WO2002041897A3 - Compositions pharmaceutiques a action antidiabetique constitues de l'association d'un biguanide et d'un sulfonamide - Google Patents

Compositions pharmaceutiques a action antidiabetique constitues de l'association d'un biguanide et d'un sulfonamide Download PDF

Info

Publication number
WO2002041897A3
WO2002041897A3 PCT/FR2001/003697 FR0103697W WO0241897A3 WO 2002041897 A3 WO2002041897 A3 WO 2002041897A3 FR 0103697 W FR0103697 W FR 0103697W WO 0241897 A3 WO0241897 A3 WO 0241897A3
Authority
WO
WIPO (PCT)
Prior art keywords
diabetic
pharmaceutical compositions
medicines
preparing same
novel pharmaceutical
Prior art date
Application number
PCT/FR2001/003697
Other languages
English (en)
Other versions
WO2002041897A2 (fr
Inventor
Nathalie Cugnardey
Nicolas Wiernsperger
Original Assignee
Lipha
Nathalie Cugnardey
Nicolas Wiernsperger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha, Nathalie Cugnardey, Nicolas Wiernsperger filed Critical Lipha
Priority to AU2002222026A priority Critical patent/AU2002222026A1/en
Publication of WO2002041897A2 publication Critical patent/WO2002041897A2/fr
Publication of WO2002041897A3 publication Critical patent/WO2002041897A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention se rapporte au domaine de la chimie thérapeutique et plus particulièrement à la réalisation de nouveaux médicaments pour le traitement du diabète. Elle a spécifiquement pour objet de nouveaux médicaments antidiabétiques constitués d'une association de deux principes actifs efficaces par voie orale, à doses subliminaires, formés d'un biguanide antidiabétique et d'un sulfonamide antidiabétique, en association ou en mélange avec un ou plusieurs excipients inertes, pharmaceutiquement acceptables. L'invention se rapporte en outre à un procédé de réalisation de tels médicaments formés d'un biguanide et d'un sulfonamide.
PCT/FR2001/003697 2000-11-22 2001-11-22 Compositions pharmaceutiques a action antidiabetique constitues de l'association d'un biguanide et d'un sulfonamide WO2002041897A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002222026A AU2002222026A1 (en) 2000-11-22 2001-11-22 Novel pharmaceutical compositions with anti-diabetic activity and method for preparing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015066A FR2816841B1 (fr) 2000-11-22 2000-11-22 Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
FR00/15066 2000-11-22

Publications (2)

Publication Number Publication Date
WO2002041897A2 WO2002041897A2 (fr) 2002-05-30
WO2002041897A3 true WO2002041897A3 (fr) 2003-05-30

Family

ID=8856750

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2001/012492 WO2002041879A2 (fr) 2000-11-22 2001-10-29 Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
PCT/FR2001/003697 WO2002041897A2 (fr) 2000-11-22 2001-11-22 Compositions pharmaceutiques a action antidiabetique constitues de l'association d'un biguanide et d'un sulfonamide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012492 WO2002041879A2 (fr) 2000-11-22 2001-10-29 Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation

Country Status (18)

Country Link
US (1) US20040039031A1 (fr)
EP (1) EP1335731A2 (fr)
JP (1) JP2004513962A (fr)
KR (1) KR20030051858A (fr)
CN (1) CN1474696A (fr)
AU (2) AU2002221779A1 (fr)
BR (1) BR0115506A (fr)
CA (1) CA2429257A1 (fr)
CZ (1) CZ20031449A3 (fr)
FR (1) FR2816841B1 (fr)
HU (1) HUP0302620A3 (fr)
MX (1) MXPA03004431A (fr)
NO (1) NO20032287L (fr)
PL (1) PL361189A1 (fr)
RU (1) RU2003116890A (fr)
SK (1) SK6452003A3 (fr)
WO (2) WO2002041879A2 (fr)
ZA (1) ZA200304766B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105809A1 (fr) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Comprimes multicouche contenant des thiazolidinediones et des biguanides et procedes de production desdits comprimes
JPWO2005117855A1 (ja) * 2004-06-04 2008-04-03 興和株式会社 糖尿病の予防または治療のための薬剤
WO2007105730A1 (fr) * 2006-03-13 2007-09-20 Kyowa Hakko Kogyo Co., Ltd. Agent ameliorant l'insulinoresistance
NZ579229A (en) * 2007-01-25 2011-07-29 Verva Pharmaceuticals Ltd Insulin sensitisers and methods of treatment
WO2009124386A1 (fr) * 2008-04-07 2009-10-15 Interface Biologics Inc. Polythérapie pour le traitement des infections bactériennes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2244481A1 (en) * 1973-09-21 1975-04-18 Hoechst Ag Oral treatment of diabetes - with a complex of glibenclamide and phenformin
WO1997017975A1 (fr) * 1995-11-14 1997-05-22 Abiogen Pharma S.R.L. Combinaison de glibenclamide et de metformine destinee au traitement du diabete sucre de type ii
WO1999029314A1 (fr) * 1997-12-08 1999-06-17 Bristol-Myers Squibb Company Sels de metformine et procede
EP0974356A1 (fr) * 1998-07-15 2000-01-26 Lipha Comprimés contenant une combinaison de glibenclamide et de metformine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2244481A1 (en) * 1973-09-21 1975-04-18 Hoechst Ag Oral treatment of diabetes - with a complex of glibenclamide and phenformin
WO1997017975A1 (fr) * 1995-11-14 1997-05-22 Abiogen Pharma S.R.L. Combinaison de glibenclamide et de metformine destinee au traitement du diabete sucre de type ii
WO1999029314A1 (fr) * 1997-12-08 1999-06-17 Bristol-Myers Squibb Company Sels de metformine et procede
EP0974356A1 (fr) * 1998-07-15 2000-01-26 Lipha Comprimés contenant une combinaison de glibenclamide et de metformine

Also Published As

Publication number Publication date
AU2002221779A1 (en) 2002-06-03
FR2816841B1 (fr) 2004-02-06
HUP0302620A3 (en) 2005-06-28
EP1335731A2 (fr) 2003-08-20
PL361189A1 (en) 2004-09-20
AU2002222026A1 (en) 2002-06-03
NO20032287D0 (no) 2003-05-21
WO2002041897A2 (fr) 2002-05-30
MXPA03004431A (es) 2003-08-19
SK6452003A3 (en) 2003-09-11
CN1474696A (zh) 2004-02-11
US20040039031A1 (en) 2004-02-26
BR0115506A (pt) 2003-10-21
HUP0302620A2 (hu) 2003-11-28
WO2002041879A2 (fr) 2002-05-30
RU2003116890A (ru) 2004-12-10
KR20030051858A (ko) 2003-06-25
NO20032287L (no) 2003-05-21
JP2004513962A (ja) 2004-05-13
ZA200304766B (en) 2004-09-20
FR2816841A1 (fr) 2002-05-24
CA2429257A1 (fr) 2002-05-30
WO2002041879A3 (fr) 2003-05-22
CZ20031449A3 (cs) 2003-09-17

Similar Documents

Publication Publication Date Title
EP1283054A4 (fr) Medicaments permettant de traiter les complications du diabete et des neuropathies et utilisation de ces medicaments
CA2386690A1 (fr) Sels pharmaceutiques de tramadol
WO2003039632A3 (fr) Recipient pour medicament, dispositif de distribution d'un medicament et procede de conditionnement
MXPA03007712A (es) Sales farmaceuticas.
IL147220A0 (en) Indanyl-substituted benzole carbonamide, method for the production of the same, use thereof as a medicament and pharmaceutical preparations containing the same
PL341466A1 (en) Instantaneously spreading dised pharmacological preparation and method of forming granules
CA2431565A1 (fr) Nouvelles compositions pharmaceutiques a base d'anticholinergiques et de ciclesonide
HUP0402154A2 (hu) Metformint és glibenklamidot tartalmazó gyógyászati készítmény II-es típusú diabetes mellitus kezelésére
WO2003035051A3 (fr) Utilisation d'agents sequestrants des protons dans des formulations medicamenteuses
HK1067626A1 (en) Novel 2h-pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient
WO2001041742A3 (fr) Medication antivirale
WO2002045686A3 (fr) Preparation pharmaceutique en pate comprenant un ingredient actif labile en milieu acide
CA2445519A1 (fr) Procede permettant de preparer une composition pharmaceutique faiblement dosee, a repartition et a activite uniformes du medicament
WO2003075829A3 (fr) Complexes a dissolution rapide, directement compressibles et insipides et preparations pharmaceutiques a base de ces complexes
IL150528A0 (en) Ibuprofen containing active agent preparation
ATE327737T1 (de) Verfahren zur herstellung von arzneistoffgranulatkörnern, die arzneistoffgranulatkörner sowie diese enthaltende pharmazeutische zubereitungen
ZA200208761B (en) Pharmaceutical form of administration for peptides, methods for its production and use.
WO2000008007A3 (fr) Derives de cyclopentabenzofuranne et leur utilisation
AU2001234107A1 (en) Benzoic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
WO2002053090A3 (fr) Association medicamenteuse d'une biguanine (metformine) et d'arginine
CA2350659A1 (fr) Composition pharmaceutique de sensibilisateur modifiant la liberation d'insuline
WO2002041897A3 (fr) Compositions pharmaceutiques a action antidiabetique constitues de l'association d'un biguanide et d'un sulfonamide
WO2003018535A3 (fr) Nouvelles aminobenzophenones
WO1999018941A3 (fr) MODULATEURS DE CANAL I¿h?
HUP0600084A2 (en) Pharmaceutical compositions containing ascorbic acid derivatives, methods of production of the active ingredient

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AU BA BG BR CA CN CO CZ DZ EE HR HU ID IL IN JP KP KR LT LV MA MD MG MK MX NO NZ PL RO RU SG SI SK UA US VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP