NO985214D0 - Inhibitorer for produksjon av s-CD23 og sekresjon av TNF - Google Patents

Inhibitorer for produksjon av s-CD23 og sekresjon av TNF

Info

Publication number
NO985214D0
NO985214D0 NO985214A NO985214A NO985214D0 NO 985214 D0 NO985214 D0 NO 985214D0 NO 985214 A NO985214 A NO 985214A NO 985214 A NO985214 A NO 985214A NO 985214 D0 NO985214 D0 NO 985214D0
Authority
NO
Norway
Prior art keywords
tnf
secretion
inhibitors
production
Prior art date
Application number
NO985214A
Other languages
English (en)
Other versions
NO985214L (no
Inventor
Stuart Bailey
Derek Richard Buckle
Andrew Faller
David Glynn Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO985214D0 publication Critical patent/NO985214D0/no
Publication of NO985214L publication Critical patent/NO985214L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO985214A 1996-05-10 1998-11-09 Inhibitorer for produksjon av s-CD23 og sekresjon av TNF NO985214L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9609794.4A GB9609794D0 (en) 1996-05-10 1996-05-10 Novel compounds
PCT/EP1997/002433 WO1997043249A1 (en) 1996-05-10 1997-05-06 INHIBITORS OF THE PRODUCTION OF s-CD23 AND THE SECRETION OF TNF

Publications (2)

Publication Number Publication Date
NO985214D0 true NO985214D0 (no) 1998-11-09
NO985214L NO985214L (no) 1998-12-01

Family

ID=10793494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985214A NO985214L (no) 1996-05-10 1998-11-09 Inhibitorer for produksjon av s-CD23 og sekresjon av TNF

Country Status (21)

Country Link
US (1) US6235753B1 (no)
EP (1) EP0918747B1 (no)
JP (1) JP2000510473A (no)
KR (1) KR20000010892A (no)
AR (1) AR007060A1 (no)
AT (1) ATE246673T1 (no)
AU (1) AU2897397A (no)
BR (1) BR9709450A (no)
CA (1) CA2253590A1 (no)
CO (1) CO4990945A1 (no)
CZ (1) CZ363198A3 (no)
DE (1) DE69723984T2 (no)
ES (1) ES2205218T3 (no)
GB (1) GB9609794D0 (no)
IL (1) IL126860A0 (no)
NO (1) NO985214L (no)
NZ (1) NZ332628A (no)
PL (1) PL329855A1 (no)
TR (1) TR199802271T2 (no)
WO (1) WO1997043249A1 (no)
ZA (1) ZA973964B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020082200A1 (en) * 1994-07-13 2002-06-27 Smithkline Beecham P.1.C. Use of inhibitors of human S-CD23
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
AUPO721997A0 (en) * 1997-06-06 1997-07-03 Queensland Institute Of Medical Research, The Anticancer compounds
ATE286892T1 (de) 1997-11-12 2005-01-15 Darwin Discovery Ltd Hydroxam- und carbonsäurederivate mit mmp- und tnf-hemmender aktivität
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds
GB9922825D0 (en) * 1999-09-25 1999-11-24 Smithkline Beecham Biolog Medical use
KR20020070285A (ko) 1999-11-23 2002-09-05 메틸진, 인크. 히스톤 디아세틸라제의 억제제
GB9930754D0 (en) * 1999-12-29 2000-02-16 Smithkline Beecham Plc Novel compounds
CA2516842A1 (en) * 2003-02-25 2004-09-10 Topotarget Uk Limited Hydroxamic acid compounds comprising a bicylic heteroaryl group as hdac inhibitors
GB0818907D0 (en) * 2008-10-15 2008-11-19 Isis Innovation Histone lysine demethylase inhibitors
CA2763565A1 (en) 2009-05-28 2010-12-02 Novartis Ag Substituted aminobutyric derivatives as neprilysin inhibitors
ES2523734T3 (es) * 2009-05-28 2014-12-01 Novartis Ag Derivados aminopropiónicos sustituidos como inhibidores de neprilisina
US8945575B2 (en) 2009-12-01 2015-02-03 Trustees Of Boston University Treatment of IgE-mediated disease
CN105008337B (zh) 2013-02-14 2017-08-04 诺华股份有限公司 具有改善的体内功效的作为nep抑制剂的取代的联苯基丁酸衍生物
LT2956464T (lt) 2013-02-14 2018-07-10 Novartis Ag Pakeisti bisfenilbutanoinės fosfonrūgšties dariniai, kaip nep (neutralios endopeptidazės) inhibitoriai
CA2963875A1 (en) * 2014-11-19 2016-05-26 Actelion Pharmaceuticals Ltd Antibacterial benzothiazole derivatives
CA3115038A1 (en) 2018-10-04 2020-04-09 Inserm (Institut National De La Sante Et De La Recherche Medicale) Egfr inhibitors for treating keratodermas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215665D0 (en) * 1992-07-23 1992-09-09 British Bio Technology Compounds
DE69515702T2 (de) * 1994-01-20 2000-08-10 British Biotech Pharm L-Tertiär-leucin-2-pyridylamid
GB9414157D0 (en) * 1994-07-13 1994-08-31 Smithkline Beecham Plc Medical use
US5562917A (en) 1994-12-23 1996-10-08 Pentech Pharmaceuticals, Inc. Transdermal administration of apomorphine
DE19506492C2 (de) 1995-02-24 2003-05-08 Focke & Co Einrichtung zum Speichern von Zigaretten oder dergleichen
US5570079A (en) 1995-04-24 1996-10-29 Dockery; Devan Home security system for detecting an intrusion into a monitored area by an infrared detector

Also Published As

Publication number Publication date
PL329855A1 (en) 1999-04-12
CA2253590A1 (en) 1997-11-20
BR9709450A (pt) 1999-08-10
KR20000010892A (ko) 2000-02-25
AR007060A1 (es) 1999-10-13
NO985214L (no) 1998-12-01
CZ363198A3 (cs) 1999-06-16
ATE246673T1 (de) 2003-08-15
DE69723984T2 (de) 2004-06-09
EP0918747B1 (en) 2003-08-06
NZ332628A (en) 2000-06-23
AU2897397A (en) 1997-12-05
ZA973964B (en) 1998-11-09
WO1997043249A1 (en) 1997-11-20
IL126860A0 (en) 1999-09-22
JP2000510473A (ja) 2000-08-15
US6235753B1 (en) 2001-05-22
EP0918747A1 (en) 1999-06-02
GB9609794D0 (en) 1996-07-17
TR199802271T2 (xx) 2000-08-21
DE69723984D1 (de) 2003-09-11
CO4990945A1 (es) 2000-12-26
ES2205218T3 (es) 2004-05-01

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