DE69930500T2 - Herzklappenprothese - Google Patents
Herzklappenprothese Download PDFInfo
- Publication number
- DE69930500T2 DE69930500T2 DE69930500T DE69930500T DE69930500T2 DE 69930500 T2 DE69930500 T2 DE 69930500T2 DE 69930500 T DE69930500 T DE 69930500T DE 69930500 T DE69930500 T DE 69930500T DE 69930500 T2 DE69930500 T2 DE 69930500T2
- Authority
- DE
- Germany
- Prior art keywords
- prosthetic
- valve body
- edge
- flap
- arcuate edge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000003709 heart valve Anatomy 0.000 title claims description 43
- 230000017531 blood circulation Effects 0.000 claims description 10
- 230000001788 irregular Effects 0.000 claims description 3
- 210000005069 ears Anatomy 0.000 description 14
- 238000011144 upstream manufacturing Methods 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 8
- 239000008280 blood Substances 0.000 description 8
- 239000013598 vector Substances 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 206010018910 Haemolysis Diseases 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 4
- 238000010276 construction Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000003628 erosive effect Effects 0.000 description 4
- 230000008588 hemolysis Effects 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 206010067171 Regurgitation Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000004323 axial length Effects 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 229910002804 graphite Inorganic materials 0.000 description 2
- 239000010439 graphite Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 239000002296 pyrolytic carbon Substances 0.000 description 2
- 238000009958 sewing Methods 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 101100004287 Caenorhabditis elegans best-6 gene Proteins 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 210000001520 comb Anatomy 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000003134 recirculating effect Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 201000009032 substance abuse Diseases 0.000 description 1
- 230000002885 thrombogenetic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2403—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with pivoting rigid closure members
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10449 | 1987-02-03 | ||
| US09/010,449 US6096075A (en) | 1998-01-22 | 1998-01-22 | Prosthetic heart valve |
| PCT/US1999/000301 WO1999037249A1 (en) | 1998-01-22 | 1999-01-07 | Prosthetic heart valve |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69930500D1 DE69930500D1 (de) | 2006-05-11 |
| DE69930500T2 true DE69930500T2 (de) | 2006-11-23 |
Family
ID=21745807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69930500T Expired - Lifetime DE69930500T2 (de) | 1998-01-22 | 1999-01-07 | Herzklappenprothese |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6096075A (enExample) |
| EP (1) | EP1049426B1 (enExample) |
| JP (1) | JP2002500923A (enExample) |
| AU (1) | AU736769B2 (enExample) |
| CA (1) | CA2318130C (enExample) |
| DE (1) | DE69930500T2 (enExample) |
| WO (1) | WO1999037249A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10182907B2 (en) | 2007-05-02 | 2019-01-22 | Novostia Sa | Mechanical prosthetic heart valve |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6395024B1 (en) | 1997-05-20 | 2002-05-28 | Triflo Medical, Inc. | Mechanical heart valve |
| US6730122B1 (en) * | 2000-11-28 | 2004-05-04 | St. Jude Medical, Inc. | Prosthetic heart valve with increased lumen |
| CN101134119A (zh) | 2002-05-24 | 2008-03-05 | 血管技术国际股份公司 | 用于涂覆医用植入物的组合物和方法 |
| US20080086202A1 (en) * | 2002-09-27 | 2008-04-10 | Didier Lapeyre | Mechanical heart valve |
| EP3308744B2 (en) | 2004-03-11 | 2023-08-02 | Percutaneous Cardiovascular Solutions Pty Limited | Percutaneous heart valve prosthesis |
| WO2006138380A2 (en) * | 2005-06-15 | 2006-12-28 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| WO2010053572A2 (en) | 2008-11-07 | 2010-05-14 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| EP2358297B1 (en) | 2008-11-21 | 2019-09-11 | Percutaneous Cardiovascular Solutions Pty Limited | Heart valve prosthesis |
| RU2398551C1 (ru) * | 2009-02-19 | 2010-09-10 | Общество с ограниченной ответственностью "Ремонтно-механический завод Кирово-Чепецкого химического комбината" | Протез клапана сердца |
| SI2506857T1 (en) | 2009-12-01 | 2018-08-31 | Translate Bio, Inc. | Delivery of mRNA for the enrichment of proteins and enzymes in human genetic diseases |
| US9193827B2 (en) | 2010-08-26 | 2015-11-24 | Massachusetts Institute Of Technology | Poly(beta-amino alcohols), their preparation, and uses thereof |
| CA2831392C (en) | 2011-03-28 | 2020-04-28 | Massachusetts Institute Of Technology | Conjugated lipomers and uses thereof |
| KR20220025112A (ko) | 2011-06-08 | 2022-03-03 | 샤이어 휴먼 지네틱 테라피즈 인크. | Mrna 전달을 위한 지질 나노입자 조성물 및 방법 |
| EP3536787A1 (en) | 2012-06-08 | 2019-09-11 | Translate Bio, Inc. | Nuclease resistant polynucleotides and uses thereof |
| EA201591229A1 (ru) | 2013-03-14 | 2016-01-29 | Шир Хьюман Дженетик Терапис, Инк. | Способы очистки матричной рнк |
| KR102311614B1 (ko) | 2013-03-14 | 2021-10-08 | 샤이어 휴먼 지네틱 테라피즈 인크. | Cftr mrna 조성물 및 관련 방법 및 사용 |
| US9315472B2 (en) | 2013-05-01 | 2016-04-19 | Massachusetts Institute Of Technology | 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof |
| ES2707966T3 (es) | 2013-10-22 | 2019-04-08 | Translate Bio Inc | Terapia de ARNm para la deficiencia en síntesis de argininosuccinato |
| EP3574923A1 (en) | 2013-10-22 | 2019-12-04 | Translate Bio, Inc. | Mrna therapy for phenylketonuria |
| ES3032935T3 (en) | 2013-10-22 | 2025-07-29 | Translate Bio Inc | Lipid formulations for delivery of messenger rna |
| EP4729528A3 (en) | 2014-04-25 | 2026-06-24 | Translate Bio, Inc. | Methods for purification of messenger rna |
| WO2015184256A2 (en) | 2014-05-30 | 2015-12-03 | Shire Human Genetic Therapies, Inc. | Biodegradable lipids for delivery of nucleic acids |
| KR102559979B1 (ko) | 2014-06-24 | 2023-07-25 | 샤이어 휴먼 지네틱 테라피즈 인크. | 핵산의 전달용 입체화학적으로 풍부한 조성물 |
| WO2016004202A1 (en) | 2014-07-02 | 2016-01-07 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
| MX2019010155A (es) | 2017-02-27 | 2020-12-10 | Translate Bio Inc | Arnm de cftr optimizado por codón novedoso. |
| IL270631B2 (en) | 2017-05-16 | 2024-03-01 | Translate Bio Inc | Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr |
| US11174500B2 (en) | 2018-08-24 | 2021-11-16 | Translate Bio, Inc. | Methods for purification of messenger RNA |
| AU2019384557B2 (en) | 2018-11-21 | 2025-07-17 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR |
| CA3155003A1 (en) | 2019-09-20 | 2021-03-25 | Translate Bio, Inc. | Mrna encoding engineered cftr |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4078268A (en) * | 1975-04-24 | 1978-03-14 | St. Jude Medical, Inc. | Heart valve prosthesis |
| US4276658A (en) * | 1977-11-02 | 1981-07-07 | St. Jude Medical, Inc. | Heart valve prosthesis |
| US4451937A (en) * | 1982-02-08 | 1984-06-05 | Hemex, Inc. | Heart valve having ear guided occluders |
| US4689046A (en) * | 1985-03-11 | 1987-08-25 | Carbomedics, Inc. | Heart valve prosthesis |
| US5123920A (en) * | 1990-06-13 | 1992-06-23 | Onx, Inc. | Prosthetic heart valve |
| FR2655843A1 (fr) * | 1989-12-20 | 1991-06-21 | Commissariat Energie Atomique | Valve cardiaque a clapets pivotant sur des billes. |
| RU1767723C (ru) * | 1990-08-14 | 1995-01-27 | Кирово-Чепецкий химический комбинат | Протез клапана сердца |
| US5152785A (en) * | 1991-03-25 | 1992-10-06 | Onx, Inc. | Prosthetic heart valve |
| AU2346992A (en) * | 1991-06-06 | 1993-01-08 | Medtronic, Inc. | Composite curvature bileaflet prosthetic heart valve |
| US5354330A (en) * | 1991-10-31 | 1994-10-11 | Ats Medical Inc. | Heart valve prosthesis |
| US5376111A (en) * | 1992-07-24 | 1994-12-27 | Onx, Inc. | Heart valve prostheses |
| US5824062A (en) * | 1995-03-29 | 1998-10-20 | Cv Dynamics, Inc. | Bileaflet heart valve having dynamic pivot mechanism |
| US5641324A (en) * | 1995-05-16 | 1997-06-24 | Medical Carbon Research Institute, Llc | Prosthetic heart valve |
| WO1997005834A1 (en) * | 1995-08-07 | 1997-02-20 | Baxter International Inc. | Bileaflet mechanical heart valve having arrowhead slot hinge configuration |
-
1998
- 1998-01-22 US US09/010,449 patent/US6096075A/en not_active Expired - Lifetime
-
1999
- 1999-01-07 WO PCT/US1999/000301 patent/WO1999037249A1/en not_active Ceased
- 1999-01-07 AU AU22153/99A patent/AU736769B2/en not_active Expired
- 1999-01-07 CA CA002318130A patent/CA2318130C/en not_active Expired - Lifetime
- 1999-01-07 DE DE69930500T patent/DE69930500T2/de not_active Expired - Lifetime
- 1999-01-07 EP EP99902094A patent/EP1049426B1/en not_active Expired - Lifetime
- 1999-01-07 JP JP2000528238A patent/JP2002500923A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10182907B2 (en) | 2007-05-02 | 2019-01-22 | Novostia Sa | Mechanical prosthetic heart valve |
Also Published As
| Publication number | Publication date |
|---|---|
| AU736769B2 (en) | 2001-08-02 |
| AU2215399A (en) | 1999-08-09 |
| EP1049426A1 (en) | 2000-11-08 |
| JP2002500923A (ja) | 2002-01-15 |
| CA2318130A1 (en) | 1999-07-29 |
| WO1999037249A1 (en) | 1999-07-29 |
| DE69930500D1 (de) | 2006-05-11 |
| EP1049426B1 (en) | 2006-03-22 |
| US6096075A (en) | 2000-08-01 |
| CA2318130C (en) | 2007-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |