ、エルエルシー ペレット包含錠剤
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
MA44390A (fr) 2015-06-03 2019-01-23 Intarcia Therapeutics Inc Systèmes de mise en place et de retrait d'implant
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
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Also Published As

Publication number Publication date
ES2087349T3 (es) 1996-07-16
EP0525389A2 (de) 1993-02-03
GR3020008T3 (en) 1996-08-31
EP0525389A3 (en) 1993-12-08
DE4122217A1 (de) 1993-01-14
JPH05200099A (ja) 1993-08-10
CA2072933A1 (en) 1993-01-05
JP3350559B2 (ja) 2002-11-25
DE59206345D1 (de) 1996-06-27
US5288501A (en) 1994-02-22
CA2072933C (en) 2001-09-11
DE4122217C2 (de) 1997-02-13
ATE138264T1 (de) 1996-06-15
EP0525389B1 (de) 1996-05-22

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