DE69934583D1 - Nukleinsäure-impfstoffe zur verhinderung der flaviviren-infektion - Google Patents
Nukleinsäure-impfstoffe zur verhinderung der flaviviren-infektionInfo
- Publication number
- DE69934583D1 DE69934583D1 DE69934583T DE69934583T DE69934583D1 DE 69934583 D1 DE69934583 D1 DE 69934583D1 DE 69934583 T DE69934583 T DE 69934583T DE 69934583 T DE69934583 T DE 69934583T DE 69934583 D1 DE69934583 D1 DE 69934583D1
- Authority
- DE
- Germany
- Prior art keywords
- flaviviren
- infection
- preventing
- nucleic acid
- acid vaccines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 229940023146 nucleic acid vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8790898P | 1998-06-04 | 1998-06-04 | |
US87908P | 1998-06-04 | ||
PCT/US1999/012298 WO1999063095A1 (en) | 1998-06-04 | 1999-06-03 | Nucleic acid vaccines for prevention of flavivirus infection |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69934583D1 true DE69934583D1 (de) | 2007-02-08 |
DE69934583T2 DE69934583T2 (de) | 2007-10-04 |
Family
ID=22207979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69934583T Expired - Lifetime DE69934583T2 (de) | 1998-06-04 | 1999-06-03 | Nukleinsäure-impfstoffe zur verhinderung der flaviviren-infektion |
Country Status (9)
Country | Link |
---|---|
US (3) | US7417136B1 (de) |
EP (1) | EP1084252B1 (de) |
JP (1) | JP4489943B2 (de) |
AU (1) | AU778988B2 (de) |
BR (1) | BR9910830A (de) |
CA (1) | CA2331368C (de) |
DE (1) | DE69934583T2 (de) |
IL (2) | IL139844A0 (de) |
WO (1) | WO1999063095A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU778988B2 (en) | 1998-06-04 | 2004-12-23 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Nucleic acid vaccines for prevention of flavivirus infection |
US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
US7425437B2 (en) | 1999-11-26 | 2008-09-16 | Crucell Holland B.V. | Vaccines against West Nile Virus |
AU3844101A (en) | 2000-02-16 | 2001-08-27 | Us Health | Avirulent, immunogenic flavivirus chimeras |
AU2007202304B2 (en) * | 2001-04-04 | 2010-03-18 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION | Nucleic acid vaccines for prevention of flavivirus infection |
PL212212B1 (pl) | 2001-07-27 | 2012-08-31 | Wyeth Corp | Kompozycja szczepionki przeciwko zakażeniu wirusem Zachodniego Nilu, kompozycja końskiej szczepionki, szczepionka wirusa Zachodniego Nilu oraz zastosowania |
RU2307872C2 (ru) * | 2002-10-09 | 2007-10-10 | СиАйДи КО., ЛТД | НОВАЯ ПОЛНОРАЗМЕРНАЯ ГЕНОМНАЯ PHK ВИРУСА ЯПОНСКОГО ЭНЦЕФАЛИТА, ПОЛУЧЕННАЯ ИЗ НЕЕ ИНФЕКЦИОННАЯ кДНК JEV И ИХ ПРИМЕНЕНИЕ |
CA2576798C (en) | 2004-07-27 | 2014-09-09 | Gwong-Jen J. Chang | Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use |
CA2591665C (en) | 2004-12-20 | 2015-05-05 | Crucell Holland B.V. | Binding molecules capable of neutralizing west nile virus and uses thereof |
AU2006245734C1 (en) | 2005-05-12 | 2012-05-24 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
CA3150411C (en) | 2009-07-31 | 2023-09-12 | Pnuvax Inc. | High yield yellow fever virus strain with increased propagation in cells |
US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
PE20211814A1 (es) | 2013-03-15 | 2021-09-14 | Takeda Vaccines Inc | Composiciones y metodos de construcciones quimericas del virus del dengue en vacunas |
CN105311646B (zh) * | 2015-05-05 | 2019-03-29 | 中国人民解放军第二军医大学 | 埃兹蛋白在防治乙型脑炎病毒感染中的应用 |
CN105311647B (zh) * | 2015-05-05 | 2018-11-30 | 中国人民解放军第二军医大学 | 丝切蛋白在防治乙型脑炎病毒感染中的应用 |
US10947277B2 (en) | 2016-06-13 | 2021-03-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays |
TWI599654B (zh) * | 2016-06-24 | 2017-09-21 | 國立中興大學 | 日本腦炎病毒類病毒顆粒表現質體及日本腦炎dna疫苗 |
US10898566B2 (en) | 2016-09-19 | 2021-01-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Zika virus vaccines |
WO2018152526A1 (en) | 2017-02-20 | 2018-08-23 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
US11464815B2 (en) | 2018-09-05 | 2022-10-11 | Takeda Vaccines, Inc. | Dengue vaccine unit dose and administration thereof |
US11426461B2 (en) | 2018-09-05 | 2022-08-30 | Takeda Vaccines, Inc. | Methods for preventing dengue and hepatitis A |
MX2021002586A (es) | 2018-09-05 | 2021-06-08 | Takeda Vaccines Inc | Dosis unitaria de vacuna contra el dengue y administracion de esta. |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53133627A (en) | 1977-04-25 | 1978-11-21 | Nippon Seibutsu Kagaku Kenkiyu | High purity deactivated vaccine for japanese encephalitis |
JPH0768267B2 (ja) | 1986-06-05 | 1995-07-26 | 財団法人阪大微生物病研究会 | フラビウイルス抗原 |
JPS634895A (ja) | 1986-06-24 | 1988-01-09 | Mitsubishi Electric Corp | オゾン精製水供給装置 |
JPS6325725A (ja) | 1986-07-18 | 1988-02-03 | Nec Corp | アドレス表分類方式 |
JPS63105682A (ja) | 1986-10-23 | 1988-05-10 | Mitsubishi Kasei Corp | デングウイルス3型由来のcDNA |
FR2614219B1 (fr) | 1987-04-23 | 1993-07-09 | Materiels Annexes Dialyse | Procede de fabrication de granules destines a la preparation de solutions de dialyse et installation pour sa mise en oeuvre. |
JPH084508B2 (ja) | 1987-09-16 | 1996-01-24 | 国立予防衛生研究所長 | 組み換えワクチニアウイルス |
US4783502A (en) | 1987-12-03 | 1988-11-08 | Ppg Industries, Inc. | Stable nonaqueous polyurethane microparticle dispersion |
JP2511494B2 (ja) | 1988-05-12 | 1996-06-26 | 善治 松浦 | 日本脳炎ウイルス表面抗原蛋白質の製造法 |
IL91304A0 (en) | 1988-08-20 | 1990-03-19 | Us Health | Recombinant vaccinia virus for prevention of disease caused by flavivirus |
JPH0425408A (ja) | 1990-05-21 | 1992-01-29 | Hitachi Ltd | ペレタイジングシステムの自動連続運転制御方法 |
FR2665710A1 (fr) | 1990-08-10 | 1992-02-14 | Pasteur Institut | Baculovirus recombinant exprimant les proteines e et ns1 de virus appartenant aux flaviviridae ou de virus apparentes aux flaviviridae, applications diagnostiques et therapeutiques. |
US5514375A (en) | 1990-08-15 | 1996-05-07 | Virogenetics Corporation | Flavivirus recombinant poxvirus vaccine |
MY109299A (en) | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
US5494671A (en) | 1990-08-27 | 1996-02-27 | The United States Of America As Represented By The Department Of Health And Human Services | C-terminally truncated dengue and Japanese encephalitis virus envelope proteins |
ES2153223T3 (es) | 1991-09-19 | 2001-02-16 | Us Health | Flavivirus quimericos y/o flavivirus de crecimiento restringido. |
JPH05276941A (ja) * | 1992-02-28 | 1993-10-26 | Nippon Zeon Co Ltd | フラビウイルス科に属するウイルスの表面抗原タンパク質を含む非感染性の構造物粒子の製造方法 |
JPH07265093A (ja) | 1994-03-30 | 1995-10-17 | Chemo Sero Therapeut Res Inst | 哺乳動物細胞を用いる日本脳炎ウイルス表面抗原蛋白質の製法 |
CA2224724C (en) | 1995-05-24 | 2007-12-04 | Hawaii Biotechnology Group, Inc. | Subunit vaccine against flavivirus infection |
US6136561A (en) | 1995-05-24 | 2000-10-24 | Hawaii Biotechnology Group, Inc. | Methods of preparing carboxy-terminally truncated recombinant flavivirus envelope glycoproteins employing drosophila melanogaster expression systems |
US6074865A (en) | 1995-07-20 | 2000-06-13 | The United States Of America As Represented By The Secretary Of The Army | Recombinant dengue virus DNA fragment |
US6455509B1 (en) * | 1996-06-04 | 2002-09-24 | The United States Of America As Represented By The Secretary Of The Navy | Dengue nucleic acid vaccines that induce neutralizing antibodies |
WO1998017814A2 (en) * | 1996-10-18 | 1998-04-30 | Valentis Inc. | Gene expression and delivery systems and uses |
DE69841690D1 (de) | 1997-02-28 | 2010-07-08 | Acambis Inc | Chimäre Impfstoffe gegen Flaviviren |
WO1999006068A2 (en) | 1997-07-31 | 1999-02-11 | Hawaii Biotechnology Group, Inc. | Recombinant dimeric envelope vaccine against flaviviral infection |
EP1047448B1 (de) * | 1997-11-20 | 2006-02-01 | United States Army Medical Research and Materiel Command | Dna impfstoffe gegen zecken-flavivieren |
AU778988B2 (en) | 1998-06-04 | 2004-12-23 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Nucleic acid vaccines for prevention of flavivirus infection |
AU2002305028A1 (en) | 2001-02-28 | 2002-10-28 | Brown University Research Foundation | West nile virus epitopes and uses thereof |
EP1372711A4 (de) | 2001-03-12 | 2005-06-01 | Univ Yale | Zusammensetzungen und verfahren mit west-nil-virus-polypeptiden |
JP5276941B2 (ja) | 2008-09-24 | 2013-08-28 | 株式会社村田製作所 | 大変位アクチュエータ |
-
1999
- 1999-06-03 AU AU43296/99A patent/AU778988B2/en not_active Expired
- 1999-06-03 WO PCT/US1999/012298 patent/WO1999063095A1/en active IP Right Grant
- 1999-06-03 CA CA002331368A patent/CA2331368C/en not_active Expired - Lifetime
- 1999-06-03 US US09/701,536 patent/US7417136B1/en not_active Expired - Fee Related
- 1999-06-03 BR BR9910830-5A patent/BR9910830A/pt active Search and Examination
- 1999-06-03 DE DE69934583T patent/DE69934583T2/de not_active Expired - Lifetime
- 1999-06-03 JP JP2000552289A patent/JP4489943B2/ja not_active Expired - Lifetime
- 1999-06-03 EP EP99955295A patent/EP1084252B1/de not_active Expired - Lifetime
- 1999-06-03 IL IL13984499A patent/IL139844A0/xx unknown
-
2000
- 2000-11-22 IL IL139844A patent/IL139844A/en not_active IP Right Cessation
-
2008
- 2008-05-16 US US12/122,330 patent/US8105609B2/en not_active Expired - Fee Related
-
2011
- 2011-12-28 US US13/338,529 patent/US8728488B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20080241186A1 (en) | 2008-10-02 |
WO1999063095A1 (en) | 1999-12-09 |
CA2331368A1 (en) | 1999-12-09 |
US7417136B1 (en) | 2008-08-26 |
US8105609B2 (en) | 2012-01-31 |
AU778988B2 (en) | 2004-12-23 |
IL139844A0 (en) | 2002-02-10 |
WO1999063095A9 (en) | 2000-06-02 |
AU4329699A (en) | 1999-12-20 |
US8728488B2 (en) | 2014-05-20 |
JP2002517200A (ja) | 2002-06-18 |
BR9910830A (pt) | 2001-02-13 |
CA2331368C (en) | 2009-02-10 |
DE69934583T2 (de) | 2007-10-04 |
JP4489943B2 (ja) | 2010-06-23 |
EP1084252A1 (de) | 2001-03-21 |
IL139844A (en) | 2008-11-03 |
US20120093862A1 (en) | 2012-04-19 |
EP1084252B1 (de) | 2006-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |