ATE246697T1 - Verfahren zur synthese von gm2 - Google Patents

Verfahren zur synthese von gm2

Info

Publication number
ATE246697T1
ATE246697T1 AT97904258T AT97904258T ATE246697T1 AT E246697 T1 ATE246697 T1 AT E246697T1 AT 97904258 T AT97904258 T AT 97904258T AT 97904258 T AT97904258 T AT 97904258T AT E246697 T1 ATE246697 T1 AT E246697T1
Authority
AT
Austria
Prior art keywords
synthesis
gm2s
methods
efficient
result
Prior art date
Application number
AT97904258T
Other languages
German (de)
English (en)
Inventor
Richard Schmidt
Julio C Castro-Palomino
Andreas Doll
Gerd Ritter
Lloyd J Old
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Application granted granted Critical
Publication of ATE246697T1 publication Critical patent/ATE246697T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lock And Its Accessories (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Catalysts (AREA)
  • Glass Compositions (AREA)
AT97904258T 1996-02-16 1997-02-05 Verfahren zur synthese von gm2 ATE246697T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/602,580 US5756695A (en) 1996-02-16 1996-02-16 Methods of synthesizing GM2
PCT/US1997/001944 WO1997030061A1 (en) 1996-02-16 1997-02-05 Methods of synthesizing gm2

Publications (1)

Publication Number Publication Date
ATE246697T1 true ATE246697T1 (de) 2003-08-15

Family

ID=24411928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97904258T ATE246697T1 (de) 1996-02-16 1997-02-05 Verfahren zur synthese von gm2

Country Status (8)

Country Link
US (1) US5756695A (enExample)
EP (1) EP0821691B1 (enExample)
JP (2) JP3220704B2 (enExample)
AT (1) ATE246697T1 (enExample)
AU (1) AU712149B2 (enExample)
CA (1) CA2217708A1 (enExample)
DE (1) DE69723926T2 (enExample)
WO (1) WO1997030061A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977329A (en) * 1996-02-16 1999-11-02 Ludwig Institute For Cancer Research Methods of synthesizing GM3
US5951317A (en) * 1998-04-13 1999-09-14 Motorola, Inc. Accessory connector assembly
CN1300158C (zh) * 2005-03-22 2007-02-14 重庆邮电学院 一类非天然活性寡糖类化合物及其制备方法和应用
WO2011053614A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Crystalline cdm-nag and methods for producing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds

Also Published As

Publication number Publication date
EP0821691B1 (en) 2003-08-06
JPH11504348A (ja) 1999-04-20
US5756695A (en) 1998-05-26
EP0821691A4 (en) 2001-10-04
DE69723926T2 (de) 2004-07-15
JP3220704B2 (ja) 2001-10-22
AU1858697A (en) 1997-09-02
DE69723926D1 (de) 2003-09-11
AU712149B2 (en) 1999-10-28
WO1997030061A1 (en) 1997-08-21
JP2001316397A (ja) 2001-11-13
CA2217708A1 (en) 1997-08-21
EP0821691A1 (en) 1998-02-04

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties