HUE059011T2 - Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek - Google Patents

Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek

Info

Publication number
HUE059011T2
HUE059011T2 HUE14168199A HUE14168199A HUE059011T2 HU E059011 T2 HUE059011 T2 HU E059011T2 HU E14168199 A HUE14168199 A HU E14168199A HU E14168199 A HUE14168199 A HU E14168199A HU E059011 T2 HUE059011 T2 HU E059011T2
Authority
HU
Hungary
Prior art keywords
abc5
immunomodulators
stem cells
mesenchymal stem
positive mesenchymal
Prior art date
Application number
HUE14168199A
Other languages
English (en)
Inventor
Markus Frank
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Publication of HUE059011T2 publication Critical patent/HUE059011T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HUE14168199A 2006-05-31 2007-05-31 Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek HUE059011T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80940706P 2006-05-31 2006-05-31

Publications (1)

Publication Number Publication Date
HUE059011T2 true HUE059011T2 (hu) 2022-09-28

Family

ID=38594403

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14168199A HUE059011T2 (hu) 2006-05-31 2007-05-31 Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek

Country Status (13)

Country Link
US (4) US8455245B2 (hu)
EP (2) EP2772535B1 (hu)
AU (1) AU2007254894B9 (hu)
CA (1) CA2685492C (hu)
DK (2) DK2772535T3 (hu)
ES (2) ES2918323T3 (hu)
HK (2) HK1129703A1 (hu)
HU (1) HUE059011T2 (hu)
LT (1) LT2772535T (hu)
PL (2) PL2035549T3 (hu)
PT (2) PT2035549E (hu)
SI (2) SI2035549T1 (hu)
WO (1) WO2007143139A1 (hu)

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ATE452909T1 (de) * 2000-06-05 2010-01-15 Brigham & Womens Hospital Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p- glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür
EP2772535B1 (en) 2006-05-31 2022-04-06 Children's Medical Center Corporation ABC5 positive mesenchymal stem cells as immunomodulators
EP3431103B1 (en) 2007-04-12 2021-07-28 The Brigham and Women's Hospital, Inc. Targeting abcb5 for cancer therapy
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
EP3130923B1 (en) 2008-11-14 2020-02-12 The Brigham and Women's Hospital, Inc. Therapeutic methods relating to cancer stem cells
CA2901931C (en) * 2013-02-19 2023-03-07 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
EP2994173B1 (en) 2013-05-10 2021-07-07 Children's Medical Center Corporation Wound healing and tissue engineering
US20150310380A1 (en) * 2014-04-28 2015-10-29 Patent Investment & Licensing Company Dispatch system having control shared with dispatched service providers
KR101723265B1 (ko) * 2013-08-16 2017-04-04 가톨릭대학교 산학협력단 mTOR/STAT3 신호억제제 처리된 면역조절능을 갖는 간엽줄기세포 및 이를 포함하는 면역질환의 예방 또는 치료용 세포치료제 조성물
PT3091991T (pt) * 2013-12-13 2020-02-04 Swedish Stromabio Ab Composições imunomodulatórias
WO2015148512A1 (en) 2014-03-24 2015-10-01 Qt Holdings Corp Shaped articles including hydrogels and methods of manufacture and use thereof
US9790467B2 (en) * 2015-09-22 2017-10-17 Qt Holdings Corp Methods and compositions for activation or expansion of T lymphocytes
US20210180087A1 (en) * 2018-08-18 2021-06-17 President And Fellows Of Harvard College In situ gene editing
US20200061365A1 (en) * 2018-08-24 2020-02-27 Instant Systems, Inc. Cell storage container for use with sterile docking systems
BR112021019349A2 (pt) * 2019-03-28 2021-12-07 Childrens Medical Center Células-tronco preparadas altamente funcionais
US20220241339A1 (en) * 2019-04-24 2022-08-04 Children's Medical Center Corporation Abcb5+ stem cell therapeutics for liver disease
US20230148432A1 (en) * 2020-03-30 2023-05-11 Children's Medical Center Corporation Use of stem cells for treatment of excessive inflammation
CN117835994A (zh) * 2021-05-13 2024-04-05 普干基因美国有限公司 用于治疗肝病的方法和组合物
US20230256065A1 (en) * 2022-02-16 2023-08-17 Elena RUSYN Autologous stem cell vaccine and methods
CN115260098A (zh) * 2022-06-09 2022-11-01 澳门科技大学 Abcb5抑制剂在制备多耐药性类风湿性关节炎治疗药物中的应用

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US4837306A (en) 1985-02-25 1989-06-06 The Ontario Cancer Institute Method for selecting hybridomas producing antibodies specific to the P-glycoprotein cell suface antigen and a cDNA clone encoding the C-terminal portion of the antigen
US5837258A (en) 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
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EP3130923B1 (en) 2008-11-14 2020-02-12 The Brigham and Women's Hospital, Inc. Therapeutic methods relating to cancer stem cells
CA2901931C (en) 2013-02-19 2023-03-07 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
EP2994173B1 (en) 2013-05-10 2021-07-07 Children's Medical Center Corporation Wound healing and tissue engineering
SG11202010260XA (en) 2018-04-25 2020-11-27 Childrens Medical Center Abcb5 ligands and substrates
BR112021019349A2 (pt) 2019-03-28 2021-12-07 Childrens Medical Center Células-tronco preparadas altamente funcionais

Also Published As

Publication number Publication date
HK1201295A1 (en) 2015-08-28
ES2511791T3 (es) 2014-10-23
US20180320131A1 (en) 2018-11-08
AU2007254894B2 (en) 2014-10-23
US20230313136A1 (en) 2023-10-05
US8455245B2 (en) 2013-06-04
PT2772535T (pt) 2022-07-04
US11624054B2 (en) 2023-04-11
AU2007254894A1 (en) 2007-12-13
SI2035549T1 (sl) 2015-03-31
HK1129703A1 (en) 2009-12-04
US20130315880A1 (en) 2013-11-28
DK2772535T3 (da) 2022-07-04
EP2035549A1 (en) 2009-03-18
PL2035549T3 (pl) 2014-12-31
LT2772535T (lt) 2022-08-25
US20080003206A1 (en) 2008-01-03
PT2035549E (pt) 2014-10-06
CA2685492A1 (en) 2007-12-13
AU2007254894B9 (en) 2014-11-13
PL2772535T3 (pl) 2022-09-05
DK2035549T3 (da) 2014-10-13
WO2007143139A1 (en) 2007-12-13
CA2685492C (en) 2018-01-16
EP2772535A1 (en) 2014-09-03
US10017738B2 (en) 2018-07-10
ES2918323T3 (es) 2022-07-15
EP2035549B1 (en) 2014-07-09
EP2772535B1 (en) 2022-04-06
SI2772535T1 (sl) 2022-08-31

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