DE69130955T2 - Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza) - Google Patents
Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza)Info
- Publication number
- DE69130955T2 DE69130955T2 DE69130955T DE69130955T DE69130955T2 DE 69130955 T2 DE69130955 T2 DE 69130955T2 DE 69130955 T DE69130955 T DE 69130955T DE 69130955 T DE69130955 T DE 69130955T DE 69130955 T2 DE69130955 T2 DE 69130955T2
- Authority
- DE
- Germany
- Prior art keywords
- influenzae
- prp
- adhesine
- proteins
- haemophilus influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/08—Polyoxyalkylene derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63169890A | 1990-12-21 | 1990-12-21 | |
PCT/US1991/009693 WO1992010936A1 (en) | 1990-12-21 | 1991-12-20 | ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR $i(HAEMOPHILUS INFLUENZAE) |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69130955D1 DE69130955D1 (de) | 1999-04-08 |
DE69130955T2 true DE69130955T2 (de) | 1999-07-01 |
Family
ID=24532360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69130955T Expired - Fee Related DE69130955T2 (de) | 1990-12-21 | 1991-12-20 | Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza) |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0565590B1 (de) |
JP (1) | JP3330935B2 (de) |
AT (1) | ATE176989T1 (de) |
CA (1) | CA2098598A1 (de) |
DE (1) | DE69130955T2 (de) |
DK (1) | DK0565590T3 (de) |
ES (1) | ES2131066T3 (de) |
WO (1) | WO1992010936A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0647139A4 (de) * | 1992-06-22 | 1997-09-03 | Microcarb Inc | KONJUGAT-IMPFSTOFF AUS ADHESIN-OLIGOSACCHARID GEGEN -i( HÄMOPHILUS IN FLUENZA). |
US5506139A (en) * | 1994-07-21 | 1996-04-09 | Connaught Laboratories Limited | Analog of haemophilus Hin47 with reduced protease activity |
US5981503A (en) * | 1994-06-07 | 1999-11-09 | Connaught Laboratories Limited | Analog of Haemophilus Hin47 with reduced protease activity |
US5939297A (en) * | 1994-07-21 | 1999-08-17 | Connaught Laboratories Limited | Analog of haemophilus HIN47 with reduced protease activity |
WO1996003506A2 (en) * | 1994-07-21 | 1996-02-08 | Connaught Laboratories Limited | Analog of haemophilus hin47 with reduced protease activity |
US6147057A (en) * | 1994-07-21 | 2000-11-14 | Connaught Laboratories Limited | Analog of Haemophilus Hin47 with reduced protease activity |
US5681570A (en) | 1995-01-12 | 1997-10-28 | Connaught Laboratories Limited | Immunogenic conjugate molecules |
US5646259A (en) * | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
US5780606A (en) * | 1995-06-07 | 1998-07-14 | Connaught Laboratories Limited | Neisseria meningitidis capsular polysaccharide conjugates |
US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
US6824997B1 (en) | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
JP4856836B2 (ja) * | 2000-03-01 | 2012-01-18 | バイナックス インコーポレイティッド | 標的細菌またはその標的糖質抗原成分の存在を検出する方法 |
CN109843899B (zh) | 2016-07-28 | 2022-04-19 | 马克斯·普朗克科学促进学会 | 用作对流感嗜血杆菌b型的疫苗的稳定耐水解的合成的聚核糖基核糖醇磷酸衍生物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
US5173294A (en) * | 1986-11-18 | 1992-12-22 | Research Foundation Of State University Of New York | Dna probe for the identification of haemophilus influenzae |
NZ223009A (en) * | 1986-12-31 | 1990-06-26 | Nl Rivm Of Thoven | Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens |
EP0320942A3 (de) * | 1987-12-18 | 1989-10-04 | American Cyanamid Company | Polysaccharide und makromolekulare Verbindungen davon |
ES2051909T3 (es) * | 1988-04-19 | 1994-07-01 | American Cyanamid Co | Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b. |
CA2006587C (en) * | 1988-12-23 | 2000-01-18 | Robert W. Tolan | Membrane proteins and peptides of haemophilus influenzae type b |
GB8924473D0 (en) * | 1989-10-31 | 1989-12-20 | Connaught Lab | Outer membrane protein p1 and peptides of haemophilus influenzae b |
-
1991
- 1991-12-20 ES ES92902826T patent/ES2131066T3/es not_active Expired - Lifetime
- 1991-12-20 DK DK92902826T patent/DK0565590T3/da active
- 1991-12-20 DE DE69130955T patent/DE69130955T2/de not_active Expired - Fee Related
- 1991-12-20 WO PCT/US1991/009693 patent/WO1992010936A1/en active IP Right Grant
- 1991-12-20 EP EP92902826A patent/EP0565590B1/de not_active Expired - Lifetime
- 1991-12-20 JP JP50297992A patent/JP3330935B2/ja not_active Expired - Fee Related
- 1991-12-20 CA CA002098598A patent/CA2098598A1/en not_active Abandoned
- 1991-12-20 AT AT92902826T patent/ATE176989T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1992010936A1 (en) | 1992-07-09 |
EP0565590B1 (de) | 1999-03-03 |
DK0565590T3 (da) | 1999-09-27 |
ATE176989T1 (de) | 1999-03-15 |
DE69130955D1 (de) | 1999-04-08 |
EP0565590A1 (de) | 1993-10-20 |
ES2131066T3 (es) | 1999-07-16 |
CA2098598A1 (en) | 1992-06-22 |
JP3330935B2 (ja) | 2002-10-07 |
JPH06508346A (ja) | 1994-09-22 |
EP0565590A4 (de) | 1995-07-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |