DE69723926T2 - Verfahren zur synthese von gm2 - Google Patents

Verfahren zur synthese von gm2 Download PDF

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Publication number
DE69723926T2
DE69723926T2 DE69723926T DE69723926T DE69723926T2 DE 69723926 T2 DE69723926 T2 DE 69723926T2 DE 69723926 T DE69723926 T DE 69723926T DE 69723926 T DE69723926 T DE 69723926T DE 69723926 T2 DE69723926 T2 DE 69723926T2
Authority
DE
Germany
Prior art keywords
compound
group
benzyl
pivaloyl
vib
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69723926T
Other languages
German (de)
English (en)
Other versions
DE69723926D1 (de
Inventor
Richard Schmidt
Julio C. Castro-Palomino
Andreas Doll
Gerd Ritter
Lloyd J. Old
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Cancer Research
Original Assignee
Ludwig Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Cancer Research filed Critical Ludwig Cancer Research
Publication of DE69723926D1 publication Critical patent/DE69723926D1/de
Application granted granted Critical
Publication of DE69723926T2 publication Critical patent/DE69723926T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lock And Its Accessories (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Glass Compositions (AREA)
  • Catalysts (AREA)
DE69723926T 1996-02-16 1997-02-05 Verfahren zur synthese von gm2 Expired - Fee Related DE69723926T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/602,580 US5756695A (en) 1996-02-16 1996-02-16 Methods of synthesizing GM2
US602580 1996-02-16
PCT/US1997/001944 WO1997030061A1 (en) 1996-02-16 1997-02-05 Methods of synthesizing gm2

Publications (2)

Publication Number Publication Date
DE69723926D1 DE69723926D1 (de) 2003-09-11
DE69723926T2 true DE69723926T2 (de) 2004-07-15

Family

ID=24411928

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69723926T Expired - Fee Related DE69723926T2 (de) 1996-02-16 1997-02-05 Verfahren zur synthese von gm2

Country Status (8)

Country Link
US (1) US5756695A (enExample)
EP (1) EP0821691B1 (enExample)
JP (2) JP3220704B2 (enExample)
AT (1) ATE246697T1 (enExample)
AU (1) AU712149B2 (enExample)
CA (1) CA2217708A1 (enExample)
DE (1) DE69723926T2 (enExample)
WO (1) WO1997030061A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977329A (en) * 1996-02-16 1999-11-02 Ludwig Institute For Cancer Research Methods of synthesizing GM3
US5951317A (en) * 1998-04-13 1999-09-14 Motorola, Inc. Accessory connector assembly
CN1300158C (zh) * 2005-03-22 2007-02-14 重庆邮电学院 一类非天然活性寡糖类化合物及其制备方法和应用
WO2011053614A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Crystalline cdm-nag and methods for producing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds

Also Published As

Publication number Publication date
DE69723926D1 (de) 2003-09-11
JP2001316397A (ja) 2001-11-13
AU1858697A (en) 1997-09-02
EP0821691A4 (en) 2001-10-04
US5756695A (en) 1998-05-26
EP0821691B1 (en) 2003-08-06
AU712149B2 (en) 1999-10-28
CA2217708A1 (en) 1997-08-21
JP3220704B2 (ja) 2001-10-22
ATE246697T1 (de) 2003-08-15
JPH11504348A (ja) 1999-04-20
EP0821691A1 (en) 1998-02-04
WO1997030061A1 (en) 1997-08-21

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee