DE69920506T2 - Chemotherapeutische zusammensetzung und verfahren - Google Patents
Chemotherapeutische zusammensetzung und verfahren Download PDFInfo
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- DE69920506T2 DE69920506T2 DE69920506T DE69920506T DE69920506T2 DE 69920506 T2 DE69920506 T2 DE 69920506T2 DE 69920506 T DE69920506 T DE 69920506T DE 69920506 T DE69920506 T DE 69920506T DE 69920506 T2 DE69920506 T2 DE 69920506T2
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- 239000002243 precursor Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000861 pro-apoptotic effect Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- ZDWVWKDAWBGPDN-UHFFFAOYSA-O propidium Chemical compound C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CCC[N+](C)(CC)CC)=C1C1=CC=CC=C1 ZDWVWKDAWBGPDN-UHFFFAOYSA-O 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 229940063675 spermine Drugs 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 229960001603 tamoxifen Drugs 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
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- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000007332 vesicle formation Effects 0.000 description 1
- 229960003048 vinblastine Drugs 0.000 description 1
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11101998P | 1998-12-04 | 1998-12-04 | |
| US111019P | 1998-12-04 | ||
| US12732099P | 1999-04-01 | 1999-04-01 | |
| US127320P | 1999-04-01 | ||
| PCT/CA1999/001157 WO2000033875A1 (en) | 1998-12-04 | 1999-12-03 | Chemotherapeutic composition and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69920506D1 DE69920506D1 (de) | 2004-10-28 |
| DE69920506T2 true DE69920506T2 (de) | 2005-10-13 |
Family
ID=26808584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69920506T Expired - Lifetime DE69920506T2 (de) | 1998-12-04 | 1999-12-03 | Chemotherapeutische zusammensetzung und verfahren |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1135161B1 (https=) |
| JP (1) | JP4380922B2 (https=) |
| AT (1) | ATE276766T1 (https=) |
| AU (1) | AU782335B2 (https=) |
| CA (1) | CA2353905C (https=) |
| DE (1) | DE69920506T2 (https=) |
| DK (1) | DK1135161T3 (https=) |
| ES (1) | ES2229792T3 (https=) |
| NZ (1) | NZ511941A (https=) |
| PT (1) | PT1135161E (https=) |
| WO (1) | WO2000033875A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794368B1 (en) | 1999-04-01 | 2004-09-21 | Bioniche Life Sciences Inc. | Composition and method for inducing apoptosis in prostate cancer cells |
| CA2395493C (en) | 1999-12-28 | 2010-06-22 | Bioniche Life Sciences Inc. | Hyaluronic acid in the treatment of cancer |
| CN105943559A (zh) * | 2010-10-13 | 2016-09-21 | 特莱斯塔治疗知识产权公司 | 细菌核糖核酸细胞壁组合物及其制备和使用方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100533576B1 (ko) * | 1997-08-05 | 2005-12-05 | 바이오니취 라이프 사이언시즈 인코포레이티드 | 세포증식 및 세포사멸 조절용 조성물 및 방법 |
-
1999
- 1999-12-03 CA CA2353905A patent/CA2353905C/en not_active Expired - Fee Related
- 1999-12-03 WO PCT/CA1999/001157 patent/WO2000033875A1/en not_active Ceased
- 1999-12-03 AU AU15412/00A patent/AU782335B2/en not_active Ceased
- 1999-12-03 DE DE69920506T patent/DE69920506T2/de not_active Expired - Lifetime
- 1999-12-03 DK DK99957794T patent/DK1135161T3/da active
- 1999-12-03 ES ES99957794T patent/ES2229792T3/es not_active Expired - Lifetime
- 1999-12-03 AT AT99957794T patent/ATE276766T1/de active
- 1999-12-03 PT PT99957794T patent/PT1135161E/pt unknown
- 1999-12-03 NZ NZ511941A patent/NZ511941A/xx not_active IP Right Cessation
- 1999-12-03 JP JP2000586365A patent/JP4380922B2/ja not_active Expired - Fee Related
- 1999-12-03 EP EP99957794A patent/EP1135161B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU782335B2 (en) | 2005-07-21 |
| WO2000033875A1 (en) | 2000-06-15 |
| ATE276766T1 (de) | 2004-10-15 |
| CA2353905C (en) | 2010-06-22 |
| ES2229792T3 (es) | 2005-04-16 |
| AU1541200A (en) | 2000-06-26 |
| PT1135161E (pt) | 2005-01-31 |
| JP2002531524A (ja) | 2002-09-24 |
| DE69920506D1 (de) | 2004-10-28 |
| EP1135161A1 (en) | 2001-09-26 |
| JP4380922B2 (ja) | 2009-12-09 |
| NZ511941A (en) | 2003-04-29 |
| EP1135161B1 (en) | 2004-09-22 |
| CA2353905A1 (en) | 2000-06-15 |
| DK1135161T3 (da) | 2005-01-24 |
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