DE69716505D1 - Implantatwerkstoff und Verfahren zu seiner Herstellung - Google Patents

Implantatwerkstoff und Verfahren zu seiner Herstellung

Info

Publication number
DE69716505D1
DE69716505D1 DE69716505T DE69716505T DE69716505D1 DE 69716505 D1 DE69716505 D1 DE 69716505D1 DE 69716505 T DE69716505 T DE 69716505T DE 69716505 T DE69716505 T DE 69716505T DE 69716505 D1 DE69716505 D1 DE 69716505D1
Authority
DE
Germany
Prior art keywords
implant
manufacture
surface treatment
implant material
nanotechnology process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69716505T
Other languages
English (en)
Other versions
DE69716505T2 (de
Inventor
Eugenia Ribeiro De Sous Leitao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OctoPlus Sciences BV
Original Assignee
Isotis NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isotis NV filed Critical Isotis NV
Application granted granted Critical
Publication of DE69716505D1 publication Critical patent/DE69716505D1/de
Publication of DE69716505T2 publication Critical patent/DE69716505T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • A61L27/06Titanium or titanium alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30906Special external or bone-contacting surface, e.g. coating for improving bone ingrowth shot- sand- or grit-blasted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00023Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00592Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/0097Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00976Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Cephalosporin Compounds (AREA)
DE69716505T 1996-05-10 1997-05-12 Implantatwerkstoff und Verfahren zu seiner Herstellung Expired - Fee Related DE69716505T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201293 1996-05-10

Publications (2)

Publication Number Publication Date
DE69716505D1 true DE69716505D1 (de) 2002-11-28
DE69716505T2 DE69716505T2 (de) 2003-06-26

Family

ID=8223977

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69720316T Expired - Fee Related DE69720316T2 (de) 1996-05-10 1997-05-12 Vorrichtung zur Aufnahme und Freigabe von biologisch aktiven Substanzen
DE69716505T Expired - Fee Related DE69716505T2 (de) 1996-05-10 1997-05-12 Implantatwerkstoff und Verfahren zu seiner Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69720316T Expired - Fee Related DE69720316T2 (de) 1996-05-10 1997-05-12 Vorrichtung zur Aufnahme und Freigabe von biologisch aktiven Substanzen

Country Status (5)

Country Link
US (2) US6069295A (de)
AT (2) ATE235927T1 (de)
CA (2) CA2205104A1 (de)
DE (2) DE69720316T2 (de)
ES (2) ES2185861T3 (de)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863201A (en) * 1994-11-30 1999-01-26 Implant Innovations, Inc. Infection-blocking dental implant
US6652765B1 (en) * 1994-11-30 2003-11-25 Implant Innovations, Inc. Implant surface preparation
AU4505196A (en) * 1994-11-30 1996-06-19 Implant Innovations, Inc. Implant surface preparation
US6491723B1 (en) * 1996-02-27 2002-12-10 Implant Innovations, Inc. Implant surface preparation method
AU736216B2 (en) * 1997-03-27 2001-07-26 Smith & Nephew, Inc. Method of surface oxidizing zirconium alloys and resulting product
SE9701647D0 (sv) * 1997-04-30 1997-04-30 Nobel Biocare Ab Calcium-phonsphate coated implant element
JP2000093503A (ja) 1998-09-15 2000-04-04 Isotis Bv 医療用インプラントをコ―トする方法
JP3072373B1 (ja) * 1999-07-05 2000-07-31 工業技術院長 汚濁物質、雑菌付着抑制機能および耐酸性を有する人工歯根ならびに製造方法
US20060194008A1 (en) * 1999-09-22 2006-08-31 Princeton University Devices with multiple surface functionality
US8012590B2 (en) 2000-05-01 2011-09-06 The Regents Of The University Of California Glass/ceramic coatings for implants
US6610067B2 (en) 2000-05-01 2003-08-26 Arthrosurface, Incorporated System and method for joint resurface repair
US6520964B2 (en) 2000-05-01 2003-02-18 Std Manufacturing, Inc. System and method for joint resurface repair
US6805898B1 (en) * 2000-09-28 2004-10-19 Advanced Cardiovascular Systems, Inc. Surface features of an implantable medical device
US7083642B2 (en) * 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
US6599322B1 (en) 2001-01-25 2003-07-29 Tecomet, Inc. Method for producing undercut micro recesses in a surface, a surgical implant made thereby, and method for fixing an implant to bone
US7018418B2 (en) * 2001-01-25 2006-03-28 Tecomet, Inc. Textured surface having undercut micro recesses in a surface
US6620332B2 (en) 2001-01-25 2003-09-16 Tecomet, Inc. Method for making a mesh-and-plate surgical implant
JP2002322013A (ja) * 2001-04-25 2002-11-08 Univ Nagoya 活性物質の前駆体、該前駆体を用いた活性物質、及びその活性物質の製造方法
US7695521B2 (en) 2001-05-01 2010-04-13 Amedica Corporation Hip prosthesis with monoblock ceramic acetabular cup
US7776085B2 (en) * 2001-05-01 2010-08-17 Amedica Corporation Knee prosthesis with ceramic tibial component
US20050177238A1 (en) * 2001-05-01 2005-08-11 Khandkar Ashok C. Radiolucent bone graft
AU2002324443A1 (en) * 2001-06-14 2003-01-02 Amedica Corporation Metal-ceramic composite articulation
SE519531C2 (sv) * 2001-07-04 2003-03-11 Nobel Biocare Ab Implantat innefattande porarrangemang belagt med kalciumfosfat
JP4347044B2 (ja) * 2001-07-26 2009-10-21 アバンテク バスキュラー コーポレーション 可変放出プロフィールを有する治療用薬剤を送達するための装置
DK1448246T4 (en) 2001-11-19 2015-12-21 Scil Technology Gmbh Homogeneously coated device with osteoinductive and osteoconductive properties
JP4595081B2 (ja) * 2002-02-26 2010-12-08 オステム インプラント コ.リミテッド リン酸カルシウムコロイド、ドット、アイランド、薄膜または、グラニュール、およびその調製
EP1358859A1 (de) * 2002-04-29 2003-11-05 Politecnico Di Milano Knochenprothesen mit mehrlagiger Oberfläche
GB0210786D0 (en) * 2002-05-10 2002-06-19 Plasma Coatings Ltd Orthopaedic and dental implants
US6794273B2 (en) * 2002-05-24 2004-09-21 Fujitsu Limited Semiconductor device and manufacturing method thereof
US20100185294A1 (en) * 2002-06-04 2010-07-22 Arthrosurface Incorporated Nanorough Alloy Substrate
SE523236C2 (sv) * 2002-07-19 2004-04-06 Astra Tech Ab Ett implantat och ett förfarande för behandling av en implantatyta
SE523288C2 (sv) * 2002-07-19 2004-04-06 Astra Tech Ab Ett implantat och ett förfarande för behandling av en implantatyta
CN100522241C (zh) 2002-09-10 2009-08-05 Scil技术股份有限公司 在低氧气浓度下用骨诱导蛋白包被的金属植入物
EP1572042A4 (de) * 2002-12-17 2010-12-08 Amedica Corp Zwischenwirbeltotalimplantat
GB0304168D0 (en) * 2003-02-24 2003-03-26 Benoist Girard Sas Surface treatment of metal
US20040167632A1 (en) * 2003-02-24 2004-08-26 Depuy Products, Inc. Metallic implants having roughened surfaces and methods for producing the same
US8388624B2 (en) 2003-02-24 2013-03-05 Arthrosurface Incorporated Trochlear resurfacing system and method
US8251700B2 (en) * 2003-05-16 2012-08-28 Biomet 3I, Llc Surface treatment process for implants made of titanium alloy
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US20040267376A1 (en) * 2003-06-25 2004-12-30 Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd) Ceramic member for medical implant and its production method
US7419680B2 (en) * 2003-10-01 2008-09-02 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
US9199005B2 (en) * 2003-10-01 2015-12-01 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
DE60329848D1 (de) * 2003-11-04 2009-12-10 Friadent Gmbh Dentalimplantatelement
EP1529498B9 (de) * 2003-11-05 2014-09-10 Dentsply Implants Manufacturing GmbH Mehrteiliges nichtmetallisches Implantat
WO2005074530A2 (en) * 2004-01-30 2005-08-18 Georgette Frederick S Metallic bone implant having improved implantability and method of making the same
JP2008504107A (ja) 2004-06-28 2008-02-14 アースロサーフィス・インコーポレーテッド 関節面交換用システム
SE530060C2 (sv) * 2004-09-01 2008-02-19 Nobel Biocare Ab Implantat för dental protetik och förfarande och system för framställning av implantatet
US7473278B2 (en) 2004-09-16 2009-01-06 Smith & Nephew, Inc. Method of surface oxidizing zirconium and zirconium alloys and resulting product
US8750983B2 (en) 2004-09-20 2014-06-10 P Tech, Llc Therapeutic system
US7785648B2 (en) * 2004-09-22 2010-08-31 New York University Adherent apatite coating on titanium substrate using chemical deposition
US7235592B2 (en) * 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
US7879388B2 (en) * 2004-10-28 2011-02-01 The Regents Of The University Of Michigan Methods for production and use of synthetic hydroxyapatite and fluorapatite nanorods, and superstructures assembled from the same
CA2532388A1 (en) * 2005-01-07 2006-07-07 Inframat Corporation Coated medical devices and methods of making and using
WO2006091706A1 (en) 2005-02-23 2006-08-31 Zimmer Technology, Inc. Blend hydrogels and methods of making
WO2006091582A2 (en) * 2005-02-24 2006-08-31 Implant Innovations, Inc. Surface treatment methods for implants made of titanium or titanium alloy
JP2008538718A (ja) * 2005-04-22 2008-11-06 ハイブリッド・プラスティックス・インコーポレイテッド ポリヘドラルオリゴメリックシルセスキオキサンを含むバイオミメチック材料
US7901462B2 (en) * 2005-06-23 2011-03-08 Depuy Products, Inc. Implants with textured surface and methods for producing the same
US7571295B2 (en) * 2005-08-04 2009-08-04 Intel Corporation Memory manager for heterogeneous memory control
US20070098799A1 (en) * 2005-10-28 2007-05-03 Zimmer, Inc. Mineralized Hydrogels and Methods of Making and Using Hydrogels
AU2006315629B2 (en) 2005-11-14 2012-04-19 Biomet 3I, Llc Deposition of discrete nanoparticles on an implant surface
AU2006321809A1 (en) * 2005-12-07 2007-06-14 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
WO2007078427A2 (en) * 2005-12-15 2007-07-12 Smith & Nephew, Inc. Diffusion-hardened medical implant
US20070141108A1 (en) * 2005-12-20 2007-06-21 Zimmer, Inc. Fiber-reinforced water-swellable articles
JP2007177244A (ja) * 2005-12-22 2007-07-12 Zimmer Inc ペルフルオロシクロブタン架橋ハイドロゲル
US8252058B2 (en) * 2006-02-16 2012-08-28 Amedica Corporation Spinal implant with elliptical articulatory interface
US20070198093A1 (en) * 2006-02-17 2007-08-23 Amedica Corporation Spinal implant with offset keels
US8110242B2 (en) * 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
EP1847278A1 (de) * 2006-04-13 2007-10-24 Camlog Biotechnologies AG Bio-auflösende Salzbeschichtungen von Implantaten zum Schutz vor organischen Verunreinigungen
US20110213375A1 (en) 2006-07-17 2011-09-01 Arthrosurface, Inc. Tibial Resurfacing System and Method
US20080069854A1 (en) * 2006-08-02 2008-03-20 Inframat Corporation Medical devices and methods of making and using
US20080124373A1 (en) * 2006-08-02 2008-05-29 Inframat Corporation Lumen - supporting devices and methods of making and using
NO20064595A (no) * 2006-10-10 2008-03-17 Roella Gunnar Titanimplantat og fremgangsmåte for fremstilling derav
EP2079401B1 (de) 2006-10-24 2019-05-22 Biomet 3i, LLC Ablagerung diskreter nanopartikel auf einer nanostrukturierten oberfläche eines implantats
AU2007332787A1 (en) 2006-12-11 2008-06-19 Arthrosurface Incorporated Retrograde resection apparatus and method
KR100930279B1 (ko) * 2007-06-20 2009-12-09 재단법인서울대학교산학협력재단 인산칼슘 극초박막 및 그의 제조법
US20090008365A1 (en) * 2007-07-06 2009-01-08 Depuy Products, Inc. Microtextured Implants and Methods of Making Same
EP2022447A1 (de) * 2007-07-09 2009-02-11 Astra Tech AB Nanooberfläche
KR100775537B1 (ko) * 2007-07-19 2007-11-28 (주)오스테오필 표면이 개질된 임플란트 제조 방법 및 그에 의해 제조된임플란트
US20090187197A1 (en) * 2007-08-03 2009-07-23 Roeber Peter J Knit PTFE Articles and Mesh
US20090036996A1 (en) * 2007-08-03 2009-02-05 Roeber Peter J Knit PTFE Articles and Mesh
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US7947784B2 (en) * 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
US8034362B2 (en) 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
ES2545781T3 (es) 2008-01-28 2015-09-15 Biomet 3I, Llc Implante superficial con mayor hidrofilia
US8361381B2 (en) 2008-09-25 2013-01-29 Smith & Nephew, Inc. Medical implants having a porous coated surface
US9592043B2 (en) * 2009-03-31 2017-03-14 Covidien Lp Multizone implants
US8696759B2 (en) * 2009-04-15 2014-04-15 DePuy Synthes Products, LLC Methods and devices for implants with calcium phosphate
US20100268227A1 (en) * 2009-04-15 2010-10-21 Depuy Products, Inc. Methods and Devices for Bone Attachment
EP2429429B1 (de) 2009-04-17 2018-07-25 Arthrosurface Incorporated Schultergelenk-oberflächenersatzsystem
US10945743B2 (en) 2009-04-17 2021-03-16 Arthrosurface Incorporated Glenoid repair system and methods of use thereof
WO2010121250A1 (en) 2009-04-17 2010-10-21 Arthrosurface Incorporated Glenoid resurfacing system and method
US8475536B2 (en) * 2010-01-29 2013-07-02 DePuy Synthes Products, LLC Methods and devices for implants with improved cement adhesion
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
TWI543754B (zh) * 2010-06-24 2016-08-01 Univ Kaohsiung Medical Surface treatment of dental implants with tissue integration
DE102010025533B4 (de) * 2010-06-29 2014-09-04 Heraeus Medical Gmbh Verfahren zur knochenwachstumsfördernden Beschichtung
US9381112B1 (en) 2011-10-06 2016-07-05 William Eric Sponsell Bleb drainage device, ophthalmological product and methods
US8632489B1 (en) 2011-12-22 2014-01-21 A. Mateen Ahmed Implantable medical assembly and methods
WO2013096746A1 (en) 2011-12-22 2013-06-27 Arthrosurface Incorporated System and method for bone fixation
WO2013142118A1 (en) 2012-03-20 2013-09-26 Biomet 3I, Llc Surface treatment for an implant surface
WO2014008126A1 (en) 2012-07-03 2014-01-09 Arthrosurface Incorporated System and method for joint resurfacing and repair
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US9931219B2 (en) 2014-03-07 2018-04-03 Arthrosurface Incorporated Implant and anchor assembly
US10842634B2 (en) * 2014-05-02 2020-11-24 The Royal Institution For The Advancement Of Learning/Mcgill University Structural porous biomaterial and implant formed of same
WO2015200266A1 (en) * 2014-06-23 2015-12-30 Community Blood Center Cellular-scale surface modification for increased osteogenic protein expression
CN108096640A (zh) * 2016-11-24 2018-06-01 重庆润泽医药有限公司 一种多孔材料
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
WO2019028344A1 (en) 2017-08-04 2019-02-07 Arthrosurface Incorporated JOINT SURFACE IMPLANT WITH MULTIPLE COMPONENTS
US11478358B2 (en) 2019-03-12 2022-10-25 Arthrosurface Incorporated Humeral and glenoid articular surface implant systems and methods

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984914A (en) * 1974-07-24 1976-10-12 Robert Schwartz Oral implant
JPS5214095A (en) * 1975-07-23 1977-02-02 Sumitomo Chemical Co Implant in bone
US4687487A (en) * 1978-07-21 1987-08-18 Association Suisse Pour La Recherches Horlogere Joint implant
SE416175B (sv) * 1979-03-07 1980-12-08 Per Ingvar Branemark For implantering i kroppsvevnad serskilt benvevnad, avsett material
DE3223925C2 (de) * 1982-06-26 1986-07-31 Feldmühle AG, 4000 Düsseldorf Implantierbares Ellbogengelenk
GB8318483D0 (en) * 1983-07-08 1983-08-10 Zimmer Deloro Surgical Ltd Skeletal implants
US4636526A (en) * 1985-02-19 1987-01-13 The Dow Chemical Company Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics
FR2585576B1 (fr) * 1985-07-30 1992-01-03 Bioetica Sa Produit de remplacement de la matrice osseuse favorisant l'osteogenese
US4818559A (en) * 1985-08-08 1989-04-04 Sumitomo Chemical Company, Limited Method for producing endosseous implants
JPH0669482B2 (ja) * 1985-08-08 1994-09-07 住友化学工業株式会社 骨内インプラントの製造法
DD246028A1 (de) * 1986-02-12 1987-05-27 Karl Marx Stadt Tech Hochschul Keramisiertes metallimplantat
GB2189815B (en) * 1986-03-24 1990-10-10 Permelec Electrode Ltd Titanium composite materials coated with calcium phosphate compound and process for production thereof
US5344457A (en) * 1986-05-19 1994-09-06 The University Of Toronto Innovations Foundation Porous surfaced implant
JPS6399867A (ja) * 1986-10-17 1988-05-02 ペルメレツク電極株式会社 リン酸カルシウム化合物被覆複合材及びその製造方法
US4879136A (en) * 1987-02-24 1989-11-07 Dentsply G.M.B.H. Method of applying opaque dental ceramic material to a metal structure
JPS6486975A (en) * 1987-09-29 1989-03-31 Permelec Electrode Ltd Preparation of calcium phosphate compound coated composite material
DE3865421D1 (de) * 1987-12-23 1991-11-14 Sumitomo Chemical Co Hydroxyapatit enthaltende beschichtungsfluessigkeit und verfahren zur herstellung eines hydroxyapatitueberzugs unter verwendung derselben.
US5180426A (en) * 1987-12-28 1993-01-19 Asahi Kogaku Kogyo K.K. Composition for forming calcium phosphate type setting material and process for producing setting material
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
US5219361A (en) * 1988-09-16 1993-06-15 Clemson University Soft tissue implant with micron-scale surface texture to optimize anchorage
ES2044211T3 (es) * 1989-03-23 1994-01-01 Straumann Inst Ag Implante metalico.
JP2830262B2 (ja) * 1990-01-08 1998-12-02 住友化学工業株式会社 ハイドロキシアパタイト皮膜の形成方法
US5164187A (en) * 1990-04-05 1992-11-17 Norian Corporation Hydroxyapatite prosthesis coatings
JP2978203B2 (ja) * 1990-04-20 1999-11-15 日本特殊陶業株式会社 生体活性な表面層を有するセラミックス体の製造方法
SE468153B (sv) * 1990-10-08 1992-11-16 Astra Meditec Ab Saett foer ytbehandling av implantat av titan eller titanlegering
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US5478237A (en) * 1992-02-14 1995-12-26 Nikon Corporation Implant and method of making the same
US5358529A (en) * 1993-03-05 1994-10-25 Smith & Nephew Richards Inc. Plastic knee femoral implants
NL9301941A (nl) * 1993-11-09 1995-06-01 Klaas De Groot Werkwijze voor het aanbrengen van een bekleding van een bioactief materiaal op implantaten.
US5607480A (en) * 1993-11-10 1997-03-04 Implant Innovations, Inc. Surgically implantable prosthetic devices
US5947893A (en) * 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
AU4505196A (en) * 1994-11-30 1996-06-19 Implant Innovations, Inc. Implant surface preparation
AU723740B2 (en) * 1995-06-06 2000-09-07 Howmedica Inc. Biocompatible hydroxyapatite formulations and uses therefor
JPH0956805A (ja) * 1995-08-24 1997-03-04 Millennium Biologics Inc リン酸カルシウム材の薄膜製造のための改良焼結方法
US5730598A (en) * 1997-03-07 1998-03-24 Sulzer Calcitek Inc. Prosthetic implants coated with hydroxylapatite and process for treating prosthetic implants plasma-sprayed with hydroxylapatite

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US6069295A (en) 2000-05-30
DE69716505T2 (de) 2003-06-26
ATE226453T1 (de) 2002-11-15
ES2196252T3 (es) 2003-12-16
US6146686A (en) 2000-11-14
ATE235927T1 (de) 2003-04-15
CA2205107A1 (en) 1997-11-10
ES2185861T3 (es) 2003-05-01
CA2205104A1 (en) 1997-11-10
DE69720316T2 (de) 2004-04-01

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