DE69914854D1 - Sulfoxidderivate und Acetonkomplexe und Verfahren zu ihrer Herstellung - Google Patents

Sulfoxidderivate und Acetonkomplexe und Verfahren zu ihrer Herstellung

Info

Publication number
DE69914854D1
DE69914854D1 DE69914854T DE69914854T DE69914854D1 DE 69914854 D1 DE69914854 D1 DE 69914854D1 DE 69914854 T DE69914854 T DE 69914854T DE 69914854 T DE69914854 T DE 69914854T DE 69914854 D1 DE69914854 D1 DE 69914854D1
Authority
DE
Germany
Prior art keywords
preparation
sulfoxide derivatives
acetone complexes
complexes
acetone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69914854T
Other languages
English (en)
Other versions
DE69914854T2 (de
Inventor
Masahiko Tsujii
Nobuo Niikawa
Keizo Takayanagi
Shigeharu Nochi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of DE69914854D1 publication Critical patent/DE69914854D1/de
Application granted granted Critical
Publication of DE69914854T2 publication Critical patent/DE69914854T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69914854T 1998-11-16 1999-11-16 Sulfoxidderivate und Acetonkomplexe und Verfahren zu ihrer Herstellung Expired - Lifetime DE69914854T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32566198A JP3926936B2 (ja) 1998-11-16 1998-11-16 スルホキシド誘導体・アセトン錯体およびその製造法
JP32566198 1998-11-16

Publications (2)

Publication Number Publication Date
DE69914854D1 true DE69914854D1 (de) 2004-03-25
DE69914854T2 DE69914854T2 (de) 2005-01-05

Family

ID=18179316

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69914854T Expired - Lifetime DE69914854T2 (de) 1998-11-16 1999-11-16 Sulfoxidderivate und Acetonkomplexe und Verfahren zu ihrer Herstellung

Country Status (7)

Country Link
US (2) US6180652B1 (de)
EP (1) EP1000943B1 (de)
JP (1) JP3926936B2 (de)
KR (1) KR100605270B1 (de)
CN (1) CN1317275C (de)
CA (1) CA2289409C (de)
DE (1) DE69914854T2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3926936B2 (ja) * 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
DE19951960C2 (de) * 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
AU2001296908A1 (en) * 2000-09-29 2002-04-08 Geneva Pharmaceuticals, Inc. Proton pump inhibitor formulation
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
KR100873419B1 (ko) * 2002-06-18 2008-12-11 페어차일드코리아반도체 주식회사 높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
JP2006500380A (ja) * 2002-08-21 2006-01-05 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾールの精製方法
KR20050075424A (ko) * 2002-11-18 2005-07-20 테바 파마슈티컬 인더스트리즈 리미티드 500 ｐｐｍ을 초과하고 약 3,000 ｐｐｍ 이하인 물과 200ｐｐｍ을 초과하고 약 5,000 ｐｐｍ 이하인 알콜을함유하는 안정한 란소프라졸
EP1743893A1 (de) 2002-11-18 2007-01-17 Teva Pharmaceutical Industries Ltd. Stabiles Lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm Wasser und mehr als 200 ppm bis zu 5000 ppm Alkohol
US7507829B2 (en) * 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
JP5031362B2 (ja) * 2003-01-15 2012-09-19 シプラ・リミテッド 製薬的方法、及び該方法により製造された化合物
EP1485373A1 (de) * 2003-02-05 2004-12-15 Teva Pharmaceutical Industries Limited Verfahren zur stabilisierung von lansoprazol
KR100714375B1 (ko) 2003-03-24 2007-05-02 에자이 알앤드디 매니지먼트 가부시키가이샤 술폭시드 유도체 또는 그 염의 아몰퍼스의 제조방법
CA2528993A1 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
ITMI20040802A1 (it) * 2004-04-23 2004-07-23 Dinamite Dipharma S P A In For Polimorfi di pantoprazolo sale sodico e procedimento per la loro preparazione
WO2006003946A1 (ja) * 2004-06-30 2006-01-12 Eisai R & D Management Co., Ltd. ベンズイミダゾール誘導体塩沈殿物の製造方法
CA2575718C (en) 2004-08-06 2010-12-14 Eisai R & D Management Co., Ltd. Salts of benzimidazole derivative with amines and process for manufacturing the same
EP1907375B1 (de) * 2005-06-08 2013-07-24 LEK Pharmaceuticals d.d. Kristallines solvat von omeprazol-natrium
AR058440A1 (es) * 2005-08-02 2008-02-06 Medichem Sa Procesos para la produccion de rabeprazol sodico amorfo
WO2008035189A1 (en) * 2006-09-22 2008-03-27 Orchid Chemicals & Pharmaceuticals Limited A method for the purification of lansoprazole
US20100204478A1 (en) * 2007-05-25 2010-08-12 Hetero Drugs Limited Improved process for amophous rabeprazole sodium
WO2008155780A2 (en) * 2007-06-21 2008-12-24 Matrix Laboratories Ltd Improved process for the preparation of pure rabeprazole
US8071781B2 (en) * 2008-11-11 2011-12-06 Syn-Tech Chem. & Pharm. Co., Ltd. Process for preparing rabeprazole sodium
WO2011004281A1 (en) 2009-07-09 2011-01-13 Alembic Limited A process for the preparation of amorphous form of rabeprazole sodium
ES2391197B1 (es) * 2011-04-27 2013-07-16 Moehs Ibérica S.L. Procedimiento de obtención de rabeprazol sódico amorfo.
WO2014091450A1 (en) 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Process for the preparation of rabeprazole
CN104958276A (zh) * 2015-07-30 2015-10-07 青岛蓝盛洋医药生物科技有限责任公司 一种治疗胃溃疡的药物兰索拉唑组合物胶囊
CN104997738A (zh) * 2015-08-10 2015-10-28 青岛蓝盛洋医药生物科技有限责任公司 一种治疗胃病的药物兰索拉唑组合物干混悬剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794349A (fr) * 1972-01-20 1973-07-23 Glaxo Lab Ltd Nouveau derive de penicilline et son procede de preparation
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
ZA854287B (en) 1984-06-16 1986-02-26 Byk Gulden Lomberg Chem Fab Dialkoxypyridines,process for their preparation,their use and medicaments containing them
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
JPH0674272B2 (ja) 1986-11-13 1994-09-21 エーザイ株式会社 ピリジン誘導体及びそれを含有する潰瘍治療剤
EP1078628B1 (de) * 1994-07-08 2008-11-19 AstraZeneca AB Aus vielen Einzeleinheiten zusammengesetzte tablettierte Dosisform
TW385306B (en) 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
SE510666C2 (sv) 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
JP3926936B2 (ja) * 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法

Also Published As

Publication number Publication date
KR20000035477A (ko) 2000-06-26
EP1000943B1 (de) 2004-02-18
CA2289409C (en) 2008-06-17
US6180652B1 (en) 2001-01-30
CA2289409A1 (en) 2000-05-16
CN1317275C (zh) 2007-05-23
EP1000943A1 (de) 2000-05-17
CN1256275A (zh) 2000-06-14
US6545024B1 (en) 2003-04-08
KR100605270B1 (ko) 2006-07-26
JP3926936B2 (ja) 2007-06-06
JP2000143659A (ja) 2000-05-26
DE69914854T2 (de) 2005-01-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: EISAI R&D MANAGEMENT CO., LTD., TOKYO, JP