DE69632407T2 - Antikörper gegen l-selectin zur vorbeugung von multiplem organversagen und akuter organschädigung - Google Patents

Antikörper gegen l-selectin zur vorbeugung von multiplem organversagen und akuter organschädigung Download PDF

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Publication number
DE69632407T2
DE69632407T2 DE69632407T DE69632407T DE69632407T2 DE 69632407 T2 DE69632407 T2 DE 69632407T2 DE 69632407 T DE69632407 T DE 69632407T DE 69632407 T DE69632407 T DE 69632407T DE 69632407 T2 DE69632407 T2 DE 69632407T2
Authority
DE
Germany
Prior art keywords
selectin
antibody
antibodies
hudreg
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69632407T
Other languages
German (de)
English (en)
Other versions
DE69632407D1 (de
Inventor
Anton Haselbeck
Günther Schumacher
Sung Man CO
Ulrich Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PDL Biopharma Inc
Original Assignee
Protein Design Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Design Labs Inc filed Critical Protein Design Labs Inc
Application granted granted Critical
Publication of DE69632407D1 publication Critical patent/DE69632407D1/de
Publication of DE69632407T2 publication Critical patent/DE69632407T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69632407T 1995-08-17 1996-08-14 Antikörper gegen l-selectin zur vorbeugung von multiplem organversagen und akuter organschädigung Expired - Fee Related DE69632407T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP95112895 1995-08-17
EP95112895 1995-08-17
EP95114696 1995-09-19
EP95114696 1995-09-19
US57895395A 1995-12-27 1995-12-27
US578953 1995-12-27
PCT/US1996/013152 WO1997006822A1 (en) 1995-08-17 1996-08-14 Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage

Publications (2)

Publication Number Publication Date
DE69632407D1 DE69632407D1 (de) 2004-06-09
DE69632407T2 true DE69632407T2 (de) 2005-06-02

Family

ID=27236574

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69632407T Expired - Fee Related DE69632407T2 (de) 1995-08-17 1996-08-14 Antikörper gegen l-selectin zur vorbeugung von multiplem organversagen und akuter organschädigung

Country Status (11)

Country Link
EP (1) EP0868197B1 (enExample)
JP (1) JP3604699B2 (enExample)
AT (1) ATE265861T1 (enExample)
AU (1) AU6773596A (enExample)
CA (1) CA2229140A1 (enExample)
CZ (1) CZ45498A3 (enExample)
DE (1) DE69632407T2 (enExample)
HU (1) HUP9901673A3 (enExample)
PL (1) PL187090B1 (enExample)
WO (1) WO1997006822A1 (enExample)
ZA (1) ZA966954B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172213B1 (en) 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
US5994511A (en) 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
GB9919713D0 (en) * 1999-08-19 1999-10-20 Queen Mary & Westfield College New medical use of high density lipoprotein
MY147019A (en) 2002-03-13 2012-10-15 Biogen Idec Inc Anti-alpha v beta 6 antibodies
CN102875681A (zh) * 2005-07-08 2013-01-16 拜奥根Idec马萨诸塞公司 抗-αvβ6抗体及其用途
BRPI0714381A2 (pt) 2006-07-10 2013-03-05 Biogen Idec Inc composiÇÕes e mÉtodos para inibir crescimento de cÂnceres deficientes em smad4
WO2014143739A2 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
US10035859B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
CN113348011B (zh) 2018-11-19 2023-04-18 比奥拉治疗股份有限公司 用生物治疗剂治疗疾病的方法和装置
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69232780T2 (de) * 1991-06-25 2003-01-30 Dana-Farber Cancer Institute, Boston Monoklonaler antikörper gegen lymphozytenassoziiertes zelloberflächenprotein
AU2410292A (en) * 1991-07-29 1993-03-02 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies to leukocyte adhesion molecule-1
RU2151612C1 (ru) * 1992-12-01 2000-06-27 Протеин Дизайн Лэбс, Инк. Гуманизированный иммуноглобулин, специфичный для белка l-селектина человека
AU2185195A (en) * 1993-11-30 1995-06-19 Protein Design Labs, Inc. Reperfusion therapy using antibodies to L-selectin

Also Published As

Publication number Publication date
HUP9901673A3 (en) 2001-06-28
ATE265861T1 (de) 2004-05-15
HUP9901673A2 (hu) 1999-08-30
CA2229140A1 (en) 1997-02-27
EP0868197B1 (en) 2004-05-06
PL187090B1 (pl) 2004-05-31
JP3604699B2 (ja) 2004-12-22
ZA966954B (en) 1998-02-16
DE69632407D1 (de) 2004-06-09
JPH10510553A (ja) 1998-10-13
EP0868197A4 (enExample) 1998-11-18
PL325012A1 (en) 1998-07-06
EP0868197A1 (en) 1998-10-07
WO1997006822A1 (en) 1997-02-27
CZ45498A3 (cs) 1999-01-13
AU6773596A (en) 1997-03-12

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee