DE69630460D1 - Flurbiprofenhaltige arzneimittel - Google Patents

Flurbiprofenhaltige arzneimittel

Info

Publication number
DE69630460D1
DE69630460D1 DE69630460T DE69630460T DE69630460D1 DE 69630460 D1 DE69630460 D1 DE 69630460D1 DE 69630460 T DE69630460 T DE 69630460T DE 69630460 T DE69630460 T DE 69630460T DE 69630460 D1 DE69630460 D1 DE 69630460D1
Authority
DE
Germany
Prior art keywords
flurbi
products containing
medicinal products
sugar
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69630460T
Other languages
English (en)
Other versions
DE69630460T2 (de
Inventor
David Michael Barrett
Carl Simon Smith
David Michael Thurgood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of DE69630460D1 publication Critical patent/DE69630460D1/de
Application granted granted Critical
Publication of DE69630460T2 publication Critical patent/DE69630460T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DE69630460T 1995-11-22 1996-11-21 Flurbiprofenhaltige arzneimittel Expired - Lifetime DE69630460T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9523833 1995-11-22
GBGB9523833.3A GB9523833D0 (en) 1995-11-22 1995-11-22 Medical treatment
PCT/EP1996/005208 WO1997018802A1 (en) 1995-11-22 1996-11-21 Pharmaceutical compositions comprising flurbiprofen

Publications (2)

Publication Number Publication Date
DE69630460D1 true DE69630460D1 (de) 2003-11-27
DE69630460T2 DE69630460T2 (de) 2004-08-19

Family

ID=10784245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69630460T Expired - Lifetime DE69630460T2 (de) 1995-11-22 1996-11-21 Flurbiprofenhaltige arzneimittel

Country Status (21)

Country Link
US (2) US5889057A (de)
EP (1) EP0862424B1 (de)
CN (1) CN1148177C (de)
AT (1) ATE252382T1 (de)
AU (1) AU707749B2 (de)
BG (1) BG64166B1 (de)
CA (1) CA2238271C (de)
CZ (1) CZ289643B6 (de)
DE (1) DE69630460T2 (de)
DK (1) DK0862424T3 (de)
ES (1) ES2208768T3 (de)
GB (1) GB9523833D0 (de)
HU (1) HU225235B1 (de)
IL (1) IL124568A0 (de)
NO (1) NO317287B1 (de)
NZ (1) NZ322933A (de)
PT (1) PT862424E (de)
RU (1) RU2203655C2 (de)
SK (1) SK284092B6 (de)
UA (1) UA46807C2 (de)
WO (1) WO1997018802A1 (de)

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GB9710521D0 (en) * 1997-05-22 1997-07-16 Boots Co Plc Process
WO1998052540A1 (en) * 1997-05-22 1998-11-26 The Boots Company Plc Pharmaceutical compositions
AU7916798A (en) * 1997-05-22 1998-12-11 Boots Company Plc, The Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat
EP1206283A2 (de) * 1999-05-17 2002-05-22 Aesgen, Inc. Verbesserte zelluläre aufnahme von bioaktiven wirkstoffen
CA2406383A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research A.beta.42 lowering agents
JP2005509002A (ja) * 2001-11-13 2005-04-07 ファルマシア コーポレイション スルホンアミドプロドラックの経口剤形
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
MXPA05001267A (es) * 2002-08-01 2005-10-18 Aesgen Inc Tratamiento mejorado de cancer con glutamina.
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
US20040265359A1 (en) * 2003-04-17 2004-12-30 Sacks Gordon S. Oral delivery formulations of L-glutamine
EP1651195A4 (de) * 2003-07-11 2007-10-03 Myriad Genetics Inc Pharmazeutische verfahren, dosierschemata und dosierformen zur behandlung von alzheimerkrankheit
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
AU2005241023A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
CA2618985A1 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
GB2423710A (en) * 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
WO2007014124A2 (en) * 2005-07-22 2007-02-01 Myriad Genetics, Inc. High drug load formulations and dosage forms
RU2008116871A (ru) * 2005-11-02 2009-12-10 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US) Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения
US7282224B1 (en) * 2006-06-09 2007-10-16 Guthy-Renker Corporation Pain relief composition
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
US7754234B2 (en) * 2006-07-12 2010-07-13 Jones Thomas L Composition and method of treating a sore throat
US20080107747A1 (en) * 2006-10-23 2008-05-08 Roederer Joy E Pain relief composition
US20090028802A1 (en) * 2007-07-23 2009-01-29 Toru Hibi Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
KR101709904B1 (ko) 2009-05-19 2017-02-23 뉴로덤 엘티디 Dopa 데카르복실라제 억제제의 연속투여용 조성물
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
HUE047841T2 (hu) * 2010-11-15 2020-05-28 Neuroderm Ltd L-dopa, dopa dekarboxiláz inhibitorok, katekol-o-metil transzferáz inhibitorok folyamatos adagolására szolgáló készítmények
GB201021267D0 (en) 2010-12-15 2011-01-26 Reckitt Benckiser Healthcare Int Ltd Novel pharmaceutical formulation
TR201903492T4 (tr) 2012-06-05 2019-04-22 Neuroderm Ltd Apomorfin ve organik asitler içeren bileşimler ve bunların kullanım alanları.
GB201216893D0 (en) 2012-09-21 2012-11-07 Aesica Pharmaceuticals Ltd Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen
HUE064818T2 (hu) 2014-03-13 2024-04-28 Neuroderm Ltd Dopa dekarboxiláz inhibitor készítmények
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
CN110812331A (zh) * 2018-08-10 2020-02-21 北京普德康利医药科技发展有限公司 一种氟比洛芬咽部滞留颗粒
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
CN118125916A (zh) * 2022-09-23 2024-06-04 南京知和医药科技有限公司 一种s-(+)-氟比洛芬盐及其制备方法、药物组合物和用途

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CA1062721A (en) * 1975-12-15 1979-09-18 Anthony A. Sinkula Propionic acid derivatives
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
JPH0647532B2 (ja) * 1983-08-31 1994-06-22 ジ アツプジヨン カンパニ− 歯槽骨吸収の治療
ZA869433B (en) * 1985-12-16 1988-07-27 Cilag Ag Non-irritating suprofen solution
EP0321505A1 (de) * 1986-10-22 1989-06-28 The Upjohn Company Behandlung von gingivitis mit ibuprofen oder flurbiprofen
JPS63156715A (ja) * 1986-12-19 1988-06-29 Teisan Seiyaku Kk 即効性の徐放化製剤
JP2540581B2 (ja) * 1988-02-04 1996-10-02 三省製薬株式会社 外用剤
US4931473A (en) * 1989-02-15 1990-06-05 Richardson-Vicks Inc. Anesthetic oral compositions
ATE117892T1 (de) * 1989-08-17 1995-02-15 Sepracor Inc Orales s(+)-flurbiprofen- oder ketoprofenhaltiges mittel.
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
JP2738092B2 (ja) * 1989-11-17 1998-04-08 ライオン株式会社 口腔用組成物
JPH0426618A (ja) * 1990-05-21 1992-01-29 Japan Tobacco Inc トローチ剤
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
AU685741B2 (en) * 1992-12-04 1998-01-29 Mayor Pharmaceutical Laboratories, Inc. Sprayable analgesic composition and method of use
WO1994014476A1 (en) * 1992-12-21 1994-07-07 The Procter & Gamble Company Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
HUT76798A (en) * 1994-09-02 1997-11-28 Univ Virginia Commonwealth Composition alleviating pain, containing a non-narcotic analgesic and an analgesia enhancer
US5567733B1 (en) * 1995-04-27 1999-08-24 Jon G Dishler Irritation relief using nonsteroidal anti-inflammatory compounds
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GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
PT910339E (pt) * 1996-04-12 2005-05-31 Novadel Pharma Inc Aerossol polar bucal

Also Published As

Publication number Publication date
CN1148177C (zh) 2004-05-05
NO982294D0 (no) 1998-05-20
CA2238271A1 (en) 1997-05-29
AU2611997A (en) 1997-06-11
EP0862424B1 (de) 2003-10-22
RU2203655C2 (ru) 2003-05-10
ES2208768T3 (es) 2004-06-16
SK284092B6 (sk) 2004-09-08
EP0862424A1 (de) 1998-09-09
DK0862424T3 (da) 2003-12-29
AU707749B2 (en) 1999-07-22
NO982294L (no) 1998-07-20
CZ156598A3 (cs) 1998-08-12
SK66598A3 (en) 1998-12-02
HU225235B1 (en) 2006-08-28
BG64166B1 (bg) 2004-03-31
CN1207677A (zh) 1999-02-10
PT862424E (pt) 2004-02-27
GB9523833D0 (en) 1996-01-24
WO1997018802A1 (en) 1997-05-29
NO317287B1 (no) 2004-10-04
HUP0000180A3 (en) 2001-10-29
ATE252382T1 (de) 2003-11-15
HUP0000180A2 (hu) 2000-08-28
UA46807C2 (uk) 2002-06-17
BG102526A (en) 1999-02-26
US5889057A (en) 1999-03-30
CA2238271C (en) 2008-08-12
IL124568A0 (en) 1998-12-06
CZ289643B6 (cs) 2002-03-13
NZ322933A (en) 2000-02-28
DE69630460T2 (de) 2004-08-19
US6166083A (en) 2000-12-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB