DE69924018D1 - Vorrichtung und verfahren zum abgeben von lungenaerosolen - Google Patents

Vorrichtung und verfahren zum abgeben von lungenaerosolen

Info

Publication number
DE69924018D1
DE69924018D1 DE69924018T DE69924018T DE69924018D1 DE 69924018 D1 DE69924018 D1 DE 69924018D1 DE 69924018 T DE69924018 T DE 69924018T DE 69924018 T DE69924018 T DE 69924018T DE 69924018 D1 DE69924018 D1 DE 69924018D1
Authority
DE
Germany
Prior art keywords
aerosolized
liquid
delivering
user
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69924018T
Other languages
English (en)
Other versions
DE69924018T2 (de
Inventor
C Zimlich
E Dvorsky
R Busick
D Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventaira Pharmaceuticals Inc
Original Assignee
Battelle Memorial Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute Inc filed Critical Battelle Memorial Institute Inc
Publication of DE69924018D1 publication Critical patent/DE69924018D1/de
Application granted granted Critical
Publication of DE69924018T2 publication Critical patent/DE69924018T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007Syringe-type or piston-type sprayers or atomisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/02Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A61M15/025Bubble jet droplet ejection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/16Arrangements for supplying liquids or other fluent material
    • B05B5/1691Apparatus to be carried on or by a person or with a container fixed to the discharge device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081Locking means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083Timers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
DE69924018T 1998-12-23 1999-12-22 Vorrichtung und verfahren zum abgeben von lungenaerosolen Expired - Lifetime DE69924018T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22024998A 1998-12-23 1998-12-23
US220249 1998-12-23
US09/469,042 US6397838B1 (en) 1998-12-23 1999-12-21 Pulmonary aerosol delivery device and method
US469042 1999-12-21
PCT/US1999/030675 WO2000038770A2 (en) 1998-12-23 1999-12-22 Pulmonary aerosol delivery device and method

Publications (2)

Publication Number Publication Date
DE69924018D1 true DE69924018D1 (de) 2005-04-07
DE69924018T2 DE69924018T2 (de) 2006-04-13

Family

ID=26914704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924018T Expired - Lifetime DE69924018T2 (de) 1998-12-23 1999-12-22 Vorrichtung und verfahren zum abgeben von lungenaerosolen

Country Status (12)

Country Link
US (4) US6397838B1 (de)
EP (1) EP1144033B1 (de)
JP (1) JP4369062B2 (de)
CN (1) CN1335783A (de)
AT (1) ATE289835T1 (de)
AU (1) AU764814B2 (de)
BR (1) BR9916533A (de)
CA (1) CA2355683C (de)
DE (1) DE69924018T2 (de)
HK (1) HK1043553A1 (de)
NZ (1) NZ512583A (de)
WO (1) WO2000038770A2 (de)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
BR0010262A (pt) * 1999-05-03 2002-01-15 Battelle Memorial Institute Composição para formar um aerossol, processo de preparação e de aerossolização de uma composição, e, dispositivo gerador de aerossol
US6397837B1 (en) * 1999-07-22 2002-06-04 Martin W. Ferris Inhaler assistive device
CA2405169C (en) 2000-04-03 2011-07-26 Battelle Memorial Institute Devices and formulations
WO2002013886A2 (en) * 2000-08-15 2002-02-21 University Of Kentucky Research Foundation Programmable multi-dose intranasal drug delivery device
US6435175B1 (en) * 2000-08-29 2002-08-20 Sensormedics Corporation Pulmonary drug delivery device
AU2001279544A1 (en) * 2000-09-20 2002-04-02 Franco Del Bon Inhalator and pertaining atomizer
JP2004526674A (ja) 2000-12-01 2004-09-02 バテル・メモリアル・インスティテュート 液体処方物中における生体分子の安定化のための方法
EP1382995B1 (de) 2001-04-25 2014-05-07 Panasonic Corporation Projektionsanzeigeeinrichtung
GB2384198B (en) 2002-01-18 2005-03-02 Profile Drug Delivery Ltd Nebulizer metering
DE20203999U1 (de) * 2002-03-13 2002-08-22 Solvay Fluor & Derivate Vorrichtung zur Bestimmung der physikalischen und chemischen Parameter von Aerosol-Formulierungen aus Dosieraerosolen
CA2495266A1 (en) * 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
US7681572B2 (en) * 2002-08-20 2010-03-23 Aga Ab Method and devices for administration of therapeutic gases
GB2395437C (en) 2002-11-20 2010-10-20 Profile Respiratory Systems Ltd Improved inhalation method and apparatus
GB2396825B (en) 2002-11-20 2004-12-08 Profile Respiratory Systems Lt Improved inhalation method and apparatus
CN101366569B (zh) * 2003-02-13 2015-11-25 布莱克和戴克公司 手持式擦洗工具
US7849850B2 (en) * 2003-02-28 2010-12-14 Battelle Memorial Institute Nozzle for handheld pulmonary aerosol delivery device
JP2006524418A (ja) * 2003-03-04 2006-10-26 博雅 東城 低表面エネルギー化合物でコーティングしたエレクトロスプレーエミッタ
US20040187864A1 (en) * 2003-03-24 2004-09-30 Cindet, Llc Inhalation device and method
CA2526222A1 (en) * 2003-05-16 2004-12-02 Arriva Pharmaceuticals, Inc. Treatment of respiratory disease associated with matrix metalloprotease inhibitors
US8371292B2 (en) * 2003-09-16 2013-02-12 Nycomed Gmbh Use of ciclesonide for the treatment of respiratory diseases
US7066029B2 (en) * 2003-09-25 2006-06-27 Deka Products Limited Partnership System and method for improved volume measurement
US7342660B2 (en) * 2003-09-25 2008-03-11 Deka Products Limited Partnership Detection system and method for aerosol delivery
US7607435B2 (en) * 2004-01-21 2009-10-27 Battelle Memorial Institute Gas or liquid flow sensor
CN100473464C (zh) 2004-02-09 2009-04-01 松下电工株式会社 静电喷涂设备
JP4415015B2 (ja) 2004-02-09 2010-02-17 パナソニック電工株式会社 静電噴霧装置
WO2005075090A1 (en) * 2004-02-09 2005-08-18 Matsushita Electric Works, Ltd. Electrostatic spraying device
US8474452B2 (en) 2004-02-24 2013-07-02 Microdose Therapeutx, Inc. Directional flow sensor inhaler
EP1720543A1 (de) * 2004-02-27 2006-11-15 Altana Pharma AG Kombination aus roflumilast und glycopryrronium
US20070134165A1 (en) * 2004-04-20 2007-06-14 Altana Pharma Ag Use of Ciclesonide for the Treatment of Respiratory Disease in a Smoking Patient
EP1607080B1 (de) * 2004-06-14 2008-08-06 Matsushita Electric Works, Ltd. Dampferzeuger
JP2008512428A (ja) * 2004-09-10 2008-04-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング シクレソニドとSykインヒビターとの組合せ物並びにその使用方法
US20080259519A1 (en) 2004-09-14 2008-10-23 Battelle Memorial Institute Highly-Aqueous, Non-Respirable Aerosols Containing Biologically-Active Ingredients, Method of Making, and Device Therefor
WO2006047453A2 (en) * 2004-10-22 2006-05-04 Charge Injection Technologies, Inc. Process for high throughput electrohydrodynamic spraying of fluids
US20060102175A1 (en) * 2004-11-18 2006-05-18 Nelson Stephen G Inhaler
EP1848542A1 (de) * 2005-02-11 2007-10-31 Battelle Memorial Institute Ehd-aerosol-abgabevorrichtung und sprühverfahren
CA2598990A1 (en) * 2005-02-25 2006-08-31 Battelle Memorial Institute Spray indication
US20070017505A1 (en) * 2005-07-15 2007-01-25 Lipp Brian A Dispensing device and method
US20080251551A1 (en) * 2005-08-22 2008-10-16 Medi-Stream Pty Ltd Medication Dispenser and Carrier Therefor
JP4674541B2 (ja) * 2005-12-22 2011-04-20 パナソニック電工株式会社 静電霧化装置及び静電霧化装置を備えた食品保管庫
CN104162201A (zh) 2006-02-09 2014-11-26 德卡产品有限公司 外围系统
US20090025713A1 (en) * 2006-02-10 2009-01-29 Pari Pharma Gmbh Nebulised Antibiotics for Inhalation Therapy
JP2009526565A (ja) * 2006-02-14 2009-07-23 バテル メモリアル インスティチュート 正確な計測システム
CA2649413A1 (en) 2006-02-14 2007-08-23 Battelle Memorial Institute Dissociated discharge ehd sprayer with electric field shield
US7673819B2 (en) * 2006-06-26 2010-03-09 Battelle Memorial Institute Handheld sprayer with removable cartridge and method of using same
US20070295329A1 (en) * 2006-06-13 2007-12-27 Lieberman Eric A Dose indicator
GB0612019D0 (en) 2006-06-16 2006-07-26 Aerstream Technology Ltd Load response circuit
WO2008002556A1 (en) * 2006-06-26 2008-01-03 Battelle Memorial Institute Cartridge having self-actuating seal for a wetted lead screw
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス, インコーポレイテッド スマートな非経口送達システム
KR100765493B1 (ko) 2006-08-28 2007-10-10 마츠시다 덴코 가부시키가이샤 정전 스프레이 장치
GB0625127D0 (en) * 2006-12-18 2007-01-24 Ici Ltd Electrostatic paint spray device
US20080287874A1 (en) * 2007-05-18 2008-11-20 Medtronic, Inc. Controlling dead volume of a piston pump using an adjustment screw
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
EP2534958A1 (de) 2007-12-14 2012-12-19 AeroDesigns, Inc Abgabe von Aerosol-sprühbaren Nahrungsmittelprodukten
US8502507B1 (en) 2012-03-29 2013-08-06 Accio Energy, Inc. Electro-hydrodynamic system
US8878150B2 (en) 2008-01-22 2014-11-04 Accio Energy, Inc. Electro-hydrodynamic wind energy system
DK2238678T3 (en) 2008-01-22 2016-02-01 Accio Energy Inc Electro-hydrodynamic wind energy system
CN102089027A (zh) * 2008-07-11 2011-06-08 Map药物公司 用于输送气雾剂药物的容器
EP2198972A1 (de) 2008-12-18 2010-06-23 Boehringer Ingelheim International GmbH Reservoir und Zerstäuber
JP5620466B2 (ja) 2009-03-17 2014-11-05 ベーリンガーインゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リザーバ及びアトマイザ
EP2425224A1 (de) 2009-04-28 2012-03-07 Boehringer Ingelheim International GmbH Verfahren zur prüfung der dichtheit eines mit einem fluid befüllten behälters
WO2010127178A1 (en) * 2009-04-29 2010-11-04 Accio Energy Inc. Electro-hydrodynamic wind energy systems and methods
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
US20110174304A1 (en) * 2010-01-21 2011-07-21 Triplett Ii Michael D Electrohydrodynamic aerosolization device having a time varying voltage
CN102905612A (zh) 2010-02-01 2013-01-30 普罗秋斯数字健康公司 双腕式数据采集系统
JP5841951B2 (ja) 2010-02-01 2016-01-13 プロテウス デジタル ヘルス, インコーポレイテッド データ収集システム
US8517729B2 (en) * 2010-03-04 2013-08-27 The University of Western Ontario and Trudell Medical International Oral mouthpiece and method for the use thereof
EP2558149A1 (de) * 2010-04-13 2013-02-20 Mahmut Bilgic Trockenpulverinhalator-mundstück
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
EP2630724A4 (de) 2010-10-18 2018-01-03 Accio Energy, Inc. System und verfahren zur steuerung elektrischer felder in elektro-hydrodynamischen anwendungen
EP2721036B1 (de) 2011-06-15 2015-07-22 Takeda GmbH Neuartige 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isochinolin-verbindungen
MX2013014888A (es) 2011-06-17 2014-02-27 Takeda Gmbh Novedosos derivados de ftalazinona-pirrolopirimidinacarboxamida.
JP5762872B2 (ja) 2011-07-29 2015-08-12 住友化学株式会社 静電噴霧装置
NL2008056C2 (en) * 2011-12-29 2013-07-03 Univ Delft Tech System and method for delivering sprayed particles by electrospraying.
AU2012337241B2 (en) 2011-12-30 2016-10-13 Grifols, S.A. Alpha1-proteinase inhibitor for delaying the onset or progression of pulmonary exacerbations
US9603906B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Inhalable liquid formulations of DNase I
US9993604B2 (en) 2012-04-27 2018-06-12 Covidien Lp Methods and systems for an optimized proportional assist ventilation
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
US9027552B2 (en) 2012-07-31 2015-05-12 Covidien Lp Ventilator-initiated prompt or setting regarding detection of asynchrony during ventilation
EP3650067A1 (de) * 2013-03-11 2020-05-13 John R. Collins Inhalatorvorrichtung und -verfahren
CN112891688A (zh) 2014-08-28 2021-06-04 诺顿(沃特福特)有限公司 吸入器的依从性辅助模块
US10589298B2 (en) 2014-09-04 2020-03-17 Victory Innovations Company Electrostatic fluid delivery system
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
DE102014017409B4 (de) * 2014-11-26 2016-06-09 Klaus Dieter Beller Einzeldosis-Pulverinhalator und Verfahren zu dessen Herstellung
RU2017125957A (ru) 2015-01-04 2019-02-04 Проталикс Лтд. Модифицированная днказа и ее применения
JP6384378B2 (ja) * 2015-03-25 2018-09-05 オムロンヘルスケア株式会社 超音波式ネブライザ
JP6112130B2 (ja) * 2015-03-25 2017-04-12 トヨタ自動車株式会社 静電ノズル、吐出装置及び半導体モジュールの製造方法
EP3393671B1 (de) 2015-12-21 2020-11-11 Victory Innovations Company Rucksacksystem für elektrostatische flüssigkeit
CN109475707A (zh) 2016-05-03 2019-03-15 精呼吸股份有限公司 用于输送流体到肺部系统的液滴输送装置及其使用方法
WO2018069210A1 (en) 2016-10-10 2018-04-19 Takeda Gmbh Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4
GB201617246D0 (en) * 2016-10-11 2016-11-23 British American Tobacco (Investments) Limited Aerosol provision system and method
WO2018195400A1 (en) * 2017-04-20 2018-10-25 Victory Innovations Company Electrostatic stem cell fluid delivery system
TWI615202B (zh) * 2017-04-26 2018-02-21 定量電灑噴霧裝置
WO2018197730A1 (en) * 2017-04-28 2018-11-01 Softhale Nv Inhalation device and method
CN110799231B (zh) 2017-05-19 2022-08-02 精呼吸股份有限公司 干粉输送装置及其使用方法
EP3634550A4 (de) 2017-06-10 2021-03-03 Eyenovia, Inc. Verfahren und vorrichtungen zur handhabung einer flüssigkeit und zur abgabe der flüssigkeit an das auge
ES2907567T3 (es) * 2017-06-22 2022-04-25 Softhale Nv Dispositivo de inhalación con boquilla multilíquido
RU2755024C2 (ru) * 2017-06-22 2021-09-09 Софтхейл Нв Сопло для различных жидкостей
CN111526914A (zh) 2017-10-04 2020-08-11 精呼吸股份有限公司 电子呼吸致动式直线型液滴输送装置及其使用方法
CA3079189A1 (en) 2017-10-17 2019-04-25 Pneuma Respiratory, Inc. Nasal drug delivery apparatus and methods of use
FR3072295B1 (fr) * 2017-10-18 2019-10-11 Aptar France Sas Dispositif de distribution de produit fluide synchronise avec l'inhalation.
CA3082192A1 (en) 2017-11-08 2019-05-16 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use
US20210077750A1 (en) * 2018-05-04 2021-03-18 Microbase Technology Corp. Microstructured nozzle
EP3860768B1 (de) * 2018-10-01 2024-05-22 Pneuma Respiratory, Inc. Abgabe von zusammensetzungen mit niedriger oberflächenspannung an das pulmonale system über eine elektronische atemzugbetriebene tröpfchenabgabevorrichtung
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
DE102019217933A1 (de) * 2019-11-21 2021-05-27 Robert Bosch Gmbh Sensormodul für eine Medikamentenabgabevorrichtung, Sensorvorrichtung mit einem Sensormodul und einem Adapter, Medikamentenabgabesystem mit einer Medikamentenabgabevorrichtung und einer Sensorvorrichtung und Verfahren zum Erkennen einer Medikamentenabgabevorrichtung
US20210283145A1 (en) 2020-03-13 2021-09-16 Softhale Nv Method for the treatment of viral infections
EP4121032A1 (de) 2020-03-19 2023-01-25 Softhale NV Verfahren zur behandlung von nlrp3-assoziierten erkrankungen
US20230142260A1 (en) 2020-03-31 2023-05-11 Softhale Nv Inhalation device system
US20210308047A1 (en) 2020-04-03 2021-10-07 Softhale Nv Methods of treatment using niclosamide
US11013688B1 (en) 2020-05-28 2021-05-25 Softhale Nv Methods of treatment of viral diseases
CN113171898A (zh) * 2021-05-11 2021-07-27 江苏苏美达五金工具有限公司 一种手持式静电雾化器
EP4359046A1 (de) 2021-06-22 2024-05-01 Pneuma Respiratory, Inc. Tröpfchenabgabevorrichtung mit schubausstoss
EP4373553A1 (de) 2021-07-20 2024-05-29 invoX Belgium NV Inhalationsvorrichtungssystem mit zähl- und blockieranordnung

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296491A (en) * 1961-09-19 1967-01-03 Martin M Decker Method and apparatus for producing ions and electrically-charged aerosols
AU531759B2 (en) * 1978-04-17 1983-09-08 Ici Ltd. Electrostatic spraying
US4228961A (en) * 1979-05-07 1980-10-21 Onoda Cement Co., Ltd. Electrostatic power painting head
EP0174033B1 (de) * 1984-09-07 1991-03-27 OMRON Corporation Schwingungserzeuger für ein Inhalationsgerät mit Ultraschallzerstäubung
GB8504253D0 (en) * 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
GB8609703D0 (en) * 1986-04-21 1986-05-29 Ici Plc Electrostatic spraying
US5511726A (en) * 1988-09-23 1996-04-30 Battelle Memorial Institute Nebulizer device
US4971257A (en) * 1989-11-27 1990-11-20 Marc Birge Electrostatic aerosol spray can assembly
DE4106564C2 (de) * 1991-03-01 1999-06-10 Bosch Gmbh Robert Vorrichtung zur elektrostatischen Zerstäubung von Flüssigkeiten
US5196171A (en) * 1991-03-11 1993-03-23 In-Vironmental Integrity, Inc. Electrostatic vapor/aerosol/air ion generator
WO1992017231A1 (en) * 1991-03-28 1992-10-15 Innomed, Inc. Microelectronic inhaler having a counter and timer
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
GB2272389B (en) * 1992-11-04 1996-07-24 Bespak Plc Dispensing apparatus
GB9226717D0 (en) * 1992-12-22 1993-02-17 Coffee Ronald A Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
US6105571A (en) * 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9303335D0 (en) * 1993-02-19 1993-04-07 Bespak Plc Inhalation apparatus
ES2171455T3 (es) * 1993-06-29 2002-09-16 Ponwell Entpr Ltd Dispensador.
US5567495A (en) * 1993-08-06 1996-10-22 The Trustees Of Columbia University In The City Of New York Infection resistant medical devices
CH686872A5 (de) * 1993-08-09 1996-07-31 Disetronic Ag Medizinisches Inhalationsgeraet.
CR4906A (es) * 1993-09-10 1994-09-09 Philip Morris Prod Sistema electrico de fumar para distribuir sabores y metodopara su fabricacion
GB9406171D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406255D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
US5564414A (en) * 1994-05-26 1996-10-15 Walker; William F. Pressurized and metered medication dose counter on removable sleeve
GB9410658D0 (en) * 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
GB9511514D0 (en) * 1995-06-07 1995-08-02 Ici Plc Electrostatic spraying
US5622163A (en) * 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
US5544647A (en) * 1994-11-29 1996-08-13 Iep Group, Inc. Metered dose inhalator
US5724986A (en) * 1995-11-06 1998-03-10 Jones Medical Instrument Co. Casing and spirometer for metered dose inhaler
US6116516A (en) * 1996-05-13 2000-09-12 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US5743251A (en) * 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
ATE263629T1 (de) * 1996-07-23 2004-04-15 Battelle Memorial Institute Vorrichtung zum spenden und verfahren zur formung eines materials
SE510741E (sv) * 1997-04-07 2008-03-28 Gibeck Ab Louis Anordning och förfarande för tillförsel av behandlingsgas till människa eller djur genom förgasning av behandlingsvätska
DE19720701A1 (de) * 1997-05-16 1998-11-19 Gsf Forschungszentrum Umwelt Vorrichtung zur Applikation eines Medikament-Aerosols über die Lunge
US6290685B1 (en) * 1998-06-18 2001-09-18 3M Innovative Properties Company Microchanneled active fluid transport devices
GB2327895B (en) * 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
US6158431A (en) * 1998-02-13 2000-12-12 Tsi Incorporated Portable systems and methods for delivery of therapeutic material to the pulmonary system
FR2776538B1 (fr) * 1998-03-27 2000-07-21 Centre Nat Rech Scient Moyens de pulverisation electrohydrodynamique
US6003794A (en) * 1998-08-04 1999-12-21 Progressive Grower Technologies, Inc. Electrostatic spray module
US6368079B2 (en) * 1998-12-23 2002-04-09 Battelle Pulmonary Therapeutics, Inc. Piezoelectric micropump
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
KR20020005721A (ko) * 1999-04-23 2002-01-17 추후기재 하이 매스 전달 전기분무기
KR20020003239A (ko) * 1999-04-23 2002-01-10 추후기재 방향제어식 수중방전충격 동적 에어러솔 분무기

Also Published As

Publication number Publication date
AU764814B2 (en) 2003-08-28
HK1043553A1 (zh) 2002-09-20
US20020153006A1 (en) 2002-10-24
JP4369062B2 (ja) 2009-11-18
WO2000038770A2 (en) 2000-07-06
BR9916533A (pt) 2001-12-11
EP1144033B1 (de) 2005-03-02
CA2355683C (en) 2010-01-12
EP1144033A3 (de) 2001-12-05
US20050236501A1 (en) 2005-10-27
ATE289835T1 (de) 2005-03-15
JP2003528644A (ja) 2003-09-30
EP1144033A2 (de) 2001-10-17
CA2355683A1 (en) 2000-07-06
US6796303B2 (en) 2004-09-28
US20050039738A1 (en) 2005-02-24
WO2000038770A3 (en) 2001-08-02
DE69924018T2 (de) 2006-04-13
US6397838B1 (en) 2002-06-04
CN1335783A (zh) 2002-02-13
AU2592900A (en) 2000-07-31
WO2000038770A9 (en) 2001-09-20
NZ512583A (en) 2003-10-31

Similar Documents

Publication Publication Date Title
DE69924018D1 (de) Vorrichtung und verfahren zum abgeben von lungenaerosolen
DE60024992D1 (de) Richtungsverstellbarer ehd- aerosol-zerstäuber
DK0482814T3 (da) Fluiddispenser med ensartet afgivelseshastighed
ATE40800T1 (de) Drehglockenspritzvorrichtung zum duennen beschichten von werkstuecken mit fluessigkeit und verfahren zu ihrer anwendung.
ES2196369T3 (es) Dispositivos dispensadores.
TW330846B (en) Electrostatic spraying device
FR2484621B1 (fr) Appareil et procede pour le conditionnement d'un courant de gaz, par exemple d'air alimentant des cabines de peinture au pistolet
DE59914385D1 (de) Vorrichtung zum erzeugen eines aerosols
DE60041610D1 (de) Gerät zum Abgeben von abgemessenen Mengen von Medikamente beinhaltendem Aerosol
ATE275989T1 (de) Vorrichtung zum verabreichen einer mischung aus zwei flüssigkomponenten
NO944156D0 (no) Forstövningsanordning
EA199800231A1 (ru) Сопло распылителя
DE69919855D1 (de) Vernebler und steuersystem für die vernebelung
DE69118524T2 (de) Vorrichtung zum kontrollierten Ausgeben von Stoffen aus verformbaren Tuben
NL1001682C2 (nl) Vernevelingsinrichting.
ATE102566T1 (de) Wiederfuellbarer zerstaeuber und vorrichtung zum wiederfuellen.
GB1305376A (de)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: VENTAIRA PHARMACEUTICALS, INC. (N. D. GES. D. , US