DE93112C - - Google Patents

Info

Publication number
DE93112C
DE93112C DENDAT93112D DE93112DA DE93112C DE 93112 C DE93112 C DE 93112C DE NDAT93112 D DENDAT93112 D DE NDAT93112D DE 93112D A DE93112D A DE 93112DA DE 93112 C DE93112 C DE 93112C
Authority
DE
Germany
Prior art keywords
uric acid
tetraalkyl
uric
parts
outset
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DENDAT93112D
Other languages
English (en)
Publication of DE93112C publication Critical patent/DE93112C/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/14—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with two methyl radicals in positions 1 and 3 and two methyl radicals in positions 7, 8, or 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Description

KAISERLICHES
PATENTAMT.
Die Verwandlung der Harnsäure in Tetraalkylderivate, welche bei den in dem Patent Nr. 91811 beschriebenen Beispielen in verschiedenen Phasen erreicht wird, läfst sich auch in einer einzigen Operation ausführen, wenn man von vornherein auf 1 Molecül Harnsäure etwas mehr als 4 Molecule Alkali und 4 Molecule Halogenalkyl anwendet. Bei Benutzung von Halogenmethyl entsteht dann als Hauptproduct Tetramethylharnsäure, nebenbei wird aber auch a-Trimethylharnsäure gebildet.
Beispiel: 5 Theile Harnsäure werden in 80 Theilen Kalilauge von 10 pCt. Gehalt und 80 Theilen Wasser gelöst und mit 18 Theilen Jodmethyl unter fortwährendem . Schütteln 2 Stunden auf 100 bis iio° erhitzt. Die Flüssigkeit wird dann mit Essigsäure angesäuert, zur Trockne verdampft und die Tetramethylharnsäure durch kochendes Chloroform ausgelaugt. Die Ausbeute beträgt 70 bis 80 pCt. der angewendeten Harnsäure.
In der mit Chloroform ausgekochten Masse befindet sich die a-Trimethylharnsäure als Kalisalz. Sie wird aus der wässerigen Lösung desselben durch Mineralsäuren gefällt und durch Umkrystallisiren aus heifsem Wasser gereinigt.

Claims (1)

  1. Patent-Anspruch:
    Die Darstellung der Tetraalkylharnsäuren aus Harnsäure nach dem durch das Patent Nr. 91811 geschützten Verfahren in einer einzigen Operation in der Weise, dafs die Harnsäure gleich von vornherein mit der für die Ueberführung in ihr Tetraalkylderivat erforderlichen Menge Alkali und Halogenalkyl behandelt wird.
DENDAT93112D Active DE93112C (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE93112T

Publications (1)

Publication Number Publication Date
DE93112C true DE93112C (de)

Family

ID=33035591

Family Applications (5)

Application Number Title Priority Date Filing Date
DENDAT92310D Active DE92310C (de)
DENDAT94631D Active DE94631C (de)
DENDAT111668D Active DE111668C (de)
DENDAT91811D Active DE91811C (de)
DENDAT93112D Active DE93112C (de)

Family Applications Before (4)

Application Number Title Priority Date Filing Date
DENDAT92310D Active DE92310C (de)
DENDAT94631D Active DE94631C (de)
DENDAT111668D Active DE111668C (de)
DENDAT91811D Active DE91811C (de)

Country Status (1)

Country Link
DE (5) DE93112C (de)

Also Published As

Publication number Publication date
DE91811C (de)
DE94631C (de)
DE111668C (de)
DE92310C (de)

Similar Documents

Publication Publication Date Title
DE734743C (de) Verfahren zur Herstellung von polyamidartigen Verbindungen
EP0027982B1 (de) Verfahren zur Herstellung von 3-Amino-1-hydroxypropan-1,1-diphosphonsäure
DE1793745A1 (de) Arylsubstituierte biguanide
DE93112C (de)
DE224538C (de)
CH281901A (de) Verfahren zur Herstellung eines neuen Tropasäureabkömmlings.
DE2143720C3 (de) Verfahren zur Herstellung von reinem DL-Tryptophan
DE158592C (de)
DE301871C (de)
DE209728C (de)
DE289027C (de)
DE98031C (de)
DE2065698B2 (de) Verfahren zur Herstellung von 2-Isopropyl-6-methyl-4(3H)-pyrimidon
DE203717C (de)
DE2215896C3 (de) Verfahren zur Herstellung von 5-Fluor-uracil
DE613402C (de) Verfahren zur Darstellung von 4-Pyridylpyridiniumdichlorid
AT346848B (de) Verfahren zur herstellung von 2,4-diamino-5-(2- methyl-4,5-dimethoxybenzyl)-pyrimidin
DE120772C (de)
AT117475B (de) Verfahren zur Darstellung von Substitutionsprodukten des ß-Jodpyridins.
AT235853B (de) Verfahren zur Herstellung von neuen Thiobarbitursäuren
DE57942C (de) Verfahren zur Darstellung von Aethenylnaphtylendiaminsulfosäure
DE157896C (de)
DE223796C (de)
DE1063170B (de) Verfahren zur Herstellung von 3, 5-Dioxopyrazolidinderivaten
CH251026A (de) Verfahren zur Herstellung von Nicotinsäure-B-picolylester.