ES2570758T3 - Materiales y métodos para el control de enfermedades respiratorias en cánidos - Google Patents

Materiales y métodos para el control de enfermedades respiratorias en cánidos

Info

Publication number
ES2570758T3
ES2570758T3 ES06769869T ES06769869T ES2570758T3 ES 2570758 T3 ES2570758 T3 ES 2570758T3 ES 06769869 T ES06769869 T ES 06769869T ES 06769869 T ES06769869 T ES 06769869T ES 2570758 T3 ES2570758 T3 ES 2570758T3
Authority
ES
Spain
Prior art keywords
amino acid
canids
materials
methods
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06769869T
Other languages
English (en)
Inventor
Patti C Crawford
Paul J Gibbs
Edward J Dubovi
Ruben O Donis
Jacqueline Katz
Alexander I Klimov
William L Castleman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Cornell Research Foundation Inc
University of Florida
University of Florida Research Foundation Inc
Original Assignee
US Department of Health and Human Services
Cornell Research Foundation Inc
University of Florida
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, Cornell Research Foundation Inc, University of Florida, University of Florida Research Foundation Inc filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of ES2570758T3 publication Critical patent/ES2570758T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/11—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un virus de la influenza A canina aislado que es capaz de infectar un animal cánido, en donde el virus de la influenza comprende un polipéptido de hemaglutinina (HA) o un polinucleótido que codifica un polipéptido de HA, en donde el polipéptido de HA comprende: (a) la secuencia de aminoácidos mostrada en cualquiera de los SEQ ID NO: 16, 32, 33 o 34; o (b) una secuencia de aminoácidos que tiene una identidad de secuencia de 95% o más con la secuencia mostrada en los SEQ ID NO: 33 o 34, en donde la secuencia de aminoácidos comprende una serina en la posición de aminoácido 82, una leucina en la posición de aminoácido 221, una treonina en la posición de aminoácido 327, y una treonina en la posición de aminoácido 482.
ES06769869T 2005-04-21 2006-04-21 Materiales y métodos para el control de enfermedades respiratorias en cánidos Active ES2570758T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67344305P 2005-04-21 2005-04-21
PCT/US2006/015090 WO2006116082A1 (en) 2005-04-21 2006-04-21 Materials and methods for respiratory disease control in canines

Publications (1)

Publication Number Publication Date
ES2570758T3 true ES2570758T3 (es) 2016-05-20

Family

ID=37215064

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06769869T Active ES2570758T3 (es) 2005-04-21 2006-04-21 Materiales y métodos para el control de enfermedades respiratorias en cánidos

Country Status (17)

Country Link
EP (3) EP2489739B1 (es)
JP (6) JP2008536526A (es)
KR (3) KR101738937B1 (es)
CN (3) CN107099512A (es)
AU (1) AU2006240038B2 (es)
BR (2) BRPI0610503B1 (es)
CA (1) CA2606429A1 (es)
ES (1) ES2570758T3 (es)
HK (1) HK1111729A1 (es)
IL (3) IL186710A (es)
MX (3) MX339202B (es)
NO (2) NO345667B1 (es)
NZ (2) NZ562661A (es)
RU (2) RU2449014C2 (es)
SG (2) SG10201910006WA (es)
WO (1) WO2006116082A1 (es)
ZA (1) ZA200708897B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
MX339202B (es) * 2005-04-21 2016-05-13 Univ Florida Materiales y metodos para el control de enfermedades respiratorias en caninos.
US11865172B2 (en) 2005-04-21 2024-01-09 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
CA2605015C (en) * 2005-05-06 2013-09-10 Gen-Probe Incorporated Compositions and assays to detect influenza virus a and b nucleic acids
US7425336B2 (en) * 2005-08-25 2008-09-16 Mevial Limited Canine influenza vaccines
JP4667507B2 (ja) 2005-10-07 2011-04-13 ファイザー・プロダクツ・インク イヌインフルエンザを治療するワクチンおよび方法
US7468187B2 (en) 2005-10-18 2008-12-23 Iowa State University Research Foundation, Inc. Canine influenza virus and related compositions and methods of use
AU2013205112C1 (en) * 2005-10-19 2015-12-03 Cornell Research Foundation, Inc. Influenza viruses able to infect canids, uses thereof
JP2009512449A (ja) * 2005-10-19 2009-03-26 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド イヌにおける呼吸器疾患管理のための材料および方法
EP1941033A2 (en) * 2005-10-20 2008-07-09 Wyeth a Corporation of the State of Delaware Compositions and methods for the treatment of canine influenza virus disease
GB0613977D0 (en) 2006-02-07 2006-08-23 Peptcell Ltd Peptide sequences and compositions
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
CA2667454C (en) * 2006-10-25 2015-12-01 Intervet International B.V. Feline influenza vaccine and method of use
CN101838708B (zh) * 2010-03-30 2012-07-18 华南农业大学 一种检测犬流感的方法
CN105263954B (zh) * 2013-02-07 2019-12-03 麻省理工学院 H5流感的人类适应
CN103881983B (zh) * 2014-03-07 2016-08-31 中国农业科学院哈尔滨兽医研究所 重组犬流感病毒毒株、其制备方法及由其制备得到的疫苗
WO2017004453A1 (en) * 2015-07-02 2017-01-05 Indevr, Inc. Universal priming mixture for amplification of influenza viral gene segments for diagnostic applications
CN110592276A (zh) * 2019-07-08 2019-12-20 北京世纪元亨动物防疫技术有限公司 用于检测犬流感病毒的特异性引物及试剂盒
CN115074461B (zh) * 2021-03-11 2023-08-25 上海市农业科学院 犬流感病毒、犬冠状病毒和犬呼肠孤病毒的三重pcr检测方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034322A (en) 1983-01-17 1991-07-23 Monsanto Company Chimeric genes suitable for expression in plant cells
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5106739A (en) 1989-04-18 1992-04-21 Calgene, Inc. CaMv 355 enhanced mannopine synthase promoter and method for using same
US6309647B1 (en) * 1999-07-15 2001-10-30 Aventis Pasteur Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants
US5756102A (en) * 1990-11-20 1998-05-26 Virogenetics Corporation Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5612487A (en) 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
US5484719A (en) 1991-08-26 1996-01-16 Edible Vaccines, Inc. Vaccines produced and administered through edible plants
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
RU2193065C2 (ru) * 1994-03-14 2002-11-20 Мерк энд Ко. Инк. Конструкция днк (варианты), днк-вектор, иммуногенная композиция против вируса гриппа, способ индукции иммунного ответа, вакцина и способ вакцинации
DK0752888T3 (da) * 1994-03-30 2007-12-03 Virogenetics Corp Nukleotid- og aminosyresekvenser af gB, gC- og gD-hunde-herpesvirus og anvendelser deraf
GB9524395D0 (en) 1995-11-29 1996-01-31 Nickerson Biocem Ltd Promoters
US6252139B1 (en) 1996-07-18 2001-06-26 The Salk Institute For Biological Studies Method of increasing growth and yield in plants
US6063385A (en) 1997-11-07 2000-05-16 Wisconsin Alumni Research Foundation DNA vaccine for parvovirus
US6472375B1 (en) 1998-04-16 2002-10-29 John Wayne Cancer Institute DNA vaccine and methods for its use
US6482414B1 (en) * 1998-08-13 2002-11-19 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
US6177082B1 (en) * 1998-08-13 2001-01-23 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
US6579528B1 (en) * 1998-08-13 2003-06-17 The University Of Pittsburgh - Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
WO2000031249A1 (en) 1998-11-24 2000-06-02 Pioneer Hi-Bred International, Inc. Root-preferred promoters and their use
JP2000230931A (ja) * 1998-12-07 2000-08-22 Katakura Industries Co Ltd 家畜インフルエンザウイルスに対する抗体の検出方法およびこれに用いるキット
DE19960843A1 (de) 1999-12-16 2001-06-28 Florian Grundler Wurzelspezifischer Promotor
IL153005A0 (en) * 2000-06-23 2003-06-24 American Cyanamid Co Nucleotide sequence of influenza a/udorn/72 (h3n2) genome
US6455760B1 (en) 2000-11-16 2002-09-24 The Salk Institute Of Biological Studies Expression of flavin-containing monoxygenases in plants
US20040067506A1 (en) 2000-12-04 2004-04-08 Ben Scheres Novel root specific promoter driving the expression of a novel lrr receptor-like kinase
WO2003086453A1 (en) * 2002-04-12 2003-10-23 Ilaria Capua Purified subfragment codifying for neuroaminidase, recombinant neuroaminidase and its use in zooprophylaxis
US7285656B2 (en) 2002-04-26 2007-10-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Natural Resources Canada, Canadian Forest Service Root-specific conifer gene promoter and its use
US20040123349A1 (en) 2002-12-20 2004-06-24 Qi Xie SINAT5, an Arabidopsis thaliana gene promotes ubiquitin related degradation
AU2004263816A1 (en) * 2003-05-15 2005-02-17 The Board Of Regents For Oklahoma State University DNA vaccine expressing HA1 of equine-2 influenza virus
CN1458168A (zh) * 2003-06-02 2003-11-26 中国农业科学院哈尔滨兽医研究所 重组猪流感病毒np抗原、其制备方法及在诊断中的应用
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
MX339202B (es) * 2005-04-21 2016-05-13 Univ Florida Materiales y metodos para el control de enfermedades respiratorias en caninos.
JP4667507B2 (ja) * 2005-10-07 2011-04-13 ファイザー・プロダクツ・インク イヌインフルエンザを治療するワクチンおよび方法
US7468187B2 (en) * 2005-10-18 2008-12-23 Iowa State University Research Foundation, Inc. Canine influenza virus and related compositions and methods of use
JP2009512449A (ja) * 2005-10-19 2009-03-26 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド イヌにおける呼吸器疾患管理のための材料および方法
EP1941033A2 (en) * 2005-10-20 2008-07-09 Wyeth a Corporation of the State of Delaware Compositions and methods for the treatment of canine influenza virus disease
US7682619B2 (en) * 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus

Also Published As

Publication number Publication date
HK1111729A1 (zh) 2008-08-15
IL208707B (en) 2020-01-30
CN103451158B (zh) 2018-11-23
IL249236B (en) 2021-07-29
RU2020100038A (ru) 2021-07-09
WO2006116082A1 (en) 2006-11-02
IL249236A0 (en) 2017-01-31
KR20140091770A (ko) 2014-07-22
JP2024043541A (ja) 2024-03-29
JP2020031658A (ja) 2020-03-05
IL186710A0 (en) 2008-02-09
RU2711791C2 (ru) 2020-01-22
AU2006240038B2 (en) 2012-07-05
MX339202B (es) 2016-05-13
CN103451158A (zh) 2013-12-18
JP2013031440A (ja) 2013-02-14
KR20150082628A (ko) 2015-07-15
NO342494B1 (no) 2018-06-04
JP2018050636A (ja) 2018-04-05
JP6042131B2 (ja) 2016-12-14
AU2006240038A1 (en) 2006-11-02
JP6301855B2 (ja) 2018-03-28
NO345667B1 (no) 2021-06-07
BRPI0610503B1 (pt) 2022-05-31
CN101253267A (zh) 2008-08-27
ZA200708897B (en) 2009-01-28
IL186710A (en) 2017-09-28
SG10201406043TA (en) 2014-11-27
SG10201910006WA (en) 2019-11-28
CN107099512A (zh) 2017-08-29
RU2449014C2 (ru) 2012-04-27
EP2495326A3 (en) 2013-08-28
NZ583564A (en) 2011-09-30
EP2495326A2 (en) 2012-09-05
KR101738940B1 (ko) 2017-06-08
RU2007143041A (ru) 2009-05-27
NO20075961L (no) 2008-01-21
MX2018010571A (es) 2022-01-25
EP2495326B1 (en) 2019-11-20
EP2489739B1 (en) 2019-11-20
KR101738937B1 (ko) 2017-05-23
EP1871885B1 (en) 2016-02-17
IL208707A0 (en) 2010-12-30
JP6663416B2 (ja) 2020-03-11
NZ562661A (en) 2010-04-30
KR101474011B1 (ko) 2014-12-23
EP1871885B8 (en) 2017-08-02
EP1871885A4 (en) 2009-09-16
EP1871885A1 (en) 2008-01-02
BR122018012345B1 (pt) 2021-10-26
JP2015144604A (ja) 2015-08-13
MX358750B (es) 2018-08-31
JP2008536526A (ja) 2008-09-11
NO20180601A1 (no) 2008-01-21
BRPI0610503A2 (pt) 2010-06-29
CA2606429A1 (en) 2006-11-02
RU2011153597A (ru) 2013-07-10
EP2489739A3 (en) 2013-08-28
KR20080039836A (ko) 2008-05-07
EP2489739A2 (en) 2012-08-22

Similar Documents

Publication Publication Date Title
ES2570758T3 (es) Materiales y métodos para el control de enfermedades respiratorias en cánidos
ES2691539T3 (es) Luciferasas de Oplophorus sintéticas con mayor emisión de luz
ECSP19034870A (es) Péptidos escindibles y proteínas insecticidas y nematicidas que los comprenden
ES2616658T3 (es) Péptidos que mimetizan el factor de crecimiento y sus usos
PE20110310A1 (es) Axmi-115, axmi-113, axmi-005, axmi-163 y axmi-184: proteinas insecticidas
NZ595736A (en) Chimeric viruses presenting non-native surface proteins and uses thereof
EA201892250A1 (ru) Вакцина против rsv
EA201592306A1 (ru) Вакцины против вируса гриппа и их применения
RS53872B1 (en) NEW AND POWERFUL CLASS II MHC PEPTIDES DERIVATED FROM SURVIVINE AND UNAURANTS
RS53455B (en) OPTIONS DERIVED FROM ActRIIB AND THEIR USE
AR056133A1 (es) Virus de influenza canina y composiciones relacionadas y metodos de uso
NO20063026L (no) Antistoffer
AR067980A1 (es) Peptidos de cdh3 y agentes que los comprenden
MX2021012991A (es) Antigenos de gripe recombinantes.
HRP20220980T1 (hr) Cjepiva protiv virusa influence i njihova uporaba
CL2017000200A1 (es) Célula huésped mejorada para producir proteinas
BR112016026842A2 (pt) preparação compreendendo fator viii e peptídeos de fator de von willebrand
PE20120400A1 (es) Contrucciones de casb7439
ATE493497T1 (de) Verfahren zur herstellung von oligopeptiden
DE60236579D1 (de) Bakteriophagenvermittelte impfung
CL2020002373A1 (es) Composición de vacuna que comprende un péptido aislado de piojo de mar; uso de la vacuna para para prevenir o controlar una infestación de piojos de mar en un salmónido; vector; célula hospedadora (divisional de la solicitud no. 201900422).
BR112022006578A2 (pt) Polipeptídeos de fusão e de hemaglutinina do vírus da cinomose canina
ES2557938T3 (es) Antagonistas de resistina y su uso
EA200901441A1 (ru) Новые молекулы антител и нуклеиновых кислот, связывающиеся с грибным белком теплового шока hsp90
MX2023000373A (es) Proteinas de fusion de proteinas de la espicula de coronavirus estabilizadas.