DE69925624T2 - Nukleinsäure-markierungsverbindungen - Google Patents

Nukleinsäure-markierungsverbindungen Download PDF

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Publication number
DE69925624T2
DE69925624T2 DE69925624T DE69925624T DE69925624T2 DE 69925624 T2 DE69925624 T2 DE 69925624T2 DE 69925624 T DE69925624 T DE 69925624T DE 69925624 T DE69925624 T DE 69925624T DE 69925624 T2 DE69925624 T2 DE 69925624T2
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DE
Germany
Prior art keywords
nucleic acid
biotin
group
alkyl
labeled
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69925624T
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German (de)
English (en)
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DE69925624D1 (de
Inventor
H. Glenn MCGALL
D. Anthony BARONE
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Affymetrix Inc
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Affymetrix Inc
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Publication of DE69925624D1 publication Critical patent/DE69925624D1/de
Publication of DE69925624T2 publication Critical patent/DE69925624T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
DE69925624T 1998-07-31 1999-07-20 Nukleinsäure-markierungsverbindungen Expired - Lifetime DE69925624T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US126645 1987-12-01
US09/126,645 US20010018514A1 (en) 1998-07-31 1998-07-31 Nucleic acid labeling compounds
PCT/US1999/012390 WO2000006771A2 (en) 1998-07-31 1999-07-20 Nucleic acid labeling compounds

Publications (2)

Publication Number Publication Date
DE69925624D1 DE69925624D1 (de) 2005-07-07
DE69925624T2 true DE69925624T2 (de) 2006-04-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925624T Expired - Lifetime DE69925624T2 (de) 1998-07-31 1999-07-20 Nukleinsäure-markierungsverbindungen

Country Status (8)

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US (5) US20010018514A1 (US06844433-20050118-C00051.png)
EP (2) EP1124838B1 (US06844433-20050118-C00051.png)
JP (2) JP2002521495A (US06844433-20050118-C00051.png)
AT (1) ATE296833T1 (US06844433-20050118-C00051.png)
AU (1) AU5203599A (US06844433-20050118-C00051.png)
CA (1) CA2339016A1 (US06844433-20050118-C00051.png)
DE (1) DE69925624T2 (US06844433-20050118-C00051.png)
WO (1) WO2000006771A2 (US06844433-20050118-C00051.png)

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Publication number Publication date
US6596856B2 (en) 2003-07-22
WO2000006771A3 (en) 2001-06-21
US7491818B2 (en) 2009-02-17
US20010044531A1 (en) 2001-11-22
US20050164268A1 (en) 2005-07-28
US20040002595A1 (en) 2004-01-01
US7179905B2 (en) 2007-02-20
AU5203599A (en) 2000-02-21
EP1124838A2 (en) 2001-08-22
ATE296833T1 (de) 2005-06-15
WO2000006771A2 (en) 2000-02-10
US20010018514A1 (en) 2001-08-30
JP2006258818A (ja) 2006-09-28
US20030232979A1 (en) 2003-12-18
EP1589025A2 (en) 2005-10-26
US6844433B2 (en) 2005-01-18
DE69925624D1 (de) 2005-07-07
WO2000006771A9 (en) 2002-08-22
CA2339016A1 (en) 2000-02-10
EP1124838B1 (en) 2005-06-01
EP1589025A3 (en) 2006-04-19
JP2002521495A (ja) 2002-07-16

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