DE69634248D1 - Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen - Google Patents
Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffenInfo
- Publication number
- DE69634248D1 DE69634248D1 DE69634248T DE69634248T DE69634248D1 DE 69634248 D1 DE69634248 D1 DE 69634248D1 DE 69634248 T DE69634248 T DE 69634248T DE 69634248 T DE69634248 T DE 69634248T DE 69634248 D1 DE69634248 D1 DE 69634248D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- composition
- amylase
- sec
- digestability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000463 material Substances 0.000 title 1
- 102000013142 Amylases Human genes 0.000 abstract 3
- 108010065511 Amylases Proteins 0.000 abstract 3
- 102000004882 Lipase Human genes 0.000 abstract 3
- 108090001060 Lipase Proteins 0.000 abstract 3
- 239000004367 Lipase Substances 0.000 abstract 3
- 235000019418 amylase Nutrition 0.000 abstract 3
- 235000019421 lipase Nutrition 0.000 abstract 3
- 239000004382 Amylase Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 208000007848 Alcoholism Diseases 0.000 abstract 1
- 241000228245 Aspergillus niger Species 0.000 abstract 1
- 208000000668 Chronic Pancreatitis Diseases 0.000 abstract 1
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 1
- 206010033649 Pancreatitis chronic Diseases 0.000 abstract 1
- 241000588264 Rhizopus javanicus Species 0.000 abstract 1
- 240000005384 Rhizopus oryzae Species 0.000 abstract 1
- 235000013752 Rhizopus oryzae Nutrition 0.000 abstract 1
- 201000007930 alcohol dependence Diseases 0.000 abstract 1
- 229940025131 amylases Drugs 0.000 abstract 1
- 235000019621 digestibility Nutrition 0.000 abstract 1
- 210000003020 exocrine pancreas Anatomy 0.000 abstract 1
- 208000021045 exocrine pancreatic carcinoma Diseases 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 208000008443 pancreatic carcinoma Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95201438 | 1995-05-31 | ||
EP95201438 | 1995-05-31 | ||
PCT/EP1996/002407 WO1996038170A1 (en) | 1995-05-31 | 1996-05-31 | Composition to improve digestibility and utilisation of nutrients |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69634248D1 true DE69634248D1 (de) | 2005-03-03 |
DE69634248T2 DE69634248T2 (de) | 2006-01-12 |
Family
ID=8220345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69634248T Expired - Fee Related DE69634248T2 (de) | 1995-05-31 | 1996-05-31 | Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen |
Country Status (8)
Country | Link |
---|---|
US (1) | US6051220A (de) |
EP (1) | EP0828509B1 (de) |
AT (1) | ATE287725T1 (de) |
AU (1) | AU6221496A (de) |
CA (1) | CA2222682A1 (de) |
DE (1) | DE69634248T2 (de) |
ES (1) | ES2236738T3 (de) |
WO (1) | WO1996038170A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU750891B2 (en) | 1996-12-06 | 2002-08-01 | Aventis Pharmaceuticals Inc. | Polypeptides encoded by a human lipase-like gene, compositions and methods |
US6140475A (en) * | 1997-04-11 | 2000-10-31 | Altus Biologics Inc. | Controlled dissolution crosslinked protein crystals |
JP2000226335A (ja) * | 1998-12-04 | 2000-08-15 | Amano Pharmaceut Co Ltd | 経口用酵素製剤、酵素含有食材及び酵素製剤の服用方法 |
US20010046493A1 (en) * | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
AUPS076502A0 (en) * | 2002-02-26 | 2002-03-21 | Ceramic Fuel Cells Limited | A fuel cell gas separator plate |
US7142464B2 (en) * | 2003-04-29 | 2006-11-28 | Saifun Semiconductors Ltd. | Apparatus and methods for multi-level sensing in a memory array |
US20070087086A1 (en) * | 2003-12-02 | 2007-04-19 | Novozymes A/S | Method for producing potato products |
PT1729797E (pt) * | 2004-03-22 | 2008-12-17 | Solvay Pharm Gmbh | Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos |
WO2005115445A1 (en) * | 2004-05-24 | 2005-12-08 | Novozymes A/S | Enzymes for pharmaceutical use |
DK1809320T3 (da) * | 2004-10-14 | 2010-11-15 | Cystic Fibrosis Foundation The | Præparater indeholdende lipase, protease og amylase til behandling af pankreatisk insufficiens |
WO2006136161A2 (en) | 2005-06-24 | 2006-12-28 | Novozymes A/S | Amylases for pharmaceutical use |
US20070148151A1 (en) | 2005-07-29 | 2007-06-28 | Martin Frink | Processes for the manufacture and use of pancreatin |
US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
KR20080050506A (ko) * | 2005-09-20 | 2008-06-05 | 이데미쓰 고산 가부시키가이샤 | 동물용 사료 첨가제 |
MY151122A (en) * | 2005-10-05 | 2014-04-30 | Asahi Breweries Ltd | Method of producing filamentous fungus culture product |
US20100196344A1 (en) * | 2005-10-14 | 2010-08-05 | Cystic Fibrosis Foundation Therapeutics, Inc. | Compositions and methods for treating pancreatic insufficiency |
WO2007053619A2 (en) * | 2005-11-01 | 2007-05-10 | Bio-Cat, Inc. | A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
TWI609693B (zh) * | 2007-02-20 | 2018-01-01 | 艾泰醫藥有限公司 | 穩定之消化酵素組合物 |
WO2008103370A1 (en) | 2007-02-22 | 2008-08-28 | Children's Hospital And Research Center At Oakland | Fatty acid formulations and methods of use thereof |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
WO2009071550A1 (en) * | 2007-12-04 | 2009-06-11 | Novozymes A/S | Protease variants for pharmaceutical use |
WO2009109856A2 (en) | 2008-03-07 | 2009-09-11 | Axcan Pharma Inc. | Method for detecting infectious parvovirus in pharmaceutical preparations |
US20110171294A1 (en) * | 2008-09-30 | 2011-07-14 | Dsm Ip Assets B.V. | Enzyme composition and application thereof in the treatment of pancreatic insufficiency |
WO2010130622A1 (en) * | 2009-05-11 | 2010-11-18 | Dsm Ip Assets B.V. | Enzyme composition for the treatment of prancreatic insufficiency |
RU2012142134A (ru) * | 2010-03-19 | 2014-04-27 | Апталис Фарма Кэнэда Инк. | Желудочно-резистентные ферментные фармацевтические композиции |
EA030450B1 (ru) | 2010-10-01 | 2018-08-31 | Апталис Фарма Лимитид | Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием |
ES2734221T3 (es) | 2011-08-08 | 2019-12-04 | Allergan Pharmaceuticals Int Ltd | Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas |
US8268305B1 (en) | 2011-09-23 | 2012-09-18 | Bio-Cat, Inc. | Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase |
PL2897604T3 (pl) | 2012-09-19 | 2018-10-31 | Grespo Ab | Kompozycje do ulepszenia funkcji mózgu |
ES2707211T3 (es) | 2013-03-15 | 2019-04-02 | Allergan Pharmaceuticals Int Ltd | Proceso para la preparación de una composición que contiene enzimas digestivas y nutrientes adecuada para su administración enteral |
AU2014304176A1 (en) | 2013-07-22 | 2016-02-11 | Aptalis Pharma Ltd. | High potency pancreatin pharmaceutical compositions |
ES2784227T3 (es) | 2013-08-09 | 2020-09-23 | Allergan Pharmaceuticals Int Ltd | Composición de enzimas digestivos adecuada para la administración entérica |
CN106659773A (zh) | 2013-11-05 | 2017-05-10 | 阿勒根制药国际有限公司 | 高效的胰酶药物组合物 |
CA2947998A1 (en) | 2014-06-19 | 2015-12-23 | Aptalis Pharma Ltd. | Methods for removing viral contaminants from pancreatic extracts |
GB201501081D0 (en) * | 2015-01-22 | 2015-03-11 | Cilian Ag | Use of enzymes with a wide pH activity range as medicaments for promoting digestion |
US20180028454A1 (en) | 2015-02-04 | 2018-02-01 | Abbvie Inc. | Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency |
FR3079146B1 (fr) | 2018-03-23 | 2020-04-17 | Karim Ioualalen | Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1084431A (en) * | 1964-05-06 | 1967-09-20 | Analyses Et De Rech S Biolog M | Improvements in and relating to lipases |
DE2638088C3 (de) * | 1976-08-24 | 1979-06-21 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Verwendung von SuBmolkenpulver |
FR2362863A1 (fr) * | 1976-08-24 | 1978-03-24 | Degussa | Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale |
DE69004301T2 (de) * | 1989-03-08 | 1994-03-24 | Simon Lodewijk Scharpe | Mischung zur Behandlung der von exokrinen Insuffizienz der Bauchspeicheldrüse und die Verwendung der genannten Mischung. |
BE1005445A3 (fr) * | 1991-10-16 | 1993-07-27 | Enzymes And Derivates Belgium | Compositions enzymatiques d'aide a la digestion. |
US5260074A (en) * | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
-
1996
- 1996-05-31 AT AT96920782T patent/ATE287725T1/de not_active IP Right Cessation
- 1996-05-31 CA CA002222682A patent/CA2222682A1/en not_active Abandoned
- 1996-05-31 DE DE69634248T patent/DE69634248T2/de not_active Expired - Fee Related
- 1996-05-31 WO PCT/EP1996/002407 patent/WO1996038170A1/en active IP Right Grant
- 1996-05-31 AU AU62214/96A patent/AU6221496A/en not_active Abandoned
- 1996-05-31 ES ES96920782T patent/ES2236738T3/es not_active Expired - Lifetime
- 1996-05-31 US US08/973,031 patent/US6051220A/en not_active Expired - Fee Related
- 1996-05-31 EP EP96920782A patent/EP0828509B1/de not_active Revoked
Also Published As
Publication number | Publication date |
---|---|
EP0828509B1 (de) | 2005-01-26 |
US6051220A (en) | 2000-04-18 |
ES2236738T3 (es) | 2005-07-16 |
ATE287725T1 (de) | 2005-02-15 |
AU6221496A (en) | 1996-12-18 |
EP0828509A1 (de) | 1998-03-18 |
DE69634248T2 (de) | 2006-01-12 |
CA2222682A1 (en) | 1996-12-05 |
WO1996038170A1 (en) | 1996-12-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8339 | Ceased/non-payment of the annual fee |