DE69940427D1 - Verfahren zur isolierung von polynukleotiden aus dem mycobakteriellen genom durch verwendung einer bac-basierenden dns-bibliothek: verwendung zur erkennung - Google Patents

Verfahren zur isolierung von polynukleotiden aus dem mycobakteriellen genom durch verwendung einer bac-basierenden dns-bibliothek: verwendung zur erkennung

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Publication number
DE69940427D1
DE69940427D1 DE69940427T DE69940427T DE69940427D1 DE 69940427 D1 DE69940427 D1 DE 69940427D1 DE 69940427 T DE69940427 T DE 69940427T DE 69940427 T DE69940427 T DE 69940427T DE 69940427 D1 DE69940427 D1 DE 69940427D1
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DE
Germany
Prior art keywords
bac
detection
dna library
genome
based dna
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Expired - Lifetime
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DE69940427T
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English (en)
Inventor
Stewart Cole
Roland Buchrieser-Brosch
Stephen Gordon
Alain Billault
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Institut Pasteur de Lille
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Institut Pasteur de Lille
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DE69940427T 1998-04-16 1999-04-16 Verfahren zur isolierung von polynukleotiden aus dem mycobakteriellen genom durch verwendung einer bac-basierenden dns-bibliothek: verwendung zur erkennung Expired - Lifetime DE69940427D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/060,756 US6183957B1 (en) 1998-04-16 1998-04-16 Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria
PCT/IB1999/000740 WO1999054487A2 (en) 1998-04-16 1999-04-16 A method for isolating a polynucleotide of interest from the genome of a mycobacterium using a bac-based dna library. application to the detection of mycobacteria

Publications (1)

Publication Number Publication Date
DE69940427D1 true DE69940427D1 (de) 2009-04-02

Family

ID=22031547

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69940427T Expired - Lifetime DE69940427D1 (de) 1998-04-16 1999-04-16 Verfahren zur isolierung von polynukleotiden aus dem mycobakteriellen genom durch verwendung einer bac-basierenden dns-bibliothek: verwendung zur erkennung

Country Status (10)

Country Link
US (7) US6183957B1 (de)
EP (2) EP2058325A3 (de)
AT (1) ATE423212T1 (de)
AU (1) AU3164099A (de)
CY (1) CY1109058T1 (de)
DE (1) DE69940427D1 (de)
DK (1) DK1071797T3 (de)
ES (1) ES2322521T3 (de)
PT (1) PT1071797E (de)
WO (1) WO1999054487A2 (de)

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US6183957B1 (en) 1998-04-16 2001-02-06 Institut Pasteur Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria
FR2791067B1 (fr) 1999-03-16 2003-01-31 Pasteur Institut Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins
US7052844B2 (en) * 1999-12-21 2006-05-30 Ingeneus, Inc. Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism
CA2404988A1 (fr) * 2000-04-11 2001-10-18 Institut Pasteur Genome de listeria monocytogenes, polypeptides et utilisations
US20020137043A1 (en) * 2000-08-26 2002-09-26 Nila Patil Method for reducing complexity of nucleic acid samples
US20020164634A1 (en) * 2000-08-26 2002-11-07 Perlegen Sciences, Inc. Methods for reducing complexity of nucleic acid samples
CN1277843C (zh) 2001-02-22 2006-10-04 巴斯德研究院 分枝杆菌比较基因组学作为鉴定分枝杆菌病的诊断、预防或治疗靶的工具
CA2451026C (en) * 2001-06-22 2013-12-10 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
EP2196473A1 (de) 2001-07-04 2010-06-16 Health Protection Agency Während der Latenz exprimierten Antigene aus Mycobacterium
WO2003018053A1 (en) * 2001-08-22 2003-03-06 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccine against mycobacterial-induced diseases
US7439346B2 (en) * 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
GB0125535D0 (en) * 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
US20040023237A1 (en) * 2001-11-26 2004-02-05 Perelegen Sciences Inc. Methods for genomic analysis
US20060183132A1 (en) * 2005-02-14 2006-08-17 Perlegen Sciences, Inc. Selection probe amplification
US20090124514A1 (en) * 2003-02-26 2009-05-14 Perlegen Sciences, Inc. Selection probe amplification
US20050100911A1 (en) * 2003-08-06 2005-05-12 Perlegen Sciences, Inc. Methods for enriching populations of nucleic acid samples
ITRM20030411A1 (it) * 2003-08-29 2005-02-28 Consiglio Nazionale Ricerche Uso di sequenze geniche specifiche di mycobacterium tubercolosis ecorrispondenti proteine per la diagnosi e la prevenzione di infezione tubercolare.
EP1678329A4 (de) * 2003-10-30 2008-07-02 Tufts New England Medical Ct Pränataldiagnose unter verwendung von zellfreier fötaler dna in fruchtwasser
KR20070072608A (ko) 2004-10-22 2007-07-04 레비비코르 인코포레이션 유전자 변형된 면역계를 가지는 유제류
EP1910410B1 (de) * 2005-07-01 2011-10-26 Forsyth Dental Infirmary for Children Assays zum nachweis von tuberkulose- antigenen, und impfstoffe
CA2638904A1 (en) * 2006-01-20 2007-07-26 University Of South Florida Methods for profiling transcriptosomes
RU2341288C1 (ru) * 2007-05-10 2008-12-20 Общество С Ограниченной Ответственностью "Биотэк" СРЕДСТВО, ОБЛАДАЮЩЕЕ СВОЙСТВОМ ФОРМИРОВАТЬ КЛЕТОЧНЫЙ ИММУНИТЕТ ПРОТИВ MYCOBACTERIUM TUBERCULOSIS H37 Rv, СПОСОБ ПОЛУЧЕНИЯ ЕГО (ВАРИАНТЫ), РЕКОМБИНАНТНЫЙ ШТАММ И СРЕДСТВО ДЛЯ ДИАГНОСТИКИ ТУБЕРКУЛЕЗА
EP2348827B1 (de) 2008-10-27 2015-07-01 Revivicor, Inc. Immunsupprimierte huftiere
CN102656279A (zh) * 2009-12-17 2012-09-05 凯津公司 基于全基因组测序的限制性酶
US8865404B2 (en) * 2010-11-05 2014-10-21 President And Fellows Of Harvard College Methods for sequencing nucleic acid molecules
WO2015083056A2 (en) * 2013-12-03 2015-06-11 Kusuma School Of Biological Sciences Genetic markers for diagnosis of tuberculosis caused by mycobacterium tuberculosis

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FR2422956A1 (fr) 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
FR2518755B1 (fr) 1981-12-23 1986-04-11 Pasteur Institut Sonde contenant un acide nucleique modifie et reconnaissable par des anticorps specifiques et utilisation de cette sonde pour detecter et caracteriser une sequence d'adn homologue
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4868105A (en) 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5776693A (en) * 1990-06-08 1998-07-07 Institut Pasteur Specific detection of the mycobacterium tuberculosis
EP0554437B1 (de) * 1991-07-31 2000-04-05 VYSIS, Inc. Nukleinsäure sonden welche bei nachweis von shigellabakterien verwendbar sind
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
EP1134293A3 (de) 1992-03-04 2004-01-07 The Regents of The University of California Vergleichende Genomhybridisierung
CA2131161C (en) 1992-03-04 2004-10-26 Randy M. Berka Production of aspergillus niger catalase-r
US6641814B1 (en) * 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
NL192999C (nl) 1994-11-17 1998-07-03 Lederverwerkende Ind De Buffel Koppeling.
ATE324445T1 (de) * 1995-09-01 2006-05-15 Corixa Corp Verbindungen und verfahren zur diagnose von tuberkulose
GB9526178D0 (en) 1995-12-21 1996-02-21 Taylor John Hermon Novel polynuceotides and polypeptides in pathogenic mycobacteria and their use as diagnostics,vaccines and targets for chemotherapy
EP0907751A2 (de) * 1996-04-29 1999-04-14 Gesellschaft für Biotechnologische Forschung mbH (GBF) Dns, rns und ein protein zu erkennung einer mycobakterieninfektion
US6183957B1 (en) * 1998-04-16 2001-02-06 Institut Pasteur Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria

Also Published As

Publication number Publication date
EP2058325A3 (de) 2009-10-28
CY1109058T1 (el) 2014-07-02
EP1071797B1 (de) 2009-02-18
ES2322521T3 (es) 2009-06-22
US8455187B2 (en) 2013-06-04
WO1999054487A2 (en) 1999-10-28
WO1999054487A3 (en) 1999-12-09
US20030198974A1 (en) 2003-10-23
PT1071797E (pt) 2009-05-20
AU3164099A (en) 1999-11-08
US6183957B1 (en) 2001-02-06
US20050250104A1 (en) 2005-11-10
US6492506B1 (en) 2002-12-10
ATE423212T1 (de) 2009-03-15
US20060063182A1 (en) 2006-03-23
US7112663B1 (en) 2006-09-26
EP1071797A2 (de) 2001-01-31
US7842781B2 (en) 2010-11-30
EP2058325A2 (de) 2009-05-13
US20070092884A1 (en) 2007-04-26
US6991904B2 (en) 2006-01-31
DK1071797T3 (da) 2009-06-02

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