DE69935721T2 - Kälteadaptierte Pferdeinfluenzaviren - Google Patents

Kälteadaptierte Pferdeinfluenzaviren Download PDF

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Publication number
DE69935721T2
DE69935721T2 DE69935721T DE69935721T DE69935721T2 DE 69935721 T2 DE69935721 T2 DE 69935721T2 DE 69935721 T DE69935721 T DE 69935721T DE 69935721 T DE69935721 T DE 69935721T DE 69935721 T2 DE69935721 T2 DE 69935721T2
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DE
Germany
Prior art keywords
virus
cold
equine influenza
seq
influenza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69935721T
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German (de)
English (en)
Other versions
DE69935721D1 (de
Inventor
Patricia W. Pittsburgh DOWLING
Julius S. Pittsburgh YOUNGNER
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University of Pittsburgh
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University of Pittsburgh
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Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Publication of DE69935721D1 publication Critical patent/DE69935721D1/de
Application granted granted Critical
Publication of DE69935721T2 publication Critical patent/DE69935721T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16161—Methods of inactivation or attenuation
    • C12N2760/16164—Methods of inactivation or attenuation by serial passage

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69935721T 1998-08-13 1999-08-12 Kälteadaptierte Pferdeinfluenzaviren Expired - Lifetime DE69935721T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US133921 1998-08-13
US09/133,921 US6177082B1 (en) 1998-08-13 1998-08-13 Cold-adapted equine influenza viruses
PCT/US1999/018583 WO2000009702A1 (en) 1998-08-13 1999-08-12 Cold-adapted equine influenza viruses

Publications (2)

Publication Number Publication Date
DE69935721D1 DE69935721D1 (de) 2007-05-16
DE69935721T2 true DE69935721T2 (de) 2008-02-07

Family

ID=22460917

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69935721T Expired - Lifetime DE69935721T2 (de) 1998-08-13 1999-08-12 Kälteadaptierte Pferdeinfluenzaviren

Country Status (10)

Country Link
US (3) US6177082B1 (enExample)
EP (2) EP1105497B1 (enExample)
JP (3) JP4583602B2 (enExample)
AT (1) ATE358722T1 (enExample)
AU (1) AU760356B2 (enExample)
CA (1) CA2339089C (enExample)
DE (1) DE69935721T2 (enExample)
DK (1) DK1105497T3 (enExample)
ES (1) ES2286892T3 (enExample)
WO (1) WO2000009702A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711389D0 (en) * 1997-06-04 1997-07-30 Univ Wales The Bacterial pheromones and uses therefor
US6482414B1 (en) 1998-08-13 2002-11-19 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
US6177082B1 (en) 1998-08-13 2001-01-23 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
DE60125736D1 (de) * 2000-04-03 2007-02-15 Univ Pittsburgh Zusammensetzungen, die kälteangepasste pferdeinfluenzaviren enthaltende, für die behandlung von bestehende virusinfektionen des atmungssystems
JP2002153262A (ja) * 2000-11-20 2002-05-28 Shibuya Kogyo Co Ltd 鶏卵の処理方法および処理装置
US7923023B2 (en) * 2002-02-25 2011-04-12 Astech International LLC Method and composition for delivery of medicants to animals
CN103540613A (zh) 2002-04-26 2014-01-29 米迪缪尼有限公司 制备流感病毒的多质粒系统
US20050158342A1 (en) * 2003-12-23 2005-07-21 Medimmune, Inc. Multi plasmid system for the production of influenza virus
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
EP1597400B8 (en) * 2003-02-25 2013-10-09 MedImmune, LLC Methods of producing influenza vaccine compositions
US20060110406A1 (en) * 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
CN1925870A (zh) * 2003-05-15 2007-03-07 俄克拉荷马州大学评议会 表达马－2型流感病毒ha1的dna疫苗
WO2006009871A1 (en) * 2004-06-17 2006-01-26 W5 Networks, Inc. Low power wireless communication system and protocol
US7572620B2 (en) 2005-01-11 2009-08-11 Wisconsin Alumni Research Foundation H3 equine influenza A virus
ES2570758T3 (es) * 2005-04-21 2016-05-20 Univ Florida Materiales y métodos para el control de enfermedades respiratorias en cánidos
US11865172B2 (en) 2005-04-21 2024-01-09 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US20080241184A1 (en) * 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
KR20110126726A (ko) * 2005-10-07 2011-11-23 화이자 프로덕츠 인코포레이티드 개과 동물의 인플루엔자의 치료를 위한 백신 및 방법
US7468187B2 (en) 2005-10-18 2008-12-23 Iowa State University Research Foundation, Inc. Canine influenza virus and related compositions and methods of use
AU2013205112C1 (en) * 2005-10-19 2015-12-03 Cornell Research Foundation, Inc. Influenza viruses able to infect canids, uses thereof
BRPI0617735B1 (pt) * 2005-10-19 2022-05-17 University Of Florida Research Foundation Inc Composições compreendendo vírus isolados, polinucleotídeos, ou polipeptídeos, construções de expressão, vacinas, kits para proteger um canino da infecção do vírus influenza, uso do vírus na preparação de composição farmacêutica bem como método in vitro para detecção de um vírus influenza que é capaz de infectar um animal canídeo
CA2626875A1 (en) * 2005-11-01 2007-05-10 Intervet International B.V. Prime boost vaccine for the protection of equines against equine influenza
EP1779866A1 (en) 2005-11-01 2007-05-02 Intervet International BV Prime-boost vaccine for the protection of equines against viral infection
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
JP5666905B2 (ja) 2007-06-18 2015-02-12 メディミューン，エルエルシー ヘマグルチニンポリペプチド中に変化を有するインフルエンザｂウイルス
MX350718B (es) 2011-03-14 2017-09-14 Boehringer Ingelheim Vetmedica Inc Vacuna de rinitis equina.
KR101490292B1 (ko) 2012-04-16 2015-02-04 한국생명공학연구원 신규한 ｈ3ｎ8 말 인플루엔자 바이러스
JP2013099339A (ja) * 2013-01-04 2013-05-23 Wisconsin Alumni Research Foundation Ｈ３型ウマａ型インフルエンザウイルス
US10080792B2 (en) 2013-09-23 2018-09-25 Engen Bio, Inc. Influenza vaccine and therapy
CN104436157A (zh) 2013-09-23 2015-03-25 恩金生物有限公司 流感疫苗和治疗
US10555998B2 (en) 2014-11-24 2020-02-11 Intervet Inc. Inactivated equine influenza virus vaccines
EP4076513A1 (en) 2019-12-18 2022-10-26 Intervet International B.V. Oral respiratory vaccine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518347A (en) 1965-05-28 1970-06-30 Inst Microbiologie Et D Hygien Vaccine for equine influenza
US3992522A (en) * 1973-01-24 1976-11-16 The United States Of America As Represented By The Department Of Health, Education And Welfare Temperature-sensitive recombinant mutant viruses and a process for producing same
SE434346C (sv) * 1982-04-07 1985-10-28 Johann Haberl Cyklonavskiljare med filterenhet for avskiljning av stoff fran gas, varvid en veckad filterenhet er anordnad med en ringspalt mot avskiljarens centralror
US4683137A (en) 1982-04-16 1987-07-28 Cornell Research Foundation, Inc. Temperature sensitive reassortant viruses and a vaccine against equine influenza
AU558483B2 (en) 1982-04-16 1987-01-29 Cornell Research Foundation Inc. Temperature sensitive reassortant viruses and a vaccine against equine influenza
GB8300467D0 (en) 1983-01-08 1983-02-09 Wellcome Found Equine influenza
US4631191A (en) 1985-06-20 1986-12-23 Biotechnology Research Partners, Ltd. Methods and compositions useful in preventing equine influenza
US4920213A (en) 1985-06-20 1990-04-24 Biotechnology Research Partners, Ltd. Method and compositions useful in preventing equine influenza
US5149531A (en) 1990-06-27 1992-09-22 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of using cold-adapted live influenza virus vaccine as an antiviral agent against influenza
IL105456A (en) 1992-04-21 1996-12-05 American Home Prod Vaccines of attenuated respiratory syncytial virus
US5690937A (en) 1995-06-05 1997-11-25 Aviron Temperature sensitive clustered changed-to-alanine mutants of influenza virus PB2 gene
US6177082B1 (en) 1998-08-13 2001-01-23 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses

Also Published As

Publication number Publication date
JP5261338B2 (ja) 2013-08-14
JP2002522078A (ja) 2002-07-23
CA2339089A1 (en) 2000-02-24
DE69935721D1 (de) 2007-05-16
ATE358722T1 (de) 2007-04-15
EP1854886A2 (en) 2007-11-14
US20030180322A1 (en) 2003-09-25
US6177082B1 (en) 2001-01-23
JP2009297040A (ja) 2009-12-24
WO2000009702A1 (en) 2000-02-24
JP4583602B2 (ja) 2010-11-17
ES2286892T3 (es) 2007-12-01
DK1105497T3 (da) 2007-07-30
CA2339089C (en) 2009-06-02
EP1854886A3 (en) 2007-11-21
JP2012085657A (ja) 2012-05-10
AU760356B2 (en) 2003-05-15
EP1105497B1 (en) 2007-04-04
AU5487799A (en) 2000-03-06
US6649169B2 (en) 2003-11-18
US6436408B1 (en) 2002-08-20
EP1105497A1 (en) 2001-06-13

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: UNIVERSITY OF PITTSBURGH, PITTSBURGH, PA., US

8327 Change in the person/name/address of the patent owner

Owner name: UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH S, US

8364 No opposition during term of opposition