ATE530569T1 - Assays zum nachweis von tuberkulose- antigenen, und impfstoffe - Google Patents
Assays zum nachweis von tuberkulose- antigenen, und impfstoffeInfo
- Publication number
- ATE530569T1 ATE530569T1 AT06774367T AT06774367T ATE530569T1 AT E530569 T1 ATE530569 T1 AT E530569T1 AT 06774367 T AT06774367 T AT 06774367T AT 06774367 T AT06774367 T AT 06774367T AT E530569 T1 ATE530569 T1 AT E530569T1
- Authority
- AT
- Austria
- Prior art keywords
- antigens
- vaccines
- assay
- detection
- tuberculosis antigens
- Prior art date
Links
- 201000008827 tuberculosis Diseases 0.000 title abstract 5
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 238000003556 assay Methods 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 208000036981 active tuberculosis Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69643905P | 2005-07-01 | 2005-07-01 | |
| US71706205P | 2005-09-14 | 2005-09-14 | |
| PCT/US2006/025620 WO2007005627A2 (en) | 2005-07-01 | 2006-06-29 | Tuberculosis antigen detection assays and vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE530569T1 true ATE530569T1 (de) | 2011-11-15 |
Family
ID=37504020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06774367T ATE530569T1 (de) | 2005-07-01 | 2006-06-29 | Assays zum nachweis von tuberkulose- antigenen, und impfstoffe |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7968694B2 (de) |
| EP (2) | EP1910410B1 (de) |
| CN (1) | CN101365714A (de) |
| AT (1) | ATE530569T1 (de) |
| BR (1) | BRPI0613168A2 (de) |
| WO (1) | WO2007005627A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1144447B1 (de) * | 1998-11-04 | 2009-10-14 | Isis Innovation Limited | Tuberkulose diagnose test |
| EP2397855A3 (de) | 2006-03-14 | 2012-03-14 | Oregon Health and Science University | Methoden zur Detektion einer Mycobakterium tuberculosis Infektion |
| EP2438173A4 (de) * | 2009-06-05 | 2012-10-31 | Univ Ohio State Res Found | Biomaterialien, zusammensetzungen und verfahren |
| CN102675425B (zh) * | 2011-04-22 | 2013-12-04 | 中国医学科学院病原生物学研究所 | 一种功能性结核分枝杆菌抗原多肽及其应用 |
| CN102590502B (zh) * | 2012-01-11 | 2014-07-02 | 北京市结核病胸部肿瘤研究所 | 辅助诊断结核病患者的试剂盒 |
| WO2013112103A1 (en) * | 2012-01-27 | 2013-08-01 | Peas Institut Ab | Method of detecting tuberculosis |
| WO2015164617A1 (en) * | 2014-04-24 | 2015-10-29 | Somalogic, Inc. | Tuberculosis biomarkers in urine and uses thereof |
| CN105181837A (zh) * | 2015-08-28 | 2015-12-23 | 程永娟 | 一种结核分枝杆菌检测方法 |
| CN108267588B (zh) * | 2016-12-30 | 2020-10-23 | 首都医科大学附属北京胸科医院 | 结核分枝杆菌蛋白在制备诊断结核潜伏感染者和/或活动性肺结核产品中的用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172124A (en) | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| US4612132A (en) | 1984-07-20 | 1986-09-16 | Chevron Research Company | Modified succinimides |
| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| DE69033487T2 (de) | 1989-12-20 | 2000-06-29 | Autoimmune Inc | Behandlung von autoimmunkrankheiten durch verabreichung von autoantigenen in form von aerosol |
| NZ241954A (en) | 1991-03-15 | 1994-01-26 | Amgen Inc | Compositions of g-csf for pulmonary administration. |
| US5643873A (en) | 1992-05-06 | 1997-07-01 | Affymax Technologies N.V. | Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1 |
| ES2143716T3 (es) | 1992-06-25 | 2000-05-16 | Smithkline Beecham Biolog | Composicion de vacuna que contiene adyuvantes. |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5654276A (en) | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| US5837490A (en) | 1996-06-17 | 1998-11-17 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US6290969B1 (en) | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| US6592877B1 (en) | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6338852B1 (en) | 1995-09-01 | 2002-01-15 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| US6544522B1 (en) * | 1998-12-30 | 2003-04-08 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| US6627198B2 (en) | 1997-03-13 | 2003-09-30 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis antigens and their uses |
| US6555653B2 (en) | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
| US6613881B1 (en) | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
| GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| US6183957B1 (en) * | 1998-04-16 | 2001-02-06 | Institut Pasteur | Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria |
| US6294328B1 (en) * | 1998-06-24 | 2001-09-25 | The Institute For Genomic Research | DNA sequences for strain analysis in Mycobacterium tuberculosis |
| WO2002048175A2 (en) * | 2000-12-13 | 2002-06-20 | Argonex Pharmaceuticals | Mhc class i associated peptides for prevention and treatment of tuberculosis |
| AU2002338423A1 (en) * | 2001-04-20 | 2002-11-05 | The Regents Of The University Of California | Mycobacterial sulfation pathway proteins and methods of use thereof |
| JP2005508613A (ja) | 2001-07-04 | 2005-04-07 | ヘルス プロテクション エージェンシー | 潜伏中に発現されるマイコバクテリア抗原 |
| GB0124593D0 (en) * | 2001-10-12 | 2001-12-05 | Microbiological Res Authority | Mycobacterial antigens expressed under high oxygen tension |
| WO2003070187A2 (en) * | 2002-02-15 | 2003-08-28 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
-
2006
- 2006-06-29 AT AT06774367T patent/ATE530569T1/de not_active IP Right Cessation
- 2006-06-29 WO PCT/US2006/025620 patent/WO2007005627A2/en active Application Filing
- 2006-06-29 US US11/478,366 patent/US7968694B2/en not_active Expired - Fee Related
- 2006-06-29 CN CNA2006800269100A patent/CN101365714A/zh active Pending
- 2006-06-29 EP EP06774367A patent/EP1910410B1/de active Active
- 2006-06-29 EP EP10180752A patent/EP2305701A1/de not_active Withdrawn
- 2006-06-29 BR BRPI0613168-9A patent/BRPI0613168A2/pt not_active IP Right Cessation
-
2011
- 2011-06-21 US US13/164,962 patent/US20110268758A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110268758A1 (en) | 2011-11-03 |
| EP1910410A2 (de) | 2008-04-16 |
| US20070036816A1 (en) | 2007-02-15 |
| BRPI0613168A2 (pt) | 2010-12-21 |
| EP2305701A1 (de) | 2011-04-06 |
| WO2007005627A2 (en) | 2007-01-11 |
| WO2007005627A3 (en) | 2007-06-07 |
| US7968694B2 (en) | 2011-06-28 |
| WO2007005627A8 (en) | 2008-10-16 |
| EP1910410B1 (de) | 2011-10-26 |
| CN101365714A (zh) | 2009-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |