FR2362863A1 - Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale - Google Patents

Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale

Info

Publication number
FR2362863A1
FR2362863A1 FR7725374A FR7725374A FR2362863A1 FR 2362863 A1 FR2362863 A1 FR 2362863A1 FR 7725374 A FR7725374 A FR 7725374A FR 7725374 A FR7725374 A FR 7725374A FR 2362863 A1 FR2362863 A1 FR 2362863A1
Authority
FR
France
Prior art keywords
lipases
preparations
animal origin
improved medical
enhanced action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7725374A
Other languages
English (en)
Other versions
FR2362863B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762638088 external-priority patent/DE2638088C3/de
Priority claimed from DE19762638089 external-priority patent/DE2638089C2/de
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of FR2362863A1 publication Critical patent/FR2362863A1/fr
Application granted granted Critical
Publication of FR2362863B1 publication Critical patent/FR2362863B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Ces préparations d'enzymes contenant des lipases sont caractérisées par la présence comme stabilisant de 10 à 50 parties en poids (par partie en poids de lipase) d'un mélange constitué par 40 à 90 % de lactose, 8 à 50 % de protéines du petit-lait, 0,1 à 7 % de matières grasses du lait, 0,1 à 10 % de composés minéraux du petit-lait et 0,1 à 5 % d'eau, ces pourcentages étant donnés en poids. La stabilité et l'activité enzymatique de ces préparations sont accrues et si les lipases ne sont pas d'origine animale, les préparations définies ci-dessus sont utilisables comme médicaments dans le traitement des troubles digestifs.
FR7725374A 1976-08-24 1977-08-19 Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale Granted FR2362863A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762638088 DE2638088C3 (de) 1976-08-24 1976-08-24 Verwendung von SuBmolkenpulver
DE19762638089 DE2638089C2 (de) 1976-08-24 1976-08-24 Lipase-Präparate mit verbesserter Wirkung

Publications (2)

Publication Number Publication Date
FR2362863A1 true FR2362863A1 (fr) 1978-03-24
FR2362863B1 FR2362863B1 (fr) 1981-07-03

Family

ID=25770834

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7725374A Granted FR2362863A1 (fr) 1976-08-24 1977-08-19 Preparations de lipases a action amelioree et preparations medicales ameliorees contenant des lipases d'origine non animale

Country Status (2)

Country Link
FR (1) FR2362863A1 (fr)
GB (1) GB1546328A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2236738T3 (es) * 1995-05-31 2005-07-16 Medzyme N.V. Composicion para mejorar la digestibilidad y la utilizacion de nutrientes.
MY142014A (en) * 2004-04-08 2010-08-16 Nisshin Oillio Group Ltd A lipase powder, methods for producing the same and use thereof
DE102008006716A1 (de) * 2008-01-30 2009-08-13 BAM Bundesanstalt für Materialforschung und -prüfung Lipasenformulierung
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081225A (en) * 1962-03-28 1963-03-12 Dairyland Food Lab Enzyme treatment for "scours" in animals
US3256150A (en) * 1964-04-20 1966-06-14 Dairyland Food Lab Method for treating malabsorption syndrome

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081225A (en) * 1962-03-28 1963-03-12 Dairyland Food Lab Enzyme treatment for "scours" in animals
US3256150A (en) * 1964-04-20 1966-06-14 Dairyland Food Lab Method for treating malabsorption syndrome

Also Published As

Publication number Publication date
FR2362863B1 (fr) 1981-07-03
GB1546328A (en) 1979-05-23

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Legal Events

Date Code Title Description
ST Notification of lapse