DE69518415T2 - Arznei für rheumatoide arthritis - Google Patents

Arznei für rheumatoide arthritis

Info

Publication number
DE69518415T2
DE69518415T2 DE69518415T DE69518415T DE69518415T2 DE 69518415 T2 DE69518415 T2 DE 69518415T2 DE 69518415 T DE69518415 T DE 69518415T DE 69518415 T DE69518415 T DE 69518415T DE 69518415 T2 DE69518415 T2 DE 69518415T2
Authority
DE
Germany
Prior art keywords
rheumatoid arthritis
medicine
remedy
monoclonal antibody
antibody recognizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69518415T
Other languages
English (en)
Other versions
DE69518415D1 (de
Inventor
Tadashi Nishida
Sachiko Miyake
Hideo Yagita
Ko Okumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Publication of DE69518415D1 publication Critical patent/DE69518415D1/de
Application granted granted Critical
Publication of DE69518415T2 publication Critical patent/DE69518415T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69518415T 1994-04-26 1995-03-22 Arznei für rheumatoide arthritis Expired - Fee Related DE69518415T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8825194 1994-04-26
PCT/JP1995/000527 WO1995028961A1 (fr) 1994-04-26 1995-03-22 Medicament pour polyarthrite rhumatoide

Publications (2)

Publication Number Publication Date
DE69518415D1 DE69518415D1 (de) 2000-09-21
DE69518415T2 true DE69518415T2 (de) 2001-01-25

Family

ID=13937651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69518415T Expired - Fee Related DE69518415T2 (de) 1994-04-26 1995-03-22 Arznei für rheumatoide arthritis

Country Status (9)

Country Link
US (1) US5855888A (de)
EP (1) EP0759302B1 (de)
AT (1) ATE195428T1 (de)
DE (1) DE69518415T2 (de)
DK (1) DK0759302T3 (de)
ES (1) ES2151054T3 (de)
GR (1) GR3034200T3 (de)
PT (1) PT759302E (de)
WO (1) WO1995028961A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121151B1 (de) * 1998-10-07 2006-12-13 Lennart Lindbom Anti-entzündliche alpha2, beta1 integrin-verwandte substanzen oder antikörper
EA006681B1 (ru) * 1999-04-22 2006-02-24 Байоджен Айдек Ма Инк. Применение антагонистов взаимодействия vla-4 и альфа-4-бета-7 с соответствующими альфа-4-лигандами для лечения фиброза
WO2000072881A1 (en) 1999-06-01 2000-12-07 Biogen, Inc. A blocking monoclonal antibody to vla-1 and its use for the treatment of inflammatory disorders
US6146639A (en) * 1999-07-26 2000-11-14 Merich Nick Arthritis, muscle pain, and dry skin remedy
US7358054B2 (en) 2001-04-13 2008-04-15 Biogen Idec Ma Inc. Antibodies to VLA-1
US20030013107A1 (en) * 2001-06-07 2003-01-16 Rigel Pharmaceuticals, Incorporated Alpha 2 integrin: modulators of lymphocyte activation
ES2541302T3 (es) * 2005-11-18 2015-07-17 Glenmark Pharmaceuticals S.A. Anticuerpos anti-integrina alfa2 y sus usos
CN105381459A (zh) * 2006-05-25 2016-03-09 比奥根Ma公司 治疗中风的方法
US20080267978A1 (en) * 2006-08-28 2008-10-30 Mary Zutter Anti-angiogenic targets for cancer therapy
EP2710037B1 (de) * 2011-05-19 2019-07-31 The Regents of The University of Michigan Alpha-2-integrin-bindemittel und verwendung zur hemmung der krebszellenproliferation
CN104271122A (zh) 2012-02-16 2015-01-07 桑塔鲁斯股份有限公司 抗vla1(cd49a)抗体药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330506A3 (de) * 1988-02-26 1990-06-20 Dana Farber Cancer Institute VLA-Proteine
DK162890D0 (da) * 1990-07-06 1990-07-06 Novo Nordisk As Polypeptid
DE69233628T2 (de) * 1991-07-25 2007-04-26 Biogen Idec Inc., San Diego Rekombinante Antikörper zur humanen Therapie

Also Published As

Publication number Publication date
DK0759302T3 (da) 2000-11-13
GR3034200T3 (en) 2000-11-30
EP0759302A4 (de) 1997-11-19
EP0759302B1 (de) 2000-08-16
EP0759302A1 (de) 1997-02-26
ES2151054T3 (es) 2000-12-16
US5855888A (en) 1999-01-05
DE69518415D1 (de) 2000-09-21
PT759302E (pt) 2001-01-31
ATE195428T1 (de) 2000-09-15
WO1995028961A1 (fr) 1995-11-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: AKZO NOBEL N.V., ARNHEIM/ARNHEM, NL

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee