DE69627056T2 - Verfahren zur Identifizierung und Isolierung von einem Molekül - Google Patents

Verfahren zur Identifizierung und Isolierung von einem Molekül Download PDF

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Publication number
DE69627056T2
DE69627056T2 DE69627056T DE69627056T DE69627056T2 DE 69627056 T2 DE69627056 T2 DE 69627056T2 DE 69627056 T DE69627056 T DE 69627056T DE 69627056 T DE69627056 T DE 69627056T DE 69627056 T2 DE69627056 T2 DE 69627056T2
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Prior art keywords
host cells
molecule
identifying
lysates
sample
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Expired - Lifetime
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DE69627056T
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DE69627056D1 (de
Inventor
Michael Pfreundschuh
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Ludwig Institute for Cancer Research New York
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Ludwig Institute for Cancer Research New York
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Priority claimed from US08/580,980 external-priority patent/US6025191A/en
Priority claimed from US08/644,116 external-priority patent/US6140464A/en
Application filed by Ludwig Institute for Cancer Research New York filed Critical Ludwig Institute for Cancer Research New York
Publication of DE69627056D1 publication Critical patent/DE69627056D1/de
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57438Specifically defined cancers of liver, pancreas or kidney
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
DE69627056T 1995-06-07 1996-06-07 Verfahren zur Identifizierung und Isolierung von einem Molekül Expired - Lifetime DE69627056T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/479,328 US5698396A (en) 1995-06-07 1995-06-07 Method for identifying auto-immunoreactive substances from a subject
US08/580,980 US6025191A (en) 1995-06-07 1996-01-03 Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof
US08/644,116 US6140464A (en) 1995-06-07 1996-05-10 Nonapeptides that bind a HLA-A2.1 molecule

Publications (2)

Publication Number Publication Date
DE69627056D1 DE69627056D1 (de) 2003-04-30
DE69627056T2 true DE69627056T2 (de) 2004-01-29

Family

ID=23903564

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69623014T Expired - Lifetime DE69623014T2 (de) 1995-06-07 1996-06-07 Verfahren zur identifizierung und isolierung von einem molekül und von diesem erkannte moleküle
DE69627056T Expired - Lifetime DE69627056T2 (de) 1995-06-07 1996-06-07 Verfahren zur Identifizierung und Isolierung von einem Molekül

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69623014T Expired - Lifetime DE69623014T2 (de) 1995-06-07 1996-06-07 Verfahren zur identifizierung und isolierung von einem molekül und von diesem erkannte moleküle

Country Status (11)

Country Link
US (2) US5698396A (de)
EP (1) EP0831879B1 (de)
JP (1) JP2002502354A (de)
CN (1) CN1136914C (de)
AT (2) ATE222116T1 (de)
CA (1) CA2223566C (de)
DE (2) DE69623014T2 (de)
DK (1) DK0831879T3 (de)
ES (1) ES2180782T3 (de)
PT (1) PT831879E (de)
WO (1) WO1996040209A1 (de)

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DE69623014D1 (de) 2002-09-19
AU6165296A (en) 1996-12-30
DE69627056D1 (de) 2003-04-30
ES2180782T3 (es) 2003-02-16
US5798264A (en) 1998-08-25
AU704109B2 (en) 1999-04-15
CN1136914C (zh) 2004-02-04
DE69623014T2 (de) 2003-05-08
CN1190894A (zh) 1998-08-19
DK0831879T3 (da) 2002-12-16
PT831879E (pt) 2002-12-31
ATE222116T1 (de) 2002-08-15
EP0831879A1 (de) 1998-04-01
JP2002502354A (ja) 2002-01-22
EP0831879B1 (de) 2002-08-14
WO1996040209A1 (en) 1996-12-19
CA2223566A1 (en) 1996-12-19
EP0831879A4 (de) 2000-01-26
US5698396A (en) 1997-12-16
ATE235248T1 (de) 2003-04-15
CA2223566C (en) 2002-09-03

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