DE60013425D1 - Arzneizusammensetzungen zur aerosolbildung und zu inhalationszwecken - Google Patents
Arzneizusammensetzungen zur aerosolbildung und zu inhalationszweckenInfo
- Publication number
- DE60013425D1 DE60013425D1 DE60013425T DE60013425T DE60013425D1 DE 60013425 D1 DE60013425 D1 DE 60013425D1 DE 60013425 T DE60013425 T DE 60013425T DE 60013425 T DE60013425 T DE 60013425T DE 60013425 D1 DE60013425 D1 DE 60013425D1
- Authority
- DE
- Germany
- Prior art keywords
- composition
- active ingredient
- aerosol formation
- medical compositions
- inhalation purposes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13221599P | 1999-05-03 | 1999-05-03 | |
US132215P | 1999-05-03 | ||
PCT/US2000/011799 WO2000066206A2 (en) | 1999-05-03 | 2000-05-02 | Compositions for aerosolization and inhalation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60013425D1 true DE60013425D1 (de) | 2004-10-07 |
DE60013425T2 DE60013425T2 (de) | 2005-09-08 |
Family
ID=22453000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60013425T Expired - Lifetime DE60013425T2 (de) | 1999-05-03 | 2000-05-02 | Arzneizusammensetzungen zur aerosolbildung und zu inhalationszwecken |
Country Status (11)
Country | Link |
---|---|
US (1) | US6503481B1 (de) |
EP (1) | EP1173245B1 (de) |
JP (1) | JP2002543165A (de) |
AT (1) | ATE274955T1 (de) |
AU (1) | AU4979700A (de) |
BR (1) | BR0010262A (de) |
CA (1) | CA2370853C (de) |
DE (1) | DE60013425T2 (de) |
ES (1) | ES2226843T3 (de) |
MX (1) | MXPA01011283A (de) |
WO (1) | WO2000066206A2 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
AU2001226029A1 (en) * | 2000-01-10 | 2001-07-24 | Dura Pharmaceuticals, Inc. | Pharmaceutical formulation and method for pulmonary and oral delivery |
JP2003523330A (ja) * | 2000-02-04 | 2003-08-05 | チルドレンズ・ホスピタル・リサーチ・ファウンデイション | アテローム性動脈硬化症および関連疾患のための脂質加水分解治療 |
CA2405169C (en) * | 2000-04-03 | 2011-07-26 | Battelle Memorial Institute | Devices and formulations |
EP1343521A2 (de) * | 2000-12-01 | 2003-09-17 | Battelle Memorial Institute | Verfahren zur stabilisierung von biomolekülen (z.b. insulin) in flüssigen formulierungen |
JP2005501810A (ja) * | 2001-03-22 | 2005-01-20 | バテル メモリアル インスティチュート | ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物 |
DE60230035D1 (de) | 2001-05-24 | 2009-01-08 | Alexza Pharmaceuticals Inc | Verabreichung von alprazolam, estazolam, midazolam oder triazolam durch inhalation |
US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
CA2446904A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
US6759029B2 (en) | 2001-05-24 | 2004-07-06 | Alexza Molecular Delivery Corporation | Delivery of rizatriptan and zolmitriptan through an inhalation route |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US7078016B2 (en) | 2001-11-21 | 2006-07-18 | Alexza Pharmaceuticals, Inc. | Delivery of caffeine through an inhalation route |
CA2465860A1 (en) | 2001-11-02 | 2004-04-22 | Insert Therapeutics, Inc. | Methods and compositions for therapeutic use of rna interference |
WO2003041693A1 (en) | 2001-11-09 | 2003-05-22 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
MXPA04004726A (es) * | 2001-11-19 | 2004-07-30 | Becton Dickinson Co | Composiciones farmaceuticas en forma particulada. |
DE60330805D1 (de) | 2002-10-25 | 2010-02-11 | Battelle Memorial Institute | Verfahren zur nichttherapeutischen behandlung von nichtmenschlichen tieren |
US7849850B2 (en) * | 2003-02-28 | 2010-12-14 | Battelle Memorial Institute | Nozzle for handheld pulmonary aerosol delivery device |
US20040187864A1 (en) * | 2003-03-24 | 2004-09-30 | Cindet, Llc | Inhalation device and method |
EP1625335A2 (de) | 2003-05-21 | 2006-02-15 | Alexza Pharmaceuticals, Inc. | Optisch oder elektrisch gezündete unabhängige heizeinheit und diese einsetzende arzneimittelzufuhreinheit |
FR2855069B1 (fr) * | 2003-05-22 | 2006-06-16 | Solvay | Procede pour la separation d'au moins un compose organique |
PT1767219E (pt) * | 2004-03-10 | 2010-02-15 | Shimoda Biotech Pty Ltd | Composições injectáveis estáveis de diclofenac |
KR20050099311A (ko) * | 2004-04-09 | 2005-10-13 | 에이엔에이치 케어연구소(주) | 주사제용 항암제 조성물 |
CA2562585A1 (en) | 2004-04-23 | 2005-11-10 | Cydex, Inc. | Dpi formulation containing sulfoalkyl ether cyclodextrin |
AU2005247410A1 (en) * | 2004-05-20 | 2005-12-08 | Discovery Laboratories, Inc. | Methods , systems and devices for noninvasive pulmonary delivery |
US20080259519A1 (en) * | 2004-09-14 | 2008-10-23 | Battelle Memorial Institute | Highly-Aqueous, Non-Respirable Aerosols Containing Biologically-Active Ingredients, Method of Making, and Device Therefor |
PL1866414T3 (pl) | 2005-03-31 | 2012-10-31 | Calando Pharmaceuticals Inc | Inhibitory podjednostki 2 reduktazy rybonukleotydowej i ich zastosowania |
US8028697B2 (en) | 2005-04-28 | 2011-10-04 | Trudell Medical International | Ventilator circuit and method for the use thereof |
EP1906922A2 (de) * | 2005-05-18 | 2008-04-09 | Pulmatrix, Inc. | Formulierungen zur veränderung biophysikalischer eigenschaften der schleimhautauskleidung |
US20090297496A1 (en) * | 2005-09-08 | 2009-12-03 | Childrens Hospital Medical Center | Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
BRPI0618214A2 (pt) | 2005-11-01 | 2011-08-23 | Alnylam Pharmaceuticals Inc | inibição de rnai de replicação do influenza vìrus |
WO2007083164A2 (en) * | 2006-01-17 | 2007-07-26 | Aerstream Technology Limited | Liquid electrostatic spray composition |
AU2006338191B2 (en) | 2006-02-14 | 2011-06-30 | Battelle Memorial Institute | Dissociated discharge EHD sprayer with electric field shield |
EP1993611A4 (de) | 2006-03-16 | 2013-05-22 | Alnylam Pharmaceuticals Inc | Rnai-modulation von tgf-beta und ihre therapeutische verwendung |
JP2007254421A (ja) * | 2006-03-24 | 2007-10-04 | Canon Inc | 吐出用液体、吐出方法、吐出用カートリッジ、吐出装置及び吐出用液体の液滴化方法 |
CN101489566B (zh) | 2006-05-19 | 2012-04-18 | 阿尔尼拉姆医药品有限公司 | Aha基因的RNAi调控及其治疗性应用 |
US20090054333A1 (en) * | 2006-10-17 | 2009-02-26 | Antonio Giordano | Peptide inhibitors of cyclin-dependent kinase activity and uses thereof |
EP2117507A2 (de) * | 2007-02-01 | 2009-11-18 | Battelle Memorial Institute | Zusammensetzungen zur aerosolisierung hoch leitfähiger lösungen |
US20080299182A1 (en) * | 2007-03-01 | 2008-12-04 | Shuyuan Zhang | Methods and formulations for topical gene therapy |
WO2008112661A2 (en) | 2007-03-09 | 2008-09-18 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
HUE028653T2 (en) | 2008-03-17 | 2016-12-28 | Discovery Lab Inc | Respiratory circuit adapter and direct aerosol delivery system |
CN102037123A (zh) | 2008-04-04 | 2011-04-27 | 卡兰多制药股份有限公司 | Epas1抑制剂的组合物和用途 |
CA2683353C (en) | 2008-10-22 | 2015-12-15 | Trudell Medical International | Modular aerosol delivery system |
WO2010137349A1 (ja) | 2009-05-29 | 2010-12-02 | 住友化学株式会社 | 神経栄養因子の活性が関与する疾患の治療または予防剤 |
US20110174304A1 (en) | 2010-01-21 | 2011-07-21 | Triplett Ii Michael D | Electrohydrodynamic aerosolization device having a time varying voltage |
US20120048963A1 (en) | 2010-08-26 | 2012-03-01 | Alexza Pharmaceuticals, Inc. | Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter |
AU2011296343B2 (en) | 2010-08-30 | 2015-12-10 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
WO2012030647A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
CA2812414C (en) | 2010-09-29 | 2020-09-22 | Pulmatrix, Inc. | Monovalent metal cation dry powders for inhalation |
WO2012050945A1 (en) | 2010-09-29 | 2012-04-19 | Pulmatrix, Inc. | Cationic dry powders |
BR112013018746B1 (pt) * | 2010-12-28 | 2019-03-19 | Sumitomo Chemical Company, Limited | Método de tratamento do espaço-alvo |
AU2011265562A1 (en) | 2011-01-12 | 2012-07-26 | Sumitomo Chemical Company, Limited | Method of controlling harmful arthropod, composition, and electrostatic spray device |
US20120302954A1 (en) * | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
JP2013070767A (ja) * | 2011-09-27 | 2013-04-22 | Panasonic Corp | 機能性微粒子放出装置 |
SG10201604104PA (en) | 2011-10-25 | 2016-07-28 | Prothena Therapeutics Ltd | Antibody formulations and methods |
CN104487075A (zh) | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
MX2015013845A (es) | 2013-04-01 | 2016-05-09 | Pulmatrix Inc | Polvos secos de tiotropio. |
US9802010B2 (en) * | 2013-11-22 | 2017-10-31 | Noveome Biotherapeutics, Inc. | Interproximal drug delivery device |
EP3725311A1 (de) | 2014-02-10 | 2020-10-21 | Respivant Sciences GmbH | Verfahren zur behandlung von lungenerkrankungen mit mastzellstabilisatoren |
US20150224077A1 (en) | 2014-02-10 | 2015-08-13 | Patara Pharma, LLC | Methods for the Treatment of Systemic Disorders Treatable with Mast Cell Stabilizers, including Mast Cell Related Disorders |
BR112017002356A2 (pt) * | 2014-08-08 | 2017-11-28 | Shanghai Hightide Biopharmaceutical Ltd | composições de formulação líquida, dispositivos de entrega de medicamento e métodos para preparação e uso dos mesmos |
KR102581975B1 (ko) | 2015-03-11 | 2023-09-25 | 알렉스자 파마스티칼즈, 인크. | 열 에어로졸 응축 공정을 위한 에어웨이에서 대전방지 소재의 용도 |
GB201509820D0 (en) * | 2015-05-06 | 2015-07-22 | Nicoventures Holdings Ltd | Aerosol delivery device |
EP3331522A1 (de) | 2015-08-07 | 2018-06-13 | Patara Pharma LLC | Verfahren zur behandlung von mastzellbedingten erkrankungen mit mastzellstabilisatoren |
WO2017027402A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
CA3035528A1 (en) | 2016-08-31 | 2018-03-08 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
JP2019531308A (ja) | 2016-10-07 | 2019-10-31 | レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh | 肺線維症の治療のためのクロモリン組成物 |
WO2022173689A1 (en) | 2021-02-09 | 2022-08-18 | University Of Georgia Research Foundation, Inc. | Human monoclonal antibodies against pneumococcal antigens |
WO2023198757A1 (en) | 2022-04-14 | 2023-10-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Alpha-1-antitrypsin for treating paramyxoviridae or orthomyxoviridae infections |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0152446B1 (de) | 1983-08-18 | 1988-12-21 | Imperial Chemical Industries Plc | Elektrostatisches zerstäubungsverfahren und vorrichtung zu dessen durchführung |
GB8604328D0 (en) | 1986-02-21 | 1986-03-26 | Ici Plc | Producing spray of droplets of liquid |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
US6105571A (en) | 1992-12-22 | 2000-08-22 | Electrosols, Ltd. | Dispensing device |
GB9226717D0 (en) | 1992-12-22 | 1993-02-17 | Coffee Ronald A | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
GB9406255D0 (en) * | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
GB2327895B (en) | 1997-08-08 | 2001-08-08 | Electrosols Ltd | A dispensing device |
US6158431A (en) | 1998-02-13 | 2000-12-12 | Tsi Incorporated | Portable systems and methods for delivery of therapeutic material to the pulmonary system |
GB2334461B (en) * | 1998-02-20 | 2002-01-23 | Bespak Plc | Inhalation apparatus |
FR2776538B1 (fr) * | 1998-03-27 | 2000-07-21 | Centre Nat Rech Scient | Moyens de pulverisation electrohydrodynamique |
GB2345010B (en) | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
US6397838B1 (en) * | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
-
2000
- 2000-05-02 BR BR0010262-8A patent/BR0010262A/pt not_active IP Right Cessation
- 2000-05-02 JP JP2000615088A patent/JP2002543165A/ja active Pending
- 2000-05-02 WO PCT/US2000/011799 patent/WO2000066206A2/en active IP Right Grant
- 2000-05-02 EP EP00932001A patent/EP1173245B1/de not_active Expired - Lifetime
- 2000-05-02 US US09/561,648 patent/US6503481B1/en not_active Expired - Fee Related
- 2000-05-02 CA CA002370853A patent/CA2370853C/en not_active Expired - Fee Related
- 2000-05-02 DE DE60013425T patent/DE60013425T2/de not_active Expired - Lifetime
- 2000-05-02 AU AU49797/00A patent/AU4979700A/en not_active Abandoned
- 2000-05-02 MX MXPA01011283A patent/MXPA01011283A/es active IP Right Grant
- 2000-05-02 ES ES00932001T patent/ES2226843T3/es not_active Expired - Lifetime
- 2000-05-02 AT AT00932001T patent/ATE274955T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1173245B1 (de) | 2004-09-01 |
WO2000066206A3 (en) | 2001-02-08 |
CA2370853C (en) | 2007-07-10 |
DE60013425T2 (de) | 2005-09-08 |
US6503481B1 (en) | 2003-01-07 |
ATE274955T1 (de) | 2004-09-15 |
AU4979700A (en) | 2000-11-17 |
EP1173245A2 (de) | 2002-01-23 |
JP2002543165A (ja) | 2002-12-17 |
WO2000066206A2 (en) | 2000-11-09 |
CA2370853A1 (en) | 2000-11-09 |
MXPA01011283A (es) | 2002-11-04 |
ES2226843T3 (es) | 2005-04-01 |
BR0010262A (pt) | 2002-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |