DEN0007892MA - - Google Patents
Info
- Publication number
- DEN0007892MA DEN0007892MA DEN0007892MA DE N0007892M A DEN0007892M A DE N0007892MA DE N0007892M A DEN0007892M A DE N0007892MA
- Authority
- DE
- Germany
- Prior art keywords
- acetals
- oxycoumarin
- bis
- aldehydes
- cho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims description 3
- 239000011261 inert gas Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 2
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000010992 reflux Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- -1 Methoxyacetaldehyde acetal Chemical class 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- DOBMPNYZJYQDGZ-UHFFFAOYSA-N dicoumarol Chemical class C1=CC=CC2=C1OC(=O)C(CC=1C(OC3=CC=CC=C3C=1O)=O)=C2O DOBMPNYZJYQDGZ-UHFFFAOYSA-N 0.000 description 2
- 229960001912 dicoumarol Drugs 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 235000003197 Byrsonima crassifolia Nutrition 0.000 description 1
- 240000001546 Byrsonima crassifolia Species 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- HIZKPJUTKKJDGA-UHFFFAOYSA-N dicumarol Natural products O=C1OC2=CC=CC=C2C(=O)C1CC1C(=O)C2=CC=CC=C2OC1=O HIZKPJUTKKJDGA-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2122643A1 (de) | 5-Chromenolester oder -äther, Verfahren zu ihrer Herstellung und Arzneipräparate | |
| CH174811A (de) | Verfahren zur Darstellung von Tropasäure-2,2-dimethyl-3-diäthylaminopropanolester. | |
| DE2914294C2 (de) | Verfahren zur Herstellung von Verbindungen mit Phosphor-Kohlenstoff-Stickstoff-Bindung | |
| DE964599C (de) | Verfahren zur Herstellung von blutgerinnungshemmenden Stoffen | |
| DEN0007892MA (enExample) | ||
| DE2335432A1 (de) | 3,4-dihydro-2h-naphthalinon-(1)5-oxy-propyl-piperazin-derivate und verfahren zu ihrer herstellung | |
| DE1227914B (de) | Verfahren zur Herstellung von 3-(1, 2-Dithia-cyclopentyl)-5-pentansaeure | |
| DE2462966C2 (de) | Derivate des 3-Amino-4-acetyl-5-methylpyrrols und diese enthaltende pharmazeutische Zubereitungen | |
| DE33497C (de) | Verfahren zur Darstellung substituirter Chinolinderivate aus Imidochloriden und Malonsäure bzgl. Acetessigestern | |
| DE1493912C (de) | 2-(Naphthyl-l)-3-furyl-beziehungsweise -3-tetrahydrofuryl-propionsäure und deren Natriumsalze sowie Verfahren zu deren Herstellung | |
| DE279012C (enExample) | ||
| DE838140C (de) | Verfahren zur Herstellung von Amiino-aryl-pyridlyl-alkanolen und ihren Estern | |
| DE633981C (de) | Verfahren zur Herstellung wohldefinierter kristalliner Nitrate des Phenylquecksilberhydroxyds | |
| DE89243C (enExample) | ||
| DE1670053A1 (de) | Verfahren zur Herstellung neuer Derivate des Morphanthridins | |
| DES0028540MA (enExample) | ||
| DE1929731C (enExample) | ||
| AT167630B (de) | Verfahren zur Herstellung von Ketonen der Vitamin A-Reihe | |
| DE2523208C3 (de) | Thienylessigsäureester, ein Verfahren zu ihrer Herstellung sowie Arzneimittel | |
| DE946445C (de) | Verfahren zur Herstellung von p-Cyclohexylphenylmethylketonen | |
| DE888692C (de) | Verfahren zur Herstellung von ª‡-Aryl-ª‰-alkoxyacrylnitrilen | |
| DE958844C (de) | Verfahren zur Herstellung von ª†-Acyl-buttersaeuren | |
| DE1468228C (de) | Substituiert? Naphthyloxyessigsauren, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel | |
| DE587428C (de) | Verfahren zur Herstellung von 1, 5, 5- und 1, 3, 5, 5-substituierten Barbitursaeuren | |
| DE668491C (de) | Verfahren zur Herstellung von Salicylacylglykolestern |