DE60039095D1 - Taxolverbindung und Verfahren zu ihrer Herstellung - Google Patents
Taxolverbindung und Verfahren zu ihrer HerstellungInfo
- Publication number
- DE60039095D1 DE60039095D1 DE60039095T DE60039095T DE60039095D1 DE 60039095 D1 DE60039095 D1 DE 60039095D1 DE 60039095 T DE60039095 T DE 60039095T DE 60039095 T DE60039095 T DE 60039095T DE 60039095 D1 DE60039095 D1 DE 60039095D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- taxol compound
- taxol
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26397499A JP4502338B2 (ja) | 1999-09-17 | 1999-09-17 | タキソイド化合物の製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60039095D1 true DE60039095D1 (de) | 2008-07-17 |
Family
ID=17396812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60039095T Expired - Lifetime DE60039095D1 (de) | 1999-09-17 | 2000-03-01 | Taxolverbindung und Verfahren zu ihrer Herstellung |
Country Status (6)
Country | Link |
---|---|
US (1) | US6136990A (de) |
EP (1) | EP1085018B1 (de) |
JP (1) | JP4502338B2 (de) |
AU (1) | AU724835B1 (de) |
CA (1) | CA2299967C (de) |
DE (1) | DE60039095D1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100551945B1 (ko) * | 1997-12-19 | 2006-02-20 | 가부시키가이샤 야쿠루트 혼샤 | 택산 유도체 |
US6410757B1 (en) | 1999-02-16 | 2002-06-25 | Bio Research Corporation Of Yokohama | Baccatin derivatives and a process for producing the same |
WO2000073293A1 (en) * | 1999-05-28 | 2000-12-07 | Bristol-Myers Squibb Co. | Semi-synthesis of paclitaxel using dialkyldichlorosilanes |
US6479679B1 (en) * | 2001-04-25 | 2002-11-12 | Napro Biotherapeutics, Inc. | Two-step conversion of protected taxane ester to paclitaxel |
CA2696856A1 (en) * | 2007-08-22 | 2009-02-26 | 6570763 Canada Inc. | Process for converting 9-dihydro-13-acetylbaccatin iii into docetaxel or paclitaxel |
WO2017006573A1 (ja) * | 2015-07-07 | 2017-01-12 | 忠勝 萬代 | パクリタキセル及びドセタキセルの側鎖前駆体の製造方法 |
CN114573631B (zh) * | 2022-03-10 | 2024-06-18 | 清远中大创新药物研究中心 | 一种利用三组分反应一步合成紫杉醇侧链及其类似物的方法及其应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
US5710287A (en) * | 1991-09-23 | 1998-01-20 | Florida State University | Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them |
FR2696464B1 (fr) * | 1992-10-05 | 1994-11-10 | Rhone Poulenc Rorer Sa | Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III. |
FR2697522B1 (fr) * | 1992-10-30 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
US6040466A (en) * | 1996-03-25 | 2000-03-21 | Rhone Poulenc Rorer Sa | Taxoids, their preparation and pharmaceutical compositions containing them |
US5948919A (en) * | 1993-02-05 | 1999-09-07 | Napro Biotherapeutics, Inc. | Paclitaxel synthesis from precursor compounds and methods of producing the same |
DE69432140T2 (de) * | 1993-03-05 | 2003-07-31 | Florida State University, Tallahassee | Verfahren zur Herstellung von 9-Desoxotaxanen |
US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
US5786489A (en) * | 1994-02-08 | 1998-07-28 | The Scripps Research Institute | Transformations of taxol |
EP0738265A1 (de) * | 1994-11-04 | 1996-10-23 | PHARMACIA S.p.A. | Taxan derivate |
US5773461A (en) * | 1996-06-06 | 1998-06-30 | Bristol-Myers Squibb Company | 7-deoxy-6-substituted paclitaxels |
JPH11116562A (ja) * | 1997-10-13 | 1999-04-27 | Tanabe Seiyaku Co Ltd | バッカチン誘導体の製法 |
US5917062A (en) * | 1997-11-21 | 1999-06-29 | Indena S.P.A | Intermediates and methods useful in the semisynthesis of paclitaxel and analogs |
US6066748A (en) * | 1997-12-17 | 2000-05-23 | Han; Man Woo | Process of extracting TAXOL® from taxus cuspidata |
US6066749A (en) * | 1998-05-01 | 2000-05-23 | Napro Biotherapeutics, Inc. | Method for conversion of C-2'-O-protected-10-hydroxy taxol to c-2'-O-protected taxol:useful intermediates in paclitaxel synthesis |
US6410757B1 (en) * | 1999-02-16 | 2002-06-25 | Bio Research Corporation Of Yokohama | Baccatin derivatives and a process for producing the same |
-
1999
- 1999-09-17 JP JP26397499A patent/JP4502338B2/ja not_active Expired - Fee Related
-
2000
- 2000-02-15 US US09/504,788 patent/US6136990A/en not_active Expired - Lifetime
- 2000-02-17 AU AU17557/00A patent/AU724835B1/en not_active Ceased
- 2000-02-29 CA CA002299967A patent/CA2299967C/en not_active Expired - Fee Related
- 2000-03-01 DE DE60039095T patent/DE60039095D1/de not_active Expired - Lifetime
- 2000-03-01 EP EP00103473A patent/EP1085018B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2299967A1 (en) | 2001-03-17 |
JP4502338B2 (ja) | 2010-07-14 |
JP2001089464A (ja) | 2001-04-03 |
AU724835B1 (en) | 2000-09-28 |
CA2299967C (en) | 2005-04-19 |
US6136990A (en) | 2000-10-24 |
EP1085018B1 (de) | 2008-06-04 |
EP1085018A1 (de) | 2001-03-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |