DE69636951D1 - Pharmazeutisch aktive karotenoide - Google Patents

Pharmazeutisch aktive karotenoide

Info

Publication number
DE69636951D1
DE69636951D1 DE69636951T DE69636951T DE69636951D1 DE 69636951 D1 DE69636951 D1 DE 69636951D1 DE 69636951 T DE69636951 T DE 69636951T DE 69636951 T DE69636951 T DE 69636951T DE 69636951 D1 DE69636951 D1 DE 69636951D1
Authority
DE
Germany
Prior art keywords
carotenoids
pharmaceutically active
zeaxanthin
lutein
active carotenoids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69636951T
Other languages
English (en)
Other versions
DE69636951T2 (de
Inventor
Alan Norman White Howard
Miami Landrum
Miami Bone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOWARD FOUNDATION CAMBRIDGE
Howard Foundation
Original Assignee
HOWARD FOUNDATION CAMBRIDGE
Howard Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9604221.3A external-priority patent/GB9604221D0/en
Application filed by HOWARD FOUNDATION CAMBRIDGE, Howard Foundation filed Critical HOWARD FOUNDATION CAMBRIDGE
Application granted granted Critical
Publication of DE69636951D1 publication Critical patent/DE69636951D1/de
Publication of DE69636951T2 publication Critical patent/DE69636951T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • A23L33/155Vitamins A or D
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69636951T 1995-06-07 1996-06-07 Pharmazeutisch aktive karotenoide Expired - Lifetime DE69636951T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48762795A 1995-06-07 1995-06-07
US487627 1995-06-07
GB9604221 1996-02-28
GBGB9604221.3A GB9604221D0 (en) 1995-06-07 1996-02-28 Pharmaceutically active carotenoids
PCT/GB1996/001368 WO1996040092A1 (en) 1995-06-07 1996-06-07 Pharmaceutically active carotenoids

Publications (2)

Publication Number Publication Date
DE69636951D1 true DE69636951D1 (de) 2007-04-19
DE69636951T2 DE69636951T2 (de) 2007-11-22

Family

ID=26308821

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69636951T Expired - Lifetime DE69636951T2 (de) 1995-06-07 1996-06-07 Pharmazeutisch aktive karotenoide

Country Status (10)

Country Link
EP (1) EP0831797B1 (de)
AT (1) ATE355832T1 (de)
AU (1) AU719671B2 (de)
CA (1) CA2224217C (de)
DE (1) DE69636951T2 (de)
DK (1) DK0831797T3 (de)
ES (1) ES2283002T3 (de)
GB (1) GB2301775B (de)
NZ (1) NZ309130A (de)
WO (1) WO1996040092A1 (de)

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CA2188983C (en) * 1995-10-31 2001-02-27 Kevin M. Garnett Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans
US5747544A (en) * 1995-10-31 1998-05-05 Applied Food Biotechnology, Inc. Method of using pure 3R-3'R stereoisomer of zeaxanthin to treat or prevent retinal degeneration in humans
US5827652A (en) 1995-10-31 1998-10-27 Applied Food Biotechnology, Inc. Zeaxanthin formulations for human ingestion
WO1997048388A1 (en) * 1996-06-17 1997-12-24 The Board Of Trustees Of The University Of Illinois Method of retarding and ameliorating central nervous system and eye damage
GB9704972D0 (en) * 1997-03-11 1997-04-30 Howard Foundation Flicker photometer
WO1999018814A1 (en) * 1997-10-14 1999-04-22 Quest International B.V. Preparation for the enhancement of the antioxidant status of cells
WO1999047001A1 (en) * 1998-03-18 1999-09-23 Kemin Industries, Inc. Increased bioavailability of lutein and zeaxanthin in humans and poultry using lysolecithin and lecithin
US6191293B1 (en) 1998-04-20 2001-02-20 Inexa, Industria Extractora C.A. Trans-xanthophyll ester concentrates of enhanced purity and methods of making same
NL1010351C2 (nl) * 1998-10-19 2001-01-08 Werklust & Beheer B V Esters van caroteno´den voor gebruik in de preventie en behandeling van oogaandoeningen.
IT1307281B1 (it) * 1999-11-25 2001-10-30 Simonelli Giuseppe Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,
US7691406B2 (en) 2000-10-27 2010-04-06 ZeaVision LLC. Zeaxanthin formulations for human ingestion
DE10112067A1 (de) 2001-03-12 2002-09-19 Basf Ag Verfahren zur Herstellung von 2,7-Dimethyl-2,4,6-octarienal-monoacetalen
US6660297B2 (en) 2001-03-23 2003-12-09 Bausch & Lomb Incorporated Nutritional supplement to treat macular degeneration
JP2004532831A (ja) * 2001-03-27 2004-10-28 シー.エス. バイオサイエンス、 インコーポレイテッド 歯科用調剤
US7575766B2 (en) 2001-06-29 2009-08-18 Ball Horticultural Company Tagetes erecta with altered carotenoid compositions and ratios
US7081478B2 (en) 2001-06-29 2006-07-25 Chrysantis, Inc. Mixed zeaxanthin ester concentrate and uses thereof
US6784351B2 (en) 2001-06-29 2004-08-31 Ball Horticultural Company Targetes erecta marigolds with altered carotenoid compositions and ratios
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
CN1625395A (zh) * 2002-01-30 2005-06-08 Dsmip资产公司 叶黄素/玉米黄质用于眩光保护
CN1649574A (zh) * 2002-02-15 2005-08-03 Dsmip资产公司 用于治疗和预防血管发生相关性病变的包含蕃茄红素的组合物
US7223909B2 (en) 2002-03-21 2007-05-29 Ball Horticultural 4-ketocarotenoids in flower petals
US20030228392A1 (en) * 2002-06-06 2003-12-11 Wyeth Infant formula compositions containing lutein and zeaxanthin
EP1864654A1 (de) * 2002-06-06 2007-12-12 Wyeth a Corporation of the State of Delaware Säuglingsnahrungszusammensetzungen mit Lutein und Zeaxanthin
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
US9192586B2 (en) 2003-03-10 2015-11-24 Zeavision Llc Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
DE20300305U1 (de) 2003-01-09 2003-04-24 Mann Gerhard Chem Pharm Fab Ocuvite Lutein
DE20300304U1 (de) * 2003-01-09 2003-04-24 Mann Gerhard Chem Pharm Fab Ocuvite Zink
US7941211B2 (en) 2003-11-17 2011-05-10 Zeavision, Llc. Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders
DE20320101U1 (de) 2003-12-23 2004-04-29 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Mikronährstoffkombinationsprodukt geeignet zur ergänzenden bilanzierten Diät bei altersbedingter Makuladegeneration
US7351424B2 (en) 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
EP1814540A2 (de) * 2004-11-16 2007-08-08 Nu-Tein Co., Inc. Zusammensetzungen zur behandlung von neovaskulären augenerkrankungen und maculadegeneration
EP2329815A1 (de) * 2005-02-11 2011-06-08 Kalamazoo Holdings, Inc. Capsicum Varietät, welche eine Hyperakkumulation von Zeaxanthin aufweist und daraus abgeleitete Produkte
US8592662B2 (en) 2005-02-11 2013-11-26 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
WO2006102576A1 (en) * 2005-03-23 2006-09-28 Cardax Pharmaceuticals, Inc. Water-dispersible carotenoids, including analogs and derivatives
US20090155381A1 (en) * 2005-09-08 2009-06-18 Regina Goralczyc Method of treatment or prevention of age-related macular degeneration
EP1920711A1 (de) * 2006-11-13 2008-05-14 DSMIP Assets B.V. Beurteilung und Verbesserung der Sehfähigkeit
US8063101B2 (en) 2007-03-23 2011-11-22 Cardax Pharmaceuticals, Inc. Carotenoid analogs and derivatives for the prevention of platelet aggregation
PT2473065E (pt) 2009-09-02 2016-06-03 Omniactive Health Tech Ltd Uma composição de xantofila contendo pigmentos maculares e um processo para a sua preparação
WO2011076869A1 (en) * 2009-12-22 2011-06-30 Aakerlund Hans-Erik Isolated green plant material
MX349133B (es) * 2011-07-07 2017-07-13 Howard Found Holdings Ltd Mejoras en o con relacion al desempeño visual y/o pigmentacion macular.
ES2754279T3 (es) * 2011-07-13 2020-04-16 Univ Georgia Uso de carotenoides de xantofila para mejorar el rendimiento visual y la eficiencia neuronal
DE102017009186A1 (de) 2017-09-25 2019-03-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lutein und -derivate enthaltende Zusammensetzung sowie Verfahren zur Herstellung
EP4254344A1 (de) 2022-03-31 2023-10-04 Imagination Technologies Limited Parallele optimierung von begrenzungsvolumenhierarchie

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DK0534955T3 (da) * 1989-08-30 1997-10-13 Applied Food Biotech Inc Fremgangsmåde til fremstilling af en zeaxanthinholdig sammensætning under anvendelse af en mikroorganisme af arten Flavobacterium multivorum.
GB9105420D0 (en) * 1991-03-14 1991-05-01 Ici Plc Expression of genes in transgenic plants
JPH05163143A (ja) * 1991-12-16 1993-06-29 Nisshin Flour Milling Co Ltd α−トコフェロールビタミンA酸エステル含有油性組成物
US5310764A (en) * 1992-05-08 1994-05-10 Steven Baranowitz Treatment of age related macular degeneration with beta-carotene
JPH05320036A (ja) * 1992-05-19 1993-12-03 Shiseido Co Ltd 一重項酸素除去組成物
JPH0665033A (ja) * 1992-08-11 1994-03-08 Lion Corp 口腔用組成物
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GB2274235B (en) * 1993-01-13 1996-06-26 Neo Life Company Of America Carotenoid food supplement
IL110139A0 (en) * 1993-06-28 1994-10-07 Howard Foundation Pharmaceutically-active antioxidants
US5382714A (en) * 1994-03-17 1995-01-17 The Catholic University Of America Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof
EP0793490A4 (de) * 1994-12-22 1999-12-15 Henkel Corp Zusammensetzungen aus tocopherol und beta-karotin
ATE201380T1 (de) * 1995-03-10 2001-06-15 Inventio Ag Einrichtung und verfahren zur schwingungsdämpfung an einer aufzugskabine

Also Published As

Publication number Publication date
EP0831797A1 (de) 1998-04-01
NZ309130A (en) 2001-06-29
WO1996040092A1 (en) 1996-12-19
DE69636951T2 (de) 2007-11-22
ATE355832T1 (de) 2007-03-15
CA2224217C (en) 2010-04-13
GB2301775A (en) 1996-12-18
AU719671B2 (en) 2000-05-18
CA2224217A1 (en) 1996-12-19
GB2301775B (en) 1999-08-04
GB9611967D0 (en) 1996-08-07
EP0831797B1 (de) 2007-03-07
DK0831797T3 (da) 2007-04-02
AU5907896A (en) 1996-12-30
ES2283002T3 (es) 2007-10-16

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