DE69809282D1 - Verfahren zur gewinnung von enantiomeren von cis-olirtin - Google Patents

Verfahren zur gewinnung von enantiomeren von cis-olirtin

Info

Publication number
DE69809282D1
DE69809282D1 DE69809282T DE69809282T DE69809282D1 DE 69809282 D1 DE69809282 D1 DE 69809282D1 DE 69809282 T DE69809282 T DE 69809282T DE 69809282 T DE69809282 T DE 69809282T DE 69809282 D1 DE69809282 D1 DE 69809282D1
Authority
DE
Germany
Prior art keywords
cis
olirtin
enantiomer
order
obtaining enantiomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69809282T
Other languages
English (en)
Other versions
DE69809282T2 (de
Inventor
Antoni Torrens-Jover
Jordi Frigola-Constansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of DE69809282D1 publication Critical patent/DE69809282D1/de
Application granted granted Critical
Publication of DE69809282T2 publication Critical patent/DE69809282T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69809282T 1997-08-04 1998-07-31 Verfahren zur gewinnung von enantiomeren von cis-olirtin Expired - Fee Related DE69809282T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701728A ES2130083B1 (es) 1997-08-04 1997-08-04 Procedimiento para la obtencion de los enantiomeros de cizolirtina.
PCT/ES1998/000223 WO1999007684A1 (es) 1997-08-04 1998-07-31 Procedimiento para la obtencion de los enantiomeros de cizolirtina

Publications (2)

Publication Number Publication Date
DE69809282D1 true DE69809282D1 (de) 2002-12-12
DE69809282T2 DE69809282T2 (de) 2003-09-11

Family

ID=8300306

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69809282T Expired - Fee Related DE69809282T2 (de) 1997-08-04 1998-07-31 Verfahren zur gewinnung von enantiomeren von cis-olirtin

Country Status (12)

Country Link
US (1) US6118009A (de)
EP (1) EP1029852B1 (de)
JP (1) JP2001512718A (de)
AT (1) ATE227272T1 (de)
AU (1) AU8442698A (de)
CA (1) CA2299447C (de)
DE (1) DE69809282T2 (de)
DK (1) DK1029852T3 (de)
ES (2) ES2130083B1 (de)
NO (1) NO314499B1 (de)
PT (1) PT1029852E (de)
WO (1) WO1999007684A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142929A1 (en) * 2001-07-06 2004-07-22 Ramon Merce-Vidal Derivatives of aryl (or heteroaryl) azolylcarbinoles for the treatment of urinary incontinence
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
EP1584335A3 (de) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Zusammensetzung aus Aktiva mit einer Carbinolverbindung und einem Opioid
CA2562231A1 (en) * 2004-04-05 2005-10-20 Laboratorios Del Dr. Esteve, S.A. Active substance combination of a carbinol compound and an opioid
ES2244326B1 (es) * 2004-04-05 2007-02-16 Laboratorios Del Dr. Esteve, S.A. Combinacion de substancias activas.
US20060040924A1 (en) * 2004-06-22 2006-02-23 Laboratorios Dr. Esteve S.A. Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic
EP1671953A1 (de) * 2004-12-17 2006-06-21 Laboratorios Del Dr. Esteve, S.A. Verfahren zur Herstellung von Cizolirtine und dessen Enantiomeren
WO2006063861A1 (en) * 2004-12-17 2006-06-22 Laboratorios Del Dr. Esteve, S.A. Process for obtaining cizolirtine and its enantiomers
EP1671968A1 (de) * 2004-12-17 2006-06-21 Laboratorios Del Dr. Esteve, S.A. Verfahren zur Herstellung von Enantiomeren von Thienylazolylalkoxyethanamines
US7897589B2 (en) * 2005-07-15 2011-03-01 Laboratorios Del Dr. Esteve, S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
EP1757587A1 (de) * 2005-07-15 2007-02-28 Laboratorios Del Dr. Esteve, S.A. Substituierte Pyrazolinderivate, ihre Herstellung und Verwendung als Arzneimittel
EP1743890A1 (de) 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. 4,5-Dihydro-1H-Pyrazol-Derivative, Verfahren zur Herstellung und ihre Verwendung als Medikamente.
EP1743892A1 (de) * 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Substituierte Pyrazolin Verbindungen, deren Herstellung und Verwendung als Medikament
EP1820502A1 (de) 2006-02-10 2007-08-22 Laboratorios Del Dr. Esteve, S.A. Wirkstoffzusammensetzungen enthaltend Azolycarbinolderivate
EP2151234A1 (de) * 2008-07-28 2010-02-10 Laboratorios Del. Dr. Esteve, S.A. Pharmazeutische Formulierung mit einer CB1-Rezeptorverbindung in einer festen Lösung und/oder festen Dispersion
WO2010123999A2 (en) * 2009-04-21 2010-10-28 Auspex Pharmaceuticals, Inc. 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor
DE102010056283A1 (de) 2010-12-24 2012-06-28 Volkswagen Ag Wärmeübertragungssystem
CN108558695A (zh) * 2018-05-15 2018-09-21 浙江华贝药业有限责任公司 2，2，2-三氟-n-[(1s，4s)-4-羟基四氢萘-1-基]-乙酰胺制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
KR950701637A (ko) * 1992-05-14 1995-04-28 알렌 제이. 스피겔 에난티오 선택적인 옥사자보롤리딘 촉매(enantioselective oxazaborolidine catalysts)
US5442118A (en) * 1994-04-22 1995-08-15 Sepracor, Inc. Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones

Also Published As

Publication number Publication date
CA2299447A1 (en) 1999-02-18
NO20000560D0 (no) 2000-02-03
DK1029852T3 (da) 2003-02-24
EP1029852A1 (de) 2000-08-23
ES2130083B1 (es) 2000-01-16
AU8442698A (en) 1999-03-01
ATE227272T1 (de) 2002-11-15
PT1029852E (pt) 2003-03-31
ES2187044T3 (es) 2003-05-16
CA2299447C (en) 2007-05-29
WO1999007684A1 (es) 1999-02-18
DE69809282T2 (de) 2003-09-11
EP1029852B1 (de) 2002-11-06
ES2130083A1 (es) 1999-06-16
JP2001512718A (ja) 2001-08-28
NO20000560L (no) 2000-03-29
NO314499B1 (no) 2003-03-31
US6118009A (en) 2000-09-12

Similar Documents

Publication Publication Date Title
DE69809282D1 (de) Verfahren zur gewinnung von enantiomeren von cis-olirtin
DE59705550D1 (de) Verfahren zur herstellung von nitrobiphenylen
ATE273945T1 (de) Verfahren zur kristallisierung von sterisch gehinderten verbindungen
DE69805926T2 (de) Verfahren zur Herstellung von Sevoflurane
DE69517832T2 (de) Ein Verfahren zur Herstellung von Tetrazolyl-Verbindungen
ATE417913T1 (de) Kontinuierliches verfahren zur entfernung von kontaminationen aus altöl
ATE264826T1 (de) Verfahren zur trennung einer enantiomermischung
ATE366264T1 (de) Verfahren zur herstellung von vernetzten polyallyaminderivaten
DE59811659D1 (de) Verfahren zur Herstellung eines Metallocen-Katalysatorsystems
ATE281879T1 (de) Verfahren zur abtrennung organischer substanzen aus einem wässrigen gemisch
KR960702468A (ko) 거울상선택적 옥사자보로리딘 촉매(Enantioselective oxazaborolidine catalysts)
DE3871608D1 (de) Verfahren zur herstellung von mehrkernigen aromatischen polyaminen.
BR0111317A (pt) Processo para preparar compostos, composto, sistema de catalisador, e, usos de um composto e de um sistema de catalisador
ATE231492T1 (de) Verfahren zur herstellung von pyrrolamiden
DE60115444D1 (de) Verfahren zur herstellung von biphenyl-verbindungen
DE50211314D1 (de) Verfahren zur katalytischen Hydrierung
ATE80619T1 (de) Verfahren zur herstellung von unsymmetrischen dihydropyridinen.
ATE253579T1 (de) Verfahren zur herstellung eines enantiomers von narwedin
ATE204842T1 (de) Verfahren zur herstellung von calixarenen
ATE301637T1 (de) Verfahren zur herstellung von n-geschützten azetidin-2-carbonsäuren
ATE255101T1 (de) Verfahren zur herstellung von aromatischen verbindungen die ein heterozyklisches system enthalten
DE69812858D1 (de) Verfahren zur Herstellung von (R)-3-Hydroxy-4-Butyrolacton, nützlich für die Herstellung von (R)-Carnitin
ATE193520T1 (de) Verfahren zur herstellung von aminoalkynen
SE9801726D0 (sv) New process
YU49461B (sh) Postupak za dobijanje glicidil estara zasićenih karbonskih kiselina

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee