IL90794A - Nutritional sun-exposure supporting composition - Google Patents
Nutritional sun-exposure supporting compositionInfo
- Publication number
- IL90794A IL90794A IL9079489A IL9079489A IL90794A IL 90794 A IL90794 A IL 90794A IL 9079489 A IL9079489 A IL 9079489A IL 9079489 A IL9079489 A IL 9079489A IL 90794 A IL90794 A IL 90794A
- Authority
- IL
- Israel
- Prior art keywords
- composition
- group
- antioxidant
- physiologically
- carotenoids
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 39
- 235000016709 nutrition Nutrition 0.000 title description 5
- 230000036561 sun exposure Effects 0.000 title description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 36
- 235000021466 carotenoid Nutrition 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- 150000001747 carotenoids Chemical class 0.000 claims description 24
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 14
- 239000003963 antioxidant agent Substances 0.000 claims description 11
- 235000006708 antioxidants Nutrition 0.000 claims description 11
- 235000013734 beta-carotene Nutrition 0.000 claims description 11
- 239000011648 beta-carotene Substances 0.000 claims description 11
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims description 10
- 235000005979 Citrus limon Nutrition 0.000 claims description 9
- 244000131522 Citrus pyriformis Species 0.000 claims description 9
- 240000009088 Fragaria x ananassa Species 0.000 claims description 7
- 229960005070 ascorbic acid Drugs 0.000 claims description 7
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims description 7
- 240000007651 Rubus glaucus Species 0.000 claims description 6
- 239000011732 tocopherol Substances 0.000 claims description 6
- 244000246386 Mentha pulegium Species 0.000 claims description 5
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 5
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 5
- 235000010323 ascorbic acid Nutrition 0.000 claims description 5
- 239000011668 ascorbic acid Substances 0.000 claims description 5
- 150000001746 carotenes Chemical class 0.000 claims description 5
- 235000005473 carotenes Nutrition 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 235000001050 hortel pimenta Nutrition 0.000 claims description 5
- 235000013336 milk Nutrition 0.000 claims description 5
- 239000008267 milk Substances 0.000 claims description 5
- 210000004080 milk Anatomy 0.000 claims description 5
- 230000009885 systemic effect Effects 0.000 claims description 5
- MICBIPJWKDDGNL-UHFFFAOYSA-N 7',8'-dihydro-beta,psi-carotene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C MICBIPJWKDDGNL-UHFFFAOYSA-N 0.000 claims description 4
- 235000021012 strawberries Nutrition 0.000 claims description 4
- 229930003799 tocopherol Natural products 0.000 claims description 4
- 229960001295 tocopherol Drugs 0.000 claims description 4
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims description 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N (R)-alpha-Tocopherol Natural products OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 3
- 108010024636 Glutathione Proteins 0.000 claims description 3
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims description 3
- 239000002516 radical scavenger Substances 0.000 claims description 3
- 235000021013 raspberries Nutrition 0.000 claims description 3
- DMASLKHVQRHNES-UPOGUZCLSA-N (3R)-beta,beta-caroten-3-ol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C DMASLKHVQRHNES-UPOGUZCLSA-N 0.000 claims description 2
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 claims description 2
- 244000144927 Aloe barbadensis Species 0.000 claims description 2
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 2
- VYIRVAXUEZSDNC-LOFNIBRQSA-N Capsanthyn Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC(=O)C2(C)CC(O)CC2(C)C VYIRVAXUEZSDNC-LOFNIBRQSA-N 0.000 claims description 2
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 2
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 claims description 2
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 2
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 2
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 2
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 2
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 2
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 2
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 2
- 240000000171 Crataegus monogyna Species 0.000 claims description 2
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 2
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 2
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 2
- PANKHBYNKQNAHN-JTBLXSOISA-N Crocetin Natural products OC(=O)C(\C)=C/C=C/C(/C)=C\C=C\C=C(\C)/C=C/C=C(/C)C(O)=O PANKHBYNKQNAHN-JTBLXSOISA-N 0.000 claims description 2
- 239000004212 Cryptoxanthin Substances 0.000 claims description 2
- 235000007265 Myrrhis odorata Nutrition 0.000 claims description 2
- 235000017879 Nasturtium officinale Nutrition 0.000 claims description 2
- 240000005407 Nasturtium officinale Species 0.000 claims description 2
- 235000010735 Noci del Sudan Nutrition 0.000 claims description 2
- 240000004371 Panax ginseng Species 0.000 claims description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 2
- 235000000556 Paullinia cupana Nutrition 0.000 claims description 2
- 240000003444 Paullinia cupana Species 0.000 claims description 2
- 235000012550 Pimpinella anisum Nutrition 0.000 claims description 2
- 235000011158 Prunus mume Nutrition 0.000 claims description 2
- 244000018795 Prunus mume Species 0.000 claims description 2
- 244000178231 Rosmarinus officinalis Species 0.000 claims description 2
- 241000219094 Vitaceae Species 0.000 claims description 2
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 claims description 2
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 claims description 2
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 claims description 2
- 235000011399 aloe vera Nutrition 0.000 claims description 2
- 235000021028 berry Nutrition 0.000 claims description 2
- YRMTZGJDOCHJPY-UHFFFAOYSA-N beta-Zeacarotene Natural products CC(=CC=CC(=CCCC(=CCCC(=CC=CC=C(/C)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C)C)C)C)C YRMTZGJDOCHJPY-UHFFFAOYSA-N 0.000 claims description 2
- 235000002360 beta-cryptoxanthin Nutrition 0.000 claims description 2
- DMASLKHVQRHNES-ITUXNECMSA-N beta-cryptoxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CCCC2(C)C DMASLKHVQRHNES-ITUXNECMSA-N 0.000 claims description 2
- 235000018889 capsanthin Nutrition 0.000 claims description 2
- WRANYHFEXGNSND-LOFNIBRQSA-N capsanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC(=O)C2(C)CCC(O)C2(C)C WRANYHFEXGNSND-LOFNIBRQSA-N 0.000 claims description 2
- PANKHBYNKQNAHN-JUMCEFIXSA-N carotenoid dicarboxylic acid Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C(=O)O)C=CC=C(/C)C(=O)O PANKHBYNKQNAHN-JUMCEFIXSA-N 0.000 claims description 2
- 235000017471 coenzyme Q10 Nutrition 0.000 claims description 2
- 229940110767 coenzyme Q10 Drugs 0.000 claims description 2
- PANKHBYNKQNAHN-MQQNZMFNSA-N crocetin Chemical compound OC(=O)C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)C(O)=O PANKHBYNKQNAHN-MQQNZMFNSA-N 0.000 claims description 2
- 235000019244 cryptoxanthin Nutrition 0.000 claims description 2
- 235000008434 ginseng Nutrition 0.000 claims description 2
- 235000021021 grapes Nutrition 0.000 claims description 2
- 235000012680 lutein Nutrition 0.000 claims description 2
- 239000001656 lutein Substances 0.000 claims description 2
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims description 2
- 229960005375 lutein Drugs 0.000 claims description 2
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims description 2
- 235000012658 paprika extract Nutrition 0.000 claims description 2
- 239000001688 paprika extract Substances 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 230000002195 synergetic effect Effects 0.000 claims description 2
- 235000010384 tocopherol Nutrition 0.000 claims description 2
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims description 2
- 235000010930 zeaxanthin Nutrition 0.000 claims description 2
- 239000001775 zeaxanthin Substances 0.000 claims description 2
- 229940043269 zeaxanthin Drugs 0.000 claims description 2
- 230000003078 antioxidant effect Effects 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 3
- 125000002640 tocopherol group Chemical class 0.000 claims 3
- 229940123457 Free radical scavenger Drugs 0.000 claims 2
- 235000019149 tocopherols Nutrition 0.000 claims 2
- VYIRVAXUEZSDNC-TXDLOWMYSA-N (3R,3'S,5'R)-3,3'-dihydroxy-beta-kappa-caroten-6'-one Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC(=O)[C@]1(C)C[C@@H](O)CC1(C)C VYIRVAXUEZSDNC-TXDLOWMYSA-N 0.000 claims 1
- 241000722941 Achillea Species 0.000 claims 1
- 240000005528 Arctium lappa Species 0.000 claims 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims 1
- 241000490050 Eleutherococcus Species 0.000 claims 1
- 244000194101 Ginkgo biloba Species 0.000 claims 1
- 235000008100 Ginkgo biloba Nutrition 0.000 claims 1
- 240000009023 Myrrhis odorata Species 0.000 claims 1
- 229940087168 alpha tocopherol Drugs 0.000 claims 1
- 239000002361 compost Substances 0.000 claims 1
- 229960000984 tocofersolan Drugs 0.000 claims 1
- 235000004835 α-tocopherol Nutrition 0.000 claims 1
- 239000002076 α-tocopherol Substances 0.000 claims 1
- 125000001020 α-tocopherol group Chemical group 0.000 claims 1
- 235000019154 vitamin C Nutrition 0.000 description 12
- 239000011718 vitamin C Substances 0.000 description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 11
- 229930003268 Vitamin C Natural products 0.000 description 11
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 9
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 9
- 229930006000 Sucrose Natural products 0.000 description 8
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 8
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 8
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 8
- 229960002747 betacarotene Drugs 0.000 description 8
- FDSDTBUPSURDBL-LOFNIBRQSA-N canthaxanthin Chemical compound CC=1C(=O)CCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)CCC1(C)C FDSDTBUPSURDBL-LOFNIBRQSA-N 0.000 description 8
- 239000011719 vitamin A Substances 0.000 description 8
- 229940045997 vitamin a Drugs 0.000 description 8
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 7
- 239000004480 active ingredient Substances 0.000 description 7
- 239000000796 flavoring agent Substances 0.000 description 7
- 235000019634 flavors Nutrition 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 239000005720 sucrose Substances 0.000 description 7
- 235000019155 vitamin A Nutrition 0.000 description 7
- 235000019165 vitamin E Nutrition 0.000 description 7
- 239000011709 vitamin E Substances 0.000 description 7
- 244000299461 Theobroma cacao Species 0.000 description 6
- 229930003427 Vitamin E Natural products 0.000 description 6
- 239000000654 additive Substances 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- -1 e.g. Substances 0.000 description 6
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 235000000346 sugar Nutrition 0.000 description 6
- 229940046009 vitamin E Drugs 0.000 description 6
- 244000099147 Ananas comosus Species 0.000 description 5
- 235000007119 Ananas comosus Nutrition 0.000 description 5
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 description 5
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 description 5
- 235000009470 Theobroma cacao Nutrition 0.000 description 5
- 235000010385 ascorbyl palmitate Nutrition 0.000 description 5
- 239000003995 emulsifying agent Substances 0.000 description 5
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 5
- 235000012907 honey Nutrition 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 4
- 235000006679 Mentha X verticillata Nutrition 0.000 description 4
- 235000002899 Mentha suaveolens Nutrition 0.000 description 4
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 4
- OOUTWVMJGMVRQF-DOYZGLONSA-N Phoenicoxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C(=O)C(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)C(=O)CCC2(C)C OOUTWVMJGMVRQF-DOYZGLONSA-N 0.000 description 4
- 235000011034 Rubus glaucus Nutrition 0.000 description 4
- 235000009122 Rubus idaeus Nutrition 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- 235000012682 canthaxanthin Nutrition 0.000 description 4
- 239000001659 canthaxanthin Substances 0.000 description 4
- 229940008033 canthaxanthin Drugs 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 239000003223 protective agent Substances 0.000 description 4
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 235000016623 Fragaria vesca Nutrition 0.000 description 3
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 3
- 240000005979 Hordeum vulgare Species 0.000 description 3
- 235000007340 Hordeum vulgare Nutrition 0.000 description 3
- 240000004658 Medicago sativa Species 0.000 description 3
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 3
- 241000220317 Rosa Species 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
- 239000011149 active material Substances 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 235000015155 buttermilk Nutrition 0.000 description 3
- 235000005822 corn Nutrition 0.000 description 3
- 230000035622 drinking Effects 0.000 description 3
- 235000019197 fats Nutrition 0.000 description 3
- 235000015243 ice cream Nutrition 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 235000020357 syrup Nutrition 0.000 description 3
- 239000006188 syrup Substances 0.000 description 3
- 108010011485 Aspartame Proteins 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- 241000548268 Citrus deliciosa Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 235000000069 L-ascorbic acid Nutrition 0.000 description 2
- 239000002211 L-ascorbic acid Substances 0.000 description 2
- 235000010654 Melissa officinalis Nutrition 0.000 description 2
- 244000062730 Melissa officinalis Species 0.000 description 2
- 241001092459 Rubus Species 0.000 description 2
- 208000000453 Skin Neoplasms Diseases 0.000 description 2
- 239000000605 aspartame Substances 0.000 description 2
- 235000010357 aspartame Nutrition 0.000 description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 2
- 229960003438 aspartame Drugs 0.000 description 2
- 235000014121 butter Nutrition 0.000 description 2
- 235000008504 concentrate Nutrition 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 229940102465 ginger root Drugs 0.000 description 2
- 229960003180 glutathione Drugs 0.000 description 2
- 239000002960 lipid emulsion Substances 0.000 description 2
- 235000020094 liqueur Nutrition 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 229960003471 retinol Drugs 0.000 description 2
- 235000020944 retinol Nutrition 0.000 description 2
- 239000011607 retinol Substances 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 201000000849 skin cancer Diseases 0.000 description 2
- 235000014214 soft drink Nutrition 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 235000020354 squash Nutrition 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 239000003981 vehicle Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 239000001841 zingiber officinale Substances 0.000 description 2
- BQTOMHXDSCUCFR-PHPDKTIJSA-N 12'-apo-beta-carotenal Chemical compound O=CC(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C BQTOMHXDSCUCFR-PHPDKTIJSA-N 0.000 description 1
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 1
- 240000007087 Apium graveolens Species 0.000 description 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 1
- 235000010591 Appio Nutrition 0.000 description 1
- 206010003402 Arthropod sting Diseases 0.000 description 1
- 235000009467 Carica papaya Nutrition 0.000 description 1
- 240000006432 Carica papaya Species 0.000 description 1
- 240000005250 Chrysanthemum indicum Species 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 235000016795 Cola Nutrition 0.000 description 1
- 241001634499 Cola Species 0.000 description 1
- 235000011824 Cola pachycarpa Nutrition 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 235000017443 Hedysarum boreale Nutrition 0.000 description 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 description 1
- 150000000994 L-ascorbates Chemical class 0.000 description 1
- 235000014749 Mentha crispa Nutrition 0.000 description 1
- 244000078639 Mentha spicata Species 0.000 description 1
- 240000008188 Monarda punctata Species 0.000 description 1
- 241001495454 Parthenium Species 0.000 description 1
- AVFIYMSJDDGDBQ-UHFFFAOYSA-N Parthenium Chemical compound C1C=C(CCC(C)=O)C(C)CC2OC(=O)C(=C)C21 AVFIYMSJDDGDBQ-UHFFFAOYSA-N 0.000 description 1
- 244000062780 Petroselinum sativum Species 0.000 description 1
- 240000004760 Pimpinella anisum Species 0.000 description 1
- 244000235659 Rubus idaeus Species 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 240000001949 Taraxacum officinale Species 0.000 description 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 description 1
- 230000037338 UVA radiation Effects 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000010358 acesulfame potassium Nutrition 0.000 description 1
- 239000000619 acesulfame-K Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- DFMMVLFMMAQXHZ-CMGSAFQJSA-N apocarotenal Chemical compound O=CC(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)C=CC1=C(C)CCCC1(C)C DFMMVLFMMAQXHZ-CMGSAFQJSA-N 0.000 description 1
- 229940019834 apocarotenal Drugs 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000003952 beebalm Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- BQTOMHXDSCUCFR-HXGYUSFOSA-N beta-Apo-12'-carotenal Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=O BQTOMHXDSCUCFR-HXGYUSFOSA-N 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 230000001447 compensatory effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 235000001434 dietary modification Nutrition 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000000763 evoking effect Effects 0.000 description 1
- 235000002864 food coloring agent Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 235000014080 ginger ale Nutrition 0.000 description 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 description 1
- 235000021384 green leafy vegetables Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 235000015122 lemonade Nutrition 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000011824 nuclear material Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 235000011197 perejil Nutrition 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 235000011649 selenium Nutrition 0.000 description 1
- 235000020183 skimmed milk Nutrition 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 235000019263 trisodium citrate Nutrition 0.000 description 1
- 235000015192 vegetable juice Nutrition 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
- A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Mycology (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicines Containing Plant Substances (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Polymerisation Methods In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Description
NUTRmONAL SUN-EXPOSURE SUPPORTING COMPOSmON 0 9 0 7 9 4 /2 - 1 - NUTRITIONAL SUN-EXPOSURE SUPPORTING COMPOSITION The present invention relates to a nutritional soft drink containing carotenoids, which are useful as protecting agents against damages due to exposure to UV light, particularly skin cancer in humans.
It has been known for a long time that UV light is a major cause of skin cancer. The art employs numerous protecting agents against the dangers of exposure to UV light, particularly protective materials to be applied topically to the skin, such as sun ointments and lotions, be they water, alcohol or oil based, which contain photo-pro tectant materials.
This approach - so far the only effective approach widely used and accepted - has the considerable drawback of requiring high amounts of ·" active photo-protectant materials, eome of which have recently become suspect of becoming toxic under these conditions and in different ways harmful to health. Furthermore, obtaining a constant and uniform coverage of the skin with protecting ointments is difficult, and also the effectiveness of such protectants to defend the skin against UVA radiation is debatable.
Systemic carotenoids and antioxidants, both with and without Pro-Vitamin A activity, have been known for some time to be effective as protective agents against sun exposure hazards.
Recently, it has been suggested to increase carotenoids consumption by dietary modification or oral administration of carotenoid supplements, e.g., gelatin capsules and/or tablets. The said approach does not provide an optimal regime because appetite is decreased by exposure to sun and heat, and because intake of antioxidants in concentrated form, e.g., by swallowing tablets which should preferably be taken with meals, may expose to uneven dosages of antioxidants which may be associated with metabolic interference and even toxicity.
Such systemic approaches, furthermore, have the considerable drawback of being unsynchronized with the actual exposure to sunlight and therefore unnecessarily high - or ineffectively low - amounts of protective agents can be found in the system.
It is therefore clear that it would be highly desirable to provide a vehicle through which intake of carotenoids and other systemic photo-protectants can be applied in a proportional manner, without substantially exceeding the amount which is necessary for achieving substantial physiological protection from exposure to sun radiation, and/or exceeding the RDA generally accepted safe limitations.
It is an object of the present invention to provide a sun-exposure nutritional supporting drink which contains carotenoids as the basic photo-protectants, which overcomes the drawbacks of the methods known in the art and which provides compensatory increased levels of photo-protectants and antioxidants in the body when most needed, because they are quickly consumed or otherwise their concentration in the system decreases at a high rate, thus affording a systemic protective action. 1255 89 -3- The invention is therefore directed to a soft drink which contains a carotenoid mix, alone or together with vitamin C and/or vitamin E and/or other antioxidants, in an amount which does not exceed 10 Vitamin A RDA (Recommended Daily Allowance) equivalents of pro-Vitamin A carotenoids per liter of cool drink. Thus, intake of carotenoids and related photo-protectants is a function of exposure to sun and heat. The more exposed is the subject to the sun, the greater the amount of carotenoids that he will consume, because thirst and drinking responses are evoked proportionally to the extent/level of exposure to sun and heat.
It should be understood that the addition of Vitamins C and E or selenium to the carotenoids-containing drink has a synergistic effect, inasmuch as reduced glutathione (GSH) and Vitamin E are involved in the prevention of peroxidation of nuclear material, and Vitamin C, through its regenerating effect on Vitamin E is also active in this fashion. Thus, these additives can contribute protection in the initiation phase of skin damage, whereas carotenoids are rather effective in the later promotion stages of the photo-process.
Additional useful additives comprise antioxidants and factors directly or indirectly related to radical scavengers, such as GSH or Se, and CoQIO. These may be added as isolated materials or as naturally occurring components of vegetable/fruit juices and/or herbal preparations.
Normally a carotenoids mix will contain a number of carotenoids, such as β-carotene, canthaxanthin, zeaxanthin, lycopen, lutein, crocetin, 1255/89 -4- capsanthin, etc. The RDA equivalent of such a mix will be calculated based on the relative pro-Vitamin A activity of the carotenoids which do have pro- vitamin activity, e.g., β: 100%, a: 50-54%, γ:42-50%, β-zeacarotene: 20-40%, cryptoxanthin: 50-60%, P-apo-8'-carotenal: 72%, β-apo-12'-carotenal: 120%, etc., assuming that all the carotenoids with provitamin activity will be converted into Vitamin A.
Among the various advantages of the invention, it should be mentioned also that a drink is an excellent vehicle for the purposes of the invention, because it is generally accepted and proven that drinking in warm weather is beneficial. Furthermore, thirst can be induced by the addition of sugars or equivalent materials in relatively high proportions, to stimulate further drinking. Stimulation of the will to drink the mix according to the invention will be better achieved, of course, with tasty drinks.
Using the drink of the invention as the application method, the danger of overdosage becomes minimized, because overdosage may occur whenever a too-high amount of material is absorbed, which is not subsequently utilized by the body because it is not highly needed by the body as when exposed to sun in a manner that will prime the body to consume the photo-protectants. With the proportional intake of material through the drink according to the invention, this problem is inherently resolved.
It has further been found that Vitamin C protects carotenoids and, therefore, the addition of Vitamin C permits to operate with lower carotene concentrations, which is of course desirable. Furthermore, synergism between Vitamin C and Vitamin E exists, inasmuch as Vitamin E (tocopherol) is regenerated from tocopheryl radical by Vitamin C.
Vitamin C can also be supplied in other forms or precursors which can be metabolised to obtain Vitamin C, such as ascorbyl palmitate. Ascorbyl palmitate itself was found more effectively protecting carotene and internal organs, e.g., liver, against free radicals, when compared to ascorbic acid. This might be because it is easier to dissolve in fatty tissues.
While the limiting amount of pro-Vitamin A carotenoids and vitamins to be taken daily are of course the updated RDA, some examples of increased concentrations and other compositions to be used according to the invention will be detailed hereinafter. It is of course understood that the following examples are provided only for the purpose of illustration, and have no limiting purpose. Various flavors and additives detailed hereinafter are also detailed only by way of example, and a person skilled in the art will be able to provide additives, flavors and the like which match the drink which it is desired to provide.
Among the many additives which can be employed, tonic herbs are possible convenient additives, including, e.g., Borrage, Aloe-Vera, Peppermint, Lemon, Ginseng, Barley-water, Anise, Grapes, Raspberries, Strawberries, Hawthorn berries, Rosemary, Watercress, Guarana, Papavera Rhoea, Achilea Milfolia, Arcitium Lappaa, Chrysanthemum, Parthenium, Cola vera, Elentherococcus, Bingo Bilboa, Japanese apricot (UMA) etc.
The following examples of compositions will illustrate some of the many possible uses of the invention. While some examples of active material contents are specified hereinafter, the man of the art will appreciate that many different combinations of carotenoids and other active ingredients can be provided, depending on the requirements from the final composition concerning flavor, color, RDA, etc.
In general, addition of active materials can be done, e.g., by following the general directions given below.
Milk/Fat Soluble Liquids Fat emulsion carotenoid mix: β-carotene 30% suspension: 8 mg (for light drinks, e.g., Pina Colada) up to 25 mg (butter raspberry), 60 mg (cocoa), for each liter of cocoa/raspberry butter milk preparation. Apocarotenal (yellow-orange brown color), 30% fat emulsion base: 5-15 mg/liter for cocoa, and other coffee-based liquids and ices. Canthaxanthin 1% water soluble: 500-2000 mg/liter in strawberries and cocoa preparations, cc-tocopherol (e.g., Hoffmann-La Roche): 0-400 mg/liter drink.
Water-Based Drinks Carotenoid mix such as canthaxanthin 10% (water soluble) powder and β-carotene 1% powder. Dark drinks such as raspberries, strawberries or cola will contain (for each liter) the following: 350-2500 mg β-carotene 1%. and 500-1500 mg canthaxanthin 10%. Apo-carotene 30% fat 1255/89 -7- emulsifier base, 1:1 mixed with emulsifier for ginger ale: 5-15 mg/liter.
For light colored drinks, mostly β-carotene, e.g., 350 mg/liter for lemon drink and 700-2500 mg/liter for mint drinks.
Vitamin C: water soluble mix: L-ascorbic acid or ascorbate salts, according to taste considerations, between 50-2000 mg/liter. Ascorbyl palmitate (water insoluble) mix: 1 :1 ratio or ascorbyl palmitate and emulsifier: range of use: 200-8000 mg mix/liter drink.
Example 1 Instant Mandarin-Orange Powder A powder to be dissolved in water (130 g/liter) is prepared by admixing the following ingredients: 82.73% sucrose/white sugar, 10% flavorings (such as HNR flavor mandarin-orange 48230), 3% citric acid, 3% dextrose, 1% cloudifier (e.g., HNR). Buffers: 0.5% tri-sodium citrate, 0.5% tri-calcium phosphate. 0.2% ascorbic acid, 0.07 food color.
Diet version: Based on a sweetness index of sucrose = 1 , 1/200 parts of Aspartame or 1/250 parts of Acesulfame-K are substituted for each part of sugar.
To the above there are added 1-5 RDA equivalents of β-carotene and oc-tocopherol in water base emulsion and L-ascorbic acid (Hoffmann-La Roche) or ascorbyl palmitate (ICN Biochemicals).
Example 2 Orange Drink An orange drink can be prepared containing 150 g juice (10.5 BX) or 24.6 orange concentrate 64 BX, 89.25 g sucrose, 2.77 g lemon acid, flavors, stabilizers, buffer citrate (to prevent tartar) and extracts, 883.38 g water, carotenoids mix: 8 mg%, Vitamin C equivalent: 20 mg%.
The composition of the invention can also be provided in a milk/fat-water emulsion. The following are examples of such compositions.
Example 3 Instant Chocolate Beverage A formulation (8-10%/liter milk) will contain 67% sucrose/sugar, 30% cocoa powder, 1% lecithine and 2% satia gum, carotenoid mix, 6 mg%, Vitamin E, E.E. (a-tocopherol equivalent) 6 mg%, coenzyme Q10.
Example 4 Vegetarian Milk Base: Pinacolada The drink will contain 5% coconut oil, 0.1% emulsifiers, 8-10% sugar, 0.1% pinacolada flavor, and active ingredients as in the previous examples.
Example 5 Ice Cream An ice cream may contain about 10% of fat, 12% fat-free milk solids, 15% sugar, 3% corn syrup, color extracts and flavors, and active ingredients as in the previous examples.
Example 6 Raspberry Ice Butter-milk Butter-milk 61.45%, raspberry pulp 15.5%, sucrose 14%, corn syrup 6%, butter 3%, emulsifier (lecithine) 0.2%, stabilizers e.g., Lygomme ELB 0.2% (pH 3.8 4.0), active ingredients as in the previous examples.
Example 7 Camomille Summer Punch (Tonic) A strong infusion (concentrated hot-water herbal extract with or without 1/4 ethanol) with pineapple, papaya and honey. Add mint and strawberry cubes for color and taste. Active ingredients as defined above.
Example 8 Herbal (Mint) Drops A strong infusion: 4-8 teaspoons peppermint in 1 cup boiling water, steeping the infusion in a covered container for a few hours, refrigerated. 50 Drops added to lemonade drink. Active ingredients as defined above.
Example 9 Teas Rose Hip Tea Blend (cold Vitamin C drink): 1 cup dried rose hips, 1 3-inch stich cinnamon, 1/4 cup dried lemon balm leaves, 1 teaspoon dried grated organic lemon rind.
Rose Hip and Blackberry Cordial: 2 teabags rose hips (Pompadour brand), 1-2 teaspoons blackberry cordial, 1 cup boiling water. Steep together and serve.
Peppermint-Alfalfa Tea Blend: 1 cup peppermint or spearmint or bee balm leaves, 1 cup dried alfalfa leaves.
Active materials as defined above.
Example 10 Lemon Mint Blend Water preparation: 1/2 cup dried peppermint leaves, 1 cup dried alfalfa leaves, 3 tablespoons dried lemon balm leaves, 3 tablespoons dried, grated lemon rind. Solids: 1 teaspoon (250 g sucrose/liter). Active ingredients as defined above.
Example 11 Compound Barlev Water 2 pints simple barley water (4 ounces barley, whole, 2 ounces honey, lemon peel washed of 1/2 lemon: Add 1 pint of water to barley and lemon peel. Simmer until soft. Remove from heat. Steep. Add honey.), 1 pint hot water, 21/2 ounces sliced figs, 1/2 ounce, sliced and bruised licorice root, 21/2 ounces raisins. Boil down to 2 pints. Strain.
Example 12 Ginger Ale 1 large piece ginger root, bruised, 1 pint boiling water, 1 tablespoon honey, Perrier water as needed. Boil water, add bruised ginger root and simmer for fifteen to twenty minutes. Strain out root. Add honey and mix well. Combine with Perrier water. Don't use powdered ginger.
Example 13 Drink Powder "Orange Taste": (values expressed as percentage/content in the end user preparation): 10% sugar, 1% carotene mix. (Diet should be 1/200 aspartame or 1/250 acesulfam.) 0.1% citric acid. 0.9% tasters. 0.1-0.2% stabilizers (CMC, guargum, etc.). Buffer - Na3 citrate extracts.
As will be apparent from the above examples, preparing a mixed carotenoids drink according to the invention is simple and economic. It - 12- should be understood, as detailed above, that the word "drink" throughout this specification is meant to include also frozen or semi-frozen liquids, such as ice cream and Borbets.
Example 14 Fruit Ice Strawberry Sorbet Sucrose 21.5%, corn syrup (DE 36-38) 6.5%, strawberry puree 24.15%, strawberry concentrate 2.5%, satia algin GAX-900 0.35%. pH 3.3-3.5, water 45%.
Weed juice and pineapple: mint, alfalfa, filareo, dandelion, romaine leaves, parsley, celery tops, carrot tops, 2 cups pineapple: Combine handfuls and extract into juice. Place handfuls of these weeds and home greens in the juice extractor, use 1 cup to each 2 cups of pineapple. This green juice may be made into ice cubes and used.
Nutritional and RDA data for the components of the drink of the invention are well known to persons skilled in the art, and change from time to time. Illustrative data are reported below, based on values accepted at the time of filing of this application: RDA was formerly defined in terms of International Units, I.U., defined as 0.3 μg of crystalline all-trar\s retinol, or 0.6 .g β-carotene. Since 1980, RDA for Vitamin A is commonly stated in μ and R.E. For the adult male, the RDA is sot at 1000 RE (750 as retinol and 250 as β-cirotene, 5000 I.U.), while the RDA for women is lower, at 800 RE (4000 I.U.).
Children need 400 to 1000 RE (2000 to 5000 I.U.), increasing from infancy to 14 years. The amount of β-carotene required for 1 RE is 6 μg, while the amount required for other provitamin A carotenoids is 12 g. 1 RDA carotene is the provitamin A equivalent of 5000 I.U. Vitamin A.
Claims (12)
1. A synergistic food-stuff composition concentrate consisting essentially of (A) one or more edible carotenoids selected from the group consisting of q- , β , and ¾" carotenes, zeaxanthin, lycopen., lutein, crocetin, capsanthin, β -zeacarotene , cryptoxanthin, j3 &$o-8"-carotenal and^* —apo-12 "-carotenal; (B) water ; . (C) (1) at least one physiologically-acceptable antioxidant selected from the group consisting of ascorbic acid and salts thereof, and tocopherols; or (2) at least one physiologically-acceptable free-radical scavenger selected from the group consisting of reduced glutathione and coenzyme Q 10; or (3) at least one physiologically-acceptable antioxidant selected from the group consisting of ascorbic acid and salts thereof, and tocopherols, and at least one physiologically-acceptable free-radical scavenger selected from the group consisting of reduced glutathione and coenzyme Q10.
2. A food-stuff composition for oral consumption comprising an effective amount of the concentrate according to claim 1 for systemic protection against the harmful' effects of solar radiation, wherein the concentration of component (A) of the concentrate in said food-stuff compost ,tion does not exceed 10 times the U.S. recommended daily allowance for provitamin A active carotenoids per liter.
3. The composition of claim 2, further comprising a flavoring selected from the group consisting of borrage, aloe-vera, peppermint, lemon, ginseng, barley-water, anise, grapes,, raspberries, strawberries, hawthorn berries, rosemary, watercress, guarana, papavera rhoea, achillea milfolia, arcitium lappa, chrysanthemum, cola vera, eleutherococcus , ginkgo biloba and japanese apricot.
4. The composition of claim 2, wherein the antioxidant is ascorbic acid or a salt thereof.
5. The composition of claim 2, wherein the antioxidant is a tocopherol.
6. The composition of claim 1, wherein the antioxidant is an alpha tocopherol.
7. The composition of claim 2, wherein the composition is in an emulsified base.
8. ' 8. The composition of claim 2, wherein the composition IS in a milk base.
9. The composition of claim 2, wherein the composition is in a concentrated form.
10. The composition of claim 2, wherein the composition is in a drinkable form.
11. The composition of claim 2, wherein the composition is in a semi-frozen f rm.
12. The composition of claim 2, wherein the composition is in a frozen form. FOR THE APPLICANT By I. De Botton Patent Attorney
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9079489A IL90794A (en) | 1989-06-29 | 1989-06-29 | Nutritional sun-exposure supporting composition |
IT67467A IT1240963B (en) | 1989-06-29 | 1990-06-28 | NOURISHING COMPOSITION OF SUPPORT FOR SUN EXPOSURE. |
DE4020874A DE4020874A1 (en) | 1989-06-29 | 1990-06-29 | Soft drink giving protection against sun-light exposure - contains carotenoid and Vitamin=C or Vitamin=E |
US07/962,058 US5290605A (en) | 1989-06-29 | 1992-10-16 | Sun-exposure nutritional supporting composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9079489A IL90794A (en) | 1989-06-29 | 1989-06-29 | Nutritional sun-exposure supporting composition |
Publications (2)
Publication Number | Publication Date |
---|---|
IL90794A0 IL90794A0 (en) | 1990-01-18 |
IL90794A true IL90794A (en) | 1995-03-15 |
Family
ID=11060106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9079489A IL90794A (en) | 1989-06-29 | 1989-06-29 | Nutritional sun-exposure supporting composition |
Country Status (3)
Country | Link |
---|---|
DE (1) | DE4020874A1 (en) |
IL (1) | IL90794A (en) |
IT (1) | IT1240963B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9219524D0 (en) * | 1992-09-15 | 1992-10-28 | Smithkline Beecham Plc | Novel composition |
DE69303621T2 (en) * | 1992-11-19 | 1997-02-20 | Procter & Gamble | METHOD FOR IMPROVING THE BIOAVAILABILITY OF BETA-CAROTINE BY ADDING CALCIUM AND CARBOHYDRATES |
US6329432B2 (en) | 1993-06-28 | 2001-12-11 | The Howard Foundation | Mesozeaxanthin formulations for treatment of retinal disorders |
IL110139A0 (en) * | 1993-06-28 | 1994-10-07 | Howard Foundation | Pharmaceutically-active antioxidants |
GB9405041D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel process |
DE69636951T2 (en) * | 1995-06-07 | 2007-11-22 | The Howard Foundation, Cambridge | PHARMACEUTICALLY ACTIVE CAROTENOIDS |
DE19527281A1 (en) * | 1995-07-26 | 1997-01-30 | Hans Guenter Berner Gmbh | Food supplements |
DE19647352C2 (en) * | 1996-11-15 | 2000-06-29 | Aqua Nova Getraenketechnologie | Non-alcoholic beverage containing Q 10 |
US6784351B2 (en) | 2001-06-29 | 2004-08-31 | Ball Horticultural Company | Targetes erecta marigolds with altered carotenoid compositions and ratios |
US7081478B2 (en) | 2001-06-29 | 2006-07-25 | Chrysantis, Inc. | Mixed zeaxanthin ester concentrate and uses thereof |
US7575766B2 (en) | 2001-06-29 | 2009-08-18 | Ball Horticultural Company | Tagetes erecta with altered carotenoid compositions and ratios |
US7223909B2 (en) | 2002-03-21 | 2007-05-29 | Ball Horticultural | 4-ketocarotenoids in flower petals |
CH715855B1 (en) * | 2003-08-28 | 2020-08-14 | Mibelle Ag | Preparation consisting of at least two nanoemulsions. |
ATE456373T1 (en) * | 2004-11-29 | 2010-02-15 | Unilever Nv | ORAL COMPOSITION FOR IMPROVING SKIN PROPERTIES |
EP2952104A1 (en) | 2014-06-05 | 2015-12-09 | Böhm, Kirsten | Composition and method for preventing damage of human cells by ionising radiation |
-
1989
- 1989-06-29 IL IL9079489A patent/IL90794A/en unknown
-
1990
- 1990-06-28 IT IT67467A patent/IT1240963B/en active IP Right Grant
- 1990-06-29 DE DE4020874A patent/DE4020874A1/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
IT9067467A0 (en) | 1990-06-28 |
IT9067467A1 (en) | 1991-12-28 |
DE4020874A1 (en) | 1991-01-24 |
IL90794A0 (en) | 1990-01-18 |
IT1240963B (en) | 1993-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5290605A (en) | Sun-exposure nutritional supporting composition | |
ES2336546T3 (en) | COMPOSITIONS OF DRINKS THAT INCLUDE ARABINOGALACTAN AND A MINERAL SUPPLEMENT. | |
ES2269494T3 (en) | ANTIOXIDANT SYNERGIC COMBINATION OF DELTA-TOCOLES AND POLYPHENOLS. | |
US11134710B2 (en) | Cannabinoid emulsion product and process for making the same | |
EP1633209B1 (en) | Weight management beverage | |
KR100272487B1 (en) | Health drink composition | |
JP3492365B2 (en) | A method for enhancing the bioavailability of .BETA.-carotene | |
US20080044539A1 (en) | Astringency-compensated polyphenolic antioxidant-containing comestible composition | |
US20080199586A1 (en) | Nutritional herb and fruit beverage | |
IL90794A (en) | Nutritional sun-exposure supporting composition | |
MXPA06010674A (en) | Delivery of functional ingredients. | |
CA2580926A1 (en) | Compositions for anti-obesity, health-restorative and health-promotional benefits | |
CN102228103A (en) | Lemon and chrysanthemum tea beverage and preparation method thereof | |
US6576286B1 (en) | Cactus fruit drinks and food products | |
WO2007056307A2 (en) | Appetizer supplement to suppress age-related decline in capacity and appetite | |
KR20100128941A (en) | Functional composition for the prevention and improvement of hangover, and food and food additive having the same | |
Hedges et al. | Nutritional attributes of salad vegetables | |
US20050181083A1 (en) | Diet food product | |
US20160235104A1 (en) | All natural, nutritional, and flavorful frozen and liquid products and method of making same | |
KR102353626B1 (en) | Jelly-type Antler Drink and Its Manufacturing Method | |
WO2000067750A1 (en) | Food product | |
EP2229061A1 (en) | Flavoring agents | |
KR100496524B1 (en) | Composition for eliminating hangover | |
JP4141271B2 (en) | Citrus extract composition | |
KR100690071B1 (en) | Functional composition for the prevention and improvement of hangover |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed |