DE69832283D1 - Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität - Google Patents

Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität

Info

Publication number
DE69832283D1
DE69832283D1 DE69832283T DE69832283T DE69832283D1 DE 69832283 D1 DE69832283 D1 DE 69832283D1 DE 69832283 T DE69832283 T DE 69832283T DE 69832283 T DE69832283 T DE 69832283T DE 69832283 D1 DE69832283 D1 DE 69832283D1
Authority
DE
Germany
Prior art keywords
thioesterases
plant
thioesterase
plants
engineered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832283T
Other languages
English (en)
Other versions
DE69832283T2 (de
Inventor
Ling Yuan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Calgene LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calgene LLC filed Critical Calgene LLC
Application granted granted Critical
Publication of DE69832283D1 publication Critical patent/DE69832283D1/de
Publication of DE69832283T2 publication Critical patent/DE69832283T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69832283T 1997-06-03 1998-06-03 Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität Expired - Lifetime DE69832283T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US868458 1997-06-03
US08/868,458 US6150512A (en) 1995-05-15 1997-06-03 Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity
PCT/US1998/011697 WO1998055633A1 (en) 1997-06-03 1998-06-03 Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity

Publications (2)

Publication Number Publication Date
DE69832283D1 true DE69832283D1 (de) 2005-12-15
DE69832283T2 DE69832283T2 (de) 2006-08-10

Family

ID=25351727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832283T Expired - Lifetime DE69832283T2 (de) 1997-06-03 1998-06-03 Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität

Country Status (9)

Country Link
US (1) US6150512A (de)
EP (2) EP1003884B1 (de)
JP (1) JP2002502263A (de)
AT (1) ATE309372T1 (de)
BR (1) BR9810402A (de)
CA (1) CA2291452A1 (de)
DE (1) DE69832283T2 (de)
ES (1) ES2251770T3 (de)
WO (1) WO1998055633A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2382693C (en) * 1999-08-26 2013-10-01 Calgene Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7531718B2 (en) * 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7166771B2 (en) * 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
US7566813B2 (en) * 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
AR039113A1 (es) * 2002-03-21 2005-02-09 Monsanto Technology Llc Construcciones de acidos nucleicos y metodos para producir composiciones de aceites de semillas alteradas
AR039717A1 (es) * 2002-06-21 2005-03-09 Monsanto Technology Llc Construcciones de arn de intrones cadena doble y usos de las mismas
JP4840360B2 (ja) * 2005-06-30 2011-12-21 トヨタ自動車株式会社 ペトロセリン酸生合成に関与する新規遺伝子、ペトロセリン酸の製造方法
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
RU2483057C2 (ru) 2006-06-28 2013-05-27 Ньюселис Инк. Смеси жирных кислот и их применение
CA2662607A1 (en) * 2006-09-08 2008-03-13 Kaneka Corporation Composition comprising reduced coenzyme q10 and lysolecithin
MX2010006539A (es) * 2007-12-11 2011-02-23 Synthetic Genomics Inc Secrecion de acidos grasos por parte de microorganismos fotosinteticos.
CA2710767C (en) * 2007-12-27 2016-09-27 Cibus Llc Alkylester fatty acid blends and uses therefor
WO2010021711A1 (en) * 2008-08-18 2010-02-25 Ls9, Inc. Systems and methods for the production of mixed fatty esters
JP5767585B2 (ja) 2008-09-29 2015-08-19 モンサント テクノロジー エルエルシー 大豆遺伝子組換え事象ｍｏｎ８７７０５およびその検出方法
EP2448955B1 (de) 2009-06-29 2015-09-30 Synthetic Genomics, Inc. Acyl-acp-thioesterasegene und verwendungen dafür
CA2782423C (en) * 2009-12-18 2019-06-18 Cargill Incorporated Brassica plants yielding oils with a low total saturated fatty acid content
EP2576765A4 (de) 2010-05-25 2013-12-18 Cargill Inc Kohlpflanzen zur gewinnung von ölen mit geringem anteil an alpha-linolensäure
US9695434B2 (en) 2010-05-25 2017-07-04 Cargill, Incorporated Brassica plants yielding oils with a low alpha linolenic acid content
US9399768B2 (en) 2011-07-27 2016-07-26 Iowa State University Research Foundation, Inc. Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis
US8951762B2 (en) 2011-07-27 2015-02-10 Iowa State University Research Foundation, Inc. Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis
WO2013096082A1 (en) 2011-12-20 2013-06-27 Codexis, Inc. Fatty alcohol forming acyl reductase (far) variants and methods of use
WO2013159055A1 (en) 2012-04-20 2013-10-24 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
JP6006553B2 (ja) * 2012-07-10 2016-10-12 花王株式会社 組換えクラミドモナス属及びそれを用いたラウリン酸高含有油脂の製造方法
WO2014015278A1 (en) 2012-07-20 2014-01-23 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
JP5925651B2 (ja) * 2012-09-20 2016-05-25 花王株式会社 チオエステラーゼ改変体を用いた脂質の製造方法
CA2888197C (en) 2012-10-15 2023-03-07 Genomatica, Inc. Microorganisms and methods for production of specific length fatty alcohols and related compounds
US9512447B2 (en) 2012-12-14 2016-12-06 Codexis, Inc. Modified native beta-ketoacyl-ACP synthases and engineered microorganisms
JP6491881B2 (ja) 2012-12-27 2019-03-27 花王株式会社 アシル−ａｃｐチオエステラーゼ
US9567615B2 (en) * 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2971021A4 (de) 2013-03-15 2016-12-21 Genomatica Inc Mikroorganismen und verfahren zur herstellung von butadien und verwandten verbindungen mittels formatassimilation
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US11814664B2 (en) 2013-05-24 2023-11-14 Genomatica, Inc. Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate
WO2015005139A1 (ja) 2013-07-12 2015-01-15 花王株式会社 アシル－ａｃｐチオエステラーゼ
WO2015077752A1 (en) 2013-11-25 2015-05-28 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
AU2015277857B2 (en) 2014-06-20 2021-07-22 Kao Corporation Method for producing lipid
EP3172320B1 (de) * 2014-07-24 2019-11-20 Corbion Biotech, Inc. Variante thioesterasen und verfahren zur verwendung
BR112017005370A2 (pt) 2014-09-18 2017-12-12 Terravia Holdings Inc acil-acp tioesterases e mutantes das mesmas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753475A (en) 1985-01-17 1998-05-19 Calgene, Inc. Methods and compositions for regulated transcription and expression of heterologous genes
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
EP0563191B2 (de) 1990-12-20 2000-01-19 E.I. Du Pont De Nemours And Company Nukleotidsequenzen der sojabohnen-acyl-acp-thioesterasegene
US5455167A (en) 1991-05-21 1995-10-03 Calgene Inc. Medium-chain thioesterases in plants
US5850022A (en) * 1992-10-30 1998-12-15 Calgene, Inc. Production of myristate in plant cells
EP0728212A1 (de) * 1993-11-10 1996-08-28 Calgene, Inc. Pflanzen acyl-acp thioesterase sequenzen
US5910630A (en) 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
CA2206984A1 (en) * 1995-05-15 1996-11-21 Calgene, Inc. Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity
CA2205657A1 (en) * 1995-09-29 1997-04-03 Calgene, Inc. Plant stearoyl-acp thioesterase sequences and methods to increase stearate content in plant seed oils

Also Published As

Publication number Publication date
DE69832283T2 (de) 2006-08-10
JP2002502263A (ja) 2002-01-22
CA2291452A1 (en) 1998-12-10
US6150512A (en) 2000-11-21
ATE309372T1 (de) 2005-11-15
BR9810402A (pt) 2000-08-29
EP1003884A1 (de) 2000-05-31
EP1003884B1 (de) 2005-11-09
WO1998055633A1 (en) 1998-12-10
EP1605048A1 (de) 2005-12-14
ES2251770T3 (es) 2006-05-01

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