DE69634248D1 - Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen - Google Patents

Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen

Info

Publication number
DE69634248D1
DE69634248D1 DE69634248T DE69634248T DE69634248D1 DE 69634248 D1 DE69634248 D1 DE 69634248D1 DE 69634248 T DE69634248 T DE 69634248T DE 69634248 T DE69634248 T DE 69634248T DE 69634248 D1 DE69634248 D1 DE 69634248D1
Authority
DE
Germany
Prior art keywords
pct
composition
amylase
sec
digestability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69634248T
Other languages
English (en)
Other versions
DE69634248T2 (de
Inventor
Lodewijk Scharpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medzyme NV
Original Assignee
Medzyme NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8220345&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69634248(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medzyme NV filed Critical Medzyme NV
Publication of DE69634248D1 publication Critical patent/DE69634248D1/de
Application granted granted Critical
Publication of DE69634248T2 publication Critical patent/DE69634248T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
DE69634248T 1995-05-31 1996-05-31 Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen Expired - Fee Related DE69634248T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95201438 1995-05-31
EP95201438 1995-05-31
PCT/EP1996/002407 WO1996038170A1 (en) 1995-05-31 1996-05-31 Composition to improve digestibility and utilisation of nutrients

Publications (2)

Publication Number Publication Date
DE69634248D1 true DE69634248D1 (de) 2005-03-03
DE69634248T2 DE69634248T2 (de) 2006-01-12

Family

ID=8220345

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69634248T Expired - Fee Related DE69634248T2 (de) 1995-05-31 1996-05-31 Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen

Country Status (8)

Country Link
US (1) US6051220A (de)
EP (1) EP0828509B1 (de)
AT (1) ATE287725T1 (de)
AU (1) AU6221496A (de)
CA (1) CA2222682A1 (de)
DE (1) DE69634248T2 (de)
ES (1) ES2236738T3 (de)
WO (1) WO1996038170A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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AU750891B2 (en) 1996-12-06 2002-08-01 Aventis Pharmaceuticals Inc. Polypeptides encoded by a human lipase-like gene, compositions and methods
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
JP2000226335A (ja) * 1998-12-04 2000-08-15 Amano Pharmaceut Co Ltd 経口用酵素製剤、酵素含有食材及び酵素製剤の服用方法
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
AUPS076502A0 (en) * 2002-02-26 2002-03-21 Ceramic Fuel Cells Limited A fuel cell gas separator plate
US7142464B2 (en) * 2003-04-29 2006-11-28 Saifun Semiconductors Ltd. Apparatus and methods for multi-level sensing in a memory array
US20070087086A1 (en) * 2003-12-02 2007-04-19 Novozymes A/S Method for producing potato products
PT1729797E (pt) * 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
WO2005115445A1 (en) * 2004-05-24 2005-12-08 Novozymes A/S Enzymes for pharmaceutical use
DK1809320T3 (da) * 2004-10-14 2010-11-15 Cystic Fibrosis Foundation The Præparater indeholdende lipase, protease og amylase til behandling af pankreatisk insufficiens
WO2006136161A2 (en) 2005-06-24 2006-12-28 Novozymes A/S Amylases for pharmaceutical use
US20070148151A1 (en) 2005-07-29 2007-06-28 Martin Frink Processes for the manufacture and use of pancreatin
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) * 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
KR20080050506A (ko) * 2005-09-20 2008-06-05 이데미쓰 고산 가부시키가이샤 동물용 사료 첨가제
MY151122A (en) * 2005-10-05 2014-04-30 Asahi Breweries Ltd Method of producing filamentous fungus culture product
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
WO2007053619A2 (en) * 2005-11-01 2007-05-10 Bio-Cat, Inc. A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency
US10072256B2 (en) * 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
TWI609693B (zh) * 2007-02-20 2018-01-01 艾泰醫藥有限公司 穩定之消化酵素組合物
WO2008103370A1 (en) 2007-02-22 2008-08-28 Children's Hospital And Research Center At Oakland Fatty acid formulations and methods of use thereof
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
WO2009071550A1 (en) * 2007-12-04 2009-06-11 Novozymes A/S Protease variants for pharmaceutical use
WO2009109856A2 (en) 2008-03-07 2009-09-11 Axcan Pharma Inc. Method for detecting infectious parvovirus in pharmaceutical preparations
US20110171294A1 (en) * 2008-09-30 2011-07-14 Dsm Ip Assets B.V. Enzyme composition and application thereof in the treatment of pancreatic insufficiency
WO2010130622A1 (en) * 2009-05-11 2010-11-18 Dsm Ip Assets B.V. Enzyme composition for the treatment of prancreatic insufficiency
RU2012142134A (ru) * 2010-03-19 2014-04-27 Апталис Фарма Кэнэда Инк. Желудочно-резистентные ферментные фармацевтические композиции
EA030450B1 (ru) 2010-10-01 2018-08-31 Апталис Фарма Лимитид Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием
ES2734221T3 (es) 2011-08-08 2019-12-04 Allergan Pharmaceuticals Int Ltd Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
PL2897604T3 (pl) 2012-09-19 2018-10-31 Grespo Ab Kompozycje do ulepszenia funkcji mózgu
ES2707211T3 (es) 2013-03-15 2019-04-02 Allergan Pharmaceuticals Int Ltd Proceso para la preparación de una composición que contiene enzimas digestivas y nutrientes adecuada para su administración enteral
AU2014304176A1 (en) 2013-07-22 2016-02-11 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
ES2784227T3 (es) 2013-08-09 2020-09-23 Allergan Pharmaceuticals Int Ltd Composición de enzimas digestivos adecuada para la administración entérica
CN106659773A (zh) 2013-11-05 2017-05-10 阿勒根制药国际有限公司 高效的胰酶药物组合物
CA2947998A1 (en) 2014-06-19 2015-12-23 Aptalis Pharma Ltd. Methods for removing viral contaminants from pancreatic extracts
GB201501081D0 (en) * 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
US20180028454A1 (en) 2015-02-04 2018-02-01 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
FR3079146B1 (fr) 2018-03-23 2020-04-17 Karim Ioualalen Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1084431A (en) * 1964-05-06 1967-09-20 Analyses Et De Rech S Biolog M Improvements in and relating to lipases
DE2638088C3 (de) * 1976-08-24 1979-06-21 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verwendung von SuBmolkenpulver
FR2362863A1 (fr) * 1976-08-24 1978-03-24 Degussa Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale
DE69004301T2 (de) * 1989-03-08 1994-03-24 Simon Lodewijk Scharpe Mischung zur Behandlung der von exokrinen Insuffizienz der Bauchspeicheldrüse und die Verwendung der genannten Mischung.
BE1005445A3 (fr) * 1991-10-16 1993-07-27 Enzymes And Derivates Belgium Compositions enzymatiques d'aide a la digestion.
US5260074A (en) * 1992-06-22 1993-11-09 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof

Also Published As

Publication number Publication date
EP0828509B1 (de) 2005-01-26
US6051220A (en) 2000-04-18
ES2236738T3 (es) 2005-07-16
ATE287725T1 (de) 2005-02-15
AU6221496A (en) 1996-12-18
EP0828509A1 (de) 1998-03-18
DE69634248T2 (de) 2006-01-12
CA2222682A1 (en) 1996-12-05
WO1996038170A1 (en) 1996-12-05

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee