DE69802587T2 - Integrierte mikrokeramische chemische Anlage - Google Patents

Integrierte mikrokeramische chemische Anlage

Info

Publication number
DE69802587T2
DE69802587T2 DE69802587T DE69802587T DE69802587T2 DE 69802587 T2 DE69802587 T2 DE 69802587T2 DE 69802587 T DE69802587 T DE 69802587T DE 69802587 T DE69802587 T DE 69802587T DE 69802587 T2 DE69802587 T2 DE 69802587T2
Authority
DE
Germany
Prior art keywords
chemical plant
integrated micro
ceramic chemical
ceramic
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69802587T
Other languages
English (en)
Other versions
DE69802587D1 (de
Inventor
Syamal K Ghosh
Dilip K Chatterjee
Edward P Furlani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastman Kodak Co
Original Assignee
Eastman Kodak Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co
Application granted granted Critical
Publication of DE69802587D1 publication Critical patent/DE69802587D1/de
Publication of DE69802587T2 publication Critical patent/DE69802587T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/422—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path between stacked plates, e.g. grooved or perforated plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/051—Stirrers characterised by their elements, materials or mechanical properties
    • B01F27/054—Deformable stirrers, e.g. deformed by a centrifugal force applied during operation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3017—Mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/304—Micromixers the mixing being performed in a mixing chamber where the products are brought into contact
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B18/00—Layered products essentially comprising ceramics, e.g. refractory products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/2204—Mixing chemical components in generals in order to improve chemical treatment or reactions, independently from the specific application
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/113—Propeller-shaped stirrers for producing an axial flow, e.g. shaped like a ship or aircraft propeller
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00824—Ceramic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00835—Comprising catalytically active material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00993—Design aspects
    • B01J2219/00995—Mathematical modeling
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2237/00—Aspects relating to ceramic laminates or to joining of ceramic articles with other articles by heating
    • C04B2237/30—Composition of layers of ceramic laminates or of ceramic or metallic articles to be joined by heating, e.g. Si substrates
    • C04B2237/32—Ceramic
    • C04B2237/34—Oxidic
    • C04B2237/345—Refractory metal oxides
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2237/00—Aspects relating to ceramic laminates or to joining of ceramic articles with other articles by heating
    • C04B2237/50—Processing aspects relating to ceramic laminates or to the joining of ceramic articles with other articles by heating
    • C04B2237/64—Forming laminates or joined articles comprising grooves or cuts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00—Agitating
    • Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/16—Two dimensionally sectional layer
    • Y10T428/163—Next to unitary web or sheet of equal or greater extent
    • Y10T428/164—Continuous two dimensionally sectional layer
    • Y10T428/167—Cellulosic sections [e.g., parquet floor, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/17—Three or more coplanar interfitted sections with securing means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24058—Structurally defined web or sheet [e.g., overall dimension, etc.] including grain, strips, or filamentary elements in respective layers or components in angular relation
    • Y10T428/24066—Wood grain
DE69802587T 1997-04-11 1998-03-23 Integrierte mikrokeramische chemische Anlage Expired - Fee Related DE69802587T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/835,979 US5993750A (en) 1997-04-11 1997-04-11 Integrated ceramic micro-chemical plant

Publications (2)

Publication Number Publication Date
DE69802587D1 DE69802587D1 (de) 2002-01-03
DE69802587T2 true DE69802587T2 (de) 2002-08-01

Family

ID=25270935

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802587T Expired - Fee Related DE69802587T2 (de) 1997-04-11 1998-03-23 Integrierte mikrokeramische chemische Anlage

Country Status (4)

Country Link
US (1) US5993750A (de)
EP (1) EP0870541B1 (de)
JP (1) JPH115029A (de)
DE (1) DE69802587T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018203047A1 (de) * 2018-03-01 2019-09-05 Robert Bosch Gmbh Mikrofluidische Vorrichtung

Families Citing this family (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US5842787A (en) * 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
AU747940B2 (en) * 1997-11-12 2002-05-30 Applera Corporation Serpentine electrophoresis channel with self-correcting bends
WO1999060397A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6149882A (en) * 1998-06-09 2000-11-21 Symyx Technologies, Inc. Parallel fixed bed reactor and fluid contacting apparatus
DE19832625C2 (de) * 1998-07-21 2001-05-17 Xcellsis Gmbh Verfahren zur Herstellung eines Stapelreaktors und Stapelreaktor zur Wasserstofferzeugung aus Kohlenwasserstoffen
US6592696B1 (en) 1998-10-09 2003-07-15 Motorola, Inc. Method for fabricating a multilayered structure and the structures formed by the method
EP1314472A1 (de) * 1998-10-09 2003-05-28 Motorola, Inc. Integrierte Vielschichtmikrofluidbauteile und Verfahren zu ihrer Herstellung
US6572830B1 (en) 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
US6601613B2 (en) * 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6149787A (en) * 1998-10-14 2000-11-21 Caliper Technologies Corp. External material accession systems and methods
US6240790B1 (en) * 1998-11-09 2001-06-05 Agilent Technologies, Inc. Device for high throughout sample processing, analysis and collection, and methods of use thereof
DE29903296U1 (de) * 1999-02-24 2000-08-03 Cpc Cellular Process Chemistry Mikroreaktor
US6749814B1 (en) 1999-03-03 2004-06-15 Symyx Technologies, Inc. Chemical processing microsystems comprising parallel flow microreactors and methods for using same
DK1181098T4 (da) * 1999-05-28 2011-09-26 Cepheid Patron til udførelse af en kemisk reaktion
DE19927556C2 (de) * 1999-06-16 2003-05-08 Inst Mikrotechnik Mainz Gmbh Statischer Mikromischer und Verfahren zum statischen Mischen zweier oder mehrerer Edukte
DE19927554C2 (de) 1999-06-16 2002-12-19 Inst Mikrotechnik Mainz Gmbh Mikromischer
US6642046B1 (en) 1999-12-09 2003-11-04 Motorola, Inc. Method and apparatus for performing biological reactions on a substrate surface
EP1237655A2 (de) * 1999-12-09 2002-09-11 Motorola, Inc. Vielschichtmikrofluidvorrichtungen für analyten-reaktionen
US7056477B1 (en) 2000-02-03 2006-06-06 Cellular Process Chemistry, Inc. Modular chemical production system incorporating a microreactor
US7241423B2 (en) * 2000-02-03 2007-07-10 Cellular Process Chemistry, Inc. Enhancing fluid flow in a stacked plate microreactor
US7435392B2 (en) * 2000-02-03 2008-10-14 Acclavis, Llc Scalable continuous production system
US6537506B1 (en) * 2000-02-03 2003-03-25 Cellular Process Chemistry, Inc. Miniaturized reaction apparatus
US7135266B2 (en) 2000-02-09 2006-11-14 Clariant Finance (Bvi) Limited Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias
US7485454B1 (en) 2000-03-10 2009-02-03 Bioprocessors Corp. Microreactor
US6592519B1 (en) * 2000-04-28 2003-07-15 Medtronic, Inc. Smart microfluidic device with universal coating
US7413714B1 (en) 2000-07-16 2008-08-19 Ymc Co. Ltd. Sequential reaction system
DE10036602A1 (de) * 2000-07-27 2002-02-14 Cpc Cellular Process Chemistry Mikroreaktor für Reaktionen zwischen Gasen und Flüssigkeiten
US6623860B2 (en) * 2000-10-10 2003-09-23 Aclara Biosciences, Inc. Multilevel flow structures
DE10055374B4 (de) * 2000-11-08 2006-03-02 Bartels Mikrotechnik Gmbh Verteilerplatte für Flüssigkeiten und Gase
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
DE10106953B4 (de) * 2001-02-15 2006-07-06 Cognis Ip Management Gmbh Mikroreaktoren
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US6575188B2 (en) 2001-07-26 2003-06-10 Handylab, Inc. Methods and systems for fluid control in microfluidic devices
US20020158016A1 (en) * 2001-04-26 2002-10-31 Jan Norberg Separation unit, a method for separation, and a device for mounting a separation unit in a separation apparatus
US20020174936A1 (en) * 2001-05-25 2002-11-28 Motorola, Inc. Methods for forming recessed patterns in a multilayered ceramic package and devices produced by such methods
US20030013046A1 (en) * 2001-06-29 2003-01-16 The Penn State Research Foundation, University Park, Pennsylvania Use of sacrificial layers in the manufacturing of chemical reactor structures and the application of such structures
WO2003008981A1 (fr) * 2001-07-10 2003-01-30 Kanagawa Academy Of Science And Technology Structure integree a microcanaux d'ecoulement multicouche et procede de fonctionnement d'un ecoulement multicouche a l'aide de cette derniere
EP2283924B1 (de) * 2001-08-28 2013-04-17 Gyros Patent Ab Einlass mit Mitteln zur Unterstützung der Eintritt einer Flüssigkeit in eine Mikrokanalstruktur
FR2830206B1 (fr) 2001-09-28 2004-07-23 Corning Inc Dispositif microfluidique et sa fabrication
DE10250406B4 (de) * 2001-10-30 2007-10-25 Hitachi, Ltd. Reaktionsvorrichtung und Mischsystem
US7069952B1 (en) 2001-11-14 2006-07-04 Caliper Life Sciences, Inc. Microfluidic devices and methods of their manufacture
DE10258840A1 (de) * 2002-01-28 2003-08-07 Eppendorf Ag Stapelanordnung von Reaktionsgefäßen
US20040109793A1 (en) * 2002-02-07 2004-06-10 Mcneely Michael R Three-dimensional microfluidics incorporating passive fluid control structures
JP4221184B2 (ja) * 2002-02-19 2009-02-12 日本碍子株式会社 マイクロ化学チップ
EP2302389B1 (de) * 2002-05-09 2018-01-24 The University of Chicago Einrichtung und Verfahren für Druckgesteuerten Plug-Transport und Reaktion
US6988534B2 (en) * 2002-11-01 2006-01-24 Cooligy, Inc. Method and apparatus for flexible fluid delivery for cooling desired hot spots in a heat producing device
US6994151B2 (en) 2002-10-22 2006-02-07 Cooligy, Inc. Vapor escape microchannel heat exchanger
US20040076408A1 (en) * 2002-10-22 2004-04-22 Cooligy Inc. Method and apparatus for removeably coupling a heat rejection device with a heat producing device
EP1415706B1 (de) * 2002-10-29 2017-07-12 Corning Incorporated Beschichtete Mikrostruktur und deren Herstellungsverfahren
DE10393588T5 (de) 2002-11-01 2006-02-23 Cooligy, Inc., Mountain View Optimales Ausbreitungssystem, Vorrichtung und Verfahren für flüssigkeitsgekühlten, mikroskalierten Wärmetausch
WO2004042306A2 (en) * 2002-11-01 2004-05-21 Cooligy, Inc. Method and apparatus for achieving temperature uniformity and hot spot cooling in a heat producing device
US7156159B2 (en) 2003-03-17 2007-01-02 Cooligy, Inc. Multi-level microchannel heat exchangers
US7836597B2 (en) 2002-11-01 2010-11-23 Cooligy Inc. Method of fabricating high surface to volume ratio structures and their integration in microheat exchangers for liquid cooling system
US8464781B2 (en) 2002-11-01 2013-06-18 Cooligy Inc. Cooling systems incorporating heat exchangers and thermoelectric layers
US6986382B2 (en) * 2002-11-01 2006-01-17 Cooligy Inc. Interwoven manifolds for pressure drop reduction in microchannel heat exchangers
KR100472058B1 (ko) * 2002-11-02 2005-03-11 한국전자통신연구원 미소유체 혼합을 위한 미소 유체제어 소자
US6955777B2 (en) * 2003-01-07 2005-10-18 International Business Machines Corporation Method of forming a plate for dispensing chemicals
US7090001B2 (en) 2003-01-31 2006-08-15 Cooligy, Inc. Optimized multiple heat pipe blocks for electronics cooling
WO2004092908A2 (en) * 2003-04-14 2004-10-28 Cellular Process Chemistry, Inc. System and method for determining optimal reaction parameters using continuously running process
DE10318061A1 (de) * 2003-04-17 2004-10-28 Behr Gmbh & Co. Kg Mischvorrichtung
US20040265184A1 (en) * 2003-04-18 2004-12-30 Kyocera Corporation Microchemical chip and method for producing the same
JP2004351309A (ja) * 2003-05-28 2004-12-16 Kyocera Corp マイクロ化学チップおよびその製造方法
JP2004325185A (ja) * 2003-04-23 2004-11-18 Arkray Inc 二段式検体分析用具
JP2006526407A (ja) * 2003-06-05 2006-11-24 バイオプロセッサーズ コーポレイション プロセス自動化のためのシステムおよび方法
GB0315094D0 (en) * 2003-06-27 2003-07-30 Imp College Innovations Ltd Powder injection system and method
JP2005024316A (ja) * 2003-06-30 2005-01-27 Kyocera Corp マイクロ化学チップおよびその製造方法
DE10333922B4 (de) * 2003-07-25 2005-11-17 Wella Ag Bauteile für statische Mikromischer, daraus aufgebaute Mikromischer und deren Verwendung zum Mischen, zum Dispergieren oder zur Durchführung chemischer Reaktionen
WO2005011867A2 (en) 2003-07-31 2005-02-10 Handylab, Inc. Processing particle-containing samples
DE10335068A1 (de) * 2003-07-31 2005-03-03 Dahlbeck, Rolf, Dr.-Ing. Mikroreaktormodul
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US20050069462A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfluidics Packaging
US20050069949A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfabricated Fluidic Structures
US20050077657A1 (en) * 2003-10-14 2005-04-14 International Business Machines Corporation A Method of Making a Multichannel and Multilayer Pharmaceutical Device
US8066955B2 (en) * 2003-10-17 2011-11-29 James M. Pinchot Processing apparatus fabrication
US6994245B2 (en) * 2003-10-17 2006-02-07 James M. Pinchot Micro-reactor fabrication
US20050084072A1 (en) * 2003-10-17 2005-04-21 Jmp Industries, Inc., An Ohio Corporation Collimator fabrication
JP4632653B2 (ja) * 2003-10-24 2011-02-16 京セラ株式会社 多層配線基板
EP1703968A1 (de) * 2003-12-16 2006-09-27 Unilever Plc Mikrofluidische vorrichtung
US7470408B2 (en) * 2003-12-18 2008-12-30 Velocys In situ mixing in microchannels
US7618811B2 (en) * 2004-02-24 2009-11-17 Thermal Gradient Thermal cycling device
EP1757926B1 (de) * 2004-04-28 2019-04-10 ARKRAY, Inc. Elektrophoresechip und elektrophoresevorrichtung damit
CA2994321C (en) 2004-05-03 2023-08-08 Handylab, Inc. A microfluidic device and methods for processing polynucleotide-containing samples
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
US20070140042A1 (en) * 2004-06-04 2007-06-21 Gerhard Schanz Multicomponent packaging with static micromixer
US7645423B2 (en) * 2004-08-20 2010-01-12 International Business Machines Corporation Optical micro plugs for multichannel and multilayer pharmaceutical device
JP2006187684A (ja) * 2004-12-28 2006-07-20 Fuji Xerox Co Ltd マイクロ流体素子
DE102005004075B4 (de) * 2005-01-28 2008-04-03 Umicore Ag & Co. Kg Keramischer Mikroreaktor
US7228735B2 (en) * 2005-02-03 2007-06-12 Integrated Sensing Systems, Inc. Fluid sensing device with integrated bypass and process therefor
FR2885898B1 (fr) * 2005-05-17 2007-07-06 Commissariat Energie Atomique Composant microfluidique comprenant au moins un canal rempli de nanotubes et procede de fabrication d'un tel composant microfluidique.
JP4590558B2 (ja) * 2005-05-20 2010-12-01 国立大学法人 東京大学 流体混合装置
WO2006127056A2 (en) * 2005-05-25 2006-11-30 Bio-Rad Laboratories, Inc. Fluidics device
US20060272713A1 (en) * 2005-05-31 2006-12-07 Garner Sean M Microfluidic devices with integrated tubular structures
US20090268548A1 (en) * 2005-08-11 2009-10-29 Eksigent Technologies, Llc Microfluidic systems, devices and methods for reducing diffusion and compliance effects at a fluid mixing region
KR100691274B1 (ko) 2005-08-24 2007-03-12 삼성전기주식회사 박형 개질 기
SE529516C2 (sv) * 2005-10-24 2007-09-04 Alfa Laval Corp Ab Universell flödesmodul
DE102005051637A1 (de) * 2005-10-26 2007-05-03 Atotech Deutschland Gmbh Reaktorsystem mit einem mikrostrukturierten Reaktor sowie Verfahren zur Durchführung einer chemischen Reaktion in einem solchen Reaktor
SE530820C2 (sv) * 2005-12-22 2008-09-16 Alfa Laval Corp Ab Ett mixningssystem för värmeväxlare
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
DK3088083T3 (en) 2006-03-24 2018-11-26 Handylab Inc Method of carrying out PCR down a multi-track cartridge
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US8157001B2 (en) 2006-03-30 2012-04-17 Cooligy Inc. Integrated liquid to air conduction module
US7715194B2 (en) 2006-04-11 2010-05-11 Cooligy Inc. Methodology of cooling multiple heat sources in a personal computer through the use of multiple fluid-based heat exchanging loops coupled via modular bus-type heat exchangers
JP2007044692A (ja) * 2006-09-27 2007-02-22 Japan Science & Technology Agency ダブルエマルション・マイクロカプセル生成装置
EP2091647A2 (de) 2006-11-14 2009-08-26 Handylab, Inc. Mikrofluidisches system für parallele amplifikation und erkennung von polynukleotiden
FR2913109B1 (fr) * 2007-02-27 2009-05-01 Boostec Sa Procede de fabrication d'un dispositif de type echangeur de chaleur en ceramique et dispositifs obtenus par le procede.
DE102007020888A1 (de) * 2007-05-04 2008-11-06 Micro Systems Engineering Gmbh & Co. Kg Keramisches Substratmaterial, Verfahren zur Herstellung und Verwendung desselben sowie Antenne oder Antennenarray
US8476382B2 (en) * 2007-06-05 2013-07-02 Eugenia Kumacheva Multiple continuous microfluidic reactors for the scaled up synthesis of gel or polymer particles
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8324372B2 (en) 2007-07-13 2012-12-04 Handylab, Inc. Polynucleotide capture materials, and methods of using same
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US20090036303A1 (en) * 2007-07-30 2009-02-05 Motorola, Inc. Method of forming a co-fired ceramic apparatus including a micro-reader
TW200934352A (en) 2007-08-07 2009-08-01 Cooligy Inc Internal access mechanism for a server rack
PE20090965A1 (es) 2007-10-12 2009-07-13 Bigtec Private Ltd Micro chip
DE102007049172A1 (de) * 2007-10-13 2009-04-16 Micro Systems Engineering Gmbh & Co. Kg Mikroreaktor und Verfahren zur Herstellung eines solchen sowie Verfahren zur Herstellung eines Substrats für einen Mikroreaktor
US20090188097A1 (en) * 2008-01-25 2009-07-30 Siemens Power Generation, Inc. Method of layered fabrication
US8250877B2 (en) 2008-03-10 2012-08-28 Cooligy Inc. Device and methodology for the removal of heat from an equipment rack by means of heat exchangers mounted to a door
US9297571B1 (en) 2008-03-10 2016-03-29 Liebert Corporation Device and methodology for the removal of heat from an equipment rack by means of heat exchangers mounted to a door
JP4683066B2 (ja) * 2008-04-14 2011-05-11 コニカミノルタホールディングス株式会社 液体混合機構
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
DE102008043352A1 (de) * 2008-10-31 2010-05-06 Micro Systems Engineering Gmbh Keramisches Substratmaterial, Verfahren zur Herstellung und Verwendung desselben sowie Antenne oder Antennenarray
CN101429560B (zh) * 2008-12-19 2012-02-08 清华大学 一种定量聚合酶链式反应检测装置及其制备方法
TW201103626A (en) * 2009-04-28 2011-02-01 Corning Inc Microreactors with connectors sealed thereon; their manufacture
FR2951858B1 (fr) * 2009-10-26 2011-12-23 Areva T & D Sas Dispositif de refroidissement d'un appareil moyenne tension utilisant des caloducs isoles
CN101922870B (zh) * 2010-08-31 2013-02-27 东南大学 一种间壁式换热器
CN102080937A (zh) * 2011-01-28 2011-06-01 东南大学 工形树状式交叉流换热器
BR112013026451B1 (pt) 2011-04-15 2021-02-09 Becton, Dickinson And Company sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação
EP2720795A4 (de) * 2011-06-14 2015-04-29 Idex Health & Science Llc Verstopfungssicherer strömungsweg
CA2850412A1 (en) * 2011-09-30 2013-04-04 The University Of British Columbia Methods and apparatus for flow-controlled wetting
JP6117217B2 (ja) 2011-09-30 2017-04-19 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ ユニット化された試薬ストリップ
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
US10822644B2 (en) 2012-02-03 2020-11-03 Becton, Dickinson And Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
EP3427830B1 (de) 2012-10-24 2021-06-23 Genmark Diagnostics Inc. Integrierte multiplex-zielanalyse
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US9222623B2 (en) 2013-03-15 2015-12-29 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
GB2514614A (en) * 2013-05-31 2014-12-03 Simon Johnson Chemical process apparatus and methods
DE102013012731A1 (de) 2013-08-01 2015-02-05 Krohne Messtechnik Gmbh Verfahren zur Herstellung eines Gaskonverters und entsprechender Gaskonverter
CN103977720B (zh) * 2013-09-10 2016-01-13 中国中化股份有限公司 一种组合式层状流体配分混合装置及其应用
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
ITTO20131057A1 (it) * 2013-12-20 2015-06-21 Consiglio Nazionale Ricerche Apparecchiatura per la rilevazione della presenza di un analita in un campione di sostanza, in particolare di prodotto alimentare
JP2017523043A (ja) 2014-05-30 2017-08-17 マイクロフルーイディクス インターナショナル コーポレイション キャビテーションが低減された相互作用チャンバ
AU2015346527A1 (en) * 2014-11-11 2017-06-29 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
JP6409556B2 (ja) * 2014-12-19 2018-10-24 富士通株式会社 冷却機構付き基板及び電子機器
US10859563B2 (en) * 2015-12-01 2020-12-08 General Electric Company Erythrocyte aggregation and leukocyte isolation
GB201617354D0 (en) * 2016-10-13 2016-11-30 Blacktrace Holdings Limited A device for receiving fluid
JP2023508249A (ja) * 2019-12-23 2023-03-01 ナットクラッカー セラピューティクス， インコーポレイテッド マイクロ流体装置及びその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881701A (en) * 1973-09-17 1975-05-06 Aerojet General Co Fluid mixer reactor
US4392362A (en) * 1979-03-23 1983-07-12 The Board Of Trustees Of The Leland Stanford Junior University Micro miniature refrigerators
US4386505A (en) * 1981-05-01 1983-06-07 The Board Of Trustees Of The Leland Stanford Junior University Refrigerators
US4516632A (en) * 1982-08-31 1985-05-14 The United States Of America As Represented By The United States Deparment Of Energy Microchannel crossflow fluid heat exchanger and method for its fabrication
DE3926466C2 (de) * 1989-08-10 1996-12-19 Christoph Dipl Ing Caesar Mikroreaktor zur Durchführung chemischer Reaktionen von zwei chemischen Stoffen mit starker Wärmetönung
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
US5209906A (en) * 1991-05-10 1993-05-11 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Modular isothermal reactor
US5265327A (en) * 1991-09-13 1993-11-30 Faris Sadeg M Microchannel plate technology
US5534328A (en) * 1993-12-02 1996-07-09 E. I. Du Pont De Nemours And Company Integrated chemical processing apparatus and processes for the preparation thereof
US5595712A (en) * 1994-07-25 1997-01-21 E. I. Du Pont De Nemours And Company Chemical mixing and reaction apparatus
US5611214A (en) * 1994-07-29 1997-03-18 Battelle Memorial Institute Microcomponent sheet architecture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018203047A1 (de) * 2018-03-01 2019-09-05 Robert Bosch Gmbh Mikrofluidische Vorrichtung

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DE69802587D1 (de) 2002-01-03
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