DE69906147T2 - Zerkleinerungsverfahren zur herstellung von feingemahlenen medizinischen substanzen - Google Patents

Zerkleinerungsverfahren zur herstellung von feingemahlenen medizinischen substanzen

Info

Publication number
DE69906147T2
DE69906147T2 DE69906147T DE69906147T DE69906147T2 DE 69906147 T2 DE69906147 T2 DE 69906147T2 DE 69906147 T DE69906147 T DE 69906147T DE 69906147 T DE69906147 T DE 69906147T DE 69906147 T2 DE69906147 T2 DE 69906147T2
Authority
DE
Germany
Prior art keywords
milling
production
elements
decomposition process
medical substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69906147T
Other languages
English (en)
Other versions
DE69906147D1 (de
Inventor
Jean-Rene Authelin
Patrick Hosek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Aventis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Ltd filed Critical Aventis Pharma Ltd
Publication of DE69906147D1 publication Critical patent/DE69906147D1/de
Application granted granted Critical
Publication of DE69906147T2 publication Critical patent/DE69906147T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00—Other disintegrating devices or methods
    • B02C19/06—Jet mills
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00—Other disintegrating devices or methods
    • B02C19/18—Use of auxiliary physical effects, e.g. ultrasonics, irradiation, for disintegrating
    • B02C19/186—Use of cold or heat for disintegrating

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Disintegrating Or Milling (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Crushing And Grinding (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Finish Polishing, Edge Sharpening, And Grinding By Specific Grinding Devices (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69906147T 1998-12-01 1999-12-01 Zerkleinerungsverfahren zur herstellung von feingemahlenen medizinischen substanzen Expired - Lifetime DE69906147T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9826286.8A GB9826286D0 (en) 1998-12-01 1998-12-01 Process
PCT/GB1999/004047 WO2000032313A1 (en) 1998-12-01 1999-12-01 Milling process for the production of finely milled medicinal substances

Publications (2)

Publication Number Publication Date
DE69906147D1 DE69906147D1 (de) 2003-04-24
DE69906147T2 true DE69906147T2 (de) 2003-12-04

Family

ID=10843362

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69906147T Expired - Lifetime DE69906147T2 (de) 1998-12-01 1999-12-01 Zerkleinerungsverfahren zur herstellung von feingemahlenen medizinischen substanzen

Country Status (25)

Country Link
US (2) US7041318B2 (de)
EP (2) EP1338273B1 (de)
JP (1) JP4592955B2 (de)
KR (1) KR100658010B1 (de)
CN (1) CN1096886C (de)
AT (1) ATE234684T1 (de)
AU (1) AU758212B2 (de)
BR (1) BRPI9915841B8 (de)
CA (1) CA2352779A1 (de)
CZ (2) CZ296782B6 (de)
DE (1) DE69906147T2 (de)
DK (2) DK1338273T3 (de)
ES (2) ES2634255T3 (de)
GB (1) GB9826286D0 (de)
HK (1) HK1037563A1 (de)
HU (1) HU226221B1 (de)
IL (1) IL143345A (de)
MX (1) MXPA01005471A (de)
NO (1) NO324231B1 (de)
NZ (1) NZ512091A (de)
PL (1) PL193799B1 (de)
PT (1) PT1146964E (de)
RU (1) RU2234375C2 (de)
SI (1) SI1146964T1 (de)
WO (1) WO2000032313A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011102614A1 (de) * 2011-05-27 2012-11-29 Roland Nied Verfahren zum Betrieb einer Strahlmühle sowie Strahlmühle

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
JO3510B1 (ar) * 2011-03-04 2020-07-05 Heptares Therapeutics Ltd استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
EA037332B1 (ru) 2014-09-09 2021-03-15 Вектура Лимитед Композиция, содержащая гликопирролат, способ и устройство
RU2623608C1 (ru) * 2016-02-09 2017-06-28 Владимир Никитович Анциферов Способ размола порошка из пластичного материала
CN109097582B (zh) * 2018-08-17 2020-07-03 安阳工学院 一种机械工程粉状废弃物处理系统
JP7090941B2 (ja) * 2018-10-02 2022-06-27 学校法人 名城大学 吸入粉末剤、その評価方法及びその用途
CN113751171A (zh) * 2021-09-14 2021-12-07 威海德尚医中医药科技有限公司 一种中药超微细粉制剂的制备方法
CN115737610B (zh) * 2021-12-13 2024-02-27 苏州欧米尼医药有限公司 一种噻托溴铵吸入粉雾剂及其活性成分的气流粉碎方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3897010A (en) * 1971-07-02 1975-07-29 Linde Ag Method of and apparatus for the milling of granular materials
DE2133019A1 (de) * 1971-07-02 1973-01-18 Linde Ag Verfahren und vorrichtung zum kaltstrahlmahlen
GB1481304A (en) * 1974-09-05 1977-07-27 Boc International Ltd Powder forming
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
US4767612A (en) * 1987-01-23 1988-08-30 Rorer Pharmaceutical Corporation Triamcinolone acetonide for the treatment of allergic rhinitis
FR2628415A1 (fr) * 1988-03-09 1989-09-15 Rhone Poulenc Chimie Procede de fabrication de materiaux supraconducteurs et produits ainsi obtenus
EP0407028B2 (de) 1989-05-31 1999-07-07 FISONS plc Medikament und Inhalationsvorrichtung dafür
SE9101090D0 (sv) 1991-04-11 1991-04-11 Astra Ab Process for conditioning of water-soluble substances
SE9302777D0 (sv) 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5747002A (en) * 1995-04-05 1998-05-05 Genentech, Inc. Preparation of sodium chloride aerosol formulations
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US5682658A (en) 1996-03-04 1997-11-04 Utica Enterprises, Inc. Rotary index table assembly
AU717013B2 (en) * 1996-03-08 2000-03-16 E.I. Du Pont De Nemours And Company Improved fluid energy mill
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011102614A1 (de) * 2011-05-27 2012-11-29 Roland Nied Verfahren zum Betrieb einer Strahlmühle sowie Strahlmühle
US9010666B2 (en) 2011-05-27 2015-04-21 Netzsch Trockenmahltechnik Gmbh Jet mill and method for operation of a jet mill

Also Published As

Publication number Publication date
DE69906147D1 (de) 2003-04-24
WO2000032313A1 (en) 2000-06-08
JP2002531240A (ja) 2002-09-24
ES2195668T3 (es) 2003-12-01
CN1096886C (zh) 2002-12-25
MXPA01005471A (es) 2003-03-27
DK1146964T3 (da) 2003-06-02
PT1146964E (pt) 2003-08-29
NO20012653D0 (no) 2001-05-30
US7041318B2 (en) 2006-05-09
BRPI9915841B1 (pt) 2016-11-22
HK1037563A1 (en) 2002-02-15
KR20010093130A (ko) 2001-10-27
NO324231B1 (no) 2007-09-10
JP4592955B2 (ja) 2010-12-08
GB9826286D0 (en) 1999-01-20
CA2352779A1 (en) 2000-06-08
EP1338273A2 (de) 2003-08-27
AU758212B2 (en) 2003-03-20
HU226221B1 (en) 2008-06-30
PL348613A1 (en) 2002-06-03
EP1146964B1 (de) 2003-03-19
CZ20011874A3 (cs) 2001-12-12
EP1146964A1 (de) 2001-10-24
RU2234375C2 (ru) 2004-08-20
EP1338273A3 (de) 2003-11-05
CZ296782B6 (cs) 2006-06-14
SI1146964T1 (en) 2003-10-31
CZ307438B6 (cs) 2018-08-22
PL193799B1 (pl) 2007-03-30
BR9915841A (pt) 2001-09-04
BRPI9915841B8 (pt) 2021-05-25
US20020114766A1 (en) 2002-08-22
EP1338273B1 (de) 2017-06-07
CN1328489A (zh) 2001-12-26
US20060002864A1 (en) 2006-01-05
NO20012653L (no) 2001-05-30
HUP0201662A2 (en) 2002-09-28
AU1401200A (en) 2000-06-19
NZ512091A (en) 2003-03-28
ATE234684T1 (de) 2003-04-15
ES2634255T3 (es) 2017-09-27
DK1338273T3 (en) 2017-09-18
IL143345A (en) 2005-11-20
KR100658010B1 (ko) 2006-12-15
IL143345A0 (en) 2002-04-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC