DE69825789T2 - Vorrichtung und verfahren zur stoss-induzierten dissoziation von ionen in einem quadrupol-ionenleiter - Google Patents

Vorrichtung und verfahren zur stoss-induzierten dissoziation von ionen in einem quadrupol-ionenleiter Download PDF

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Publication number
DE69825789T2
DE69825789T2 DE69825789T DE69825789T DE69825789T2 DE 69825789 T2 DE69825789 T2 DE 69825789T2 DE 69825789 T DE69825789 T DE 69825789T DE 69825789 T DE69825789 T DE 69825789T DE 69825789 T2 DE69825789 T2 DE 69825789T2
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DE
Germany
Prior art keywords
quadrupole
ions
ion
ion guide
section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69825789T
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German (de)
English (en)
Other versions
DE69825789D1 (de
Inventor
Alexandre V. Loboda
Andrei Krouttchinskikh
Victor Spicer
Werner Ens
Kenneth Standing
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University of Manitoba
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University of Manitoba
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Publication date
Application filed by University of Manitoba filed Critical University of Manitoba
Publication of DE69825789D1 publication Critical patent/DE69825789D1/de
Application granted granted Critical
Publication of DE69825789T2 publication Critical patent/DE69825789T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0063—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by applying a resonant excitation voltage
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
DE69825789T 1997-12-04 1998-11-27 Vorrichtung und verfahren zur stoss-induzierten dissoziation von ionen in einem quadrupol-ionenleiter Expired - Lifetime DE69825789T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6704597P 1997-12-04 1997-12-04
US67045P 1997-12-04
PCT/CA1998/001098 WO1999030351A1 (en) 1997-12-04 1998-11-27 Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide

Publications (2)

Publication Number Publication Date
DE69825789D1 DE69825789D1 (de) 2004-09-23
DE69825789T2 true DE69825789T2 (de) 2005-09-01

Family

ID=22073366

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825789T Expired - Lifetime DE69825789T2 (de) 1997-12-04 1998-11-27 Vorrichtung und verfahren zur stoss-induzierten dissoziation von ionen in einem quadrupol-ionenleiter

Country Status (8)

Country Link
US (1) US6512226B1 (enExample)
EP (1) EP1051733B1 (enExample)
JP (1) JP4463978B2 (enExample)
AT (1) ATE274235T1 (enExample)
AU (1) AU1329099A (enExample)
CA (1) CA2312754C (enExample)
DE (1) DE69825789T2 (enExample)
WO (1) WO1999030351A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9820210D0 (en) * 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
US6124591A (en) * 1998-10-16 2000-09-26 Finnigan Corporation Method of ion fragmentation in a quadrupole ion trap
US6806463B2 (en) * 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US7157700B2 (en) * 2001-06-30 2007-01-02 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
JP2003507874A (ja) * 1999-08-26 2003-02-25 ユニバーシティ オブ ニュー ハンプシャー 多段型の質量分析計
US6822224B2 (en) * 2000-03-14 2004-11-23 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (FAIMS)tandem mass spectrometry
US7041967B2 (en) * 2001-05-25 2006-05-09 Mds Inc. Method of mass spectrometry, to enhance separation of ions with different charges
US7119328B2 (en) * 2001-06-30 2006-10-10 Sionex Corporation System for DMS peak resolution
US6946653B2 (en) 2001-11-27 2005-09-20 Ciphergen Biosystems, Inc. Methods and apparatus for improved laser desorption ionization tandem mass spectrometry
US7122794B1 (en) * 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
GB0210930D0 (en) * 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
US6982417B2 (en) * 2003-10-09 2006-01-03 Siemens Energy & Automation, Inc. Method and apparatus for detecting low-mass ions
WO2005067582A2 (en) * 2004-01-13 2005-07-28 Sionex Corporation Methods and apparatus for enhanced sample identification based on combined analytical techniques
CA2604820A1 (en) 2004-02-23 2005-09-09 Gemio Technologies, Inc. Ion source with controlled superposition of electrostatic and gas flow fields
US8003934B2 (en) 2004-02-23 2011-08-23 Andreas Hieke Methods and apparatus for ion sources, ion control and ion measurement for macromolecules
GB0420408D0 (en) * 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
GB0425426D0 (en) * 2004-11-18 2004-12-22 Micromass Ltd Mass spectrometer
GB0427632D0 (en) * 2004-12-17 2005-01-19 Micromass Ltd Mass spectrometer
EP1913379A2 (en) 2005-07-26 2008-04-23 Sionex Corporation Ultra compact ion mobility based analyzer apparatus, method, and system
US7737396B2 (en) * 2008-01-30 2010-06-15 Mds Analytical Technologies, A Business Unit Of Mds Inc. Ion fragmentation in mass spectrometry
CN105051530B (zh) 2013-03-14 2018-05-01 莱克公司 用于串联质谱分析的系统和方法
US8772711B1 (en) 2013-08-27 2014-07-08 Battelle Memorial Institute Apparatus and method of dissociating ions in a multipole ion guide
CN108376637B (zh) * 2018-04-19 2023-05-26 南京信息工程大学 实现对自由飞行区解离碎片分辨的离子速度成像仪
CN110729171B (zh) * 2018-07-17 2022-05-17 株式会社岛津制作所 四极质量分析器及质量分析方法
US20240234123A1 (en) * 2020-11-19 2024-07-11 Dh Technologies Development Pte. Ltd. Method of Performing MS/MS of High Intensity Ion Beams Using a Bandpass Filtering Collision Cell to Enhance Mass Spectrometry Robustness

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234791A (en) 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US5089703A (en) 1991-05-16 1992-02-18 Finnigan Corporation Method and apparatus for mass analysis in a multipole mass spectrometer
US5179278A (en) 1991-08-23 1993-01-12 Mds Health Group Limited Multipole inlet system for ion traps
US5448061A (en) * 1992-05-29 1995-09-05 Varian Associates, Inc. Method of space charge control for improved ion isolation in an ion trap mass spectrometer by dynamically adaptive sampling
DE4316737C1 (de) * 1993-05-19 1994-09-01 Bruker Franzen Analytik Gmbh Verfahren zur digitalen Erzeugung einer zusätzlichen Wechselspannung für die resonante Anregung von Ionen in Ionenfallen
DE69535979D1 (de) * 1994-02-28 2009-08-20 Analytica Of Branford Inc Multipol-ionenleiter für massenspektrometrie
US6011259A (en) * 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
US5420425A (en) * 1994-05-27 1995-05-30 Finnigan Corporation Ion trap mass spectrometer system and method
DE19520319A1 (de) * 1995-06-02 1996-12-12 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für die Einführung von Ionen in Quadrupol-Ionenfallen
US5576540A (en) * 1995-08-11 1996-11-19 Mds Health Group Limited Mass spectrometer with radial ejection
US5672870A (en) 1995-12-18 1997-09-30 Hewlett Packard Company Mass selective notch filter with quadrupole excision fields

Also Published As

Publication number Publication date
WO1999030351A1 (en) 1999-06-17
US6512226B1 (en) 2003-01-28
JP4463978B2 (ja) 2010-05-19
EP1051733B1 (en) 2004-08-18
DE69825789D1 (de) 2004-09-23
CA2312754C (en) 2007-10-09
ATE274235T1 (de) 2004-09-15
JP2001526448A (ja) 2001-12-18
AU1329099A (en) 1999-06-28
EP1051733A1 (en) 2000-11-15
CA2312754A1 (en) 1999-06-17

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