DE69719958T2 - Verfahren zur herstellung eines autologen fibrinklebers - Google Patents

Verfahren zur herstellung eines autologen fibrinklebers

Info

Publication number
DE69719958T2
DE69719958T2 DE69719958T DE69719958T DE69719958T2 DE 69719958 T2 DE69719958 T2 DE 69719958T2 DE 69719958 T DE69719958 T DE 69719958T DE 69719958 T DE69719958 T DE 69719958T DE 69719958 T2 DE69719958 T2 DE 69719958T2
Authority
DE
Germany
Prior art keywords
bag
centrifugation
plasma
fibrin glue
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69719958T
Other languages
English (en)
Other versions
DE69719958D1 (de
Inventor
Flavio Tarantino
Carlo Benincasa
Rocco Iannini
Walter Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CLAROL A G
Original Assignee
CLAROL A G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CLAROL A G filed Critical CLAROL A G
Application granted granted Critical
Publication of DE69719958D1 publication Critical patent/DE69719958D1/de
Publication of DE69719958T2 publication Critical patent/DE69719958T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0445—Proteins
    • A61M2202/0447—Glycoproteins
    • A61M2202/0449—Fibrinogen, also called factor 1

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69719958T 1996-09-18 1997-09-13 Verfahren zur herstellung eines autologen fibrinklebers Expired - Fee Related DE69719958T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001914A IT1284550B1 (it) 1996-09-18 1996-09-18 Procedimento per la preparazione di colla di fibrina autologa ad uso chirurgico
PCT/EP1997/005104 WO1998011925A1 (en) 1996-09-18 1997-09-13 Process of preparation of an autologous fibrin glue

Publications (2)

Publication Number Publication Date
DE69719958D1 DE69719958D1 (de) 2003-04-24
DE69719958T2 true DE69719958T2 (de) 2003-12-11

Family

ID=11374893

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719958T Expired - Fee Related DE69719958T2 (de) 1996-09-18 1997-09-13 Verfahren zur herstellung eines autologen fibrinklebers

Country Status (7)

Country Link
EP (1) EP0877632B1 (de)
AT (1) ATE234644T1 (de)
AU (1) AU4459697A (de)
DE (1) DE69719958T2 (de)
ES (1) ES2194219T3 (de)
IT (1) IT1284550B1 (de)
WO (1) WO1998011925A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US6274090B1 (en) * 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
ITAL990010U1 (it) 1999-12-14 2001-06-14 Maria Cristina Sacchi Nuova metodica di laboratorio per preparare gel e membrane piastriniche ottenute dal concentrato piastrinico.
EP1155706A1 (de) * 2000-05-19 2001-11-21 Xun Yang Huang Apparat zur Herstellung von Fibrinkleber und seine medizinische Anwendung
ES2524444T3 (es) * 2002-06-27 2014-12-09 Roberto Beretta Método para preparar una lámina de fibrina sólida
ITMI20021917A1 (it) * 2002-09-10 2004-03-11 New Dawn Consultores E Servicos L Da Attivatore per la formazione di gel piastrinico, gel di plasma povero di piastrine o gel di plasma ricco di piastrine.
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
ES2264353B1 (es) * 2004-10-26 2007-11-01 Instituto Oftalmologico De Alicante,S.L. Bioadhesivo bicomponente para uso biomedico.
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
ES2324438B1 (es) * 2006-06-19 2010-05-25 Lorente Alvarez-Beigbeder, S.L. Metodo para la obtencion de plaquetas.
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
US20100076465A1 (en) * 2007-05-15 2010-03-25 Axongen Ab Fibrin-based nerve repair conduit and method of producing the same
CL2011001870A1 (es) 2011-08-03 2012-01-27 U Tecnica Federico Santa Maria 28 71% Proceso de preparacion de un gel de fibrina autologo o desde sangre compatible para proliferacion y vehiculizacion celular; gel de fibrina o de sangre compatible; uso del gel de fibrina o de sangre compatible para uso quirurgico.
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
CN105307697A (zh) 2013-06-03 2016-02-03 皇冠医疗有限公司 自体纤维蛋白的临时制备
WO2014194930A1 (en) 2013-06-03 2014-12-11 Avance Medical Sàrl Extemporaneous preparation of autologous fibrin
CN104368052A (zh) * 2014-11-19 2015-02-25 绍兴市妇幼保健院 妊娠晚期贮存式自体成分输血系统的建立方法
IL281044B (en) * 2021-02-23 2022-04-01 Reddress Ltd Method and kit for treating an injured nerve

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
US4714457A (en) * 1986-09-15 1987-12-22 Robert Alterbaum Method and apparatus for use in preparation of fibrinogen from a patient's blood
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
WO1991016063A1 (en) * 1990-04-26 1991-10-31 Uab Research Foundation System for cryoprecipitating fibrinogen
IT1246530B (it) * 1991-03-29 1994-11-24 Miramed Spa Metodo e corredo pre-assemblato per l'ottenimento di colla di fibrina in ambiente completamente sterile.
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use

Also Published As

Publication number Publication date
IT1284550B1 (it) 1998-05-21
EP0877632B1 (de) 2003-03-19
ATE234644T1 (de) 2003-04-15
ITMI961914A1 (it) 1998-03-18
DE69719958D1 (de) 2003-04-24
AU4459697A (en) 1998-04-14
WO1998011925A1 (en) 1998-03-26
ES2194219T3 (es) 2003-11-16
EP0877632A1 (de) 1998-11-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee