AR014687A1 - VECTOR DE ADN RECOMBINANTE QUE CODIFICA UNA ENZIMA DE BIOSíNTESIS DE ESPINOSINA, MÉTODO PARA PRODUCIR ESPINOSINA EN CANTIDADES INCREMENTADAS Y PROCESO PARA PRODUCIR UN COMPUESTO DE ESPINOSINA USANDO DICHO VECTOR. - Google Patents

VECTOR DE ADN RECOMBINANTE QUE CODIFICA UNA ENZIMA DE BIOSíNTESIS DE ESPINOSINA, MÉTODO PARA PRODUCIR ESPINOSINA EN CANTIDADES INCREMENTADAS Y PROCESO PARA PRODUCIR UN COMPUESTO DE ESPINOSINA USANDO DICHO VECTOR.

Info

Publication number
AR014687A1
AR014687A1 ARP990100978A ARP990100978A AR014687A1 AR 014687 A1 AR014687 A1 AR 014687A1 AR P990100978 A ARP990100978 A AR P990100978A AR P990100978 A ARP990100978 A AR P990100978A AR 014687 A1 AR014687 A1 AR 014687A1
Authority
AR
Argentina
Prior art keywords
espinosine
produce
vector
spinosine
composite
Prior art date
Application number
ARP990100978A
Other languages
English (en)
Inventor
Richard H Baltz
M Christine Broughton
Kathryn P Crawford
Krishnamurthy Woodlawn Madduri
Donald J Merlo
Patti J Treadway
Jan R Turner
Clive Waldron
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of AR014687A1 publication Critical patent/AR014687A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
ARP990100978A 1998-03-09 1999-03-08 VECTOR DE ADN RECOMBINANTE QUE CODIFICA UNA ENZIMA DE BIOSíNTESIS DE ESPINOSINA, MÉTODO PARA PRODUCIR ESPINOSINA EN CANTIDADES INCREMENTADAS Y PROCESO PARA PRODUCIR UN COMPUESTO DE ESPINOSINA USANDO DICHO VECTOR. AR014687A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/036,987 US6143526A (en) 1998-03-09 1998-03-09 Biosynthetic genes for spinosyn insecticide production

Publications (1)

Publication Number Publication Date
AR014687A1 true AR014687A1 (es) 2001-03-28

Family

ID=21891822

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990100978A AR014687A1 (es) 1998-03-09 1999-03-08 VECTOR DE ADN RECOMBINANTE QUE CODIFICA UNA ENZIMA DE BIOSíNTESIS DE ESPINOSINA, MÉTODO PARA PRODUCIR ESPINOSINA EN CANTIDADES INCREMENTADAS Y PROCESO PARA PRODUCIR UN COMPUESTO DE ESPINOSINA USANDO DICHO VECTOR.

Country Status (18)

Country Link
US (4) US6143526A (es)
EP (1) EP1062345B1 (es)
JP (1) JP2002505881A (es)
KR (1) KR100588436B1 (es)
CN (1) CN1227362C (es)
AR (1) AR014687A1 (es)
AT (1) ATE380872T1 (es)
AU (1) AU764737B2 (es)
BR (1) BR9909257B1 (es)
CA (1) CA2322449C (es)
DE (1) DE69937732T2 (es)
ES (1) ES2299240T3 (es)
ID (1) ID26862A (es)
IL (2) IL138241A0 (es)
NZ (1) NZ506624A (es)
TW (1) TWI237058B (es)
WO (1) WO1999046387A1 (es)
ZA (1) ZA991837B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
WO2001016303A2 (de) * 1999-08-27 2001-03-08 Bayer Aktiengesellschaft Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren
AR033022A1 (es) 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina
KR20100039443A (ko) * 2001-08-06 2010-04-15 큐비스트 파마슈티컬즈 인코포레이티드 답토마이신 생합성 유전자 클러스터에 관련된 조성물 및 방법
JP4765032B2 (ja) 2002-02-19 2011-09-07 ダウ・アグロサイエンス・エル・エル・シー 新規スピノシンを産生するポリケチド合成酵素
EP1477563A3 (en) * 2003-05-16 2004-11-24 Wyeth Cloning genes from streptomyces cyaneogriseus subsp.noncyanogenus for biosynthesis of antibiotics and methods of use
GB0327721D0 (en) * 2003-11-28 2003-12-31 Biotica Tech Ltd Polyketides and their synthesis
EP2343975B8 (en) * 2008-09-22 2012-10-24 Entarco SA Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms
TW201041507A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041509A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041510A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041508A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
WO2010150100A1 (en) 2009-06-24 2010-12-29 Entarco Sa The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
CN102191208A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 高产多杀菌素的基因工程菌及其制备方法
JP2013531976A (ja) * 2010-05-11 2013-08-15 ダウ アグロサイエンシィズ エルエルシー ｓｐｎＫ菌株
WO2012085683A1 (en) 2010-12-22 2012-06-28 Entarco Sa The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
US20120196770A1 (en) 2011-01-28 2012-08-02 Amyris, Inc. Gel-encapsulated microcolony screening
EP2998399A1 (en) 2011-05-03 2016-03-23 Dow AgroSciences LLC Enhancing spinosyn production with oxygen binding proteins
US9404107B2 (en) * 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
US8741603B2 (en) 2011-05-03 2014-06-03 Agrigenetics Inc. Enhancing spinosyn production with oxygen binding proteins
WO2012158466A1 (en) 2011-05-13 2012-11-22 Amyris, Inc. Methods and compositions for detecting microbial production of water-immiscible compounds
CN103764668B (zh) * 2011-07-09 2016-08-17 加利福尼亚大学董事会 白血病干细胞靶向配体及应用方法
US9631195B2 (en) * 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
AU2013299608B2 (en) 2012-08-07 2019-02-21 Amyris, Inc. Methods for stabilizing production of acetyl-coenzyme a derived compounds
WO2014144135A2 (en) 2013-03-15 2014-09-18 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds
CA2918891C (en) 2013-08-07 2023-03-14 Amyris, Inc. Methods for stabilizing production of acetyl-coenzyme a derived compounds
CN103740631B (zh) * 2013-12-31 2015-09-30 天津大学 能提高多杀菌素产量的基因工程菌及构建方法及应用
JP6641366B2 (ja) * 2014-11-14 2020-02-05 浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． スピノサド異種発現株およびその構築方法ならびに使用
AU2016284696B2 (en) 2015-06-25 2021-10-28 Amyris, Inc. Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds
WO2017040763A1 (en) 2015-09-03 2017-03-09 Agrimetis, Llc Spinosyn derivatives as insecticides
KR20190103341A (ko) 2017-01-13 2019-09-04 에그리메티스, 엘엘씨 아지리딘 스피노신 유도체 및 제조 방법
WO2018226810A1 (en) * 2017-06-06 2018-12-13 Zymergen Inc. High throughput transposon mutagenesis
CN109096366B (zh) * 2017-06-21 2021-09-10 中南大学 Rgd环肽偶联亲脂性阳离子多杀菌素衍生物及其制备方法和应用

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EP0463707A1 (en) * 1985-12-17 1992-01-02 Lubrizol Genetics Inc. Production of polyketide antibiotics
US5672497A (en) * 1986-03-21 1997-09-30 Eli Lilly And Company Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms
US4874748A (en) * 1986-03-24 1989-10-17 Abbott Laboratories Cloning vectors for streptomyces and use thereof in macrolide antibiotic production
US5149638A (en) * 1988-09-29 1992-09-22 Eli Lilly And Company Tylosin biosynthetic genes tylA, tylB and tylI
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
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WO1993013663A1 (en) * 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
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US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
US5712146A (en) * 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
DK0725778T3 (da) * 1993-09-20 2001-12-17 Univ Leland Stanford Junior Rekombinant produktion af hidtil ukendte polyketider
US5672491A (en) * 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
DE19957268A1 (de) * 1999-08-27 2001-03-08 Bayer Ag Nucleinsäuren, die für Enzymaktivitäten der Spinosyn-Biosynthese kodieren
WO2001016303A2 (de) * 1999-08-27 2001-03-08 Bayer Aktiengesellschaft Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren
AR033022A1 (es) * 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina

Also Published As

Publication number Publication date
US7015001B2 (en) 2006-03-21
BR9909257B1 (pt) 2014-01-14
JP2002505881A (ja) 2002-02-26
ID26862A (id) 2001-02-15
AU2680099A (en) 1999-09-27
IL138241A (en) 2007-09-20
EP1062345B1 (en) 2007-12-12
TWI237058B (en) 2005-08-01
IL138241A0 (en) 2001-10-31
CN1227362C (zh) 2005-11-16
ATE380872T1 (de) 2007-12-15
ES2299240T3 (es) 2008-05-16
ZA991837B (en) 2000-09-08
EP1062345A1 (en) 2000-12-27
CN1298447A (zh) 2001-06-06
DE69937732T2 (de) 2008-12-04
WO1999046387A9 (en) 2001-10-04
BR9909257A (pt) 2000-11-28
US20040023343A1 (en) 2004-02-05
DE69937732D1 (de) 2008-01-24
KR20010041750A (ko) 2001-05-25
CA2322449C (en) 2013-01-15
CA2322449A1 (en) 1999-09-16
NZ506624A (en) 2003-08-29
WO1999046387A1 (en) 1999-09-16
AU764737B2 (en) 2003-08-28
US6274350B1 (en) 2001-08-14
US6143526A (en) 2000-11-07
US6521406B1 (en) 2003-02-18
KR100588436B1 (ko) 2006-06-13

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