DE69922933T2 - Anwendungen für humane nicht autologe, mesenchymale stammzellen - Google Patents

Anwendungen für humane nicht autologe, mesenchymale stammzellen Download PDF

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Publication number
DE69922933T2
DE69922933T2 DE69922933T DE69922933T DE69922933T2 DE 69922933 T2 DE69922933 T2 DE 69922933T2 DE 69922933 T DE69922933 T DE 69922933T DE 69922933 T DE69922933 T DE 69922933T DE 69922933 T2 DE69922933 T2 DE 69922933T2
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Germany
Prior art keywords
mesenchymal stem
stem cells
cells
use according
allogeneic
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69922933T
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German (de)
English (en)
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DE69922933D1 (de
Inventor
P. Scott BRUDER
R. Kevin McINTOSH
R. Daniel MARSHAK
D. Joseph MOSCA
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Osiris Therapeutics Inc
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Osiris Therapeutics Inc
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Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
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Publication of DE69922933D1 publication Critical patent/DE69922933D1/de
Publication of DE69922933T2 publication Critical patent/DE69922933T2/de
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69922933T 1998-03-13 1999-03-12 Anwendungen für humane nicht autologe, mesenchymale stammzellen Expired - Lifetime DE69922933T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3912798A 1998-03-13 1998-03-13
US39127 1998-03-13
PCT/US1999/005351 WO1999046366A1 (en) 1998-03-13 1999-03-12 Uses for humane non-autologous mesenchymal stem cells

Publications (2)

Publication Number Publication Date
DE69922933D1 DE69922933D1 (de) 2005-02-03
DE69922933T2 true DE69922933T2 (de) 2005-12-29

Family

ID=21903827

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69922933T Expired - Lifetime DE69922933T2 (de) 1998-03-13 1999-03-12 Anwendungen für humane nicht autologe, mesenchymale stammzellen

Country Status (10)

Country Link
US (2) US6355239B1 (https=)
EP (1) EP1062321B1 (https=)
JP (1) JP4441115B2 (https=)
AT (1) ATE286118T1 (https=)
AU (1) AU749675B2 (https=)
CA (1) CA2323073C (https=)
DE (1) DE69922933T2 (https=)
ES (1) ES2237089T3 (https=)
PT (1) PT1062321E (https=)
WO (1) WO1999046366A1 (https=)

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* Cited by examiner, † Cited by third party
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