DE69937732D1 - Biosynthetische gene zur spinosyn-insektizidherstellung - Google Patents
Biosynthetische gene zur spinosyn-insektizidherstellungInfo
- Publication number
- DE69937732D1 DE69937732D1 DE69937732T DE69937732T DE69937732D1 DE 69937732 D1 DE69937732 D1 DE 69937732D1 DE 69937732 T DE69937732 T DE 69937732T DE 69937732 T DE69937732 T DE 69937732T DE 69937732 D1 DE69937732 D1 DE 69937732D1
- Authority
- DE
- Germany
- Prior art keywords
- manufacture
- biosynthetic genes
- spinosyn insecticide
- spinosyn
- insecticide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36987 | 1998-03-09 | ||
US09/036,987 US6143526A (en) | 1998-03-09 | 1998-03-09 | Biosynthetic genes for spinosyn insecticide production |
PCT/US1999/003212 WO1999046387A1 (en) | 1998-03-09 | 1999-02-16 | Biosynthetic genes for spinosyn insecticide production |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69937732D1 true DE69937732D1 (de) | 2008-01-24 |
DE69937732T2 DE69937732T2 (de) | 2008-12-04 |
Family
ID=21891822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69937732T Expired - Lifetime DE69937732T2 (de) | 1998-03-09 | 1999-02-16 | Biosynthetische gene zur spinosyn-insektizidherstellung |
Country Status (18)
Country | Link |
---|---|
US (4) | US6143526A (de) |
EP (1) | EP1062345B1 (de) |
JP (1) | JP2002505881A (de) |
KR (1) | KR100588436B1 (de) |
CN (1) | CN1227362C (de) |
AR (1) | AR014687A1 (de) |
AT (1) | ATE380872T1 (de) |
AU (1) | AU764737B2 (de) |
BR (1) | BR9909257B1 (de) |
CA (1) | CA2322449C (de) |
DE (1) | DE69937732T2 (de) |
ES (1) | ES2299240T3 (de) |
ID (1) | ID26862A (de) |
IL (2) | IL138241A0 (de) |
NZ (1) | NZ506624A (de) |
TW (1) | TWI237058B (de) |
WO (1) | WO1999046387A1 (de) |
ZA (1) | ZA991837B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143526A (en) * | 1998-03-09 | 2000-11-07 | Baltz; Richard H. | Biosynthetic genes for spinosyn insecticide production |
US7285653B1 (en) | 1999-08-27 | 2007-10-23 | Bayer Aktiengesellschaft | Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis |
AR033022A1 (es) | 2001-03-30 | 2003-12-03 | Dow Agrosciences Llc | Genes biosinteticos para la produccion de insecticida de butenilespinosina |
KR20100039443A (ko) * | 2001-08-06 | 2010-04-15 | 큐비스트 파마슈티컬즈 인코포레이티드 | 답토마이신 생합성 유전자 클러스터에 관련된 조성물 및 방법 |
DK1492404T3 (da) | 2002-02-19 | 2012-04-23 | Dow Agrosciences Llc | Nye spinosyndannende polyketidsyntaser |
EP1477563A3 (de) * | 2003-05-16 | 2004-11-24 | Wyeth | Klonierung von Streptomyces cyaneogriseus subsp.noncyanogenus Genen zur Biosynthese von Antibiotika und Verfahren zu ihrer Verwendung |
GB0327721D0 (en) * | 2003-11-28 | 2003-12-31 | Biotica Tech Ltd | Polyketides and their synthesis |
US8470381B2 (en) * | 2008-09-22 | 2013-06-25 | Christine Kritikou | Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms |
TW201041508A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
TW201041507A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity and methods for preparing same |
TW201041510A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
TW201041509A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
WO2010150100A1 (en) | 2009-06-24 | 2010-12-29 | Entarco Sa | The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer |
CN102191208A (zh) * | 2010-03-17 | 2011-09-21 | 上海医药工业研究院 | 高产多杀菌素的基因工程菌及其制备方法 |
KR20130080007A (ko) | 2010-05-11 | 2013-07-11 | 다우 아그로사이언시즈 엘엘씨 | Spnk 균주 |
US20160184340A1 (en) | 2010-12-22 | 2016-06-30 | Christine Kritikou | The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents |
CN103459610A (zh) | 2011-01-28 | 2013-12-18 | 阿迈瑞斯公司 | 凝胶包裹的微集落筛选 |
US9404107B2 (en) * | 2011-05-03 | 2016-08-02 | Dow Agrosciences Llc | Integration of genes into the chromosome of Saccharopolyspora spinosa |
US8741603B2 (en) * | 2011-05-03 | 2014-06-03 | Agrigenetics Inc. | Enhancing spinosyn production with oxygen binding proteins |
DK2520653T3 (en) | 2011-05-03 | 2017-07-03 | Dow Agrosciences Llc | INTEGRATION OF GENES IN THE CHROMOSOME OF SACCHAROPOLYSPORA SPINOSA |
US20140057314A1 (en) | 2011-05-13 | 2014-02-27 | Amyris, Inc. | Methods and compositions for detecting microbial production of water-immiscible compounds |
WO2013009690A2 (en) * | 2011-07-09 | 2013-01-17 | The Regents Of The University Of California | Leukemia stem cell targeting ligands and methods of use |
US9631195B2 (en) * | 2011-12-28 | 2017-04-25 | Dow Agrosciences Llc | Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa |
CN104540949B (zh) | 2012-08-07 | 2018-05-29 | 阿迈瑞斯公司 | 用于稳定乙酰-辅酶a衍生化合物生成的方法 |
CA2903053C (en) | 2013-03-15 | 2023-01-17 | Amyris, Inc. | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds |
US10563229B2 (en) | 2013-08-07 | 2020-02-18 | Amyris, Inc. | Methods for stabilizing production of acetyl-coenzyme a derived compounds |
CN103740631B (zh) * | 2013-12-31 | 2015-09-30 | 天津大学 | 能提高多杀菌素产量的基因工程菌及构建方法及应用 |
EP3219788A4 (de) * | 2014-11-14 | 2018-05-23 | Zhejiang Hisun Pharmaceutical Co., Ltd | Heterologer spinosad-expressionsstamm und konstruktionsverfahren dafür und verwendung |
US10808015B2 (en) | 2015-06-25 | 2020-10-20 | Amyris, Inc. | Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds |
AU2016317848A1 (en) | 2015-09-03 | 2018-03-15 | Agrimetis, Llc | Spinosyn derivatives as insecticides |
AU2018207051A1 (en) | 2017-01-13 | 2019-07-25 | Agrimetis, Llc | Aziridine spinosyn derivatives and methods of making |
EP3635111A1 (de) * | 2017-06-06 | 2020-04-15 | Zymergen, Inc. | Transposonmutagenese mit hohem durchsatz |
CN109096366B (zh) * | 2017-06-21 | 2021-09-10 | 中南大学 | Rgd环肽偶联亲脂性阳离子多杀菌素衍生物及其制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935340A (en) * | 1985-06-07 | 1990-06-19 | Eli Lilly And Company | Method of isolating antibiotic biosynthetic genes |
EP0463707A1 (de) * | 1985-12-17 | 1992-01-02 | Lubrizol Genetics Inc. | Herstellung von Polyketid-Antibiotika |
US5672497A (en) * | 1986-03-21 | 1997-09-30 | Eli Lilly And Company | Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms |
US4874748A (en) * | 1986-03-24 | 1989-10-17 | Abbott Laboratories | Cloning vectors for streptomyces and use thereof in macrolide antibiotic production |
US5149638A (en) * | 1988-09-29 | 1992-09-22 | Eli Lilly And Company | Tylosin biosynthetic genes tylA, tylB and tylI |
US5362634A (en) * | 1989-10-30 | 1994-11-08 | Dowelanco | Process for producing A83543 compounds |
US5252474A (en) * | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
WO1993013663A1 (en) * | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
EP0604495B1 (de) | 1991-09-18 | 1997-07-30 | Hoechst Aktiengesellschaft | Sekundärmetabolit-biosynthesegene aus aktinomyceten, verfahren zu ihrer isolierung sowie ihre verwendung |
US5591606A (en) * | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
PT725778E (pt) * | 1993-09-20 | 2002-03-28 | Univ Leland Stanford Junior | Producao recombinante de novos policetidos |
US5712146A (en) * | 1993-09-20 | 1998-01-27 | The Leland Stanford Junior University | Recombinant combinatorial genetic library for the production of novel polyketides |
US5672491A (en) * | 1993-09-20 | 1997-09-30 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
CA2197524A1 (en) * | 1996-02-22 | 1997-08-22 | Bradley Stuart Dehoff | Polyketide synthase genes |
US6143526A (en) * | 1998-03-09 | 2000-11-07 | Baltz; Richard H. | Biosynthetic genes for spinosyn insecticide production |
US7285653B1 (en) * | 1999-08-27 | 2007-10-23 | Bayer Aktiengesellschaft | Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis |
DE19957268A1 (de) * | 1999-08-27 | 2001-03-08 | Bayer Ag | Nucleinsäuren, die für Enzymaktivitäten der Spinosyn-Biosynthese kodieren |
AR033022A1 (es) * | 2001-03-30 | 2003-12-03 | Dow Agrosciences Llc | Genes biosinteticos para la produccion de insecticida de butenilespinosina |
-
1998
- 1998-03-09 US US09/036,987 patent/US6143526A/en not_active Expired - Lifetime
-
1999
- 1999-02-16 ID IDW20001725A patent/ID26862A/id unknown
- 1999-02-16 CA CA2322449A patent/CA2322449C/en not_active Expired - Lifetime
- 1999-02-16 AT AT99907034T patent/ATE380872T1/de not_active IP Right Cessation
- 1999-02-16 BR BRPI9909257-3A patent/BR9909257B1/pt not_active IP Right Cessation
- 1999-02-16 NZ NZ506624A patent/NZ506624A/en not_active IP Right Cessation
- 1999-02-16 CN CNB998051462A patent/CN1227362C/zh not_active Expired - Lifetime
- 1999-02-16 KR KR1020007009988A patent/KR100588436B1/ko active IP Right Grant
- 1999-02-16 ES ES99907034T patent/ES2299240T3/es not_active Expired - Lifetime
- 1999-02-16 EP EP99907034A patent/EP1062345B1/de not_active Expired - Lifetime
- 1999-02-16 WO PCT/US1999/003212 patent/WO1999046387A1/en active IP Right Grant
- 1999-02-16 JP JP2000535754A patent/JP2002505881A/ja active Pending
- 1999-02-16 DE DE69937732T patent/DE69937732T2/de not_active Expired - Lifetime
- 1999-02-16 IL IL13824199A patent/IL138241A0/xx active IP Right Grant
- 1999-02-16 AU AU26800/99A patent/AU764737B2/en not_active Expired
- 1999-03-08 ZA ZA9901837A patent/ZA991837B/xx unknown
- 1999-03-08 AR ARP990100978A patent/AR014687A1/es active IP Right Grant
- 1999-03-08 TW TW088103537A patent/TWI237058B/zh not_active IP Right Cessation
- 1999-08-09 US US09/370,700 patent/US6274350B1/en not_active Expired - Lifetime
-
2000
- 2000-06-23 US US09/603,207 patent/US6521406B1/en not_active Expired - Lifetime
- 2000-09-04 IL IL138241A patent/IL138241A/en not_active IP Right Cessation
-
2002
- 2002-12-23 US US10/329,148 patent/US7015001B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2002505881A (ja) | 2002-02-26 |
BR9909257B1 (pt) | 2014-01-14 |
TWI237058B (en) | 2005-08-01 |
CA2322449A1 (en) | 1999-09-16 |
US7015001B2 (en) | 2006-03-21 |
CN1227362C (zh) | 2005-11-16 |
ID26862A (id) | 2001-02-15 |
DE69937732T2 (de) | 2008-12-04 |
US6143526A (en) | 2000-11-07 |
EP1062345A1 (de) | 2000-12-27 |
WO1999046387A9 (en) | 2001-10-04 |
CN1298447A (zh) | 2001-06-06 |
CA2322449C (en) | 2013-01-15 |
US6274350B1 (en) | 2001-08-14 |
AR014687A1 (es) | 2001-03-28 |
NZ506624A (en) | 2003-08-29 |
ES2299240T3 (es) | 2008-05-16 |
IL138241A0 (en) | 2001-10-31 |
AU2680099A (en) | 1999-09-27 |
BR9909257A (pt) | 2000-11-28 |
KR100588436B1 (ko) | 2006-06-13 |
ZA991837B (en) | 2000-09-08 |
US20040023343A1 (en) | 2004-02-05 |
EP1062345B1 (de) | 2007-12-12 |
US6521406B1 (en) | 2003-02-18 |
ATE380872T1 (de) | 2007-12-15 |
WO1999046387A1 (en) | 1999-09-16 |
IL138241A (en) | 2007-09-20 |
AU764737B2 (en) | 2003-08-28 |
KR20010041750A (ko) | 2001-05-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69937732D1 (de) | Biosynthetische gene zur spinosyn-insektizidherstellung | |
IL139093A0 (en) | Optimization of pest resistance genes using dna shuffling | |
DK0910633T3 (da) | Hybrid polyketidsyntase I-gen | |
AU2001251086A1 (en) | Microchip arrays of regulatory genes | |
EE200100174A (et) | 1-desoksü-D-ksüluloosi biosünteesiraja geenid | |
PL351816A1 (en) | Transposon−based genetic marker | |
AU2001249662A1 (en) | 6-methoxy-2-naphthylacetic acid prodrugs | |
TWI328610B (en) | Biosynthetic genes for butenyl-spinosyn insecticide production | |
AU2001282894A1 (en) | Transgenic mice containing targeted gene disruptions | |
DK1021943T3 (da) | Landbrugsfordelermaskine | |
AU2002239540A1 (en) | Transgenic mice containing channel protein target gene disruptions | |
IL151759A0 (en) | Transgenic mice containing targeted gene disruptions | |
AU2002217989A1 (en) | Transgenic mice containing targeted gene disruptions | |
AU3870999A (en) | Plant gene that regulates dna methylation | |
EP1076093A4 (de) | Gen der sakaranetin-synthase | |
GB2362383B (en) | Gene expression system | |
AU2002239539A1 (en) | Transgenic mice containing targeted gene disruptions | |
AU2002337695A1 (en) | High-protein-phenotype-associated plant genes | |
AU2001274256A1 (en) | Plant resistance gene | |
AU2001273383A1 (en) | Transgenic mice containing targeted gene disruptions | |
AU2001271880A1 (en) | Transgenic mice containing targeted phosphatase gene disruptions | |
AU2002254529A1 (en) | Nucleic acids for transgene expression | |
AU5429999A (en) | Plant resistance gene | |
GB9921239D0 (en) | Plant resistance gene | |
AU2001279929A1 (en) | Means for targeting nucleic acid repeat regions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |