DK0431535T3 - Ekstrakt af Ginkgo biloba-blade, fremgangsmåde til fremstilling deraf samt farmaceutiske produkter indeholdende ekstrakten - Google Patents

Ekstrakt af Ginkgo biloba-blade, fremgangsmåde til fremstilling deraf samt farmaceutiske produkter indeholdende ekstrakten

Info

Publication number
DK0431535T3
DK0431535T3 DK90123141.5T DK90123141T DK0431535T3 DK 0431535 T3 DK0431535 T3 DK 0431535T3 DK 90123141 T DK90123141 T DK 90123141T DK 0431535 T3 DK0431535 T3 DK 0431535T3
Authority
DK
Denmark
Prior art keywords
extract
preparation
ginkgo biloba
products containing
pharmaceutical products
Prior art date
Application number
DK90123141.5T
Other languages
Danish (da)
English (en)
Inventor
Klaus-Peter Dr Schwabe
Original Assignee
Schwabe Willmar Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwabe Willmar Gmbh & Co filed Critical Schwabe Willmar Gmbh & Co
Application granted granted Critical
Publication of DK0431535T3 publication Critical patent/DK0431535T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
DK90123141.5T 1989-12-04 1990-12-03 Ekstrakt af Ginkgo biloba-blade, fremgangsmåde til fremstilling deraf samt farmaceutiske produkter indeholdende ekstrakten DK0431535T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3940091A DE3940091A1 (de) 1989-12-04 1989-12-04 Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DK0431535T3 true DK0431535T3 (da) 1994-03-28

Family

ID=6394789

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90123141.5T DK0431535T3 (da) 1989-12-04 1990-12-03 Ekstrakt af Ginkgo biloba-blade, fremgangsmåde til fremstilling deraf samt farmaceutiske produkter indeholdende ekstrakten

Country Status (10)

Country Link
US (1) US5399348A (forum.php)
EP (1) EP0431535B1 (forum.php)
JP (1) JPH0776176B2 (forum.php)
KR (1) KR0154977B1 (forum.php)
AT (1) ATE102040T1 (forum.php)
CA (1) CA2031385C (forum.php)
DE (3) DE3940091A1 (forum.php)
DK (1) DK0431535T3 (forum.php)
ES (1) ES2024400T3 (forum.php)
GR (1) GR910300122T1 (forum.php)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
ES2036951B1 (es) * 1991-11-29 1994-01-16 Euromed S A Procedimiento de obtencion de un extracto esencialmente compuesto de ginkgoflavonoides a partir de las hojas de ginkgo biloba.
US6379714B1 (en) 1995-04-14 2002-04-30 Pharmaprint, Inc. Pharmaceutical grade botanical drugs
KR100431376B1 (ko) * 1995-06-01 2004-08-25 몬타나 리미티드 은행나무(Ginkgobiloba)잎에서의추출물
FR2738828B1 (fr) * 1995-09-20 1997-10-17 Commissariat Energie Atomique Utilisation de cyclodextrines naturelles et de leurs derives pour la solubilisation d'agents anti-agregants plaquettaires de la famille des ginkgolides
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
FR2755015B1 (fr) * 1996-10-25 1998-12-24 Sod Conseils Rech Applic Utilisation d'un extrait flavonoidique de ginkgo biloba substantiellement depourvu de terpenes, dans le domaine buccodentaire, et composition contenant un tel extrait
US6221356B1 (en) * 1996-12-13 2001-04-24 Viva America Marketing, Inc. Method of preparation of biologically active Ginkgo biloba product
US6171635B1 (en) 1997-05-06 2001-01-09 Iris G Zhao Coffee substitute
CN1290349A (zh) * 1997-10-23 2001-04-04 法玛普林特公司 药用级银杏
JP4249388B2 (ja) * 1997-11-25 2009-04-02 ファーマネックス，インコーポレイティド イチョウ抽出物の調製法
FR2771639B1 (fr) * 1997-12-03 2000-05-05 Sod Conseils Rech Applic Utilisation d'extraits de ginkgo biloba pour preparer un medicament destine a faciliter le sevrage d'individus dependants de la consommation d'une substance engendrant une dependance et/ou une addiction
DE19756848C2 (de) * 1997-12-19 2003-01-16 Schwabe Willmar Gmbh & Co Extrakte aus Blättern von Ginkgo biloba mit vermindertem Gehalt an 4'-O-Methylpyridoxin und Biflavonen
US6030621A (en) * 1998-03-19 2000-02-29 De Long; Xie Ginkgo biloba composition, method to prepare the same and uses thereof
NL1009437C2 (nl) * 1998-06-18 1999-12-21 Xenobiosis Extractiewerkwijze.
DE19829516B4 (de) * 1998-07-02 2004-08-26 Dr. Willmar Schwabe Gmbh & Co. Kg Wasserlöslicher nativer Trockenextrakt aus Gingko biloba mit hohem Gehalt an Terpenoiden und Flavonglykosiden
RU2154490C1 (ru) * 1999-07-15 2000-08-20 Кибрик Николай Давидович Способ лечения сексуальных расстройств диэнцефального генеза у мужчин
US6117431A (en) * 1999-12-03 2000-09-12 Pharmline Inc. Method for obtaining an extract from ginkgo biloba leaves
US6946283B2 (en) * 2001-01-05 2005-09-20 William Marsh Rice University Ginkgo biloba levopimaradiene synthase
US7238514B2 (en) * 2001-01-05 2007-07-03 William Marsh Rice University Diterpene-producing unicellular organism
FR2823116B1 (fr) * 2001-04-10 2004-11-19 Sod Conseils Rech Applic Procede de preparation d'une extrait de feuilles de ginkgo biloba hautement enrichi en principes actifs
US6590109B2 (en) * 2001-07-11 2003-07-08 The Trustees Of Columbia University In The City Of New York Method for isolating terpene trilactones (ginkgolides, bilobalide) from leaves and pharmaceutical powders of ginkgo biloba
FR2842425B1 (fr) * 2002-07-16 2005-04-08 Sod Conseils Rech Applic Utilisation d'extraits de ginkgo biloba pour favoriser la masse musculaire au detriment de la masse graisseuse
WO2003082185A2 (en) * 2002-03-29 2003-10-09 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof
WO2005021496A2 (en) * 2003-08-27 2005-03-10 The Trustees Of Columbia University In The City Of New York Synthesis of derivatives of ginkgolide c
US7763741B2 (en) 2003-11-12 2010-07-27 The Trustees Of Columbia University In The City Of New York Separation of ginkgolides and bilobalide from G. biloba
WO2006004386A1 (es) * 2004-07-02 2006-01-12 Rojas Castaneda Patricia Uso de un extracto del ginkgo biloba para preparar una medicina para tratar la enfermedad de parkinson
KR100623164B1 (ko) * 2004-07-22 2006-09-19 재단법인서울대학교산학협력재단 뇌신경 보호효과를 갖는 신규한 은행잎 엑스를 정제하는방법 및 이를 함유하는 조성물
WO2006083366A2 (en) * 2004-11-23 2006-08-10 The Trustees Of Columbia University In The City Of New York Preparation of ginkgolide and f-seco-ginkgolide lactols
US20060134235A1 (en) * 2004-12-22 2006-06-22 Toyo Shinyaku Co., Ltd. External preparation for improving blood flow
WO2006117170A1 (en) * 2005-05-03 2006-11-09 Dr. Willmar Schwabe Gmbh & Co. Kg Improved method for preparing ginkgo extracts having a reduced content of polycyclic aromatic hydrocarbons
DE602006002975D1 (de) * 2005-05-03 2008-11-13 Schwabe Willmar Gmbh & Co Verfahren zur herstellung eines ginkgoextrakts mit reduziertem gehalt an 4'-o-methylpyridoxin und/oder biflavonen
DE102005061948A1 (de) 2005-05-03 2006-11-16 Bioplanta Arzneimittel Gmbh Verbessertes Verfahren zur Herstellung von 4'-O-Methylpyridoxin- und/oder Biflavon-armen Ginkgoextrakten
US20090221019A1 (en) * 2005-06-22 2009-09-03 Koji Nakanishi Core-Modified Terpene Trilactones From Ginkgo Biloba Extract and Biological Evaluation Thereof
CN1954826A (zh) 2005-10-26 2007-05-02 上海生物芯片有限公司 银杏叶提取物在降低胆固醇方面的用途
HUE041715T2 (hu) 2007-12-21 2019-05-28 Dr Willmar Schwabe Gmbh & Co Kg Ginkgo biloba levél-kivonat alkalmazása
FR2926994B1 (fr) * 2008-02-06 2010-08-27 Sod Conseils Rech Applic Nouveau procede pour la preparation d'extraits de ginkgo biloba
ITMI20090548A1 (it) * 2009-04-06 2010-10-07 Indena Spa Processo di rimozione di pesticidi da estratti di ginkgo biloba e estratti ottenibili da detto processo
EP2494979B1 (de) 2011-03-04 2019-03-27 Dr. Willmar Schwabe GmbH & Co. KG Verwendung von Extrakten aus Blättern von Ginkgo biloba zur Prävention und Therapie von Komplikationen nach operativer Arteriosklerose-Behandlung sowie von Folgeerscheinungen der Arteriosklerose
MX341428B (es) 2011-04-27 2016-08-18 Dr Willmar Schwabe Gmbh & Co Kg Tableta de liberacion controlada de extracto de ginkgo biloba y procedimiento para su obtencion.
DE202011108417U1 (de) 2011-11-29 2012-03-01 Ruth-Maria Korth Örtliche und dietätische Kompositionen ohne Etherlipide, Etherphospholipide, Alkylradikale, die geeignet sind für sensible Personen
CN102491983A (zh) * 2011-12-20 2012-06-13 徐州康泰生物制品有限公司 一种制备高纯银杏内酯的方法
US10201157B2 (en) 2013-10-18 2019-02-12 Basf Agrochemical Products B.V. Use of pesticidal active carboxamide derivative in soil and seed application and treatment methods
DE102014202318B4 (de) 2014-02-10 2016-10-06 Dr. Willmar Schwabe Gmbh & Co. Kg Verbessertes Verfahren zur Herstellung von Ginkgoextrakten
CN104693214A (zh) * 2014-12-22 2015-06-10 徐州技源药业有限公司 一种银杏叶提取物中白果内酯单体的分离纯化方法
CN107846896A (zh) 2015-08-07 2018-03-27 巴斯夫欧洲公司 通过银杏内酯和白果内酯防治玉米中的害虫
CN108785335B (zh) * 2018-08-20 2024-10-25 上海上药杏灵科技药业股份有限公司 一种银杏酮酯胶囊及其制备方法
CN108785337A (zh) * 2018-08-20 2018-11-13 上海上药杏灵科技药业股份有限公司 一种银杏酮酯颗粒及其制备方法
EP3682870B1 (de) 2019-01-15 2023-08-30 Dr. Willmar Schwabe GmbH & Co. KG Verfahren zur herstellung von leicht einzunehmenden tabletten mit trockenextrakt aus ginkgo biloba blättern
DE102023131617A1 (de) * 2023-11-14 2025-05-15 Dr. Willmar Schwabe Gmbh & Co. Kg Verfahren zur Herstellung von Ginkgoextrakten mit hohem Gehalt an Proanthocyanidinen und Nahrungsergänzungsmittel und Arzneimittel enthaltend Ginkgoextrakte
FR3156652A1 (fr) 2023-12-18 2025-06-20 Beng Poon Teng Procédé de préparation d’un extrait de feuilles de ginkgo biloba hautement enrichi en proanthocyanidins depourvu de flavonoïdes et de trilactones terpéniques

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767098C2 (de) * 1968-03-29 1973-01-04 Dr. Willmar Schwabe Gmbh, 7500 Karlsruhe-Durlach Verfahren zur Gewinnung eines vasoaktiven Arzneimittels aus den Blättern von Ginkgo biloba
DE2117429C3 (de) * 1971-04-08 1982-04-01 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Verfahren zur Herstellung eines Injektions- bzw. Infusionspräparates mit einem Gehalt an einem Wirkstoffgemisch aus den Blättern von Ginkgo biloba
JPS5791932A (en) * 1980-11-28 1982-06-08 Kuraray Co Ltd Polyprenyl compound
FR2518406A1 (fr) * 1981-12-22 1983-06-24 Prodipharm Nouveau procede d'obtention de substances vaso-actives extraites de feuilles de ginkgo
US4708949A (en) * 1985-09-24 1987-11-24 Yaguang Liu Therapeutic composition from plant extracts
US4753929A (en) * 1986-03-12 1988-06-28 Daicel Chemical Industries, Ltd. Flavone glycoside
CH678150A5 (forum.php) * 1987-12-18 1991-08-15 Nuova Linnea S A
FR2627387B1 (fr) * 1988-02-24 1992-06-05 Fabre Sa Pierre Procede d'obtention d'un extrait de feuilles de ginkgo biloba
GB8822004D0 (en) * 1988-09-20 1988-10-19 Indena Spa New extracts of ginkgo biloba & their methods of preparation
DE3940094A1 (de) * 1989-12-04 1991-06-06 Montana Ltd Wirkstoffkonzentrate und neue wirkstoff-kombinationen aus blaettern von ginkgo biloba, ein verfahren zu ihrer herstellung und die wirkstoff-konzentrate bzw. die wirkstoff-kombinationen enthaltenden arzneimittel

Also Published As

Publication number Publication date
ES2024400A4 (es) 1992-03-01
DE3940091C2 (forum.php) 1991-09-19
EP0431535B1 (en) 1994-03-02
CA2031385A1 (en) 1991-06-05
ATE102040T1 (de) 1994-03-15
US5399348A (en) 1995-03-21
JPH03279331A (ja) 1991-12-10
DE69007035D1 (de) 1994-04-07
EP0431535A1 (en) 1991-06-12
JPH0776176B2 (ja) 1995-08-16
DE3940091A1 (de) 1991-06-06
KR0154977B1 (ko) 1998-11-16
KR910011275A (ko) 1991-08-07
ES2024400T3 (es) 1994-04-16
DE69007035T2 (de) 1994-06-01
CA2031385C (en) 2001-09-18
GR910300122T1 (en) 1992-03-20
DE431535T1 (de) 1991-12-19

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