BR0010262A - Composição para formar um aerossol, processo de preparação e de aerossolização de uma composição, e, dispositivo gerador de aerossol - Google Patents
Composição para formar um aerossol, processo de preparação e de aerossolização de uma composição, e, dispositivo gerador de aerossolInfo
- Publication number
- BR0010262A BR0010262A BR0010262-8A BR0010262A BR0010262A BR 0010262 A BR0010262 A BR 0010262A BR 0010262 A BR0010262 A BR 0010262A BR 0010262 A BR0010262 A BR 0010262A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- aerosol
- active ingredient
- aerosolizing
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
Abstract
"COMPOSIçãO PARA FORMAR UM AEROSSOL PROCESSO DE PREPARAçãO E DE AEROSSOLIZAçãO DE UMA COMPOSIçãO, E, DISPOSITIVO GERADOR DE AEROSSOL". Uma composição usada em combinação com um dispositivo eletro-hidrodinâmico capaz de fornecer um ingrediente ativo ao sistema aerodigestivo do usuário. A composição compreende três ou opcionalmente quatro componentes básicos; um ingrediente ativo; um material veículo no qual o ingrediente ativo pode ser dissolvido, suspenso, ou emulsificado; um material ajustador de propriedades de aerossol que proporciona a composição com as características físicas requeridas para formar uma nuvem de aerossol por meio eletrostático ou eletro-hidrodinâmico; e opcionalmente pelo menos um excipiente que adicionalmente ajusta, conserva, estabiliza, ou intensifica o desempenho da composição.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13221599P | 1999-05-03 | 1999-05-03 | |
PCT/US2000/011799 WO2000066206A2 (en) | 1999-05-03 | 2000-05-02 | Compositions for aerosolization and inhalation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0010262A true BR0010262A (pt) | 2002-01-15 |
Family
ID=22453000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0010262-8A BR0010262A (pt) | 1999-05-03 | 2000-05-02 | Composição para formar um aerossol, processo de preparação e de aerossolização de uma composição, e, dispositivo gerador de aerossol |
Country Status (11)
Country | Link |
---|---|
US (1) | US6503481B1 (pt) |
EP (1) | EP1173245B1 (pt) |
JP (1) | JP2002543165A (pt) |
AT (1) | ATE274955T1 (pt) |
AU (1) | AU4979700A (pt) |
BR (1) | BR0010262A (pt) |
CA (1) | CA2370853C (pt) |
DE (1) | DE60013425T2 (pt) |
ES (1) | ES2226843T3 (pt) |
MX (1) | MXPA01011283A (pt) |
WO (1) | WO2000066206A2 (pt) |
Families Citing this family (69)
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GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
AU2001226029A1 (en) * | 2000-01-10 | 2001-07-24 | Dura Pharmaceuticals, Inc. | Pharmaceutical formulation and method for pulmonary and oral delivery |
BR0108077A (pt) * | 2000-02-04 | 2002-10-22 | Children S Hospital Res Founda | Processo para reduzir placas ateroscleróticas em um mamìfero, método para tratamento da aterosclerose em um mamìfero, composição, métodos para prover proteìna ou polipeptìdeo hidrolisante de lipìdeo biologicamente ativo ou mistura deles, para células de um mamìfero tendo deficiência na proteìna ou polipeptìdeo hidrolisante de lipìdeo biologicamente ativo , para prover lipase de ácido lisossomal biologicamente ativa para células de um mamìfero tendo deficiência de lipase de ácido lisossomal biologicamente ativa, para prover lipase de ácido lisossoal biologicamente ativa para células de um mamìfero com aterosclerose, para tratamento da doença de wolman em um mamìfero, para tratamento de doença de armazenagem de colesteril éster em um mamìfero, e, para tratamento da aterosclerose em um mamìfero |
CA2405169C (en) | 2000-04-03 | 2011-07-26 | Battelle Memorial Institute | Devices and formulations |
JP2004526674A (ja) * | 2000-12-01 | 2004-09-02 | バテル・メモリアル・インスティテュート | 液体処方物中における生体分子の安定化のための方法 |
EP1370238B1 (en) | 2001-03-22 | 2008-11-12 | Battelle Memorial Institute | Liquid formulations for electrohydrodynamic spraying containing polymer and suspended particles |
US6737042B2 (en) | 2001-05-24 | 2004-05-18 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
US7078016B2 (en) | 2001-11-21 | 2006-07-18 | Alexza Pharmaceuticals, Inc. | Delivery of caffeine through an inhalation route |
DE60230035D1 (de) | 2001-05-24 | 2009-01-08 | Alexza Pharmaceuticals Inc | Verabreichung von alprazolam, estazolam, midazolam oder triazolam durch inhalation |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
WO2002094242A1 (en) | 2001-05-24 | 2002-11-28 | Alexza Molecular Delivery Corporation | Delivery of rizatriptan or zolmitriptan through an inhalation route |
US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
AU2002368202B2 (en) | 2001-11-02 | 2008-06-05 | Insert Therapeutics, Inc | Methods and compositions for therapeutic use of RNA interference |
WO2003041693A1 (en) | 2001-11-09 | 2003-05-22 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
US7842310B2 (en) * | 2001-11-19 | 2010-11-30 | Becton, Dickinson And Company | Pharmaceutical compositions in particulate form |
EP2098113A3 (en) | 2002-10-25 | 2010-12-29 | Battelle Memorial Institute | Electrohydrodynamic spray for treating non-human animals |
US7849850B2 (en) * | 2003-02-28 | 2010-12-14 | Battelle Memorial Institute | Nozzle for handheld pulmonary aerosol delivery device |
US20040187864A1 (en) * | 2003-03-24 | 2004-09-30 | Cindet, Llc | Inhalation device and method |
WO2004104490A1 (en) | 2003-05-21 | 2004-12-02 | Alexza Pharmaceuticals, Inc. | Self-contained heating unit and drug-supply unit employing same |
FR2855069B1 (fr) * | 2003-05-22 | 2006-06-16 | Solvay | Procede pour la separation d'au moins un compose organique |
ATE364402T1 (de) * | 2004-03-10 | 2007-07-15 | Shimoda Biotech Pty Ltd | Stabile injizierbare diclofenac- zubereitungen |
KR20050099311A (ko) * | 2004-04-09 | 2005-10-13 | 에이엔에이치 케어연구소(주) | 주사제용 항암제 조성물 |
MXPA06012240A (es) | 2004-04-23 | 2007-01-31 | Cydex Inc | Formulacion para inhalador de polvo seco que contiene eter sulfoalquilico-ciclodextrina. |
AU2005247410A1 (en) * | 2004-05-20 | 2005-12-08 | Discovery Laboratories, Inc. | Methods , systems and devices for noninvasive pulmonary delivery |
AU2005284706B2 (en) * | 2004-09-14 | 2011-02-24 | Battelle Memorial Institute | Highly-aqueous non-respirable aerosols containing biologically-active ingredients method of making and device therefor |
CA2603730A1 (en) | 2005-03-31 | 2006-10-05 | Calando Pharmaceuticals, Inc. | Inhibitors of ribonucleotide reductase subunit 2 and uses thereof |
US8028697B2 (en) | 2005-04-28 | 2011-10-04 | Trudell Medical International | Ventilator circuit and method for the use thereof |
CN102327285A (zh) * | 2005-05-18 | 2012-01-25 | 普马特里克斯公司 | 改变粘膜内衬生物物理特性的配方 |
WO2007030375A2 (en) * | 2005-09-08 | 2007-03-15 | Children's Hospital Medical Center | Lysosomal acid lipase therapy for nafld and related diseases |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
AU2006308716A1 (en) | 2005-11-01 | 2007-05-10 | Alnylam Pharmaceuticals, Inc. | RNAi inhibition of influenza virus replication |
WO2007083164A2 (en) * | 2006-01-17 | 2007-07-26 | Aerstream Technology Limited | Liquid electrostatic spray composition |
US7931020B2 (en) | 2006-02-14 | 2011-04-26 | Battelle Memorial Institute | Dissociated discharge EHD sprayer with electric field shield |
WO2007109097A2 (en) | 2006-03-16 | 2007-09-27 | Alnylam Pharmaceuticals, Inc. | RNAi MODULATION OF TGF-BETA AND THERAPEUTIC USES THEREOF |
JP2007254421A (ja) * | 2006-03-24 | 2007-10-04 | Canon Inc | 吐出用液体、吐出方法、吐出用カートリッジ、吐出装置及び吐出用液体の液滴化方法 |
AU2007253803B2 (en) | 2006-05-19 | 2012-05-24 | Alnylam Pharmaceuticals, Inc. | RNAi modulation of Aha and therapeutic uses thereof |
US20090054333A1 (en) * | 2006-10-17 | 2009-02-26 | Antonio Giordano | Peptide inhibitors of cyclin-dependent kinase activity and uses thereof |
US20100143264A1 (en) * | 2007-02-01 | 2010-06-10 | Battelle Memorial Institute | Compositions for aerosolization of highly conductive solutions |
WO2008106646A2 (en) * | 2007-03-01 | 2008-09-04 | Introgen Therapeutics, Inc | Methods and formulations for topical gene therapy |
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ES2565219T3 (es) * | 2008-03-17 | 2016-04-01 | Discovery Laboratories, Inc. | Adaptador de circuito de ventilación y sistema proximal de administración de aerosol |
CN102037123A (zh) | 2008-04-04 | 2011-04-27 | 卡兰多制药股份有限公司 | Epas1抑制剂的组合物和用途 |
CA2683353C (en) | 2008-10-22 | 2015-12-15 | Trudell Medical International | Modular aerosol delivery system |
KR20120093066A (ko) | 2009-05-29 | 2012-08-22 | 스미또모 가가꾸 가부시키가이샤 | 신경영양인자의 활성이 관여하는 질환의 치료 또는 예방제 |
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EP2611438B1 (en) | 2010-08-30 | 2020-04-01 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
EP2448571B1 (en) | 2010-08-30 | 2013-06-12 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
KR101915241B1 (ko) | 2010-09-29 | 2018-11-06 | 풀매트릭스 오퍼레이팅 컴퍼니, 인크 | 흡입용의 1가 금속 양이온 건조 분말 |
EP2621488B1 (en) | 2010-09-29 | 2018-11-07 | Pulmatrix Operating Company, Inc. | Cationic dry powders |
WO2012090683A1 (en) * | 2010-12-28 | 2012-07-05 | Sumitomo Chemical Company, Limited | Method of treating target space, and liquid particles |
AU2011265562A1 (en) | 2011-01-12 | 2012-07-26 | Sumitomo Chemical Company, Limited | Method of controlling harmful arthropod, composition, and electrostatic spray device |
US20120302954A1 (en) * | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
JP2013070767A (ja) * | 2011-09-27 | 2013-04-22 | Panasonic Corp | 機能性微粒子放出装置 |
US9089529B2 (en) | 2011-10-25 | 2015-07-28 | Prothena Therapeutics Limited | Antibody formulations and methods |
NZ629722A (en) | 2012-02-29 | 2017-03-31 | Pulmatrix Operating Co Inc | Inhalable dry powders |
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US9802010B2 (en) * | 2013-11-22 | 2017-10-31 | Noveome Biotherapeutics, Inc. | Interproximal drug delivery device |
JP2017505348A (ja) | 2014-02-10 | 2017-02-16 | パタラ ファーマ リミテッド ライアビリティ カンパニー | 肺疾患治療のための肥満細胞安定剤 |
EP3653207A1 (en) | 2014-02-10 | 2020-05-20 | Respivant Sciences GmbH | Mast cell stabilizers treatment for systemic disorders |
SG11201700484SA (en) * | 2014-08-08 | 2017-02-27 | Shenzhen Hightide Biopharmaceutical Ltd | Liquid formulation compositions, medicament delivery devices, and methods of preparation and use thereof |
CN114522152A (zh) | 2015-03-11 | 2022-05-24 | 艾利斯达医药品公司 | 气道中的防静电材料用于热气溶胶凝结方法的用途 |
GB201509820D0 (en) * | 2015-05-06 | 2015-07-22 | Nicoventures Holdings Ltd | Aerosol delivery device |
WO2017027402A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
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WO2018044942A1 (en) | 2016-08-31 | 2018-03-08 | Patara Pharma, LLC | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
AU2017339366A1 (en) | 2016-10-07 | 2019-04-11 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of pulmonary fibrosis |
CA3210753A1 (en) | 2021-02-09 | 2022-08-18 | University Of Georgia Research Foundation, Inc. | Human monoclonal antibodies against pneumococcal antigens |
WO2023198757A1 (en) | 2022-04-14 | 2023-10-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Alpha-1-antitrypsin for treating paramyxoviridae or orthomyxoviridae infections |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4659012A (en) | 1983-08-18 | 1987-04-21 | Imperial Chemical Industries Plc | Electrostatic spraying process and apparatus |
GB8604328D0 (en) * | 1986-02-21 | 1986-03-26 | Ici Plc | Producing spray of droplets of liquid |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
GB9226717D0 (en) | 1992-12-22 | 1993-02-17 | Coffee Ronald A | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
US6105571A (en) | 1992-12-22 | 2000-08-22 | Electrosols, Ltd. | Dispensing device |
US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
GB9406255D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
GB2327895B (en) | 1997-08-08 | 2001-08-08 | Electrosols Ltd | A dispensing device |
US6158431A (en) | 1998-02-13 | 2000-12-12 | Tsi Incorporated | Portable systems and methods for delivery of therapeutic material to the pulmonary system |
GB2334461B (en) | 1998-02-20 | 2002-01-23 | Bespak Plc | Inhalation apparatus |
FR2776538B1 (fr) | 1998-03-27 | 2000-07-21 | Centre Nat Rech Scient | Moyens de pulverisation electrohydrodynamique |
GB2345010B (en) | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
US6397838B1 (en) | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
-
2000
- 2000-05-02 WO PCT/US2000/011799 patent/WO2000066206A2/en active IP Right Grant
- 2000-05-02 CA CA002370853A patent/CA2370853C/en not_active Expired - Fee Related
- 2000-05-02 MX MXPA01011283A patent/MXPA01011283A/es active IP Right Grant
- 2000-05-02 DE DE60013425T patent/DE60013425T2/de not_active Expired - Lifetime
- 2000-05-02 EP EP00932001A patent/EP1173245B1/en not_active Expired - Lifetime
- 2000-05-02 AT AT00932001T patent/ATE274955T1/de not_active IP Right Cessation
- 2000-05-02 JP JP2000615088A patent/JP2002543165A/ja active Pending
- 2000-05-02 ES ES00932001T patent/ES2226843T3/es not_active Expired - Lifetime
- 2000-05-02 US US09/561,648 patent/US6503481B1/en not_active Expired - Fee Related
- 2000-05-02 BR BR0010262-8A patent/BR0010262A/pt not_active IP Right Cessation
- 2000-05-02 AU AU49797/00A patent/AU4979700A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2226843T3 (es) | 2005-04-01 |
US6503481B1 (en) | 2003-01-07 |
AU4979700A (en) | 2000-11-17 |
CA2370853A1 (en) | 2000-11-09 |
WO2000066206A2 (en) | 2000-11-09 |
DE60013425D1 (de) | 2004-10-07 |
ATE274955T1 (de) | 2004-09-15 |
WO2000066206A3 (en) | 2001-02-08 |
DE60013425T2 (de) | 2005-09-08 |
MXPA01011283A (es) | 2002-11-04 |
CA2370853C (en) | 2007-07-10 |
JP2002543165A (ja) | 2002-12-17 |
EP1173245A2 (en) | 2002-01-23 |
EP1173245B1 (en) | 2004-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007. |