DE69723984D1 - Inhibitoren der produktion von s-cd23 und der secretion von tnf - Google Patents
Inhibitoren der produktion von s-cd23 und der secretion von tnfInfo
- Publication number
- DE69723984D1 DE69723984D1 DE69723984T DE69723984T DE69723984D1 DE 69723984 D1 DE69723984 D1 DE 69723984D1 DE 69723984 T DE69723984 T DE 69723984T DE 69723984 T DE69723984 T DE 69723984T DE 69723984 D1 DE69723984 D1 DE 69723984D1
- Authority
- DE
- Germany
- Prior art keywords
- tnf
- secretion
- inhibitors
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9609794 | 1996-05-10 | ||
GBGB9609794.4A GB9609794D0 (en) | 1996-05-10 | 1996-05-10 | Novel compounds |
PCT/EP1997/002433 WO1997043249A1 (en) | 1996-05-10 | 1997-05-06 | INHIBITORS OF THE PRODUCTION OF s-CD23 AND THE SECRETION OF TNF |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69723984D1 true DE69723984D1 (de) | 2003-09-11 |
DE69723984T2 DE69723984T2 (de) | 2004-06-09 |
Family
ID=10793494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69723984T Expired - Fee Related DE69723984T2 (de) | 1996-05-10 | 1997-05-06 | Inhibitoren der produktion von s-cd23 und der secretion von tnf |
Country Status (21)
Country | Link |
---|---|
US (1) | US6235753B1 (de) |
EP (1) | EP0918747B1 (de) |
JP (1) | JP2000510473A (de) |
KR (1) | KR20000010892A (de) |
AR (1) | AR007060A1 (de) |
AT (1) | ATE246673T1 (de) |
AU (1) | AU2897397A (de) |
BR (1) | BR9709450A (de) |
CA (1) | CA2253590A1 (de) |
CO (1) | CO4990945A1 (de) |
CZ (1) | CZ363198A3 (de) |
DE (1) | DE69723984T2 (de) |
ES (1) | ES2205218T3 (de) |
GB (1) | GB9609794D0 (de) |
IL (1) | IL126860A0 (de) |
NO (1) | NO985214L (de) |
NZ (1) | NZ332628A (de) |
PL (1) | PL329855A1 (de) |
TR (1) | TR199802271T2 (de) |
WO (1) | WO1997043249A1 (de) |
ZA (1) | ZA973964B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020082200A1 (en) * | 1994-07-13 | 2002-06-27 | Smithkline Beecham P.1.C. | Use of inhibitors of human S-CD23 |
US6548084B2 (en) | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
AUPO721997A0 (en) * | 1997-06-06 | 1997-07-03 | Queensland Institute Of Medical Research, The | Anticancer compounds |
EP1030851B1 (de) * | 1997-11-12 | 2005-01-12 | Darwin Discovery Limited | Hydroxam- und carbonsäurederivate mit mmp- und tnf-hemmender aktivität |
GB9813451D0 (en) * | 1998-06-22 | 1998-08-19 | Smithkline Beecham Plc | Novel compounds |
GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
US6541661B1 (en) | 1999-11-23 | 2003-04-01 | Methylgene, Inc. | Inhibitors of histone deacetylase |
GB9930754D0 (en) * | 1999-12-29 | 2000-02-16 | Smithkline Beecham Plc | Novel compounds |
US7652036B2 (en) | 2003-02-25 | 2010-01-26 | Topotarget Uk Limited | Carbamic acid compounds comprising a bicyclic heteroaryl group as HDAC inhibitors |
GB0818907D0 (en) * | 2008-10-15 | 2008-11-19 | Isis Innovation | Histone lysine demethylase inhibitors |
SG176010A1 (en) | 2009-05-28 | 2011-12-29 | Novartis Ag | Substituted aminobutyric derivatives as neprilysin inhibitors |
AU2010251967B9 (en) * | 2009-05-28 | 2014-04-03 | Novartis Ag | Substituted aminopropionic derivatives as neprilysin inhibitors |
US8945575B2 (en) | 2009-12-01 | 2015-02-03 | Trustees Of Boston University | Treatment of IgE-mediated disease |
JP6295277B2 (ja) | 2013-02-14 | 2018-03-14 | ノバルティス アーゲー | Nep(中性エンドペプチダーゼ)阻害剤としての置換ビスフェニルブタン酸ホスホン酸誘導体 |
CA2900226A1 (en) | 2013-02-14 | 2014-08-21 | Novartis Ag | Substituted bisphenyl butanoic acid derivatives as nep inhibitors with improved in vivo efficacy |
CA2963875A1 (en) * | 2014-11-19 | 2016-05-26 | Actelion Pharmaceuticals Ltd | Antibacterial benzothiazole derivatives |
CN113194954A (zh) | 2018-10-04 | 2021-07-30 | 国家医疗保健研究所 | 用于治疗角皮病的egfr抑制剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9215665D0 (en) * | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
ES2144819T3 (es) * | 1994-01-20 | 2000-06-16 | British Biotech Pharm | L-terc-leucina-2-piridilamida. |
GB9414157D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
US5562917A (en) | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
DE19506492C2 (de) | 1995-02-24 | 2003-05-08 | Focke & Co | Einrichtung zum Speichern von Zigaretten oder dergleichen |
US5570079A (en) | 1995-04-24 | 1996-10-29 | Dockery; Devan | Home security system for detecting an intrusion into a monitored area by an infrared detector |
