JP3220704B2 - Ｇｍ２の合成方法 - Google Patents

Ｇｍ２の合成方法

Info

Publication number
JP3220704B2
JP3220704B2 JP52939897A JP52939897A JP3220704B2 JP 3220704 B2 JP3220704 B2 JP 3220704B2 JP 52939897 A JP52939897 A JP 52939897A JP 52939897 A JP52939897 A JP 52939897A JP 3220704 B2 JP3220704 B2 JP 3220704B2
Authority
JP
Japan
Prior art keywords
compound
mmol
group
acetyl
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP52939897A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11504348A (ja
Inventor
シュミット，リヒャルト
カストロ，パロミノ，ユリオ，ツェー
ドール，アンドレアス
リッター，ゲルト
オールド，ロイド，ジェイ
Original Assignee
ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ filed Critical ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ
Publication of JPH11504348A publication Critical patent/JPH11504348A/ja
Application granted granted Critical
Publication of JP3220704B2 publication Critical patent/JP3220704B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lock And Its Accessories (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Glass Compositions (AREA)
  • Catalysts (AREA)
JP52939897A 1996-02-16 1997-02-05 Ｇｍ２の合成方法 Expired - Fee Related JP3220704B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/602,580 US5756695A (en) 1996-02-16 1996-02-16 Methods of synthesizing GM2
US08/602,580 1996-02-16
PCT/US1997/001944 WO1997030061A1 (en) 1996-02-16 1997-02-05 Methods of synthesizing gm2

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2001145749A Division JP2001316397A (ja) 1996-02-16 2001-05-16 Ｇｍ２の合成方法

Publications (2)

Publication Number Publication Date
JPH11504348A JPH11504348A (ja) 1999-04-20
JP3220704B2 true JP3220704B2 (ja) 2001-10-22

Family

ID=24411928

Family Applications (2)

Application Number Title Priority Date Filing Date
JP52939897A Expired - Fee Related JP3220704B2 (ja) 1996-02-16 1997-02-05 Ｇｍ２の合成方法
JP2001145749A Pending JP2001316397A (ja) 1996-02-16 2001-05-16 Ｇｍ２の合成方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2001145749A Pending JP2001316397A (ja) 1996-02-16 2001-05-16 Ｇｍ２の合成方法

Country Status (8)

Country Link
US (1) US5756695A (enExample)
EP (1) EP0821691B1 (enExample)
JP (2) JP3220704B2 (enExample)
AT (1) ATE246697T1 (enExample)
AU (1) AU712149B2 (enExample)
CA (1) CA2217708A1 (enExample)
DE (1) DE69723926T2 (enExample)
WO (1) WO1997030061A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977329A (en) * 1996-02-16 1999-11-02 Ludwig Institute For Cancer Research Methods of synthesizing GM3
US5951317A (en) * 1998-04-13 1999-09-14 Motorola, Inc. Accessory connector assembly
CN1300158C (zh) * 2005-03-22 2007-02-14 重庆邮电学院 一类非天然活性寡糖类化合物及其制备方法和应用
WO2011053614A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Crystalline cdm-nag and methods for producing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ｃａｒｂｏｈｙｄｒａｔｅ Ｒｅｓｅａｒｃｈ，Ｖｏｌ．１５６（１９８６）ｐ．ｃ１−ｃ５
Ｃａｒｂｏｈｙｄｒａｔｅ Ｒｅｓｅａｒｃｈ，Ｖｏｌ．２８０（ＪＡＮＵＡＲＹ １１ｔｈ，１９９６）ｐ．２５１−２６０
Ｇｌｙｃｏｃｏｎｊｕｇａｔｅ Ｊｏｕｒｎａｌ，Ｖｏｌ．１０（１９９３）ｐ．１６−２５

Also Published As

Publication number Publication date
DE69723926D1 (de) 2003-09-11
JP2001316397A (ja) 2001-11-13
DE69723926T2 (de) 2004-07-15
AU1858697A (en) 1997-09-02
EP0821691A4 (en) 2001-10-04
US5756695A (en) 1998-05-26
EP0821691B1 (en) 2003-08-06
AU712149B2 (en) 1999-10-28
CA2217708A1 (en) 1997-08-21
ATE246697T1 (de) 2003-08-15
JPH11504348A (ja) 1999-04-20
EP0821691A1 (en) 1998-02-04
WO1997030061A1 (en) 1997-08-21

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