-
1996
- 1996-05-10 GB GBGB9609794.4A patent/GB9609794D0/en active Pending
-
1997
- 1997-05-06 ES ES97923064T patent/ES2205218T3/es not_active Expired - Lifetime
- 1997-05-06 KR KR1019980709039A patent/KR20000010892A/ko not_active Application Discontinuation
- 1997-05-06 NZ NZ332628A patent/NZ332628A/en unknown
- 1997-05-06 EP EP97923064A patent/EP0918747B1/de not_active Expired - Lifetime
- 1997-05-06 BR BR9709450A patent/BR9709450A/pt not_active Application Discontinuation
- 1997-05-06 CZ CZ983631A patent/CZ363198A3/cs unknown
- 1997-05-06 DE DE69723984T patent/DE69723984T2/de not_active Expired - Fee Related
- 1997-05-06 PL PL97329855A patent/PL329855A1/xx unknown
- 1997-05-06 AU AU28973/97A patent/AU2897397A/en not_active Abandoned
- 1997-05-06 TR TR1998/02271T patent/TR199802271T2/xx unknown
- 1997-05-06 WO PCT/EP1997/002433 patent/WO1997043249A1/en not_active Application Discontinuation
- 1997-05-06 IL IL12686097A patent/IL126860A0/xx unknown
- 1997-05-06 US US09/180,547 patent/US6235753B1/en not_active Expired - Fee Related
- 1997-05-06 CA CA002253590A patent/CA2253590A1/en not_active Abandoned
- 1997-05-06 JP JP09540514A patent/JP2000510473A/ja not_active Ceased
- 1997-05-06 AT AT97923064T patent/ATE246673T1/de not_active IP Right Cessation
- 1997-05-08 ZA ZA973964A patent/ZA973964B/xx unknown
- 1997-05-08 AR ARP970101926A patent/AR007060A1/es not_active Application Discontinuation
- 1997-05-09 CO CO97025078A patent/CO4990945A1/es unknown
-
1998
- 1998-11-09 NO NO985214A patent/NO985214L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0918747A1 (de) | 1999-06-02 |
PL329855A1 (en) | 1999-04-12 |
JP2000510473A (ja) | 2000-08-15 |
NO985214D0 (no) | 1998-11-09 |
CZ363198A3 (cs) | 1999-06-16 |
WO1997043249A1 (en) | 1997-11-20 |
NO985214L (no) | 1998-12-01 |
CO4990945A1 (es) | 2000-12-26 |
BR9709450A (pt) | 1999-08-10 |
US6235753B1 (en) | 2001-05-22 |
TR199802271T2 (xx) | 2000-08-21 |
KR20000010892A (ko) | 2000-02-25 |
AR007060A1 (es) | 1999-10-13 |
AU2897397A (en) | 1997-12-05 |
ES2205218T3 (es) | 2004-05-01 |
ZA973964B (en) | 1998-11-09 |
IL126860A0 (en) | 1999-09-22 |
CA2253590A1 (en) | 1997-11-20 |
DE69723984T2 (de) | 2004-06-09 |
GB9609794D0 (en) | 1996-07-17 |
EP0918747B1 (de) | 2003-08-06 |
ATE246673T1 (de) | 2003-08-15 |
NZ332628A (en) | 2000-06-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69723984D1 (de) | Inhibitoren der produktion von s-cd23 und der secretion von tnf | |
NO960552D0 (no) | Elektrode og fremstilling av elektroden | |
DE69820397D1 (de) | Ätzmittel und ihre Verwendung | |
NO991433D0 (no) | Heterosykliske estere og amider | |
NO180145C (no) | Tannbörste og tildannelse av samme | |
DE69821072D1 (de) | Echtzeit bildgesteuerte Positionierung von Verankerungseinheiten | |
DK0791190T3 (da) | Signaleringsgenstande og fremgangsmåde til fremstilling af samme | |
DE69738197D1 (de) | Azolotriazine und pyrimidine | |
NO975245L (no) | Heterocykluser som inhibitorer av leukosyttadhesjon og VLA-4-antagonister | |
DE69703584D1 (de) | Kaskadierter anschluss von kommunizierenden geräte | |
FI960803A0 (fi) | TNF-alfa-sekreetion inhibiittoreita | |
PL333505A1 (en) | Benzamido-aldehydes and their application as inhibitors of cysteinic proteases | |
DE69411692T2 (de) | Mittel zur Förderung der Proliferationen von Bifidobacterium | |
FI963655A0 (fi) | Polypeptidien parannettu eritys | |
NO984094D0 (no) | Utladningsreaktor og anvendelse av samme | |
DE69501493T2 (de) | Entfernung von Feuchtigkeit und Passivierung von Oberflächen | |
FI980246A0 (fi) | Menetelmä keittimen käyttämiseksi ja keitin | |
DE69716556D1 (de) | Längsgestreckter Vliesstoff und dessen Herstellungsverfahren | |
DE69737335D1 (de) | Festelektrolytkondensator und dessen Herstellungsverfahren | |
DE69717677T2 (de) | Koproduktion von perfluormethylperfluorvinylether und perfluorethylperfluorvinylether | |
DE69524590T2 (de) | Zusammensetzung von 5htida und 5htid antagonisten | |
DE69731897D1 (de) | Decken-einbau von beleuchtungs- oder anderen geräten | |
IS5356A (is) | Viss bensóþíasíndíoxíð-mótlyf gegn endóþelíni og ferli til að smíða þau | |
DE59700145D1 (de) | Trainingsstation und Verwendung der Trainingsstation | |
DE69732095D1 (de) | Ionomerzusammensetzung und ihre verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |